Design of polymeric nanoparticles for biomedical delivery applications

Strategies in the design of nanoparticles for therapeutic applications

Petros, R. A., & DeSimone, J. M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd2591 · Cited by 3,651 · see citing works

Transdermal drug delivery

Prausnitz, M. R., & Langer, R. (2008) · Nature Biotechnology · doi:10.1038/nbt.1504 · Cited by 3,519 · see citing works

The effect of particle design on cellular internalization pathways

Gratton, S. E. A., Ropp, P. A., Pohlhaus, P. D., Luft, J. C., Madden, V. J., Napier, M. E., & DeSimone, J. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801763105 · Cited by 2,918 · see citing works

Shape effects of filaments versus spherical particles in flow and drug delivery

Geng, Y., Dalhaimer, P., Cai, S., Tsai, R., Tewari, M., Minko, T., & Discher, D. E. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.70 · Cited by 2,565 · see citing works

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Davis, M. E., Zuckerman, J. E., Choi, C. H. J., Seligson, D. B., Tolcher, A. W., Alabi, C. A., Yen, Y., Heidel, J. D., & Ribas, A. (2010) · Nature · doi:10.1038/nature08956 · Cited by 2,508 · see citing works

Endocytosis of nanomedicines

Sahay, G., Alakhova, D. Y., & Kabanov, A. V. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.01.036 · Cited by 2,181 · see citing works

Role of target geometry in phagocytosis

Champion, J. A., & Mitragotri, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600997103 · Cited by 2,082 · see citing works

Designing dendrimers for biological applications

Lee, C., MacKay, J. A., Fréchet, J. M. J., & Szoka, F. C. (2005) · Nature Biotechnology · doi:10.1038/nbt1171 · Cited by 2,046 · see citing works

Ultralow‐Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications

Jiang, S., & Cao, Z. (2009) · Advanced Materials · doi:10.1002/adma.200901407 · Cited by 2,034 · see citing works

Dendrimers in biomedical applications—reflections on the field

Svenson, S., & Tomalia, D. A. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.09.018 · Cited by 1,925 · see citing works

Micellar Nanocarriers: Pharmaceutical Perspectives

Torchilin, V. P. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9132-0 · Cited by 1,910 · see citing works

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

Lai, S. K., Wang, Y.-Y., & Hanes, J. S. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.11.002 · Cited by 1,827 · see citing works

Immunological properties of engineered nanomaterials

Dobrovolskaia, M. A., & McNeil, S. E. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.223 · Cited by 1,823 · see citing works

Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials

Iha, R. K., Wooley, K. L., Nyström, A. M., Burke, D. J., Kade, M. J., & Hawker, C. J. (2009) · Chemical Reviews · doi:10.1021/cr900138t · Cited by 1,468 · see citing works

Exploring polyethylenimine‐mediated DNA transfection and the proton sponge hypothesis

Akinc, A., Thomas, M., Klibanov, A. M., & Langer, R. (2004) · The Journal of Gene Medicine · doi:10.1002/jgm.696 · Cited by 1,339 · see citing works

An Inverted Hexagonal Phase of Cationic Liposome-DNA Complexes Related to DNA Release and Delivery

Koltover, I., Salditt, T., Rädler, J. O., & Safinya, C. R. (1998) · Science · doi:10.1126/science.281.5373.78 · Cited by 1,336 · see citing works

The convergence of synthetic organic and polymer chemistries

Hawker, C. J., & Wooley, K. L. (2005) · Science · doi:10.1126/science.1109778 · Cited by 1,298 · see citing works

Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles

Verma, A., Uzun, O., Hu, Y., Hu, Y., Han, H., Watson, N., Chen, S., Irvine, D. J., & Stellacci, F. (2008) · Nature Materials · doi:10.1038/nmat2202 · Cited by 1,268 · see citing works

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

Iversen, T., Skotland, T., & Sandvig, K. (2011) · Nano Today · doi:10.1016/j.nantod.2011.02.003 · Cited by 1,235 · see citing works

Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery

Nishiyama, N., & Kataoka, K. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.05.006 · Cited by 1,052 · see citing works

Block Copolymer Assembly via Kinetic Control

Cui, H., Chen, Z., Zhong, S., Wooley, K. L., & Pochan, D. J. (2007) · Science · doi:10.1126/science.1141768 · Cited by 1,049 · see citing works

Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility

O’Reilly, R. K., Hawker, C. J., & Wooley, K. L. (2006) · Chemical Society Reviews · doi:10.1039/b514858h · Cited by 939 · see citing works

