Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 538

The DOI matches its Crossref record.

Protons and Hydroxide Ions in Aqueous Systems

Open access
Agmon, Noam, Bakker, Huib J., Campen, R. Kramer, Henchman, Richard H., Pohl, Peter, Roke, Sylvie, Thämer, Martin, Hassanali, Ali·2016·Chemical Reviews
DOI 10.1021/acs.chemrev.5b00736
Open this paper in CoChat — free account

Abstract

Understanding the structure and dynamics of water's constituent ions, proton and hydroxide, has been a subject of numerous experimental and theoretical studies over the last century. Besides their obvious importance in acid-base chemistry, these ions play an important role in numerous applications ranging from enzyme catalysis to environmental chemistry. Despite a long history of research, many fundamental issues regarding their properties continue to be an active area of research. Here, we provide a review of the experimental and theoretical advances made in the last several decades in understanding the structure, dynamics, and transport of the proton and hydroxide ions in different aqueous environments, ranging from water clusters to the bulk liquid and its interfaces with hydrophobic surfaces. The propensity of these ions to accumulate at hydrophobic surfaces has been a subject of intense debate, and we highlight the open issues and challenges in this area. Biological applications reviewed include proton transport along the hydration layer of various membranes and through channel proteins, problems that are at the core of cellular bioenergetics.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1021/acs.chemrev.5b00736

