Biological Utility of Fluorinated Compounds: from Materials Design to Molecular Imaging, Therapeutics and Environmental Remediation

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

Wang, J., Sánchez‐Roselló, M., Aceña, J. L., del Pozo, C., Sorochinsky, A. E., Fustero, S., Soloshonok, V. A., & Liu, H. (2013) · Chemical Reviews · doi:10.1021/cr4002879 · Cited by 4,902

Doxil® — The first FDA-approved nano-drug: Lessons learned

Barenholz, Y. (. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.020 · Cited by 4,792

Applications of Fluorine in Medicinal Chemistry

Gillis, E. P., Eastman, K. J., Hill, M. D., Donnelly, D. J., & Meanwell, N. A. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b00258 · Cited by 3,692

Time Course of Lung Changes at Chest CT during Recovery from Coronavirus Disease 2019 (COVID-19)

Pan, F., Ye, T., Sun, P., Gui, S., Liang, B., Li, L., Zheng, D., Wang, J., Hesketh, R. L., Yang, L., et al. (2020) · Radiology · doi:10.1148/radiol.2020200370 · Cited by 2,915

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

Zhou, Y., Wang, J., Gu, Z., Wang, S., Zhu, W., Aceña, J. L., Soloshonok, V. A., Izawa, K., & Liu, H. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00392 · Cited by 2,843

Combination therapy in combating cancer

Mokhtari, R. B., Homayouni, T. S., Baluch, N., Morgatskaya, E., Kumar, S., Das, B., & Yeger, H. (2017) · Oncotarget · doi:10.18632/oncotarget.16723 · Cited by 2,543

The COVID‐19 epidemic

Velavan, T. P., & Meyer, C. G. (2020) · Tropical Medicine & International Health · doi:10.1111/tmi.13383 · Cited by 2,464

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Fenton, S. E., Ducatman, A., Boobis, A., DeWitt, J. C., Lau, C., Ng, C., Smith, J. S., & Roberts, S. M. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4890 · Cited by 2,445

Chest CT for Typical Coronavirus Disease 2019 (COVID-19) Pneumonia: Relationship to Negative RT-PCR Testing

Xie, X., Zhong, Z., Zhao, W., Zheng, C., Wang, F., & Liu, J. (2020) · Radiology · doi:10.1148/radiol.2020200343 · Cited by 1,960

Desulfurizative Fluorination of N ‐CF 3 Thioformamides for the Efficient Synthesis of N (CF 3 )(CF 2 H) Amines with Enhanced Stability

Wycich, G., Ponce‐de‐León, J., Liu, L., & Schoenebeck, F. (2025) · Angewandte Chemie · doi:10.1002/ange.202506154 · Cited by 1

Packing structures and piezochromic properties engineering through F functionalization in 4-position substituted coumarin based organic luminogens

Yang, M., Guo, J., Fu, S., Zhang, Y., Yang, L., Li, Q., Bao, Y., & Wang, C. (2025) · Dyes and Pigments · doi:10.1016/j.dyepig.2025.113055 · Cited by 1

Fluorinated and Energetic Polyurethanes for High-Performance Energetic CompositesPreprint

Tang, G., Wang, H., Xu, Y., Chen, D., Wang, D., Luo, Y., & Li, X. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4048709 · Cited by 1

The Aminated Covalent Organic Polymers for Reversible Removal of Concurrent Perfluorooctane Sulfonate and DichromatePreprint

Wang, R., Kong, K., Cheng, B., Liang, J., & Guo, Y. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4072295 · Cited by 1

The Fluorine Toolbox: from Molecular Design to Advanced BatteriesPreprint

Wang, Y., Wu, Z., Makhlooghiazad, F., Zhu, Y., Wang, L., Hawker, C. J., Whittaker, A. K., Forsyth, M., & Zhang, C. (2023) · ChemRxiv · doi:10.26434/chemrxiv-2023-zj9ld · Cited by 1

Alemania renuncia al tren de levitación magnética

del Val, Y. (2008) · Vía libre

Fluorinated Covalent-Organic Polymers as Stationary Phase for Analysis of Organic Fluorides by Open-Tubular Capillary ElectrochromatographyPreprint

Sun, W., Liu, Y., Li, Z., Zhou, W., & Chen, Z. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4091347

Copper (I)‐BOX Catalyzed Asymmetric 3‐Component Reaction for the Synthesis of Trifluoromethylated Propargylic Ethers and Anilines**

