The DOI matches its Crossref record; 126 of the 127 references it cites were found in a registry or an index.
100th Anniversary of Macromolecular Science Viewpoint: Degradable Polymers from Radical Ring-Opening Polymerization: Latest Advances, New Directions, and Ongoing Challenges
Open accessAbstract
Radical ring-opening polymerization (rROP) allows facile incorporation of labile groups (e.g., ester) into the main chain of vinyl polymers to obtain (bio)degradable materials. rROP has focused a lot of attention especially since the advent of reversible deactivation radical polymerization (RDRP) techniques and is still incredibly moving forward, as attested by the numerous achievements in terms of monomer synthesis, macromolecular engineering, and potential biomedical applications of the resulting degradable polymers. In the present Viewpoint, we will cover the latest progress made in rROP in the last ∼5 years, such as its recent directions, its remaining limitations, and the ongoing challenges. More specifically, this will be achieved through the three different classes of monomers that recently caught most of the attention: cyclic ketene acetals (CKA), thionolactones, and macrocyclic monomers.
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“However, the rROP approach requires delicate design of the cyclic monomer to achieve high reactivity and to control the ratio of ring-opened and cyclic structures.”
From Direct Radical Copolymerizations of Thioamides To Generate Vinyl Polymers with Degradable Thioether Bonds in the Backbones (2023) · cites this paper as [22]
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Cites
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Hu, Y., Li, C., Hu, C., Shen, W., Yan, G., Hu, H., & Liang, C. (2026) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.6c01055
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Sugai, K., Aoshima, S., & Kanazawa, A. (2026) · Macromolecules · doi:10.1021/acs.macromol.6c01565
Functional cyclic disulfides enable multi-pathway degradable polyvinyls
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Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals
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Gao, P., Jiang, Y., Ha‐Duong, T., & Nicolas, J. (2026) · Angewandte Chemie · doi:10.1002/ange.6392855
Self-citationGao, P., Jiang, Y., Ha‐Duong, T., & Nicolas, J. (2026) · Angewandte Chemie International Edition · doi:10.1002/anie.6392855
Self-citationMagro, A., Levkovsky, I. O., Murata, H., Lorandi, F., Benetti, E. M., & Matyjaszewski, K. A. (2026) · Angewandte Chemie · doi:10.1002/ange.9026373
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Synthesis and Properties of Oxidatively Degradable Poly(Butyl Acrylate)Preprint
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Metadata
- Authors
- Pesenti, T., & Nicolas, J.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Nicolas, Julien
- Venue
- ACS Macro Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-12-02
- Volume
- 9
- Issue
- 12
- Pages
- 1812-1835
- ISSN
- 2161-1653 (ISSN-L)
- OpenAlex
- W3110095379
- Cited by
- 214
- References
- 127
- Citations by year
- 2026: 38 · 2025: 38 · 2024: 45 · 2023: 42 · 2022: 32 · 2021: 18
- Type
- journal article
- Language
- en
- Open access
- green
- hal.science
- Licence
- Locations
- ACS Macro Letters (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- Funders
- Agence Nationale de la Recherche (ANR-11-JS08-0005, ANR-15-CE08-0019)
- Centre National de la Recherche Scientifique
- Ministre de l'Enseignement sup?rieur, de la Recherche et de l'Innovation
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer composites and self-healing
- Keywords
- radical ring-opening polymerization, degradable polymers, bio-based polymers, controlled radical polymerization, cyclic ketene acetals, thionolactones, macrocyclic monomers, macromolecular engineering, biomedical applications, monomer synthesis
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