The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Oxidative Cleavage-Based Near-Infrared Fluorescent Probe for Hypochlorous Acid Detection and Myeloperoxidase Activity Evaluation
Abstract
A near-infrared (NIR) fluorescent probe was synthesized and demonstrated to be highly selective in reaction with hypochlorous acid (HOCl), an endogenous reactive oxygen species (ROS) produced by myeloperoxidase in neutrophils. The reaction with HOCl resulted in the NIR fluorescence quenching at 774 nm and the absorbance decreasing at 710 nm, accompanied by the appearance of a new absorption band at 520 nm. The reaction mechanism was carefully examined and proposed to proceed by initial formation of chlorohydrins and subsequent degradation. This NIR fluorescent probe was successfully applied as a selective and sensitive indicator for HOCl on the basis of either colorimetry or fluorometry, which showed detection limits of 0.13 and 0.70 μM, respectively. In addition, the molecular probe was further demonstrated for NIR fluorescence imaging of HOCl in cells and for evaluating the enzymatic activity of myeloperoxidase in the HOCl generation by measuring absorbance change.
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The Pecking Order of Free Radicals and Antioxidants: Lipid Peroxidation, α-Tocopherol, and Ascorbate
Buettner, G. R. (1993) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1993.1074 · Cited by 2,417
Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
Fang, F. C. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro1004 · Cited by 1,676
Cited by
Recent Development of Chemosensors Based on Cyanine Platforms
Sun, W., Guo, S., Hu, C., Fan, J., & Peng, X. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00001 · Cited by 1,109
Duan, C., Won, M., Verwilst, P., Xu, J., Kim, H. S., Zeng, L., & Kim, J. S. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b00224 · Cited by 322
Zhang, R., Zhao, J., Han, G., Liu, Z., Liu, C., Zhang, C., Liu, B., Jiang, C., Liu, R., Zhao, T., et al. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.5b12848 · Cited by 288
Recent progress in the development of fluorescent probes for the detection of hypochlorous acid
Zhang, Y.-R., Liu, Y., Feng, X., & Zhao, B.-X. (2017) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2016.08.066 · Cited by 264
A general approach to the design of high-performance near-infrared (NIR) D-π-A type fluorescent dyes
Luo, X., Li, J., Zhao, J., Gu, L., Qian, X., & Yang, Y. (2019) · Chinese Chemical Letters · doi:10.1016/j.cclet.2019.03.012 · Cited by 119
Metadata
- Authors
- Sun, M., Yu, H., Zhu, H., Ma, F., Zhang, S., Huang, D., & Wang, S.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-12-12
- Volume
- 86
- Issue
- 1
- Pages
- 671-677
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2057332733
- Cited by
- 230
- References
- 2
- FWCI
- 7.85
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Oxidative Cleavage-Based Near-Infrared Fluorescent Probe for Hypochlorous Acid Detection and Myeloperoxidase Activity Evaluation. https://app.cochat.ai/papers/10.1021/ac403603r
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- Sun, M., Yu, H., Zhu, H., Ma, F., Zhang, S., Huang, D., & Wang, S. (2014). Oxidative Cleavage-Based Near-Infrared Fluorescent Probe for Hypochlorous Acid Detection and Myeloperoxidase Activity Evaluation. Analytical Chemistry. https://doi.org/10.1021/ac403603r
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