The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Insomnia is associated with suicide attempt in middle-aged and older adults with depression
Open accessAbstract
BACKGROUND: Insomnia increases in prevalence with age, is strongly associated with depression, and has been identified as a risk factor for suicide in several studies. The aim of this study was to determine whether insomnia severity varies between those who have attempted suicide (n = 72), those who only contemplate suicide (n = 28), and those who are depressed but have no suicidal ideation or attempt history (n = 35). METHODS: Participants were middle-aged and older adults (age 44-87, M = 66 years) with depression. Insomnia severity was measured as the sum of the early, middle, and late insomnia items from the Hamilton Rating Scale for Depression. General linear models examined relations between group status as the independent variable and insomnia severity as the dependent variable. RESULTS: The suicide attempt group suffered from more severe insomnia than the suicidal ideation and non-suicidal depressed groups (p < 0.05). Differences remained after adjusting for potential confounders including demographics, cognitive ability, alcohol dependence in the past month, severity of depressed mood, anxiety, and physical health burden. Moreover, greater insomnia severity in the suicide attempt group could not be explained by interpersonal difficulties, executive functioning, benzodiazepine use, or by the presence of post-traumatic stress disorder. CONCLUSIONS: Our results suggest that insomnia may be more strongly associated with suicidal behavior than with the presence of suicidal thoughts alone. Accordingly, insomnia is a potential treatment target for reducing suicide risk in middle-aged and older adults.
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Persistent insomnia symptoms may result in unfavorable clinical outcome, e.g., increased suicide risk.
“Persistent insomnia symptoms may also result in unfavorable clinical outcome, e.g., increased suicide risk [14].”
From Effects of Antidepressants on Sleep (2017) · cites this paper as [14]
The Discussion reports an association between insomnia severity and suicide attempts in middle-aged and older adults with depression. However, it says chronicity was not assessed and the cross-sectional study cannot establish whether insomnia precedes or causes suicidal behavior. The source therefore supports increased risk as a possibility, but not the claim specifically about persistent symptoms resulting in that outcome. (LLM, conf=0.88)
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Cites
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Effects of Antidepressants on Sleep
Wichniak, A., Wierzbicka, A., Walęcka, M., & Jernajczyk, W. (2017) · Current Psychiatry Reports · doi:10.1007/s11920-017-0816-4 · Cited by 557
Metadata
- Authors
- Kay, D. B., Dombrovski, A. Y., Buysse, D. J., Reynolds, C. F., Begley, A., & Szanto, K.
- Affiliations
- University of Pittsburgh (US)
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 28
- Issue
- 4
- Pages
- 613-619
- ISSN
- 1041-6102 (ISSN-L)
- PMC
- PMC4808421
- OpenAlex
- W2193105650
- Cited by
- 76
- References
- 7
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 6 · 2023: 6 · 2022: 3 · 2021: 34 · 2020: 5 · 2019: 8 · 2018: 5 · 2017: 5
- FWCI
- 3.12
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Psychogeriatrics (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- ScholarsArchive (Brigham Young University) (submittedVersion)
- Funders
- National Institutes of Health (P30 MH090333, HL082610, UL1TR000005, P60 MD000207, UL1RR024153)
- Medical Center, University of Pittsburgh
- National Institute of Mental Health (K23 MH086620, R01 MH100095)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- insomnia, suicide attempts, depression, suicidal ideation, middle-aged and older adults, insomnia severity, suicide risk, benzodiazepine use, post-traumatic stress disorder, executive function, alcoholism
- MeSH terms
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Depression, Female, Humans, Sleep Initiation and Maintenance Disorders, Male, Middle Aged, Pennsylvania, Severity of Illness Index, Suicide, Attempted, Case-Control Studies, Suicidal Ideation
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