Minireview: Nanoparticles and the Immune System

Zolnik, B. S., González-Fernández, A., Sadrieh, N., & Dobrovolskaia, M. A. (2010) · Endocrinology · doi:10.1210/en.2009-1082 · Cited by 914 · see citing works

Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging

Bartlett, D. W., Su, H. C., Hildebrandt, I. J., Weber, W., & Davis, M. E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707461104 · Cited by 808 · see citing works

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

Wilson, D. S., Dalmasso, G., Wang, L., Sitaraman, S. V., Merlin, D., & Murthy, N. (2010) · Nature Materials · doi:10.1038/nmat2859 · Cited by 752 · see citing works

Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability

Hong, S., Leroueil, P. R., Janus, E. K., Peters, J. L., Kober, M.-M., Islam, M. T., Orr, B. G., Baker, J. R., & Holl, M. M. B. (2006) · Bioconjugate Chemistry · doi:10.1021/bc060077y · Cited by 686 · see citing works

Stimuli-responsive molecular brushes

Lee, H., Pietrasik, J., Sheiko, S. S., & Matyjaszewski, K. A. (2009) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2009.11.002 · Cited by 653 · see citing works

NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Hamaguchi, T., Matsumura, Y., Suzuki, M., Shimizu, K., Goda, R., Nakamura, I., Nakatomi, I., Yokoyama, M., Kataoka, K., & Kakizoe, T. (2005) · British Journal of Cancer · doi:10.1038/sj.bjc.6602479 · Cited by 565 · see citing works

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

Muro, S., Garnacho, C., Champion, J. A., Leferovich, J. M., Gajewski, C., Schuchman, E. H., Mitragotri, S., & Muzykantov, V. R. (2008) · Molecular Therapy · doi:10.1038/mt.2008.127 · Cited by 564 · see citing works

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Cheng, Y., Zhao, L., Li, Y., & Xu, T. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00097c · Cited by 516 · see citing works

Polyester Dendritic Systems for Drug Delivery Applications:  In Vitro and In Vivo Evaluation

Padilla De Jesús, O. L., Ihre, H. R., Gagne, L., Fréchet, J. M. J., & Szoka, F. C. (2002) · Bioconjugate Chemistry · doi:10.1021/bc010103m · Cited by 507 · see citing works

Preclinical and clinical studies of anticancer agent‐incorporating polymer micelles

Matsumura, Y., & Kataoka, K. (2009) · Cancer Science · doi:10.1111/j.1349-7006.2009.01103.x · Cited by 500 · see citing works

Nanoparticles that communicate in vivo to amplify tumour targeting

Park, J., Lin, K., Singh, N., Schwöppe, C., Mesters, R. M., Berdel, W. E., Ruoslahti, E. I., Sailor, M. J., von Maltzhan, G., & Bhatia, S. N. (2010) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 500 · see citing works

pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates

Felber, A. E., Dufresne, M.-H., & Leroux, J. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.09.006 · Cited by 480 · see citing works

Lactosylated Poly(ethylene glycol)-siRNA Conjugate through Acid-Labile β-Thiopropionate Linkage to Construct pH-Sensitive Polyion Complex Micelles Achieving Enhanced Gene Silencing in Hepatoma Cells

Oishi, M., Nagasaki, Y., Itaka, K., Nishiyama, N., & Kataoka, K. (2005) · Journal of the American Chemical Society · doi:10.1021/ja044941d · Cited by 477 · see citing works

Self-Assembled Targeted Nanoparticles: Evolution of Technologies and Bench to Bedside Translation

Shi, J., Xiao, Z., Kamaly, N., & Farokhzad, O. C. (2011) · Accounts of Chemical Research · doi:10.1021/ar200054n · Cited by 476 · see citing works

Chemically modified siRNA: tools and applications

Watts, J. K., Deleavey, G. F., & Damha, M. J. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2008.05.007 · Cited by 431 · see citing works

Cell Penetrating Peptides: Intracellular Pathways and Pharmaceutical Perspectives

Patel, L. N., Zaro, J. L., & Shen, W. (2007) · Pharmaceutical Research · doi:10.1007/s11095-007-9303-7 · Cited by 426 · see citing works

Development of a novel endosomolytic diblock copolymer for siRNA delivery

Convertine, A. J., Benoit, D. S. W., Duvall, C. L., Hoffman, A. S., & Stayton, P. S. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.10.004 · Cited by 407 · see citing works

