The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Multienzyme Cascade Reactions—Status and Recent Advances
Abstract
Cascade reactions catalyzed by multienzymatic systems have strongly moved into the focus of researchers in the field of biocatalysis because of their unique potential for the environmentally benign production of chemicals and materials. Inspired by Nature’s ingenuity, considerable progress has been made in recent years to develop multistep reactions that combine the synthetic power of several enzymes in one pot. In addition, the combination of this biocatalytic power with the potential of chemical reactions, man-made transition-metal catalysts, and metalloenzymes has even further widened the repertoire of possible catalyzed reaction schemes. In this Review, we describe recent developments with respect to major challenges and solutions in the field of multienzyme cascade reactions, covering recent concurrent and sequential approaches with three or more enzymes in linear sequence as well as chemo-enzymatic reactions that combine a chemical step with at least two different enzymes over the last six years.
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Cites
A synthetic pathway for the fixation of carbon dioxide in vitro
Schwander, T., Schada von Borzyskowski, L., Burgener, S., Cortina, N. S., & Erb, T. J. (2016) · Science · doi:10.1126/science.aah5237 · Cited by 690
Substrate channelling as an approach to cascade reactions
Wheeldon, I., Minteer, S. D., Banta, S., Barton, S. C., Atanassov, P., & Sigman, M. (2016) · Nature Chemistry · doi:10.1038/nchem.2459 · Cited by 680
Artificial Biocatalytic Linear Cascades for Preparation of Organic Molecules
Schrittwieser, J. H., Velikogne, S., Hall, M., & Kroutil, W. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00033 · Cited by 634
Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathways
France, S. P., Hepworth, L. J., Turner, N. J., & Flitsch, S. L. (2017) · ACS Catalysis · doi:10.1021/acscatal.6b02979 · Cited by 427
Cell‐free metabolic engineering: Biomanufacturing beyond the cell
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Cascade catalysis – strategies and challenges en route to preparative synthetic biology
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Cell‐Free Metabolic Engineering: Production of Chemicals by Minimized Reaction Cascades
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Multistep One-Pot Reactions Combining Biocatalysts and Chemical Catalysts for Asymmetric Synthesis
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Metadata
- Authors
- Sperl, J. M., & Sieber, V.
- Venue
- ACS Catalysis
- Publisher
- American Chemical Society (ACS)
- Published
- 2018-02-14
- Volume
- 8
- Issue
- 3
- Pages
- 2385-2396
- ISSN
- 2155-5435 (ISSN-L)
- OpenAlex
- W2784547996
- Cited by
- 363
- References
- 51
- FWCI
- 13.26
- Type
- journal article
- Language
- en
- Open access
- closed
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