The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The project ENABLE II randomized controlled trial to improve palliative care for rural patients with advanced cancer: Baseline findings, methodological challenges, and solutions
Open accessAbstract
Objective: There is a paucity of randomized controlled trials (RCTs) to evaluate models of palliative care. Although interventions vary, all have faced a variety of methodological challenges including adequate recruitment, missing data, and contamination of the control group. We describe the ENABLE II intervention, methods, and sample baseline characteristics to increase intervention and methodological transparency, and to describe our solutions to selected methodological issues. Methods: Half of the participants recruited from our rural U.S. comprehensive cancer center and affiliated clinics were randomly assigned to a phone-based, nurse-led educational, care coordination palliative care intervention model. Intervention services were provided to half of the participants weekly for the first month and then monthly until death, including bereavement follow-up call to the caregiver. The other half of the participants were assigned to care as usual. Symptoms, quality of life, mood, and functional status were assessed every 3 months until death. Results: Baseline data of 279 participants were similar to normative samples. Solutions to methodological challenges of recruitment, missing data, and “usual care” control group contamination are described. Significance of results: It is feasible to overcome many of the methodological challenges to conducting a rigorous palliative care RCT.
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Cites
The functional assessment of cancer therapy scale: development and validation of the general measure
Cella, D. F., Tulsky, D. S., Gray, G., Sarafian, B., Linn, E., Bonomi, A., Silberman, M., Yellen, S. B., Winicour, P., & Brannon, J. (1993) · Journal of Clinical Oncology · doi:10.1200/jco.1993.11.3.570 · Cited by 6,020 · cited 3×
“Quality of life for the ENABLE II sample is more comparable to an original validation sample for the FACT-G with stage IV disease (mean¼ 80.7+15.0; Cella et al., 1993).”
BackgroundMethodInfluentialBrady, M. J., Cella, D. F., Mo, F., Bonomi, A. E., Tulsky, D. S., Lloyd, S. R., Deasy, S., Cobleigh, M., & Shiomoto, G. (1997) · Journal of Clinical Oncology · doi:10.1200/jco.1997.15.3.974 · Cited by 1,752 · cited 1×
“The FACIT-Pal consists of the FACT-G (Functional Assessment of Cancer Therapy–General), a general measure of quality of life, and the palliative care subscale (Pal), which assesses issues specifically relevant to palliative care (Brady et al., 1997; Lyons et al., in press).”
BackgroundMcMillan, S. C., Small, B. J., Weitzner, M., Schonwetter, R., Tittle, M., Moody, L., & Haley, W. E. (2006) · Cancer · doi:10.1002/cncr.21567 · Cited by 305
Research with families facing cancer: the challenges of accrual and retention
Northouse, L. L., Rosset, T., Phillips, L., Mood, D., Schafenacker, A., & Kershaw, T. (2006) · Research in Nursing & Health · doi:10.1002/nur.20128 · Cited by 96
Cited by
Bakitas, M., Lyons, K. D., Hegel, M. T., Balan, S., Brokaw, F. C., Seville, J., Hull, J. G., Li, Z., Tosteson, T. D., Byock, I. R., et al. (2009) · JAMA · doi:10.1001/jama.2009.1198 · Cited by 1,726
Self-citationEarly palliative care for adults with advanced cancer
Haun, M. W., Estel, S., Rücker, G., Friederich, H.-C., Villalobos, M., Thomas, M., & Hartmann, M. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011129.pub2 · Cited by 757
Bakitas, M. A., Dionne-Odom, J. N., Ejem, D. B., Wells, R., Azuero, A., Stockdill, M. L., Keebler, K., Sockwell, E., Tims, S., Engler, S., et al. (2020) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2020.2861 · Cited by 170
Self-citationTelephone interventions for symptom management in adults with cancer
Ream, E., Hughes, A. E., Cox, A., Skarparis, K., Richardson, A., Pedersen, V. H., Wiseman, T., Forbes, A., & Bryant, A. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007568.pub2 · Cited by 113
The role of digital health technology in rural cancer care delivery: A systematic review
Morris, B. B., Rossi, B., & Fuemmeler, B. (2022) · The Journal of Rural Health · doi:10.1111/jrh.12619 · Cited by 104
Metadata
- Authors
- Bakitas, M., Lyons, K. D., Hegel, M. T., Balan, S., Barnett, K. N., Brokaw, F. C., Byock, I. R., Hull, J. G., Li, Z., Mckinstry, E., Seville, J. L., & Ahles, T. A.
- Venue
- Palliative and Supportive Care
- Publisher
- Cambridge University Press (CUP)
- Published
- 2009-02-13
- Volume
- 7
- Issue
- 1
- Pages
- 75-86
- ISSN
- 1478-9515 (ISSN-L)
- 1478-9523
- OpenAlex
- W2170483105
- Cited by
- 188
- References
- 4
- FWCI
- 5.56
- Type
- journal article
- Language
- en
- Open access
- green
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- Bakitas, M., Lyons, K. D., Hegel, M. T., Balan, S., Barnett, K. N., Brokaw, F. C., Byock, I. R., Hull, J. G., Li, Z., Mckinstry, E., Seville, J. L., & Ahles, T. A. (2009). The project ENABLE II randomized controlled trial to improve palliative care for rural patients with advanced cancer: Baseline findings, methodological challenges, and solutions. Palliative and Supportive Care. https://doi.org/10.1017/s1478951509000108
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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