Cited by 119Spectroscopy and Chemometric AnalysesScientific Measurement and Uncertainty EvaluationStatistical Methods and Applications

Logarithmic Data Processing Can Be Used Justifiably in the Plotting of a Calibration Curve

Kong, Dezhao, Zhao, Jun, Tang, Sheng, Shen, Wei, Lee, Hian Kee·2021·Analytical Chemistry

Abstract

The article is a response to a recent opinion piece that log concentration values should not be applied in analytical chemistry. An essential aim in the development of analytical chemistry methods is to obtain more sensitive and accurate detection values. For the application of chemical analysis methods, the obtained experiment data need to fit with the mathematical functions in the first place. As influenced by different detection principles and analytical methods, data can be displayed in a coordinate system with two linear axes for linear function fitting, or the data can first be taken through a logarithmic transformation and then for function fitting. Using raw data or data after logarithmic transformation primarily depends on analytical principles, without special rules of data formats. For example, ultraviolet-visible spectrophotometric data are more suitable for direct linear fitting. However, enzyme-catalyzed reaction or electrochemical data in logarithmic form are more appropriate for function fitting. This transformation of data form will not affect the soundness of fit statistics; rather, it simplifies the complexity of function analysis and calculation, which are the essence of analytical chemistry. In this brief article, we provide justification and legitimacy of the application of logarithmic processing in various fields of quantitative analytical chemistry.

Integrity signals

Registry

Crossref · 10.1021/acs.analchem.1c02011

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Kong, D., Zhao, J., Tang, S., Shen, W., & Lee, H. K.
Affiliations
  • Jiangsu University of Science and Technology (CN)
  • National University of Singapore (SG)
Corresponding author
  • Tang, Sheng
  • Lee, Hian Kee
Venue
Analytical Chemistry
Published
2021-08-30
Volume
93
Issue
36
Pages
12156-12161
ISSN
  • 0003-2700 (ISSN-L)
  • 1520-6882
OpenAlex
W3196989348
Cited by
119
References
33
Citations by year
2026: 15 · 2025: 24 · 2024: 35 · 2023: 29 · 2022: 13 · 2021: 3
FWCI
10.00
Type
journal article
Language
en
Open access
closed
Locations
  • Analytical Chemistry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Natural Science Foundation of Jiangsu Province (BK20170570, BK20180979)
  • National Natural Science Foundation of China (21605105, 21705060, 32001804)
  • Emerging science and technology innovation team funding of JUST (1182921902)
Topics
  • Physical Sciences › Chemistry › Analytical Chemistry › Spectroscopy and Chemometric Analyses
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Scientific Measurement and Uncertainty Evaluation
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Applications
Keywords
logarithmic transformation, function fitting, data transformation, UV-Vis spectroscopy, enzymatic reactions, electrochemical data, detection sensitivity, quantitative analysis
MeSH terms
Calibration

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review