Ramirez, N. P., & Waser, J. (2023) · Angewandte Chemie · doi:10.1002/ange.202305776

Tuning catalyst performance in asymmetric carbene transfer toward CF3-cyclopropenes

Marie, N., & Cahard, D. (2023) · Chem Catalysis · doi:10.1016/j.checat.2023.100665

(±)-N-(1,2-Bis(3,4-dimethoxyphenyl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

Manolov, S. P., Bojilov, D. G., Ivanov, I., & Nedialkov, P. T. (2023) · Molbank · doi:10.3390/m1679

Make a break with polyphosphoesters: From sequence control to biodegradable polymers and biomedical materials

Rheinberger, T. (2023) · doi:10.3990/1.9789036557412

Nickel‐Catalyzed Selective C(sp2)−F Bond Alkylation of Industrially Relevant Hydrofluoroolefin HFO‐1234yf

Luo, Y., Wang, M., Yu, L., & Zhang, X. (2023) · Angewandte Chemie · doi:10.1002/ange.202308690

Insights into Cytochrome P450 Enzyme Catalyzed Defluorination of Aromatic Fluorides

Zhang, Y., Mokkawes, T., & de Visser, S. P. (2023) · Angewandte Chemie · doi:10.1002/ange.202310785

Semisynthesis, characterization, and biological evaluation of fluorinated analogues of the spirobisnaphthalene, diepoxin-η

Pourhadi, H., El‐Elimat, T., Rangel‐Grimaldo, M., Graf, T. N., Falkinham, J. O., Khin, M., Burdette, J. E., Ezzone, N. P. M., Jeyaraj, J. G., de Blanco, E. J. C., et al. (2023) · Tetrahedron Letters · doi:10.1016/j.tetlet.2023.154857

Palladium‐Catalyzed Carbonylative Multicomponent Fluoroalkylation of 1,3‐Enynes: Concise Construction of Diverse Cyclic Compounds

Kuai, C., Teng, B., & Wu, X. (2023) · Angewandte Chemie · doi:10.1002/ange.202318257

2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy

Das, S., McIvor, C., Greener, A., Suwita, C., Argent, S. P., & O'Duill, M. L. (2024) · Angewandte Chemie · doi:10.1002/ange.202410954

Mechanically deformable organic ferroelectric crystal with adaptive shape lockingPreprint

Zhang, Y., Huang, P., Ni, H., Luo, J., Teri, G., Jia, Q., Zhuang, B., Wang, C., Zhang, Z., & Fu, D. (2024) · Research Square · doi:10.21203/rs.3.rs-4653096/v1

Hypervalent Iodine Mediated Ring-Opening 1,3-Difluorination of Benzylidenecyclopropanes

Huang, L.-L., Li, J., Sun, Q., Li, Q., Zhao, G.-Y., & Wang, H. (2024) · Synthesis · doi:10.1055/a-2373-0304

The crystal structure of 3-(6-fluoro-1H-indol-3-yl)-1-methylquinoxalin-2(1H)-one, C17H12FN3O

Ni, H.-C., Zhao, M., Li, W., Liu, Z.-X., Shao, L.-L., & Chen, M. (2024) · Zeitschrift für Kristallographie - New Crystal Structures · doi:10.1515/ncrs-2024-0234

Synthesis of 4-fluoroisocoumarins by copper-catalyzed annulation of 2-halobenzoic acids and 2-fluoro-1,3-diketones

Sakagami, H., Tsubouchi, A., & Saito, A. (2024) · Journal of Fluorine Chemistry · doi:10.1016/j.jfluchem.2024.110355

Competition of C–F, C–S, and S–F Bond Activation in SF5CF3 Using N‐Heterocyclic Olefins Derivatives: A Computational Study

Xu, X., & Xie, X. (2024) · Journal of Physical Organic Chemistry · doi:10.1002/poc.4675

19 F‐MRI: From Molecular Design to In Vivo Applications

Chirizzi, C., Dichiarante, V., Bombelli, F. B., & Metrangolo, P. (2024) · Patai's chemistry of functional groups · doi:10.1002/9780470682531.pat1009

Transition-metal-free synthesis of C3,5-difunctionalized oxindole derivatives

Liu, Y., Zhang, P., Feng, L., Zhang, Z., & Liang, T. (2025) · Organic Chemistry Frontiers · doi:10.1039/d4qo02428a