Cites

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 253

  1. 10.1021/cm950192a · DOI · Paper page
  2. 10.1016/j.bbabio.2005.12.001 · DOI · Paper page
  3. 10.1016/j.bbabio.2006.06.017 · DOI · Paper page
  4. 10.1021/cr900233f · DOI · Paper page
  5. 10.1021/ar200140h · DOI · Paper page
  6. 10.1021/acs.jpca.5b04355 · DOI
  7. 10.1021/ja01945a002 · doi:10.1021/ja01945a002
  8. 10.1021/ja01945a003 · doi:10.1021/ja01945a003
  9. 10.1021/ja01939a003 · doi:10.1021/ja01939a003
  10. 10.1002/andp.19494410129 · doi:10.1002/andp.19494410129
  11. Robinson R. A., 1959, Electrolyte Solutions
  12. 10.1063/1.1700960 · DOI · Paper page
  13. 10.1021/ja01076a008 · DOI
  14. 10.1063/1.451384 · DOI · Paper page
  15. Agmon N., 1996, J. Chim. Phys. Phys.-Chim. Biol., 93, 1714, 10.1051/jcp/1996931714 · DOI
  16. 10.1098/rspa.1958.0208 · DOI · Paper page
  17. 10.1002/anie.196400011 · DOI · Paper page
  18. 10.1002/anie.196904991 · DOI
  19. 10.1021/j150375a004 · DOI
  20. 10.1126/science.1113094 · DOI · Paper page
  21. 10.1021/j100372a014 · DOI · Paper page
  22. 10.1063/1.1834566 · doi:10.1063/1.1834566
  23. 10.1039/b924048a · DOI · Paper page
  24. 10.1039/c3cp50739d · DOI · Paper page
  25. 10.1103/PhysRevLett.55.2471 · DOI · Paper page
  26. 10.1063/1.2806992 · doi:10.1063/1.2806992
  27. 10.1146/annurev-physchem-040412-110122 · DOI · Paper page
  28. 10.1021/jp073912x · DOI · Paper page
  29. 10.1021/jp900737r · doi:10.1021/jp900737r
  30. 10.1063/1.2787596 · DOI · Paper page
  31. 10.1002/anie.200703555 · DOI
  32. 10.1002/anie.200702607 · doi:10.1002/anie.200702607
  33. 10.1063/1.3028211 · DOI
  34. 10.1021/ja401359t · DOI
  35. 10.1021/jp410446d · doi:10.1021/jp410446d
  36. 10.1039/c3cp54029d · doi:10.1039/c3cp54029d
  37. 10.1021/ct300293a · DOI
  38. 10.1016/j.cplett.2011.04.060 · doi:10.1016/j.cplett.2011.04.060
  39. 10.1021/ct100122s · doi:10.1021/ct100122s
  40. 10.1021/ja803535s · doi:10.1021/ja803535s
  41. 10.1126/science.1253788 · DOI
  42. 10.1021/ja3014727 · doi:10.1021/ja3014727
  43. 10.1073/pnas.1308560110 · DOI · Paper page
  44. 10.1002/cphc.201200695 · doi:10.1002/cphc.201200695
  45. 10.1021/jp507752e · DOI
  46. 10.1021/jz500970h · doi:10.1021/jz500970h
  47. 10.1021/acs.jpca.5b11062 · doi:10.1021/acs.jpca.5b11062
  48. 10.1038/nature00797 · DOI · Paper page
  49. 10.1021/ar200076s · DOI
  50. 10.1021/ar040207n · DOI · Paper page
  51. 10.1063/1.480954 · doi:10.1063/1.480954
  52. 10.1080/00268970110046312 · doi:10.1080/00268970110046312
  53. 10.1126/science.1080695 · DOI · Paper page
  54. 10.1016/j.chemphys.2012.03.016 · doi:10.1016/j.chemphys.2012.03.016
  55. 10.1021/jz502286b · DOI
  56. 10.1063/1.4941107 · doi:10.1063/1.4941107
  57. 10.1073/pnas.0901571106 · DOI
  58. 10.1063/1.4878490 · doi:10.1063/1.4878490
  59. 10.1016/0009-2614(95)00905-J · DOI · Paper page
  60. 10.1088/0953-8984/6/23A/010 · DOI
  61. 10.1073/pnas.1306642110 · DOI · Paper page
  62. 10.1002/bbpc.19050111003 · doi:10.1002/bbpc.19050111003
  63. von Grotthuss C. J. T., 1806, Ann. Chim., 58, 54
  64. Hückel E., 1928, Z. Elektrochem., 34, 546
  65. 10.1021/jp068960g · DOI · Paper page
  66. 10.1063/1.4801512 · doi:10.1063/1.4801512
  67. 10.1063/1.1749327 · DOI · Paper page
  68. 10.1021/jp804018y · DOI · Paper page
  69. 10.1063/1.469654 · DOI · Paper page
  70. 10.1103/PhysRevLett.103.238302 · DOI · Paper page
  71. 10.1021/ja00540a008 · DOI · Paper page
  72. 10.1063/1.479723 · DOI · Paper page
  73. 10.1021/ar0402098 · DOI · Paper page
