Cited by 179Nanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesUltrasound and Hyperthermia Applications

Sonodynamic Therapy (SDT) for Cancer Treatment: Advanced Sensitizers by Ultrasound Activation to Injury Tumor

Yan, Ping, Liu, Li-Han, Wang, Ping·2020·ACS Applied Bio Materials

Abstract

Because of its high tissue penetrative depth, high remote spatiotemporal selectivity, and noninvasive therapeutic features, sonodynamic therapy (SDT) has received much attention in recent years. In the SDT, a tumor-localizing sonosensitizing agent is activated by ultrasound and produces greatly reactive oxygen species (ROS) to kill tumor cells. Sonosensitizers, including some organic/inorganic compounds and micro/nanoscale sonosensitizers, are an important element in SDT. Herein, we will introduce the organic/inorganic sonosensitizers and advanced micro/nanosized sonosensitizers applied in SDT. At the same time, some perspectives and the future challenges of SDT will be discussed in this review.

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Crossref · 10.1021/acsabm.0c00156

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90 of 90 references verified0 citation errors · 0 not checkable

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Authors
Yan, P., Liu, L.-H., & Wang, P.
Affiliations
  • Third Affiliated Hospital of Southern Medical University (CN)
  • Southern Medical University (CN)
Corresponding author
  • Liu, Li-Han
  • Wang, Ping
Venue
ACS Applied Bio Materials
Published
2020-05-07
Volume
3
Issue
6
Pages
3456-3475
ISSN
2576-6422 (ISSN-L)
OpenAlex
W3021860117
Cited by
179
References
90
Citations by year
2026: 31 · 2025: 44 · 2024: 36 · 2023: 31 · 2022: 20 · 2021: 16 · 2020: 1
FWCI
5.35
Type
journal article
Language
en
Open access
closed
Locations
  • ACS Applied Bio Materials (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (51803087, 81672438)
  • Guangdong Province (2017A020215131)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
  • Physical Sciences › Engineering › Biomedical Engineering › Ultrasound and Hyperthermia Applications
Keywords
sonodynamic therapy, sonosensitizer, ultrasonic activation, reactive oxygen species, tumor cell killing, cancer therapy, non-invasive treatment

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