Future and Innovations in Medical Physics

Ayet, A. K., Faleh, M. S., Hamid, S. A., & Alawi, A. M. A. (2025) · Bright Sky Publications eBooks · doi:10.62906/bs.book.365

Nickel(II) Chloride Catalyzed and Tetrahydroxydiboron Promoted Denitrative Difluoroalkylation of β‐Nitrovinylarene

Zhong, S., Yang, Y., Ren, X., Zhao, W., & Wang, G. (2025) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.202500037

In situ observation of soft X-ray-triggered nanoscale phase transitions in perfluorocarbon microdroplets

Ji, Y., Wang, Y., Fang, M., Zhou, L., Wang, X., Guan, N., Hu, J., Gao, Y., Zhang, Y., & Zhang, L. (2025) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2025.138314

Identification of Mirror Neuron Cells Using Imaging Approaches

Alkhatib, A. J. (2025) · Springer eBooks · doi:10.1007/978-981-95-1225-6_2

Direct S-difluoromethylation of thiols: A facile synthetic route to difluoromethyl thioethers

Aldulaimi, A., Saeed, S. M., Menon, S. V., Taher, W. M., Saber, R. Y., Ray, S., Jayabalan, K., Sinha, A., Alwan, M., & Sharma, R. (2025) · Journal of Fluorine Chemistry · doi:10.1016/j.jfluchem.2025.110475

Organocatalytic Direct Csp 3 −H Difluoroalkylation of N ‐Aryltetrahydroisoquinoline

Luo, W., Peng, Y., Mei, Z., Chen, D., Cao, X., & Zhang, Y. (2025) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.202500547

Conventional Technologies for Removal of PFAS from Water Matrices

Chowdhury, S. D., Mishra, S. K., Bhunia, P., Surampalli, R. Y., & Zhang, T. C. (2025) · Wiley eBooks · doi:10.1002/9781394343935.ch12

Substitution of CH 3 by CH 2 F in 2‐Methylerythritol Cyclodiphosphate Triggers Potent Inhibition of IspG with Concomitant Fluoride Ion Expulsion

Witjaksono, C., Herrscher, V., Jobelius, H., Noël, N., Massicot, F., Vasse, J., Behr, J., & Seemann, M. (2025) · Chemistry - A European Journal · doi:10.1002/chem.202502471

Investigation of flocculation performance and mechanism of soluble fluoride removal from Industrial wastewater using polyaluminum lanthanum chloridePreprint

Sun, Y., Ji, Y., Hu, Z., Sun, W., Jun, Z., & Shah, K. J. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5703285

Design, Synthesis, and Anti‐Glioblastoma Activity Evaluation of N,N‐ Di(prop‐2‐yn‐1‐yl)‐4‐(trifluoromethyl)pyrimidin‐2‐amines and Their Bis‐Triazole Derivatives

Gritzenco, F., Krindges, M., Araújo, J. N., Zamin, L. L., Martins, M. A. P., Zanatta, N., & Bonacorso, H. G. (2025) · ChemistrySelect · doi:10.1002/slct.202504334

Organoiodine-Catalyzed Desymmetric Fluorolactonization of α,α-Diallylcarboxylic Acids to Access α-Quaternary Fluorinated Lactones

Chen, J., Li, J., & Li, X. (2025) · Organic Letters · doi:10.1021/acs.orglett.5c04358

Advances and challenges in the synthesis of N-fluoroalkyl compounds

Jiang, L., & Yi, W. (2025) · Science China Chemistry · doi:10.1007/s11426-025-3144-1

Additional file 1 of Intensity-adjustable pain management with prolonged duration based on phase-transitional nanoparticles-assisted ultrasound imaging-guided nerve blockade

Qiao, B., Song, X., Zhang, W., Xu, M., Zhuang, B., Li, W., Guo, H., Wu, W., Huang, G., Zhang, M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21622901

Photoredox-Catalyzed Defluorinative [4 + 2] Cycloaddition of α-Fluoro-β-keto Esters and Alkynes by Single Photosensitizer

Liu, R.-X., Yang, X., Li, H., Zhao, J., Song, Y., Meng, Q., & Niu, X. (2025) · Organic Letters · doi:10.1021/acs.orglett.5c04612

Mitochondria-targeted lipid nanoparticles to rescue mitochondrial complex I deficiency for Leber’s hereditary optic neuropathy therapy