  74. 10.1039/C5CP01035G · DOI
  75. 10.1063/1.1814973 · DOI · Paper page
  76. 10.1103/PhysRevLett.102.198303 · DOI
  77. 10.1073/pnas.1112486108 · DOI · Paper page
  78. 10.1126/science.1056991 · DOI · Paper page
  79. 10.1063/1.4905077 · DOI
  80. 10.1016/j.cplett.2014.03.034 · DOI
  81. 10.5012/bkcs.2006.27.8.1154 · doi:10.5012/bkcs.2006.27.8.1154
  82. 10.1021/jp901667c · doi:10.1021/jp901667c
  83. 10.1063/1.3691603 · doi:10.1063/1.3691603
  84. 10.1021/ct400863t · DOI · Paper page
  85. 10.1021/ct500079y · DOI · Paper page
  86. 10.1063/1.4825111 · DOI
  87. 10.1021/jp310300x · DOI
  88. 10.1021/ct5004115 · DOI · Paper page
  89. 10.1016/S0009-2614(00)00136-6 · DOI · Paper page
  90. 10.1063/1.2759484 · DOI · Paper page
  91. 10.1103/PhysRevLett.101.017801 · DOI · Paper page
  92. 10.1038/17579 · DOI · Paper page
  93. 10.1103/PhysRevLett.104.066102 · doi:10.1103/physrevlett.104.066102
  94. 10.1073/pnas.1016653108 · DOI · Paper page
  95. 10.1039/c3cp50218j · DOI
  96. 10.1063/1.1423327 · DOI · Paper page
  97. 10.1021/jz101536b · DOI
  98. 10.1038/nchem.1503 · DOI
  99. 10.1126/science.aab3908 · DOI · Paper page
  100. 10.1103/PhysRevLett.96.138305 · DOI
  101. 10.1021/jp108474p · doi:10.1021/jp108474p
  102. 10.1364/OL.35.001962 · DOI
  103. 10.1038/nchem.2465 · doi:10.1038/nchem.2465
  104. Förster Th., 1950, Z. Elektrochem., 54, 531
  105. Weller A., 1961, Prog. React. Kinet., 1, 187
  106. 10.1021/jp047465m · DOI · Paper page
  107. 10.1021/ar990109f · DOI · Paper page
  108. 10.1016/j.molstruc.2015.05.062 · doi:10.1016/j.molstruc.2015.05.062
  109. 10.1021/jp506011e · doi:10.1021/jp506011e
  110. 10.1063/1.454573 · DOI
  111. 10.1063/1.454572 · DOI
  112. 10.1063/1.447954 · doi:10.1063/1.447954
  113. 10.1103/PhysRevLett.68.3932 · doi:10.1103/physrevlett.68.3932
  114. 10.1021/jp2095856 · doi:10.1021/jp2095856
  115. 10.1021/acs.jpcb.5b02753 · DOI
  116. 10.1039/C5CP04548G · doi:10.1039/c5cp04548g
  117. 10.1039/C5CP05548B · DOI
  118. 10.1021/jp908126a · DOI
  119. 10.1126/science.1085762 · DOI · Paper page
  120. 10.1126/science.1117756 · DOI · Paper page
  121. 10.1002/anie.200603383 · DOI · Paper page
  122. 10.1021/ja069265p · doi:10.1021/ja069265p
  123. 10.1021/jp075663i · doi:10.1021/jp075663i
  124. 10.1021/jp9004778 · doi:10.1021/jp9004778
  125. 10.1002/cphc.200800406 · DOI
  126. 10.1016/S0009-2614(97)01245-1 · DOI
  127. 10.1021/jp000317l · DOI
  128. 10.1063/1.2889390 · DOI
  129. von Smoluchowski M., 1917, Z. Phys. Chem., 92, 129
  130. 10.1021/j100356a011 · DOI · Paper page
  131. 10.1063/1.3554654 · DOI
  132. 10.1021/jp507246e · DOI
  133. 10.1016/j.jcis.2014.02.003 · doi:10.1016/j.jcis.2014.02.003
  134. 10.1006/jcis.1996.0651 · DOI · Paper page
  135. 10.1016/j.cplett.2008.10.090 · doi:10.1016/j.cplett.2008.10.090
  136. Ottewill R. H., 1981, Zeta Potential in Colloid Science
  137. 10.1039/tf9383400300 · doi:10.1039/tf9383400300
  138. 10.1021/jp0445270 · DOI · Paper page
  139. 10.1021/jp906978v · doi:10.1021/jp906978v
  140. 10.1021/la950928i · DOI · Paper page
  141. 10.1016/j.cocis.2010.01.002 · DOI · Paper page
  142. 10.1039/b901806a · DOI
  143. 10.1039/B805266B · DOI · Paper page
  144. 10.1016/j.cplett.2009.09.010 · DOI
  145. 10.1039/c3cp51575c · doi:10.1039/c3cp51575c
  146. 10.1081/ASR-200038326 · DOI · Paper page
  147. 10.1021/jp044479j · DOI · Paper page
  148. 10.1016/j.cplett.2008.04.010 · DOI
  149. 10.1039/C4RA15401K · doi:10.1039/c4ra15401k
  150. 10.1021/ja063184b · DOI
