NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

Dixon, Andrew S., Schwinn, Marie K., Hall, Mary P., Zimmerman, Kris, Otto, Paul, Lubben, Thomas H., Butler, Braeden L., Binkowski, Brock F. +6 more·2016·ACS Chemical Biology

Cited by (1,002)

Items 101–200 of 1,002

  1. Glow-in-the-Dark Infectious Disease Diagnostics Using CRISPR-Cas9-Based Split Luciferase Complementation
    Harmen J. van der Veer, Eva A. van Aalen, Claire M. S. Michielsen, Eva T. L. Hanckmann, Jeroen Deckers, Marcel M. G. J. van Borren, Jacky Flipse, Anne J. M. Loonen, Joost P. H. Schoeber, Maarten Merkx · 2023 · ACS Central Science
  2. Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors
    Kazem Nouri, Taha Azad, Min Ling, Helena J. Janse van Rensburg, Alexander Pipchuk, He Shen, Yawei Hao, Jianmin Zhang, Xiaolong Yang · 2019 · Cancers
  3. Disconnect between signalling potency and in vivo efficacy of pharmacokinetically optimised biased glucagon-like peptide-1 receptor agonists
    Maria Lucey, Philip Pickford, Stavroula Bitsi, JAMES S. MINNION, Jan Ungewiss, Katja Schoeneberg, Guy A. Rutter, Stephen Robert Bloom, Alejandra Tomás, Ben J. Jones · 2020 · Molecular Metabolism
  4. Multiplexed bioluminescence microscopy via phasor analysis
    Zi W. Yao, Caroline K. Brennan, Lorenzo Scipioni, Hongtao Chen, Kevin K. Ng, Giulia Tedeschi, Kshitij Parag‐Sharma, Antonio L. Amelio, Enrico Gratton, Michelle A. Digman et al. · 2022 · Nature Methods
  5. An improved pathway for autonomous bioluminescence imaging in eukaryotes
    Ekaterina S. Shakhova, Tatiana A. Karataeva, Nadezhda M. Markina, Tatiana Yu Mitiouchkina, Kseniia A. Palkina, Maxim M. Perfilov, Monika G. Wood, Trish T. Hoang, Mary P. Hall, Liliia I. Fakhranurova et al. · 2024 · Nature Methods
  6. Advancing endosomal escape of polymeric nanoparticles: towards improved intracellular delivery
    Yufu Wang, Vajini Ukwattage, Yijun Xiong, Georgina K. Such · 2025 · Materials Horizons
  7. A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor
    Wen Ce Sun, Li-Nan Chen, Qingtong Zhou, Lihua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dandan Shen, Fenghui Zhao, Fulai Zhou et al. · 2020 · Cell Research
  8. Molecular basis of ligand recognition and activation of human V2 vasopressin receptor
    Fulai Zhou, Chenyu Ye, Xiaomin Ma, Wanchao Yin, Tristan Ian Croll, Qingtong Zhou, Xinheng He, Xiaokang Zhang, Dehua Yang, Peiyi Wang et al. · 2021 · Cell Research
  9. Cholesterol determines the cytosolic entry and seeded aggregation of tau
    Benjamin J. Tuck, Lauren V. C. Miller, Taxiarchis Katsinelos, Annabel E. Smith, Emma Louise Wilson, Sophie Keeling, Shi Cheng, Marina J. Vaysburd, Claire Knox, Lucy Tredgett et al. · 2022 · Cell Reports
  10. Screening for molecular glues – Challenges and opportunities
    Geoffrey A. Holdgate, Catherine Bardelle, Sophia K. Berry, Alice Lanne, Maria Emanuela Cuomo · 2023 · SLAS DISCOVERY
  11. Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
    Paola Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri, Ludovica Lospinoso Severini, Romina Alfonsi, Daniela Mazzà, Mariangela Siler, Sonia Coni, Agnese Pò et al. · 2018 · Nature Communications
  12. Conformational signatures in β-arrestin2 reveal natural biased agonism at a G-protein-coupled receptor
    Arfaxad Reyes‐Alcaraz, Yoo-Na Lee, Seongsik Yun, Jong‐Ik Hwang, Jae Young Seong · 2018 · Communications Biology
  13. Super-rapid quantitation of the production of HIV-1 harboring a luminescent peptide tag
