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Cited by 497

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Hydrogels for Therapeutic Delivery: Current Developments and Future Directions

Open access
Buwalda, Sytze J., Vermonden, Tina, Hennink, Wim E.·2017·Biomacromolecules

Abstract

Hydrogels are attractive materials for the controlled release of therapeutics because of their capacity to embed biologically active agents in their water-swollen network. Recent advances in organic and polymer chemistry, bioengineering and nanotechnology have resulted in several new developments in the field of hydrogels for therapeutic delivery. In this Perspective, we present our view on the state-of-the-art in the field, thereby focusing on a number of exciting topics, including bioorthogonal cross-linking methods, multicomponent hydrogels, stimuli-responsive hydrogels, nanogels, and the release of therapeutics from 3D printed hydrogels. We also describe the challenges that should be overcome to facilitate translation from academia to the clinic and last, we share our ideas about the future of this rapidly evolving area of research.

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Crossref · 10.1021/acs.biomac.6b01604

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Metadata

Authors
Buwalda, S. J., Vermonden, T., & Hennink, W. E.
Venue
Biomacromolecules
Published
2017-01-10
Volume
18
Issue
2
Pages
316-330
ISSN
  • 1525-7797 (ISSN-L)
  • 1526-4602
OpenAlex
W2562468696
Cited by
497
References
10
FWCI
16.88
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Hydrogels for Therapeutic Delivery: Current Developments and Future Directions. https://app.cochat.ai/papers/10.1021/acs.biomac.6b01604
The paper
Buwalda, S. J., Vermonden, T., & Hennink, W. E. (2017). Hydrogels for Therapeutic Delivery: Current Developments and Future Directions. Biomacromolecules. https://doi.org/10.1021/acs.biomac.6b01604

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.