Zhao, M., Liu, H.-N., Xie, H.-X., Yu, H.-Y., Yang, J., Liu, N.-H., Chen, J.-Q., Qie, L.-X., Yi, Z.-J., Zhou, T., et al. (2026) · Chinese Chemical Letters · doi:10.1016/j.cclet.2026.112360

Integration of Time‐Gated Luminescence and 19 F Magnetic Resonance in Lanthanide Complexes‐Based Probes for Quantitative Imaging of Mitochondrial Superoxide Anions

Zhang, X., Kong, D., Song, B., Huang, Y., & Yuan, J. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202505101

SABRE Hyperpolarized Multichannel 19 F NMR for Sensitive Detection of Multiple Disease Marker Enzymes on a Benchtop NMR

Zheng, L., Peng, Q., Sun, H., Deng, J., Jiang, Y., Xiong, Y., Chen, L., Cui, X., Lin, H., Chen, Z., et al. (2026) · Angewandte Chemie · doi:10.1002/ange.202517348

Regio- and Stereoselective Synthesis of CF 3 -Containing 1,2- and 1,1-Diarylethenes. Switchable Reaction of β-Halo-β-(trifluoromethyl)styrenes with Boronic Acids

Muzalevskiy, V. M., Sizova, Z. A., Vasil’ev, A. A., & G., V. G. V. (2026) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.5c02697

Photocatalytic Divergent Trifluoromethylthiolation of N ‐Sulfonylacrylamides Enabling Access to SCF 3 ‐Substituted Alkenes and Oxindoles

Zhu, C., Shen, Y., Wang, Z., Wei, N., & Xie, J. (2026) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.70283

Expeditious Synthesis of 2‐Deoxy‐2‐perfluoroalkyl Glycosides

Cao, S., Zhang, H., Zhu, N., Xu, P., Chen, X., Yu, B., & Zhang, X. (2026) · Angewandte Chemie · doi:10.1002/ange.1824435

Substrate-controlled divergent synthesis of substituted carbazoles through a cascade reaction of 2-alkenylindoles with α,β-unsaturated ketones

Yang, S., Wang, M., Jiang, H., Wang, R., Xing, Y., Luo, S., & Ding, Q. (2026) · Organic & Biomolecular Chemistry · doi:10.1039/d6ob00081a

Fluoroalkylated antimicrobial peptides enables cytosolic delivery and eradication of intracellular Staphylococcus aureus

Gao, T., Liu, T., Shen, J., Bao, B., Shi, S., Lin, J., & Zheng, X. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03978-8

Fluoroalkyl Acetaldehydes‐Versatile Fluorinated Building Blocks for the Synthesis of Diverse Fluoroalkylated Compounds

Niu, T., Zhang, C., Zhang, R., Lou, X., Gao, C., Wang, Y., Li, Q., Wei, H., Zhang, X., Jiang, L., et al. (2026) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.70360

Synthesis of ( E )‐β‐ SF 5 ‐Styrenes via a Heck Reaction of in situ Generated Vinylsulfur Pentafluoride †

DeGrâce, N., & Paquin, J. (2026) · Chinese Journal of Chemistry · doi:10.1002/cjoc.70547

Electrochemistry Reveals the Accelerating Effect of Fluorinated Compounds on Early-Stage Amyloid Fibril Aggregation

Ren, G., Wang, X., Cai, Y., Yin, Y., Wang, T., Wang, Y., Wei, H., & Zhang, M. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.5c07745

Pd(II)‐Catalyzed Transient Directing Group‐Assisted Regioselective Diverse C4–H Fluoroalkoxylation of Indoles

Xu, X., Jia, W., Heng, X., Shi, H., & Wu, N. (2026) · ChemistrySelect · doi:10.1002/slct.202506496

Catalyst and additive-free electrophilic trifluoromethylthiolation for the synthesis of CF3S-substituted indole and its derivatives in water

Wang, X., Zhang, P., Han, C., & Zhang, Y. (2026) · Journal of Fluorine Chemistry · doi:10.1016/j.jfluchem.2026.110564

Next-generation epidermal patches: Bridging 3D and multidimensional printing for biomedical and personal care innovations

El-Khordagui, L. K., El-Habashy, S. E., Simchi, A., Tohamy, H. S., Focarete, M. L., Rea, M., Lisa, L. D., Barman, S. R., Nain, A., Catanzano, O., et al. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2026.03.054

