The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles
Abstract
Oxygen heterocycles are the second most common type of heterocycles that appear as structural components of U.S. Food and Drug Administration (FDA) approved pharmaceuticals. Analysis of our database of drugs approved through 2017 reveals 311 distinct pharmaceuticals containing at least one oxygen heterocycle. Most prevalent among these are pyranoses, with furanoses, macrolactones, morpholines, and dioxolanes rounding off the top five. The main body of this Perspective is organized according to ring size, commencing with three- and four-membered rings and ending with macrocycles, polymers, and unusual oxygen-containing heterocycles. For each section, all oxygen heterocycle-containing drugs are presented along with a brief discussion about structural and drug application patterns.
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Oxadiazoles in Medicinal Chemistry
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Scott, K. A., Qureshi, M. H., Cox, P. B., Marshall, C. M., Bellaire, B. C., Wilcox, M., Stuart, B. A. R., & Njardarson, J. T. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c01502 · Cited by 56
Self-citationEssential Medicinal Chemistry of Essential Medicines
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Metadata
- Authors
- Delost, M. D., Smith, D. T., Anderson, B. J., & Njardarson, J. T.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2018-07-19
- Volume
- 61
- Issue
- 24
- Pages
- 10996-11020
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W2883457812
- Cited by
- 409
- References
- 67
- FWCI
- 18.29
- Type
- journal article
- Language
- en
- Open access
- closed
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