The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Smartphone-Based Simultaneous pH and Nitrite Colorimetric Determination for Paper Microfluidic Devices
Open accessAbstract
In this work, an Android application for measurement of nitrite concentration and pH determination in combination with a low-cost paper-based microfluidic device is presented. The application uses seven sensing areas, containing the corresponding immobilized reagents, to produce selective color changes when a sample solution is placed in the sampling area. Under controlled conditions of light, using the flash of the smartphone as a light source, the image captured with the built-in camera is processed using a customized algorithm for multidetection of the colored sensing areas. The developed image-processing allows reducing the influence of the light source and the positioning of the microfluidic device in the picture. Then, the H (hue) and S (saturation) coordinates of the HSV color space are extracted and related to pH and nitrite concentration, respectively. A complete characterization of the sensing elements has been carried out as well as a full description of the image analysis for detection. The results show good use of a mobile phone as an analytical instrument. For the pH, the resolution obtained is 0.04 units of pH, 0.09 of accuracy, and a mean squared error of 0.167. With regard to nitrite, 0.51% at 4.0 mg L(-1) of resolution and 0.52 mg L(-1) as the limit of detection was achieved.
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Beyond the lateral flow assay: A review of paper-based microfluidics
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Metadata
- Authors
- Lopez-Ruiz, N., Curto, V. F., Erenas, M. M., Benito-Lopez, F., Diamond, D., Palma, A. J., & Capitan-Vallvey, L. F.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-09-09
- Volume
- 86
- Issue
- 19
- Pages
- 9554-9562
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2319874642
- Cited by
- 423
- References
- 19
- FWCI
- 15.73
- Type
- journal article
- Language
- en
- Open access
- green
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