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Cited by 177

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Prevalence of suicide attempts in bipolar disorder: a systematic review and meta-analysis of observational studies

Open access
Dong, Min, Lu, Li, Zhang, Ling, Zhang, Qinge, Ungvari, Gabor S., Ng, Chee H., Yuan, Zhen, Xiang, Yifan, Wang, Gang, Xiang, Yu-Tao·2020·Epidemiology and Psychiatric Sciences

Abstract

Aims: Bipolar disorder (BD) is a severe psychiatric disorder associated with a high risk of suicide. This meta-analysis examined the prevalence of suicide attempts (SA) in patients with BD and its associated factors. Methods: A systematic literature search was conducted in the PubMed, PsycINFO, EMBASE and Web of Science databases from their inception to 11 June 2018. The prevalence of SA in BD was synthesised using the random-effects model. Results: The search identified 3451 articles of which 79 studies with 33 719 subjects met the study entry criteria. The lifetime prevalence of SA was 33.9% (95% CI 31.3–36.6%;I2= 96.4%). Subgroup and meta-regression analyses revealed that the lifetime prevalence of SA was positively associated with female gender, BD-I, BD Not Otherwise Specified and rapid cycling BD subtypes, income level and geographic region. Conclusion: This meta-analysis confirmed that SA is common in BD and identified a number of factors related to SA. Further efforts are necessary to facilitate the identification and prevention of SA in BD. Long-term use of mood stabilisers coupled with psycho-social interventions should be available to BD patients to reduce the risk of suicidal behaviour.

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Metadata

Authors
Dong, M., Lu, L., Zhang, L., Zhang, Q., Ungvari, G. S., Ng, C. H., Yuan, Z., Xiang, Y., Wang, G., & Xiang, Y.-T.
Venue
Epidemiology and Psychiatric Sciences
Published
2019-10-25
Volume
29
Pages
e63-e63
ISSN
  • 2045-7960 (ISSN-L)
  • 2045-7979
OpenAlex
W2981352576
Cited by
177
References
12
FWCI
2.84
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Prevalence of suicide attempts in bipolar disorder: a systematic review and meta-analysis of observational studies. https://app.cochat.ai/papers/10.1017/s2045796019000593
The paper
Dong, M., Lu, L., Zhang, L., Zhang, Q., Ungvari, G. S., Ng, C. H., Yuan, Z., Xiang, Y., Wang, G., & Xiang, Y.-T. (2020). Prevalence of suicide attempts in bipolar disorder: a systematic review and meta-analysis of observational studies. Epidemiology and Psychiatric Sciences. https://doi.org/10.1017/s2045796019000593

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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