    Seiya Ozono, Yanzhao Zhang, Minoru Tobiume, Satoshi Kishigami, Kenzo Tokunaga · 2020 · Journal of Biological Chemistry
  14. Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform
    Vasudevan, Lakshmi, Vandeputte, Marthe, Deventer, Marie, Wouters, Elise, Cannaert, Annelies, Stove, Christophe P. · 2020 · Biochemical Pharmacology
  15. Ratiometric Bioluminescent Sensor Proteins Based on Intramolecular Split Luciferase Complementation
    Yan Ni, Remco Arts, Maarten Merkx · 2018 · ACS Sensors
  16. K-RasG12D Has a Potential Allosteric Small Molecule Binding Site
    Huizhong Feng, Yan Zhang, Pieter H. Bos, Jennifer M. Chambers, Marcel M. Dupont, Brent R. Stockwell · 2019 · Biochemistry
  17. Key phosphorylation sites in GPCRs orchestrate the contribution of β‐Arrestin 1 in ERK1/2 activation
    Mithu Baidya, Punita Kumari, Hemlata Dwivedi‐Agnihotri, Shubhi Pandey, Madhu Chaturvedi, Tomasz Maciej Stępniewski, Kouki Kawakami, Yubo Cao, Stéphane A. Laporte, Jana Selent et al. · 2020 · EMBO Reports
  18. Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays
    Eline Pottie, Peter Dedecker, Christophe Pol Stove · 2020 · Biochemical Pharmacology
  19. A NanoLuc luciferase‐based assay enabling the real‐time analysis of protein secretion and injection by bacterial type III secretion systems
    Sibel Westerhausen, Melanie Nowak, Claudia E. Torres‐Vargas, Ursula Bilitewski, Erwin Bohn, Iwan Grin, Samuel Wagner · 2020 · Molecular Microbiology
  20. Molecular mechanisms of fentanyl mediated β-arrestin biased signaling
    Parker W. de Waal, Jingjing Shi, Erli You, Xiaoxi Wang, Karsten Melcher, Yi Jiang, H. Eric Xu, Bradley M. Dickson · 2020 · PLoS Computational Biology
  21. Advances in peptide-mediated cytosolic delivery of proteins
    Macarena Sánchez‐Navarro · 2021 · Advanced Drug Delivery Reviews
  22. Recent progress in assays for GPCR drug discovery
    Shimeng Guo, Tingting Zhao, Ying Yun, Xin Xie · 2022 · American Journal of Physiology-Cell Physiology
  23. How Carvedilol activates β2-adrenoceptors
    Tobias Benkel, Mirjam Zimmermann, Julian Zeiner, Sergi Bravo, Nicole Merten, Victor Lim, Edda S. F. Matthees, Julia Drube, Elke Miess, Daniela Malan et al. · 2022 · Nature Communications
  24. Homogeneous Noncompetitive Luminescent Immunodetection of Small Molecules by Ternary Protein Fragment Complementation
    Yuki Ohmuro‐Matsuyama, Hiroshi Ueda · 2018 · Analytical Chemistry
  25. A revised model of TRAIL‐R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis
    Luke M. Humphreys, Jennifer P. Fox, Catherine A. Higgins, Joanna Majkut, Tamas Sessler, Kirsty M. McLaughlin, Christopher K. McCann, Jamie Z. Roberts, Nyree Crawford, Simon S. McDade et al. · 2020 · EMBO Reports
  26. Autophagy-competent mitochondrial translation elongation factor TUFM inhibits caspase-8-mediated apoptosis
    Chang‐Yong Choi, Mai Tram Vo, John Nicholas, Young Bong Choi · 2021 · Cell Death and Differentiation
  27. Robust LC3B lipidation analysis by precisely adjusting autophagic flux
    Martina P. Liebl, Sarah C. Meister, Lisa Frey, Kristina Hendrich, Anja Klemmer, Bettina Wohlfart, Christopher Untucht, Judith Nuber, Christian Pohl, Viktor Lakics · 2022 · Scientific Reports
  28. Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor
    Jie Heng, Yunfei Hu, Guillermo Pérez‐Hernández, Asuka Inoue, Jiawei Zhao, Xiuyan Ma, Xiaoou Sun, Kouki Kawakami, Tatsuya Ikuta, Jienv Ding et al. · 2023 · Nature Communications
  29. Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief
