The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS)
Abstract
Cognitive impairment occurs in roughly 50% of patients with multiple sclerosis (MS). It is well known that processing speed and episodic memory deficits are the most common neuropsychological (NP) sequelae in this illness. Consensus has emerged about the specific tests that prove most helpful for routine monitoring of MS associated cognitive impairment. The purpose of this study was to examine the validity of the Minimal Assessment of Cognitive Function in MS (MACFIMS), a recommended battery based on the findings of an international conference held in 2001. We tested 291 MS patients and 56 healthy controls. Frequencies of impairment paralleled those reported in previous work for both individual cognitive domains and general impairment. All tests were impaired in the MS group, and distinguished relapsing-remitting (RR) from secondary progressive (SP) course. Principle components analysis showed a distinct episodic memory component. Most of the MACFIMS tests discriminated disabled from employed patients. However, in regression models accounting for all NP tests, those emphasizing verbal memory and executive function were most predictive of vocational status. We conclude that the MACFIMS is a valid approach to routine NP assessment of MS patients. Future work is planned to determine its psychometric properties in a longitudinal study. (JINS, 2006, 12, 549–558.)
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
Kurtzke, J. F. (1983) · Neurology · doi:10.1212/wnl.33.11.1444 · Cited by 15,011
Delis-Kaplan Executive Function System
Delis, D. C., Kaplan, E., & Kramer, J. H. (2012) · PsycTESTS Dataset · doi:10.1037/t15082-000 · Cited by 2,683
Paced Auditory Serial-Addition Task: A Measure of Recovery from Concussion
Gronwall, D. M. A. (1977) · Perceptual and Motor Skills · doi:10.2466/pms.1977.44.2.367 · Cited by 2,395 · cited 1×
“, 2000), Brief Visuospatial Memory Test-Revised (BVMT-R; Benedict, 1997), Paced Auditory Serial Addition Test (PASAT; Gronwall, 1977), Symbol Digit Modalities Test (SDMT; Smith, 1982), and the Sorting Test from the Delis-Kaplan Executive Function System (DKEFS; Delis et al.”
MethodCognitive dysfunction in multiple sclerosis.: II. Impact on employment and social functioning
Rao, S. M., Leo, G. J., Ellington, L., Nauertz, T., Bernardin, L., & Unverzagt, F. (1991) · Neurology · doi:10.1212/wnl.41.5.692 · Cited by 890
Benedict, R. H. B., Wahlig, E., Bakshi, R., Fishman, I., Munschauer, F., Zivadinov, R., & Weinstock-Guttman, B. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2004.12.009 · Cited by 528
Self-citation
Cited by
Cognitive impairment in multiple sclerosis
Chiaravalloti, N. D., & DeLuca, J. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70259-x · Cited by 2,088
Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis
Rocca, M. A., Amato, M. P., De Stefano, N., Enzinger, C., Geurts, J. J., Penner, I.-K., Rovira, A., Sumowski, J. F., Valsasina, P., & Filippi, M. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70250-9 · Cited by 557
Cohen, J. A., Reingold, S. C., Polman, C. H., & Wolinsky, J. S. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70059-5 · Cited by 233
Multiple sclerosis and cognition: synaptic failure and network dysfunction
Di Filippo, M., Portaccio, E., Mancini, A., & Calabresi, P. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0053-9 · Cited by 205
Hou, B., Zhang, Y., Liang, P., He, Y., Peng, B., Liu, W., Han, S., Yin, J., & He, X. (2020) · Cell Death & Disease · doi:10.1038/s41419-020-2565-2 · Cited by 187
Metadata
- Authors
- BENEDICT, R. H. B., COOKFAIR, D., GAVETT, R., GUNTHER, M., MUNSCHAUER, F., GARG, N., & WEINSTOCK-GUTTMAN, B.
- Venue
- Journal of the International Neuropsychological Society
- Publisher
- Cambridge University Press (CUP)
- Published
- 2006-06-27
- Volume
- 12
- Issue
- 4
- Pages
- 549-558
- ISSN
- 1355-6177 (ISSN-L)
- 1469-7661
- OpenAlex
- W2167181885
- Cited by
- 798
- References
- 5
- FWCI
- 9.16
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS). https://app.cochat.ai/papers/10.1017/s1355617706060723
- The paper
- BENEDICT, R. H. B., COOKFAIR, D., GAVETT, R., GUNTHER, M., MUNSCHAUER, F., GARG, N., & WEINSTOCK-GUTTMAN, B. (2006). Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS). Journal of the International Neuropsychological Society. https://doi.org/10.1017/s1355617706060723
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.