  151. 10.1021/cr040361n · DOI · Paper page
  152. 10.1021/ja8021297 · doi:10.1021/ja8021297
  153. 10.1021/jp502890s · doi:10.1021/jp502890s
  154. 10.1016/j.cplett.2011.07.042 · doi:10.1016/j.cplett.2011.07.042
  155. 10.1126/science.1059514 · DOI · Paper page
  156. 10.1073/pnas.0901480106 · DOI
  157. 10.1016/j.cplett.2014.09.034 · doi:10.1016/j.cplett.2014.09.034
  158. 10.1039/b101673n · doi:10.1039/b101673n
  159. 10.1021/jp310732f · doi:10.1021/jp310732f
  160. 10.1063/1.4929905 · doi:10.1063/1.4929905
  161. 10.1021/ja202081x · DOI · Paper page
  162. 10.1016/j.elspec.2009.08.007 · DOI
  163. 10.1016/j.cplett.2009.04.053 · DOI
  164. 10.1039/c1cp20245f · doi:10.1039/c1cp20245f
  165. 10.1021/jz2003233 · DOI
  166. 10.1073/pnas.1209307109 · DOI
  167. 10.1038/nchem.1556 · DOI
  168. 10.1146/annurev-physchem-040412-110049 · DOI
  169. 10.1088/0953-8984/26/20/203101 · DOI
  170. 10.1063/1.1599274 · DOI
  171. 10.1021/jp110078s · doi:10.1021/jp110078s
  172. 10.1039/c3sc52862f · DOI
  173. 10.1021/jp046716o · DOI · Paper page
  174. 10.1021/jp805304j · DOI
  175. 10.1039/c3fd00087g · doi:10.1039/c3fd00087g
  176. 10.1021/jp0736185 · doi:10.1021/jp0736185
  177. 10.1021/jp209167w · DOI
  178. 10.1021/jacs.5b07232 · DOI
  179. 10.1073/pnas.0611285104 · DOI · Paper page
  180. 10.1021/ja077205t · DOI · Paper page
  181. 10.1021/jp809236c · doi:10.1021/jp809236c
  182. 10.1021/jp501854h · doi:10.1021/jp501854h
  183. 10.1039/b704491g · DOI · Paper page
  184. 10.1021/jp900290y · doi:10.1021/jp900290y
  185. 10.1016/j.cplett.2009.09.003 · DOI
  186. 10.1021/la960800g · doi:10.1021/la960800g
  187. 10.1002/anie.201204662 · doi:10.1002/anie.201204662
  188. 10.1016/0021-9797(80)90575-5 · doi:10.1016/0021-9797(80)90575-5
  189. 10.1021/jp2074545 · doi:10.1021/jp2074545
  190. Adamson A. W., 1997, Physical Chemistry of Surfaces
  191. 10.1080/00268976.2014.882521 · doi:10.1080/00268976.2014.882521
  192. 10.1103/PhysRevLett.114.118301 · doi:10.1103/physrevlett.114.118301
  193. 10.1021/jz2014852 · doi:10.1021/jz2014852
  194. 10.1063/1.4758457 · DOI
  195. 10.1021/jp061221f · doi:10.1021/jp061221f
  196. 10.1063/1.3455332 · doi:10.1063/1.3455332
  197. 10.1021/jp205842w · DOI
  198. 10.1021/jp205510q · doi:10.1021/jp205510q
  199. 10.1021/ja074811f · DOI
  200. 10.1021/jp808533y · DOI

200 of 253 shown

Cited by

See all 538

Metadata

Authors
Agmon, N., Bakker, H. J., Campen, R. K., Henchman, R. H., Pohl, P., Roke, S., Thämer, M., & Hassanali, A.
Venue
Chemical Reviews
Publisher
American Chemical Society (ACS)
Published
2016-06-17
Volume
116
Issue
13
Pages
7642-7672
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
DOI
10.1021/acs.chemrev.5b00736
OpenAlex
W2435408353
Cited by
538
References
0
FWCI
1.92
Type
journal article
Language
en
Open access
green
Funders
  • Vetenskapsrådet
  • Israel Science Foundation (766/12)
  • Austrian Science Fund (P25981)
  • Royal Swedish Academy of Sciences
  • Biotechnology and Biological Sciences Research Council (BB/K001558/1)
  • Department of Physics, Stockholm University

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Protons and Hydroxide Ions in Aqueous Systems. https://app.cochat.ai/papers/10.1021/acs.chemrev.5b00736
The paper
Agmon, N., Bakker, H. J., Campen, R. K., Henchman, R. H., Pohl, P., Roke, S., Thämer, M., & Hassanali, A. (2016). Protons and Hydroxide Ions in Aqueous Systems. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.5b00736

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.