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Cited by 798

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS)

BENEDICT, RALPH H.B., COOKFAIR, DIANE, GAVETT, REBECCA, GUNTHER, MARK, MUNSCHAUER, FREDERICK, GARG, NEETA, WEINSTOCK-GUTTMAN, BIANCA·2006·Journal of the International Neuropsychological Society

Abstract

Cognitive impairment occurs in roughly 50% of patients with multiple sclerosis (MS). It is well known that processing speed and episodic memory deficits are the most common neuropsychological (NP) sequelae in this illness. Consensus has emerged about the specific tests that prove most helpful for routine monitoring of MS associated cognitive impairment. The purpose of this study was to examine the validity of the Minimal Assessment of Cognitive Function in MS (MACFIMS), a recommended battery based on the findings of an international conference held in 2001. We tested 291 MS patients and 56 healthy controls. Frequencies of impairment paralleled those reported in previous work for both individual cognitive domains and general impairment. All tests were impaired in the MS group, and distinguished relapsing-remitting (RR) from secondary progressive (SP) course. Principle components analysis showed a distinct episodic memory component. Most of the MACFIMS tests discriminated disabled from employed patients. However, in regression models accounting for all NP tests, those emphasizing verbal memory and executive function were most predictive of vocational status. We conclude that the MACFIMS is a valid approach to routine NP assessment of MS patients. Future work is planned to determine its psychometric properties in a longitudinal study. (JINS, 2006, 12, 549–558.)

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Metadata

Authors
BENEDICT, R. H. B., COOKFAIR, D., GAVETT, R., GUNTHER, M., MUNSCHAUER, F., GARG, N., & WEINSTOCK-GUTTMAN, B.
Venue
Journal of the International Neuropsychological Society
Published
2006-06-27
Volume
12
Issue
4
Pages
549-558
ISSN
  • 1355-6177 (ISSN-L)
  • 1469-7661
OpenAlex
W2167181885
Cited by
798
References
5
FWCI
9.16
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS). https://app.cochat.ai/papers/10.1017/s1355617706060723
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BENEDICT, R. H. B., COOKFAIR, D., GAVETT, R., GUNTHER, M., MUNSCHAUER, F., GARG, N., & WEINSTOCK-GUTTMAN, B. (2006). Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS). Journal of the International Neuropsychological Society. https://doi.org/10.1017/s1355617706060723

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.