The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Ultrasensitive DNA Detection Using Oligonucleotide−Silver Nanoparticle Conjugates
Abstract
Oligonucleotide-gold nanoparticle (OGN) conjugates are powerful tools for the detection of target DNA sequences due to the unique properties conferred upon the oligonucleotide by the nanoparticle. Practically all the research and applications of these conjugates have used gold nanoparticles to the exclusion of other noble metal nanoparticles. Here we report the synthesis of oligonucleotide-silver nanoparticle (OSN) conjugates and demonstrate their use in a sandwich assay format. The OSN conjugates have practically identical properties to their gold analogues and due to their vastly greater extinction coefficient both visual and absorption analyses can occur at much lower concentrations. This is the first report of OSN conjugates being successfully used for target DNA detection and offers improved sensitivity which is of interest to a range of scientists.
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Cites
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Cited by
Xu, W., Xue, X., Li, T., Zeng, H., & Liu, X. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200901772 · Cited by 382
Multiplex in vitro detection using SERS
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Self-citationMotion-based DNA detection using catalytic nanomotors
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Plasmonic colorimetric and SERS sensors for environmental analysis
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Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnostics
Wang, H.-N., Fales, A. M., Zaas, A. K., Woods, C. W., Burke, T., Ginsburg, G. S., & Vo-Dinh, T. (2013) · Analytica Chimica Acta · doi:10.1016/j.aca.2013.05.017 · Cited by 36
Metadata
- Authors
- Thompson, D. G., Enright, A., Faulds, K., Smith, W. E., & Graham, D.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-02-29
- Volume
- 80
- Issue
- 8
- Pages
- 2805-2810
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2002112662
- Cited by
- 259
- References
- 13
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- closed
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