Nanotheranostics and image-guided drug delivery: current concepts and future directions

Lammers, T., Kiessling, F., Hennink, W. E., & Storm, G. (2010) · Molecular Pharmaceutics · doi:10.1021/mp100228v · Cited by 397 · see citing works

Core-Clickable PEG-Branch-Azide Bivalent-Bottle-Brush Polymers by ROMP: Grafting-Through and Clicking-To

Johnson, J. A., Lu, Y. Y., Burts, A. O., Lim, Y., Finn, M. G., Koberstein, J. T., Turro, N. J., Tirrell, D. A., & Grubbs, R. H. (2010) · Journal of the American Chemical Society · doi:10.1021/ja108441d · Cited by 354 · see citing works

Drug-Loaded, Bivalent-Bottle-Brush Polymers by Graft-through ROMP

Johnson, J. A., Lu, Y. Y., Burts, A. O., Xia, Y., Durrell, A. C., Tirrell, D. A., & Grubbs, R. H. (2010) · Macromolecules · doi:10.1021/ma1021506 · Cited by 343 · see citing works

Stereocomplex Block Copolymer Micelles: Core−Shell Nanostructures with Enhanced Stability

Kang, N., Perron, M., Prud'homme, R. E., Zhang, Y., Gaucher, G., & Leroux, J. (2005) · Nano Letters · doi:10.1021/nl048037v · Cited by 334 · see citing works

Fast Release of Lipophilic Agents from Circulating PEG-PDLLA Micelles Revealed by<i>in Vivo</i>Förster Resonance Energy Transfer Imaging

Chen, H., Kim, S., He, W., Wang, H., Low, P. S., Park, K., & Cheng, J.-X. (2008) · Langmuir · doi:10.1021/la703570m · Cited by 311 · see citing works

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

Hyde, S. C., Pringle, I. A., Abdullah, S., Lawton, A. E., Davies, L. A., Varathalingam, A., Nunez-Alonso, G. A., Green, A.-M., Bazzani, R. P., Jones, S., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt1399 · Cited by 308 · see citing works

Hydrolysable core-crosslinked thermosensitive polymeric micelles: Synthesis, characterisation and in vivo studies

Rijcken, C. J. F., Snel, C. J., Schiffelers, R. M., van Nostrum, C. F., & Hennink, W. E. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.08.047 · Cited by 278 · see citing works

Isoforms of caveolin-1 and caveolar structure

Fujimoto, T., Kogo, H., Nomura, R., & Une, T. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.19.3509 · Cited by 251 · see citing works

Covalently cross-linked amphiphilic block copolymer micelles

van Nostrum, C. F. (2011) · Soft Matter · doi:10.1039/c0sm00999g · Cited by 242 · see citing works

Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake

Zhang, K., Fang, H., Chen, Z., Taylor, J., & Wooley, K. L. (2008) · Bioconjugate Chemistry · doi:10.1021/bc800160b · Cited by 202 · see citing works

Assessment of the Integrity of Poly(caprolactone)-b-poly(ethylene oxide) Micelles under Biological Conditions: A Fluorogenic-Based Approach

Savić, R., Azzam, T., Eisenberg, A., & Maysinger, D. (2006) · Langmuir · doi:10.1021/la0531998 · Cited by 191 · see citing works

Dynamic Cylindrical Assembly of Triblock Copolymers by a Hierarchical Process of Covalent and Supramolecular Interactions

Zhou, L., Ma, J., Lee, N. S., & Wooley, K. L. (2011) · Journal of the American Chemical Society · doi:10.1021/ja109191z · Cited by 179 · see citing works

Thiolated Chitosan/DNA Nanocomplexes Exhibit Enhanced and Sustained Gene Delivery

Lee, D., Zhang, W., Shirley, S. A., Kong, X., Hellermann, G., Lockey, R. F., & Mohapatra, S. S. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9136-9 · Cited by 178 · see citing works

Emerging links between surface nanotechnology and endocytosis: Impact on nonviral gene delivery

Adler, A. F., & Leong, K. W. (2010) · Nano Today · doi:10.1016/j.nantod.2010.10.007 · Cited by 169 · see citing works

A Family of Hierarchically Self‐Assembling Linear‐Dendritic Hybrid Polymers for Highly Efficient Targeted Gene Delivery

Wood, K. C., Little, S. R., Langer, R., & Hammond, P. T. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200502152 · Cited by 168 · see citing works

64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: synthesis, radiolabeling, and biologic evaluation.