    Alan Hégron, Chloe J. Peach, Raquel Tonello, Philipp Seemann, Shavonne L. Teng, Rocco Latorre, Harald Huebner, Dorothée Weikert, Jeanette M. J. Rientjes, Nicholas A. Veldhuis et al. · 2023 · Proceedings of the National Academy of Sciences
  30. Application of a novel HiBiT peptide tag for monitoring ATF4 protein expression in Neuro2a cells
    Kentaro Oh‐hashi, Eri Furuta, Keito Fujimura, Yoko Hirata · 2017 · Biochemistry and Biophysics Reports
  31. Allosteric small molecule modulators of nuclear receptors
    Femke A. Meijer, Iris A. Leijten-van de Gevel, Rens M. J. M. de Vries, Luc Brunsveld · 2019 · Molecular and Cellular Endocrinology
  32. Genetically Encoded Fluorescence/Bioluminescence Bimodal Indicators for Ca2+ Imaging
    Israt Farhana, Md. Nadim Hossain, Kazushi Suzuki, Tomoki Matsuda, Takeharu Nagai · 2019 · ACS Sensors
  33. Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CLpro Inhibitors
    Jonathan M. O. Rawson, Alice A. Duchon, Olga A. Nikolaitchik, Vinay K. Pathak, Wei-Shau Hu · 2021 · Viruses
  34. Acidosis-induced activation of anion channel SLAH3 in the flooding-related stress response of Arabidopsis
    Julian Lehmann, Morten Egevang Jørgensen, Stefanie Fratz, Heike M. Müller, Jana Kusch, Sönke Helmut Scherzer, Carlos Navarro‐Retamal, Dominik Mayer, Jennifer Böhm, Kai Robert Konrad et al. · 2021 · Current Biology
  35. Signalling, trafficking and glucoregulatory properties of glucagon‐like peptide‐1 receptor agonists exendin‐4 and lixisenatide
    Philip Pickford, Maria Lucey, Zijian Fang, Stavroula Bitsi, Jorge Bernardino de la Serna, Johannes Broichhagen, David J. Hodson, JAMES S. MINNION, Guy A. Rutter, Stephen Robert Bloom et al. · 2020 · British Journal of Pharmacology
  36. Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly
    Christopher F. Bennett, Katherine E. O’Malley, Elizabeth A. Perry, Eduardo Balsa, Pedro Latorre‐Muro, Christopher L. Riley, Chi Luo, Mark P. Jedrychowski, Steven P. Gygi, Pere Puigserver · 2021 · Nature Chemical Biology
  37. Palmitoylation licenses RIPK1 kinase activity and cytotoxicity in the TNF pathway
    Na Zhang, Jianping Liu, Rui Guo, Lingjie Yan, Yuanxin Yang, Shilin Chen, Mengmeng Zhang, Bing Shan, Wanjin Li, Jinyang Gu et al. · 2024 · Molecular Cell
  38. A homogeneous bioluminescent immunoassay to probe cellular signaling pathway regulation
    Byounghoon Hwang, Laurie Engel, Said A. Goueli, Hicham Zegzouti · 2020 · Communications Biology
  39. Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays
    Eline Pottie, Dilip K. Tosh, Zhan‐Guo Gao, Kenneth A. Jacobson, Christophe Pol Stove · 2020 · Biochemical Pharmacology
  40. Target Validation Using PROTACs: Applying the Four Pillars Framework
    Radosław P. Nowak, Lyn H. Jones · 2020 · SLAS DISCOVERY
  41. CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6
    Andy Chevigné, Bassam Janji, Max Meyrath, Nathan Reynders, Giulia D’Uonnolo, Tomasz Uchański, Malina Xiao, Guy Berchem, Markus W. Ollert, Yong‐Jun Kwon et al. · 2021 · Cancers
  42. trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo
    Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, Kristie L. Connolly, Pooja Srinivas, Matthew C. Torhan, John N. Alumasa, Mynthia Cabrera, Divya Hosangadi, Jay S. Barbor et al. · 2021 · Nature Communications
  43. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties
    Katarzyna Szczepańska, Sabina Podlewska, Maria Dichiara, Davide Gentile, Vincenzo Patamia, Niklas Rosier, Denise Mönnich, M. Carmen Ruiz‐Cantero, Tadeusz P. Karcz, Dorota Łażewska et al. · 2021 · ACS Chemical Neuroscience
