Occurrence, Risk Implications, Prevention and Control of CIT in Monascus Cheese: A Review
Abstract
Monascus is a filamentous fungus that has been used in the food and pharmaceutical industries. When used as an auxiliary fermenting agent in the manufacturing of cheese, Monascus cheese is obtained. Citrinin (CIT) is a well-known hepatorenal toxin produced by Monascus that can harm the kidneys structurally and functionally and is frequently found in foods. However, CIT contamination in Monascus cheese is exacerbated by the metabolic ability of Monascus to product CIT, which is not lost during fermentation, and by the threat of contamination by Penicillium spp. that may be introduced during production and processing. Considering the safety of consumption and subsequent industrial development, the CIT contamination of Monascus cheese products needs to be addressed. This review aimed to examine its occurrence in Monascus cheese, risk implications, traditional control strategies, and new research advances in prevention and control to guide the application of biotechnology in the control of CIT contamination, providing more possibilities for the application of Monascus in the cheese industry.
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The 30-d ripening period adopted in this study is appropriate for soft goat cheese and captures the critical stage of microbial activity and flavor formation.
“Therefore, the 30-d ripening period adopted in this study can be considered appropriate for soft goat cheese and captures the critical stage of microbial activity and flavor formation (Zhang et al., 2024).”
From Impact of lactic acid bacteria coculture on the quality characteristics of goat cheese during ripening (2025) · cites this paper as Zhang et al., 2024
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Recent advances in the application of CRISPR/Cas-based gene editing technology in Filamentous Fungi
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- Authors
- Zhang, C., Cheng, Y., Qin, Y., Wang, C., Wang, H., Ablimit, A., Sun, Q., Dong, H., Wang, B., & Wang, C.
- Affiliations
- Beijing Technology and Business University (CN)
- Corresponding author
- Zhang, Chan
- Wang, Chengtao
- ORCID
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2024-04-16
- Volume
- 72
- Issue
- 17
- Pages
- 9567-9580
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W4394868888
- Cited by
- 13
- References
- 156
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 3
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (32072345, 32172185)
- Beijing Technology and Business University (BTBUYXTD202208)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
- Keywords
- citrinin, Monascus, mycotoxin contamination, hepatorenal toxicity, cheese fermentation, food safety
- MeSH terms
- Cheese, Citrinin, Fermentation, Food Contamination, Humans, Monascus
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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