The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Prussian Blue Nanozyme with Multienzyme Activity Reduces Colitis in Mice
Abstract
The overproduction of reactive oxygen species (ROS) is central to the progression of inflammatory bowel disease (IBD), which may be the potential therapeutic target. Prussian blue (PB) nanoparticles with good biosafety can act as an artificial nanozyme, effectively scavenging ROS. To date, PB-based nanomaterials have not been developed and utilized for treatment of IBD. In this study, poly(vinylpyrrolidone)-modified Prussian blue (PPB) nanoparticles are constructed with good physiological stability and biosafety by a simple and efficient method. The prepared PPBs with capabilities of scavenging ROS and inhibiting proinflammatory cytokine significantly reduce colitis in mice without distinct side effects via intravenous administration. This report provides a demonstration of the protective effect of PB-based nanomedicine against IBD in living animals, offering hope and a potential alternative treatment option for patients suffering from IBD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Unravelling the pathogenesis of inflammatory bowel disease
Xavier, R. J., & Podolsky, D. K. (2007) · Nature · doi:10.1038/nature06005 · Cited by 4,364
Cited by
A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications
Liu, Q., Zhang, A., Wang, R., Zhang, Q., & Cui, D. (2021) · Nano-Micro Letters · doi:10.1007/s40820-021-00674-8 · Cited by 745
Specific Nanodrug for Diabetic Chronic Wounds Based on Antioxidase-Mimicking MOF-818 Nanozymes
Chao, D., Dong, Q., Yu, Z., Qi, D., Li, M., Xu, L., Liu, L., Fang, Y., & Dong, S. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c09663 · Cited by 317
Metal–Organic‐Framework‐Engineered Enzyme‐Mimetic Catalysts
Ma, L., Jiang, F., Fan, X., Wang, L., He, C., Zhou, M., Li, S., Luo, H., Cheng, C., & Qiu, L. (2020) · Advanced Materials · doi:10.1002/adma.202003065 · Cited by 298
Metadata
- Authors
- Zhao, J., Cai, X., Gao, W., Zhang, L., Zou, D., Zheng, Y., Li, Z., & Chen, H.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2018-07-20
- Volume
- 10
- Issue
- 31
- Pages
- 26108-26117
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2884855541
- Cited by
- 243
- References
- 1
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Prussian Blue Nanozyme with Multienzyme Activity Reduces Colitis in Mice. https://app.cochat.ai/papers/10.1021/acsami.8b10345
- The paper
- Zhao, J., Cai, X., Gao, W., Zhang, L., Zou, D., Zheng, Y., Li, Z., & Chen, H. (2018). Prussian Blue Nanozyme with Multienzyme Activity Reduces Colitis in Mice. ACS Applied Materials & Interfaces. https://doi.org/10.1021/acsami.8b10345
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