  44. A fluorogenic chemically induced dimerization technology for controlling, imaging and sensing protein proximity
    Bottone, Sara, Joliot, Octave, Cakil, Zeyneb Vildan, El Hajji, Lina, Rakotoarison, Louise-Marie, Boncompain, Gaelle, Perez, Franck, Gautier, Arnaud · 2023 · Nature Methods
  45. Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells
    Rachid Safi, Suzanne E. Wardell, Paige Watkinson, Xiaodi Qin, Marissa Lee, Sunghee Park, Taylor Krebs, Emma L. Dolan, Adam Blattler, Toshiya Tsuji et al. · 2024 · Nature Communications
  46. Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assay
    Michihito Sasaki, Paulina Duhita Anindita, Wallaya Phongphaew, Michael J. Carr, Shintaro Kobayashi, Yasuko Orba, Hirofumi Sawa · 2017 · Virus Research
  47. Development of a novel homogeneous immunoassay using the engineered luminescent enzyme NanoLuc for the quantification of the mycotoxin fumonisin B1
    Tawfiq S. Alsulami, Nidhi Nath, Rod Flemming, Hui Wang, Wenhui Zhou, Jae‐Hyuk Yu · 2020 · Biosensors and Bioelectronics
  48. Photocleavable proteins that undergo fast and efficient dissociation
    Xiaocen Lu, Yurong Wen, Shuce Zhang, Wei Zhang, Yilun Chen, Yi Shen, M. Joanne Lemieux, Robert E. Campbell · 2021 · Chemical Science
  49. Biophysical and Computational Approaches to Study Ternary Complexes: A ‘Cooperative Relationship’ to Rationalize Targeted Protein Degradation
    Jake A. Ward, Carles Perez‐Lopez, Cristina Mayor‐Ruiz · 2023 · ChemBioChem
  50. CDK Family PROTAC Profiling Reveals Distinct Kinetic Responses and Cell Cycle–Dependent Degradation of CDK2
    Kristin M. Riching, Marie K. Schwinn, James D. Vasta, Matthew B. Robers, Thomas Machleidt, Marjeta Urh, Danette L. Daniels · 2020 · SLAS DISCOVERY
  51. The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models
    Scott P Davies, Courtney J. Mycroft‐West, Isabel Pagani, Harriet J. Hill, Yen‐Hsi Chen, Richard Torbjörn Gustav Karlsson, Ieva Bagdonaite, Scott E. Guimond, Zania Stamataki, Marcelo Andrade de Lima et al. · 2021 · Frontiers in Pharmacology
  52. Resolvin E3 attenuates allergic airway inflammation via the interleukin‐23‐interleukin‐17A pathway
    Makiko Sato, Haruka Aoki‐Saito, Hayato Fukuda, Hiroyuki Ikeda, Yasuhiko Koga, Masakiyo Yatomi, Hiroaki Tsurumaki, Toshitaka Maeno, Tsugumichi Saito, Takashi Nakakura et al. · 2019 · The FASEB Journal
  53. Mice expressing fluorescent PAR 2 reveal that endocytosis mediates colonic inflammation and pain
    Rocco Latorre, Alan Hégron, Chloe J. Peach, Shavonne L. Teng, Raquel Tonello, Jeffri S. Retamal, Rafael Klein-Cloud, Diana D. Bok, Dane D. Jensen, Lena Gottesman-Katz et al. · 2022 · Proceedings of the National Academy of Sciences
  54. Exploiting NanoLuc luciferase for smartphone-based bioluminescence cell biosensor for (anti)-inflammatory activity and toxicity
    Luca Cevenini, Maria Maddalena Calabretta, Antonia Lopreside, Giuseppe Tarantino, Annalisa Tassoni, Maura Ferri, Aldo Roda, Elisa Michelini · 2016 · Analytical and Bioanalytical Chemistry
  55. Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists
    Martyna Szpakowska, Max Meyrath, Nathan Reynders, Manuel Counson, Julien Hanson, Jan Steyaert, Andy Chevigné · 2018 · Biochemical Pharmacology
  56. Function of BriC peptide in the pneumococcal competence and virulence portfolio
    Surya D. Aggarwal, Rory A. Eutsey, Jacob A. West-Roberts, Arnau Domenech, Wenjie Xu, Iman Tajer Abdullah, Aaron P. Mitchell, Jan‐Willem Veening, Hasan Yeşilkaya, Natalia Luisa Hiller · 2018 · PLoS Pathogens
  57. Engineering Protein Switches for Rapid Diagnostic Tests
    Hope Adamson, Lars J. C. Jeuken · 2020 · ACS Sensors
  58. Intracellular Ionic Strength Sensing Using NanoLuc
    Tausif Altamash, Wesam S. Ahmed, Saad Rasool, Kabir Hassan Biswas · 2021 · International Journal of Molecular Sciences
  59. GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models
    Robert J. Torphy, Yi Sun, Ronggui Lin, Alayna K. Caffrey-Carr, Yuki Fujiwara, Felix Ho, Emily N. Miller, Martin D. McCarter, Traci Renae Lyons, Richard David Schulick et al. · 2022 · Nature Communications
  60. Technologies for Frugal and Sensitive Point-of-Care Immunoassays
    David Kinnamon, Jacob T. Heggestad, Jason Liu, Ashutosh Chilkoti · 2022 · Annual Review of Analytical Chemistry
  61. Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition
    Rebecca M. Haley, Alexander Chan, Margaret M. Billingsley, Ningqiang Gong, Marshall Scott Padilla, Emily H. Kim, Hejia Henry Wang, Dingzi Yin, Kirk J. Wangensteen, Andrew Tsourkas et al. · 2023 · ACS Applied Materials & Interfaces
  62. A High-Resolution Luminescent Assay for Rapid and Continuous Monitoring of Protein Translocation across Biological Membranes
    Gonçalo C. Pereira, William John Allen, Daniel W. Watkins, Lisa Buddrus, Dylan P. Noone, Xia Liu, Andrew P. Richardson, Agnieszka Chacińska, Ian R. Collinson · 2019 · Journal of Molecular Biology
  63. Discovery and Characterization of 1H-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy
    Junjie Yang, Weiwei Yu, Longlong Hu, Wenjuan Liu, Xian-Hua Lin, Wei Wang, Qiansen Zhang, Peili Wang, Shuowen Tang, Xin Wang et al. · 2019 · Journal of Medicinal Chemistry
  64. Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells
    Zijian Fang, Shiqian Chen, Yusman Manchanda, Stavroula Bitsi, Philip Pickford, Alessia David, Maria M. Shchepinova, Ivan Reis Correa Junior, David J. Hodson, Johannes Broichhagen et al. · 2020 · International Journal of Molecular Sciences
  65. Engineering with NanoLuc: a playground for the development of bioluminescent protein switches and sensors
    Lieuwe Biewenga, Bas J. H. M. Rosier, Maarten Merkx · 2020 · Biochemical Society Transactions
  66. Tools for computational design and high-throughput screening of therapeutic enzymes
    Michal Vasina, Jan Velecký, Joan Planas-Iglesias, Sérgio M. Marques, Jana Skarupova, Jiřı́ Damborský, David Bednář, Stanislav Mazurenko, Zbyněk Prokop · 2022 · Advanced Drug Delivery Reviews
  67. Nanobody/NanoBiT system-mediated bioluminescence immunosensor for one-step homogeneous detection of trace ochratoxin A in food
    Xiaoxia Xie, Zhenyun He, Chaoshuang Qu, Zhichang Sun, Hongmei Cao, Xing Liu · 2022 · Journal of Hazardous Materials
  68. Engineered Amber-Emitting Nano Luciferase and Its Use for Immunobioluminescence Imaging In Vivo
    Ying Xiong, Yiyu Zhang, Zefan Li, Md Shamim Reza, Xinyu Li, Xiaodong Tian, Hui‐wang Ai · 2022 · Journal of the American Chemical Society
  69. Cryo-EM advances in GPCR structure determination
    Wataru Shihoya, Aika Iwama, Fumiya K. Sano, Osamu Nureki · 2024 · The Journal of Biochemistry
  70. Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1
    Timothy A. Vickers, Meghdad Rahdar, Thazha P. Prakash, Stanley T. Crooke · 2019 · Nucleic Acids Research
  71. Novel reporters of mitochondria‐associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis
    Shohei Sakai, Seiji Watanabe, Okiru Komine, Akira Sobue, Koji Yamanaka · 2021 · The FASEB Journal
  72. Small-molecule binding and sensing with a designed protein family
    2026
  73. GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway
    Nick Hoppe, Simone Harrison, Sun‐Hee Hwang, Zi-Wei Chen, Masha Karelina, Ishan Deshpande, Carl‐Mikael Suomivuori, Vivek Reddy Palicharla, Samuel P. Berry, Philipp Tschaikner et al. · 2024 · Nature Structural & Molecular Biology
  74. Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art
    Elise Wouters, Lakshmi Vasudevan, René A. J. Crans, Deepak Kumar Saini, Christophe Pol Stove · 2019 · International Journal of Molecular Sciences
  75. A kinome‐wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion
    Kazem Nouri, Taha Azad, Elizabeth D. Lightbody, Prem Khanal, Christopher J.B. Nicol, Xiaolong Yang · 2019 · The FASEB Journal
  76. The SecA motor generates mechanical force during protein translocation
    Riti Gupta, Dmitri D. Toptygin, Christian Kaiser · 2020 · Nature Communications
  77. Neuropilin-1 inhibition suppresses nerve growth factor signaling and nociception in pain models
    Chloe J. Peach, Raquel Tonello, Elisa Damo, Kimberly Gómez, Aida Calderón‐Rivera, Renato Bruni, Harsh Bansia, Laura Maile, Ana-Maria Manu, Hyunggu Hahn et al. · 2024 · Journal of Clinical Investigation
  78. Cytoskeleton-functionalized synthetic cells with life-like mechanical features and regulated membrane dynamicity
    Sebastian Novosedlik, Felix Reichel, Thijs W. van Veldhuisen, Yudong Li, Hanglong Wu, Henk M. Janssen, Jochen R. Guck, Jan C. M. van Hest · 2025 · Nature Chemistry
  79. NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization
    Mark Soave, Barrie Kellam, Jeanette Woolard, Stephen J. Briddon, Stephen John Hill · 2019 · SLAS DISCOVERY
  80. Spatiotemporal functional assembly of split protein pairs through a light-activated SpyLigation
    Emily R. Ruskowitz, Brizzia G. Munoz‐Robles, Alder C. Strange, Carson H. Butcher, Sebastian Kurniawan, Jeremy R. Filteau, Cole A. DeForest · 2023 · Nature Chemistry
  81. Start codon-associated ribosomal frameshifting mediates nutrient stress adaptation
    Yuanhui Mao, Longfei Jia, Leiming Dong, Xin Erica Shu, Shu‐Bing Qian · 2023 · Nature Structural & Molecular Biology
  82. Illuminating the mechanism and allosteric behavior of NanoLuc luciferase
    Michal Nemergut, Daniel Pluskal, Jana Horackova, Tereza Sustrova, Jan Tulis, Tomáš Bárta, Racha Baatallah, Glwadys Gagnot, Veronika Novakova, Marika Majerova et al. · 2023 · Nature Communications
  83. A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays
    Andrew S. Dixon, Sun Jin Kim, Brett K. Baumgartner, Sylvia Krippner, Shawn C. Owen · 2017 · Scientific Reports
  84. Multiple GPCR Functional Assays Based on Resonance Energy Transfer Sensors
    Yiwei Zhou, Jiyong Meng, Chanjuan Xu, Jianfeng Liu · 2021 · Frontiers in Cell and Developmental Biology
  85. Cross-Species Tropism and Antigenic Landscapes of Circulating SARS-CoV-2 Variants
    Yali Zhang, Min Wei, Yangtao Wu, Juan Wang, Yuting Hong, Yang Huang, Lunzhi Yuan, Jian Ma, Kai Wang, Shaojuan Wang et al. · 2021 · Cell Reports
  86. Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement
    Tino W. Sanchez, Michael H. Ronzetti, Ashley E. Owens, Maria B. Antony, Ty C. Voss, Eric Wallgren, Daniel C. Talley, Krishna Balakrishnan, Sebastian Leyes Porello, Ganesha Rai et al. · 2022 · ACS Chemical Biology
  87. Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