Fluorinated Nitrogen Compounds : Design, Synthesis and Applications

Yang, Y. (2024) · theses.fr (ABES) · doi:10.70675/389b3254z2659z40f4zac89za9f3044269ec

Breaking the Hypoxia Barrier: Supramolecular Nanoassemblies Empower Photodynamic Therapy of Tumors

Peng, Y., Shi, C., Cao, Y., Shi, L., Fang, F., & Chen, X. S. (2026) · Angewandte Chemie · doi:10.1002/ange.202525238

Enantiodivergent difluoroalkylation of alkenes via photoenzymatic catalysis

Xu, J., Shen, Z., Wang, H., Gao, Y., Gao, J., Zhou, J., & Gu, Y. (2026) · Organic Chemistry Frontiers · doi:10.1039/d6qo00279j

Trifluorination of 1,1-Diarylethenes Using Selectfluor/HF Reagent and Experimental Evidence for a Single Electron Transfer Mechanism

Kitamura, T., Oyamada, J., Higashi, M., & Kishikawa, Y. (2026) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.6c00562

Synthesis of Acyl Fluorides Using the Tribromoisocyanuric Acid (TBCA)/Triphenylphosphine/HF.Pyridine

Bragueroli, H. D. S., Silva, P. H. A., Sousa, J. M. C., Chaffin, V. O., Henrique, F. J. F. S., de Mattos, M. C. S., & Esteves, P. M. (2026) · Israel Journal of Chemistry · doi:10.1002/ijch.70027

Stereospecific Dehydroxytrifluoromethoxylation of Alcohols with 2,4‐Dinitro(trifluoromethoxy)benzene

Peng, Y., Guo, H., Zhang, Z., Song, C., & Li, J. (2026) · Chinese Journal of Chemistry · doi:10.1002/cjoc.70626

Synthesis of N-trifluoromethyl indoles via a modified fluorinative Fukuyama-type cyclization of o-alkenyl arylisocyanides

Wu, J., Fu, J.-L., Lin, S., Liu, H., Qin, Q.-H., Wang, H., & Li, Q. (2026) · Chinese Chemical Letters · doi:10.1016/j.cclet.2026.113133

Visible-Light-Promoted Trifluoromethylation/Ring-Opening Reaction of Vinylcyclopropanes by an EDA Complex

Ren, Y., Wang, K. P., Zhang, B., Wang, J., Huang, D., & Hu, Y. (2026) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.6c00775

Synthesis of N-CF 3 Amides and Ureas from N-CF 3 Secondary Amines and Acyl Chlorides

Wang, J., Wang, L., Feng, Z., Yi, W., & Jiang, L. (2026) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.6c01091

Visible-Light-Induced Radical Cascade Cyclization of 1,7-Enynes to Access CF2-Containing Indenoquinolines by an Electron Donor

Chen, Z. F., Peng, Y., Zhang, S.-P., Yang, W., & Zhang, Y. (2026) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.6c01033

Electrochemical monitoring of PFOA in water using a Cu@rGO/Nb2O5 Nanohybrid sensor platform

Alam, A., Gull, F., Shabbir, S., Younis, S., Batool, K., Iqbal, I., Javed, F., & Fatima, N. (2026) · Environmental Nanotechnology Monitoring & Management · doi:10.1016/j.enmm.2026.101170

Photoredox-Catalyzed Divergent Functionalizations of α-Trifluoromethyl Alkenes with Alcohols via Single-Electron Oxidation

Li, X. J., Yc, L., Xu, K.-J., Huang, Y.-J., Liu, J., Chen, X., Hong, X.-Y., & Fu, L. (2026) · Organic Letters · doi:10.1021/acs.orglett.6c02645

Magnesium-mediated reductive defluorinative cross-electrophile coupling of α-trifluoromethyl styrenes with chlorosilane enabling the synthesis of gem -difluoroallylhydrosilanes

Li, S., Hao, J., 雷婧, Jing, L., & Han, P. (2026) · Chemical Communications · doi:10.1039/d6cc03293a

Synthesis of Trifluoromethyl Pyrazolines via Tandem Cyclization of Nitrile Imines with Sulfur Ylides

Du, Y.-L., 万积秋, Wang, P., Li, J., Du, J., & He, Y. (2026) · Synthesis · doi:10.1055/a-2919-0357

Sulfone Activation Triggered by Iodide Anion for Photoinduced Fluoroalkylations

He, Y., Zhu, K., Hu, M., Ni, C., & Hu, J. (2026) · Angewandte Chemie · doi:10.1002/ange.8941062