Rossin, R., Pan, D., Qi, K., Turner, J. L., Sun, X., Wooley, K. L., & Welch, M. J. (2005) · PubMed · Cited by 161 · see citing works

Synthesis and Characterization of Core–Shell Star Copolymers for In Vivo PET Imaging Applications

Fukukawa, K., Rossin, R., Hagooly, A., Pressly, E. D., Hunt, J. N., Messmore, B. W., & Hawker, C. J. (2008) · Biomacromolecules · doi:10.1021/bm7014152 · Cited by 150 · see citing works

Chitosan‐NAC nanoparticles as a vehicle for nasal absorption enhancement of insulin

Wang, X., Zheng, C., Wu, Z., Teng, D., Zhang, X., Wang, Z., & Li, C. (2008) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31161 · Cited by 147 · see citing works

Advances in Drug Delivery

Timko, B. P., Whitehead, K. A., Gao, W., Kohane, D. S., Farokhzad, O. C., Anderson, D. G., & Langer, R. (2011) · Annual Review of Materials Research · doi:10.1146/annurev-matsci-062910-100359 · Cited by 143 · see citing works

Ligand‐Clustered “Patchy” Nanoparticles for Modulated Cellular Uptake and In Vivo Tumor Targeting

Poon, Z., Chen, S., Engler, A. C., Lee, H., Atas, E., von Maltzahn, G., Bhatia, S. N., & Hammond, P. T. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201003445 · Cited by 140 · see citing works

Structural Effects on the Biodistribution and Positron Emission Tomography (PET) Imaging of Well-Defined 64 Cu-Labeled Nanoparticles Comprised of Amphiphilic Block Graft Copolymers

Pressly, E. D., Rossin, R., Hagooly, A., Fukukawa, K., Messmore, B. W., Welch, M. J., Wooley, K. L., Lamm, M. S., Hule, R. A., Pochan, D. J., et al. (2007) · Biomacromolecules · doi:10.1021/bm700541e · Cited by 128 · see citing works

Polymeric Micelles with Ionic Cores Containing Biodegradable Cross-Links for Delivery of Chemotherapeutic Agents

Kim, J. O., Sahay, G., Kabanov, A. V., & Bronich, T. K. (2010) · Biomacromolecules · doi:10.1021/bm9013364 · Cited by 123 · see citing works

Polymeric Micellar Delivery Systems in Oncology

Matsumura, Y. (2008) · Japanese Journal of Clinical Oncology · doi:10.1093/jjco/hyn116 · Cited by 121 · see citing works

Nanoparticles with Tunable Internal Structure from Triblock Copolymers of PAA-b-PMA-b-PS

Hales, K., Chen, Z., Wooley, K. L., & Pochan, D. J. (2008) · Nano Letters · doi:10.1021/nl8013082 · Cited by 110 · see citing works

Design, Synthesis, and Biological Evaluation of a Robust, Biodegradable Dendrimer

van der Poll, D. G., Ferguson, H. M., Floyd, W. C., Guillaudeu, S. J., Jerger, K., Szoka, F. C., & Fréchet, J. M. J. (2010) · Bioconjugate Chemistry · doi:10.1021/bc900553n · Cited by 102 · see citing works

pH-Sensitive brush polymer-drug conjugates by ring-opening metathesis copolymerization

Zou, J., Jafr, G., Themistou, E., Yap, Y. S., Wintrob, Z. A. P., Alexandridis, P., Ceacareanu, A. C., & Cheng, C. (2011) · Chemical Communications · doi:10.1039/c0cc05531j · Cited by 102 · see citing works

Supramolecular nanostructures designed for high cargo loading capacity and kinetic stability

Yang, C. H., Tan, J. P. K., Cheng, W., Attia, A. B. E., Ting, C. T. Y., Nelson, A., Hedrick, J. L., & Yang, Y. Y. (2010) · Nano Today · doi:10.1016/j.nantod.2010.10.006 · Cited by 98 · see citing works

Injectable PAMAM Dendrimer–PEG Hydrogels for the Treatment of Genital Infections: Formulation and in Vitro and in Vivo Evaluation

Navath, R. S., Menjoge, A. R., Dai, H., Romero, R. J., Kannan, S., & Kannan, R. M. (2011) · Molecular Pharmaceutics · doi:10.1021/mp200027z · Cited by 95 · see citing works

Evaluation of Multivalent, Functional Polymeric Nanoparticles for Imaging Applications

Shokeen, M., Pressly, E. D., Hagooly, A., Zheleznyak, A., Ramos, N. N., