The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Diazo Compounds: Versatile Tools for Chemical Biology
Open accessAbstract
Diazo groups have broad and tunable reactivity. That and other attributes endow diazo compounds with the potential to be valuable reagents for chemical biologists. The presence of diazo groups in natural products underscores their metabolic stability and anticipates their utility in a biological context. The chemoselectivity of diazo groups, even in the presence of azido groups, presents many opportunities. Already, diazo compounds have served as chemical probes and elicited novel modifications of proteins and nucleic acids. Here, we review advances that have facilitated the chemical synthesis of diazo compounds, and we highlight applications of diazo compounds in the detection and modification of biomolecules.
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Tornøe, C. W., Christensen, C., & Meldal, M. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo011148j · Cited by 8,696
Effect of pegylation on pharmaceuticals
Harris, J. M., & Chess, R. B. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1033 · Cited by 3,431
Cited by
Thermal Stability and Explosive Hazard Assessment of Diazo Compounds and Diazo Transfer Reagents
Green, S. P., Wheelhouse, K. M., Payne, A. D., Hallett, J. P., Miller, P. W., & Bull, J. A. (2020) · Organic Process Research & Development · doi:10.1021/acs.oprd.9b00422 · Cited by 363
Metadata
- Authors
- Mix, K. A., Aronoff, M. R., & Raines, R. T.
- Venue
- ACS Chemical Biology
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-10-26
- Volume
- 11
- Issue
- 12
- Pages
- 3233-3244
- ISSN
- 1554-8929 (ISSN-L)
- 1554-8937
- OpenAlex
- W2530985860
- Cited by
- 242
- References
- 2
- FWCI
- 6.24
- Type
- journal article
- Language
- en
- Open access
- green
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