The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Scanometric DNA Array Detection with Nanoparticle Probes
Abstract
A method for analyzing combinatorial DNA arrays using oligonucleotide-modified gold nanoparticle probes and a conventional flatbed scanner is described here. Labeling oligonucleotide targets with nanoparticle rather than fluorophore probes substantially alters the melting profiles of the targets from an array substrate. This difference permits the discrimination of an oligonucleotide sequence from targets with single nucleotide mismatches with a selectivity that is over three times that observed for fluorophore-labeled targets. In addition, when coupled with a signal amplification method based on nanoparticle-promoted reduction of silver(I), the sensitivity of this scanometric array detection system exceeds that of the analogous fluorophore system by two orders of magnitude.
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Citations
Cites
Thermodynamics and NMR of Internal G·T Mismatches in DNA
Allawi, H. T., & SantaLucia, J. (1997) · Biochemistry · doi:10.1021/bi962590c · Cited by 623
Cited by
Shape‐Controlled Synthesis of Metal Nanocrystals: Simple Chemistry Meets Complex Physics?
Xia, Y., Xiong, Y., Lim, B., & Skrabalak, S. E. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200802248 · Cited by 5,702
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Self-citationPhotoinduced Conversion of Silver Nanospheres to Nanoprisms
Jin, R., Cao, Y., Mirkin, C. A., Kelly, K. L., Schatz, G. C., & Zheng, J. G. (2001) · Science · doi:10.1126/science.1066541 · Cited by 3,384
Self-citationGhosh, S. K., & Pal, T. (2007) · Chemical Reviews · doi:10.1021/cr0680282 · Cited by 2,782
Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins
Nam, J.-M., Thaxton, C. S., & Mirkin, C. A. (2003) · Science · doi:10.1126/science.1088755 · Cited by 2,390
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Metadata
- Authors
- Taton, T. A., Mirkin, C. A., & Letsinger, R. L.
- Venue
- Science
- Published
- 2000-09-08
- Volume
- 289
- Issue
- 5485
- Pages
- 1757-1760
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2170347395
- Cited by
- 2,411
- References
- 1
- FWCI
- 25.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Taton, T. A., Mirkin, C. A., & Letsinger, R. L. (2000). Scanometric DNA Array Detection with Nanoparticle Probes. Science. https://doi.org/10.1126/science.289.5485.1757
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