    Justin A. Peruzzi, Jan Steinkühler, Timothy Q. Vu, Taylor F. Gunnels, Vivian T. Hu, Peilong Lu, David A. Baker, Neha P. Kamat · 2024 · Nature Communications
  88. Development of a Split Esterase for Protein–Protein Interaction-Dependent Small-Molecule Activation
    Krysten A. Jones, Kaitlin Kentala, Michael W. Beck, Weiwei An, Alexander R. Lippert, Jared C. Lewis, Bryan C. Dickinson · 2019 · ACS Central Science
  89. The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists
    Fang, Zijian, Chen, Shiqian, Pickford, Philip, Broichhagen, Johannes, Hodson, David J., Corrêa, Ivan R., Kumar, Sunil, Görlitz, Frederik, Dunsby, Chris, French, Paul M. W. et al. · 2020 · ACS Pharmacology & Translational Science
  90. Activation of the Orphan G Protein–Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment
    Nadine Dupuis, Céline Laschet, Delphine Franssen, Martyna Szpakowska, Julie Gilissen, Pierre Geubelle, Arvind Soni, Anne‐Simone Parent, Bernard Pirotte, Andy Chevigné et al. · 2017 · Molecular Pharmacology
  91. A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome
    Kohei Omachi, Misato Kamura, Keisuke Teramoto, Haruka Kojima, Tsubasa Yokota, Shota Kaseda, Jun Kuwazuru, Ryosuke Fukuda, Kosuke Koyama, Shingo Matsuyama et al. · 2018 · Cell chemical biology
  92. Efficient generation of epitope-targeted antibodies with Germinal
    Luis Santiago Mille, Claudia L. Driscoll, John N. Wang, Haoyu Dai, Talal Widatalla, Jim L. Zhang, Xiaowei Zhang, Bing Rao, Liang Feng, Brian Hie et al. · 2026 · Nature Biotechnology
  93. Rewiring of RSK-PDZ interactions by linear motif phosphorylation
    Gergő Gógl, Beáta Biri‐Kovács, Fabien Durbesson, Pau Jané, Yves Nominé, Camille Kostmann, Viktória Bilics, Márton A. Simon, Attila Reményi, Renaud Vincentelli et al. · 2018 · Journal of Molecular Biology
  94. Split Nano luciferase complementation for probing protein‐protein interactions in plant cells
    Fengzhu Wang, Nannan Zhang, Yanjun Guo, Ben‐Qiang Gong, Jianfeng Li · 2019 · Journal of Integrative Plant Biology
  95. Acylation of the Incretin Peptide Exendin-4 Directly Impacts Glucagon-Like Peptide-1 Receptor Signaling and Trafficking
    Maria Lucey, Tanyel Ashik, Amaara Marzook, Yifan Wang, Joëlle Goulding, Atsuro Oishi, Johannes Broichhagen, David J. Hodson, JAMES S. MINNION, Yuval Elani et al. · 2021 · Molecular Pharmacology
  96. In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5‐HT2AR
    Eline Pottie, Christophe Pol Stove · 2022 · Journal of Neurochemistry
  97. Engineering and exploiting synthetic allostery of NanoLuc luciferase
    Zhong Guo, Rinky D. Parakra, Ying Xiong, Wayne A. Johnston, Patricia M. Walden, Selvakumar Edwardraja, Shayli Varasteh Moradi, Jacobus P J Ungerer, Hui‐wang Ai, Jonathan J. Phillips et al. · 2022 · Nature Communications
  98. An extended conformation of SARS-CoV-2 main protease reveals allosteric targets
    Zengchao Sun, Lu Wang, Xiyang Li, Chengpeng Fan, Jianfeng Xu, Zhenzhong Shi, Huarui Qiao, Zhongyun Lan, Xin Zhang, Lingyun Li et al. · 2022 · Proceedings of the National Academy of Sciences
  99. Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
    Lihua Zhao, Qingning Yuan, Antao Dai, Xinheng He, Chuan-Wei Chen, Chao Zhang, Youwei Xu, Yan Zhou, Ming‐Wei Wang, Dehua Yang et al. · 2022 · Acta Pharmacologica Sinica
  100. PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs
    Teresa Cesaro, Yohei Hayashi, Fabian Borghese, Didier Vertommen, Fanny Wavreil, Thomas Michiels · 2021 · Scientific Reports