The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Psychotropic drug prescriptions in Western European nursing homes
Open accessAbstract
BACKGROUND: Despite the numerous warnings of European and national drug agencies as well as clinical guidelines since the year 2004, psychotropic drugs are still frequently used in dementia. A systematic review comparing the use of psychotropic drugs in nursing homes from different European countries is lacking. OBJECTIVE: The aim of this study was to examine prescription rates of psychotropic drug use in nursing home patients between different Western European countries since the first warnings were published. METHODS: A literature review was performed and the various psychotropic prescribing rates in European nursing homes were investigated. The prescription rates of antipsychotic and antidepressants were pooled per country. Other classes of psychotropic drugs could not be pooled because of the limited number of studies found. RESULTS: Thirty-seven studies on antipsychotic drug use and 27 studies on antidepressant drug use conducted in 12 different European countries. The antipsychotic use in nursing homes ranged from 12% to 59% and antidepressant use from 19% to 68%. The highest rates of antipsychotic drug prescription were found in Austria, Ireland, and Belgium while for antidepressants in Belgium, Sweden, and France. CONCLUSIONS: Despite warnings about the side effects and recommendation to focus on non-pharmacological interventions, antipsychotics and antidepressants are commonly used drugs in nursing homes. The data suggest that Norway does best with regards having a low antipsychotic drug usage. Studies are needed to explain the differences between Norway and other European countries.
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“Rates of prescribing are particularly high across care homes, where studies in the Western Europe have shown that up to 63% of residents are prescribed at least one psychotropic drug [5–8].”
From Stakeholders' views on the use of psychotropic medication in older people: a systematic review (2022) · cites this paper as [8]
In the citing paper
“Previous research has also shown that country of residence is more important than clinical factors in determining psychotropic use and this also suggests that prescribing habits, social, cultural, behavioural and regulatory factors play an important role [8, 87].”
From Stakeholders' views on the use of psychotropic medication in older people: a systematic review (2022) · cites this paper as [8]
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Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular dementia
Mühlbauer, V., Möhler, R., Dichter, M. N., Zuidema, S. U., Köpke, S., & Luijendijk, H. J. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013304.pub2 · Cited by 117
Antipsychotic deprescription for older adults in long-term care: the HALT study
Brodaty, H., Aerts, L., Harrison, F., Jessop, T., Cations, M., Chenoweth, L., Shell, A., Popovic, G. C., Heffernan, M., Hilmer, S., et al. (2018) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2018.05.002 · Cited by 104
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The economics of patient safety Part III: Long-term care
Bienassis, K. D., Nozal, A. L., & Klazinga, N. S. (2020) · OECD health working papers · doi:10.1787/be07475c-en · Cited by 76
Cioltan, H., Alshehri, S. O., Howe, C. L., Lee, J. K., Fain, M. J., Eng, H. J., Schachter, K., & Mohler, J. M. (2017) · BMC Geriatrics · doi:10.1186/s12877-017-0428-1 · Cited by 83
Metadata
- Authors
- Janus, S. I. M., van Manen, J. G., IJzerman, M. J., & Zuidema, S. U.
- Affiliations
- University of Twente (NL)
- University Medical Center Groningen (NL)
- Corresponding author
- Janus, Sarah I. M.
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2016-07-29
- Volume
- 28
- Issue
- 11
- Pages
- 1775-1790
- ISSN
- 1041-6102 (ISSN-L)
- 1741-203X
- OpenAlex
- W2491277325
- Cited by
- 110
- References
- 59
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 4 · 2023: 6 · 2022: 23 · 2021: 14 · 2020: 16 · 2019: 19 · 2018: 9 · 2017: 6 · 2016: 1
- FWCI
- 1.18
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- International Psychogeriatrics (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, cc-by-nc-nd)
- University of Twente Research Information (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- University of Twente Research Information (submittedVersion)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- psychotropic drugs, nursing homes, antipsychotic drugs, antidepressants, dementia, prescription rates, Western Europe, cross-national comparison, non-pharmacological treatment
- MeSH terms
- Potentially Inappropriate Medication List, Cross-Cultural Comparison, Dementia, Europe, Homes for the Aged, Humans, Nursing Homes, Psychotropic Drugs, Inappropriate Prescribing
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