The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
DNA Nanostructure-Decorated Surfaces for Enhanced Aptamer-Target Binding and Electrochemical Cocaine Sensors
Abstract
The sensitivity of aptamer-based electrochemical sensors is often limited by restricted target accessibility and surface-induced perturbation of the aptamer structure, which arise from imperfect packing of probes on the heterogeneous and locally crowded surface. In this study, we have developed an ultrasensitive and highly selective electrochemical aptamer-based cocaine sensor (EACS), based on a DNA nanotechnology-based sensing platform. We have found that the electrode surface decorated with an aptamer probe-pendant tetrahedral DNA nanostructure greatly facilitates cocaine-induced fusion of the split anticocaine aptamer. This novel design leads to a sensitive cocaine sensor with a remarkably low detection limit of 33 nM. It is also important that the tetrahedra-decorated surface is protein-resistant, which not only suits the enzyme-based signal amplification scheme employed in this work, but ensures high selectivity of this sensor when deployed in sera or other adulterated samples.
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Cites
In vitro selection of RNA molecules that bind specific ligands
Ellington, A. D., & Szostak, J. W. (1990) · Nature · doi:10.1038/346818a0 · Cited by 9,812
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Seeman, N. C. (2003) · Nature · doi:10.1038/nature01406 · Cited by 2,782
Drummond, T. G., Hill, M. G., & Barton, J. K. (2003) · Nature Biotechnology · doi:10.1038/nbt873 · Cited by 2,214
Self-assembly of a nanoscale DNA box with a controllable lid
Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Subramani, R., Mamdouh, W., Golas, M. M., Sander, B., Stark, H., Oliveira, C. L. P., et al. (2009) · Nature · doi:10.1038/nature07971 · Cited by 1,627
Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra
He, Y., Ye, T., Su, M., Zhang, C., Ribbe, A. E., Jiang, W., & Mao, C. (2008) · Nature · doi:10.1038/nature06597 · Cited by 1,304
Rapid Chiral Assembly of Rigid DNA Building Blocks for Molecular Nanofabrication
Goodman, R. P., Schaap, I. A. T., Tardin, C. F., Erben, C. M., Berry, R. M., Schmidt, C. F., & Turberfield, A. J. (2005) · Science · doi:10.1126/science.1120367 · Cited by 1,171
DNA Microarray Technology: Devices, Systems, and Applications
Heller, M. J. (2002) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.4.020702.153438 · Cited by 1,068
Fan, C., Plaxco, K. W., & Heeger, A. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1633515100 · Cited by 1,043
Self-citationLiu, J., & Lu, Y. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200502589 · Cited by 956
Cited by
Functional DNA Nanostructures for Theranostic Applications
Pei, H., Zuo, X., Zhu, D., Huang, Q., & Fan, C. (2014) · Accounts of Chemical Research · doi:10.1021/ar400195t · Cited by 409
Self-citationKelley, S. O., Mirkin, C. A., Walt, D. R., Ismagilov, R. F., Toner, M., & Sargent, E. H. (2014) · Nature Nanotechnology · doi:10.1038/nnano.2014.261 · Cited by 398
Optical aptasensors for quantitative detection of small biomolecules: A review
Feng, C., Dai, S., & Wang, L. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.03.014 · Cited by 300
Metadata
- Authors
- Wen, Y., Pei, H., Wan, Y., Su, Y., Huang, Q., Song, S., & Fan, C.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-08-29
- Volume
- 83
- Issue
- 19
- Pages
- 7418-7423
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2312820309
- Cited by
- 265
- References
- 42
- FWCI
- 6.82
- Type
- journal article
- Language
- en
- Open access
- closed
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