The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
In Vivo, Transcutaneous Glucose Sensing Using Surface-Enhanced Spatially Offset Raman Spectroscopy: Multiple Rats, Improved Hypoglycemic Accuracy, Low Incident Power, and Continuous Monitoring for Greater than 17 Days
Open accessAbstract
This paper presents the latest progress on quantitative, in vivo, transcutaneous glucose sensing using surface enhanced spatially offset Raman spectroscopy (SESORS). Silver film over nanosphere (AgFON) surfaces were functionalized with a mixed self-assembled monolayer (SAM) and implanted subcutaneously in Sprague-Dawley rats. The glucose concentration was monitored in the interstitial fluid of six separate rats. The results demonstrated excellent accuracy and consistency. Remarkably, the root-mean-square error of calibration (RMSEC) (3.6 mg/dL) and the root-mean-square error of prediction (RMSEP) (13.7 mg/dL) for low glucose concentration (<80 mg/dL) is lower than the current International Organization Standard (ISO/DIS 15197) requirements. Additionally, our sensor demonstrated functionality up 17 days after implantation, including 12 days under the laser safety level for human skin exposure with only one time calibration. Therefore, our SERS based sensor shows promise for the challenge of reliable continuous glucose sensing systems for optimal glycemic control.
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Cites
In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags
Qian, X., Peng, X.-H., Ansari, D. O., Yin-Goen, Q., Chen, G. Z., Shin, D. M., Yang, L., Young, A. N., Wang, M. D., & Nie, S. (2008) · Nature Biotechnology · doi:10.1038/nbt1377 · Cited by 2,201
Hypoglycaemia: the limiting factor in the glycaemic management of type I and type II diabetes.
Cryer, P. (2002) · Diabetologia · doi:10.1007/s00125-002-0822-9 · Cited by 794
Glucose sensors: a review of current and emerging technology
Oliver, N. S., Toumazou, C., Cass, A. E. G., & Johnston, D. G. (2009) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02642.x · Cited by 584
Surface enhanced spatially offset Raman spectroscopic (SESORS) imaging – the next dimension
Stone, N., Kerssens, M., Lloyd, G. R., Faulds, K., Graham, D., & Matousek, P. (2011) · Chemical Science · doi:10.1039/c0sc00570c · Cited by 183
Stone, N., Faulds, K., Graham, D., & Matousek, P. (2010) · Analytical Chemistry · doi:10.1021/ac100039c · Cited by 140
Cited by
Using Raman spectroscopy to characterize biological materials
Butler, H. J., Ashton, L., Bird, B., Cinque, G., Curtis, K., Dorney, J., Esmonde-White, K., Fullwood, N. J., Gardner, B., Martin-Hirsch, P. L., et al. (2016) · Nature Protocols · doi:10.1038/nprot.2016.036 · Cited by 1,309
SERS Nanoparticles in Medicine: From Label-Free Detection to Spectroscopic Tagging
Lane, L. A., Qian, X., & Nie, S. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00265 · Cited by 873
Surface-enhanced Raman spectroscopy: a half-century historical perspective
Yi, J., You, E.-M., Hu, R., Wu, D.-Y., Liu, G.-K., Yang, Z.-L., Zhang, H., Gu, Y., Wang, Y.-H., Wang, X., et al. (2025) · Chemical Society Reviews · doi:10.1039/d4cs00883a · Cited by 382
Raman Spectroscopy of Blood and Blood Components
Atkins, C. G., Buckley, K., Blades, M. W., & Turner, R. F. B. (2017) · Applied Spectroscopy · doi:10.1177/0003702816686593 · Cited by 292
Noninvasive Monitoring of Blood Glucose with Raman Spectroscopy
Pandey, R., Paidi, S. K., Valdez, T. A., Zhang, C., Spegazzini, N., Dasari, R. R., & Barman, I. (2017) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00472 · Cited by 290
In Vitro and In Vivo SERS Biosensing for Disease Diagnosis
Moore, T. J., Moody, A. S., Payne, T. D., Sarabia, G. M., Daniel, A. R., & Sharma, B. (2018) · Biosensors · doi:10.3390/bios8020046 · Cited by 161
Kong, K. V., Ho, C. J. H., Gong, T., Lau, W. K. O., & Olivo, M. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2013.12.062 · Cited by 81
Surface Enhanced Spatially Offset Raman Spectroscopy Detection of Neurochemicals Through the Skull
Moody, A. S., Baghernejad, P. C., Webb, K. R., & Sharma, B. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00985 · Cited by 56
Nicolson, F., Jamieson, L. E., Mabbott, S., Plakas, K., Shand, N. C., Detty, M. R., Graham, D., & Faulds, K. (2018) · Chemical Communications · doi:10.1039/c8cc04267e · Cited by 42
Metadata
- Authors
- Ma, K., Yuen, J. M., Shah, N. C., Walsh, J. T., Glucksberg, M. R., & Van Duyne, R. P.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-11-02
- Volume
- 83
- Issue
- 23
- Pages
- 9146-9152
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2003368278
- Cited by
- 184
- References
- 5
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- green
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