Data-Efficient Distal Engineering of Fluorinase Using Zero-Shot Models

Harding-Larsen, D., Lax, B. M., Weingarten, C. K., Sako, A., Mazurenko, S., & Welner, D. H. (2026) · Chem & Bio Engineering · doi:10.1021/cbe.6c00028 · Cited by 1

Fluorescence spectroscopy of advanced materials for applications in environmental monitoring and diagnostics

Somaprakash, N., Shivananda, K. B., Rikhari, B., & Badiya, P. K. (2026) · Discover Chemistry. · doi:10.1007/s44371-026-00899-9

From Porphyrins to Versatile Photostable Bacteriochlorins: Triplet-State-Driven Design of Perfluorinated Photosensitizers

Barczyk, D., Warszyńska, M., Repetowski, P., Kuncewicz, J., & Dąbrowski, J. M. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6c01282

Scalable hydrogen-bonded organic framework-based membranes for efficient ultra-high PFOA adsorption

Gu, Z., Li, Y., Li, H., He, Y., Wang, W., Yao, Y., Hooley, R. J., Sessler, J. L., & Chi, X. (2026) · Chemical Science · doi:10.1039/d6sc03163c

Multidimensional interactions of living materials with biological entities

Shuqing, D., Liu, Y., Liu, Y., Tan, Y., Man, Y., Zhang, Z., Lv, Z., Lee, L. P., Chen, Q., & Liu, Z. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124565

Highly Efficient Removal of PFCAs by Metal‐Organic Frameworks via Chain‐Length‐Dependent Entrainment Co‐Adsorption Mechanism

Li, Z., Liu, Z., Zhou, T., Li, Q., Qin, H., Wu, M., Qiu, C., Yang, K., & Mao, S. (2026) · Advanced Functional Materials · doi:10.1002/adfm.77907

Three‐Component Defluorinative Annulation of Polyfluoroalkyl Tetralones, Amidines, and Cobalt‐Dionates: Synthesis of Fluoro‐Alkyl 4‐(furan‐2‐yl)quinazolines

Xiao, L.-T., Tang, M.-Y., Yang, Y.-Q., Ma, M., Mao, X.-X., Xu, H., Shen, Z., & Chu, X. (2026) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.70734

Synergistic multi-interaction in advanced PFAS sorbents: A review

Dong, W., Zhang, S., & Xia, X. (2026) · Journal of Water Process Engineering · doi:10.1016/j.jwpe.2026.110786

Boron complex dimers linked through the C3–C3′ positions of isoquinoline rings and their optical properties based on rigid structures

Nakano, T., Yamada, H., & Hamasaki, A. (2026) · Organic Chemistry Frontiers · doi:10.1039/d6qo00985a

One-pot sequential palladium-catalyzed defluorinative amination and Nazarov cyclization for the diastereoselective synthesis of α-fluorinated naphthocyclopentanones

Luo, Z., Wang, X., Tu, F., Liang, Q., Zhu, H., Xiong, Z., Hu, J., & Wu, J.-Q. (2026) · Chemical Communications · doi:10.1039/d6cc04470k

Accessing all Four Stereoisomers of β ‐Fluoroamines by Engineered Imine Reductase‐Mediated Dynamic Kinetic Reductive Amination

Xia, K., Zhang, J., Ding, Y., Sun, J., Xu, W., & Wu, Q. (2026) · Angewandte Chemie · doi:10.1002/ange.1344095

Fluorinated phosphate-modified micelles for bone-targeted oxygen delivery enabling enhanced photodynamic therapy of osteomyelitis

Li, R., Zhang, P., Zou, C., Pu, Y., Lu, X., Guo, Q., Jiang, Y., Yao, Y., Chen, Y., Yao, Y., et al. (2026) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2026.116158

Fluorination–defluorination chemistry as a toolbox for 2D materials design

Ahmad, Y., Gattin, C., Ighili, S., Cérémonie, L., Amarathunga, A. A. S., Hassan, S. H., Eraky, M. S., Karahan, H. E., Clavier, B., Bonnet, P., et al. (2026) · Journal of Fluorine Chemistry · doi:10.1016/j.jfluchem.2026.110628

Spatial adjacency engineering of hydrophilic moieties toward fluorinated segment for enhanced 19F magnetic resonance imaging

Ning, J., Wang, R., Ning, J., Li, Y., 熊小夭, Wang, L., & Xu, S. (2026) · Science China Materials · doi:10.1007/s40843-026-4442-4

Regenerable ion-exchange resin beads for continuous PFAS capture and regeneration for improved aqueous zinc batteries

Yang, Z., Wang, Y., Tan, X., Zhu, Y., Li, X., Dewapriya, P., Leung, L., Breske, S., Sworen, J. C., Brack, E. M., et al. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.182372

Advances in Trifluoromethoxylation Reactions

Ma, Z., & Tang, P. (2026) · Chinese Journal of Organic Chemistry · doi:10.6023/cjoc202604036

Research Progress on the Construction of N -Fluoroalkyl Compounds via Desulfurative Fluorination

Wang, J., Chen, X., Ma, L., & Yi, W. (2026) · Chinese Journal of Organic Chemistry · doi:10.6023/cjoc202606003

Progress on Fluorination and Fluoroalkylation Reactions of Aryl Sulfonium Salts

Fu, X., Wu, P., Song, J., Xin, X., Xu, W., & 张成潘 (2026) · Chinese Journal of Organic Chemistry · doi:10.6023/cjoc202605004

Visible-Light-Promoted Formal [4 + 3] Radical Annulation of Vinyldiazos: Access to Fluorinated Cyclohepta[ b ]indoles

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4-methyl-3-aminopyridine: A novel active blocker of voltage-gated potassium ion channels in the central nervous system

Rodríguez-Rangel, S., Coronado, O. G., Ortega, B. M., Sun, Y., El-Saadi, S., Brugarolas, P., & Sánchez‐Rodríguez, J. E. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.111216

Pd-catalyzed three-component coupling of gem -difluorocyclopropanes with α-diazoketones and H 2 O: merging two classic transformations in one pot for the synthesis of Z -fluorinated allylic esters

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Unexpected outcome in the reaction of tetrakis(dimethylamino)ethylene (TDAE) with bis(difluoromethyl)disulfide

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Unorthodox Applications of Diethylaminosulfur Trifluoride and its Analogs in Organic Synthesis

Zhang, C., Zhang, R., Niu, T., Su, Y., Ma, J., Gao, C., Lou, X., Wang, Y., Liu, J., Ma, Y., et al. (2026) · European Journal of Organic Chemistry · doi:10.1002/ejoc.70902

Controllable Single and Double C–F Bond Cleavage for Divergent Synthesis of Fluorinated Pyrroles and γ-Lactams

Wang, T., Feng, W.-Z., Zong, Y.-Y., Jin, X.-L., Yang, J., Zhang, J., Wu, L., & Liu, Q. (2026) · JACS Au · doi:10.1021/jacsau.6c01069

Engineering fluorinated nano–bio interfaces for enhanced intracellular delivery and colorectal cancer therapy

Ding, F., Cao, J., Huang, D., Hu, Y., Jiang, Z., Zhou, R., Zhao, L., & Chengzhu, W. U. (2026) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2026.142164

Photoredox‐Catalyzed Allenyl Radical Addition to SO ₂ for Allenyl Sulfones †

Xia, J., Jiao, K., Lv, Z., Chen, Y., Sun, J., Zhu, L., Xiong, T., Zhang, Q., & Zheng, G. (2026) · Chinese Journal of Chemistry · doi:10.1002/cjoc.70808

Photocatalyst‐Free Trifluoromethylation of Indolizines Through an Electron Donor–Acceptor Complex

Coutant, C., Koffi, K. J.-F., Lantigner, L., Retailleau, P., Herrero, C., Tran, C., Hamzé, A., & Piguel, S. (2026) · European Journal of Organic Chemistry · doi:10.1002/ejoc.70921

Fluorine and Health

Tressaud, A., & Haufe, G. (2008) · Elsevier eBooks · doi:10.1016/b978-0-444-53086-8.x0001-x · Cited by 22

Perfluoroalkylated Biomolecules for Medicinal Chemistry and Biological Studies

Brigaud, T., Crousse, B., & Lequeux, T. P. (2022) · Royal Society of Chemistry eBooks · doi:10.1039/9781839167591-00459

Fluorous-soluble chromophores for imaging and therapeutics in vivo

Lim, I. (2022) · eScholarship (California Digital Library)

The Role of Small Molecules Containing Fluorine Atoms in Medicine and Imaging Applications

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Fluorinated Protein and Peptide Materials for Biomedical Applications

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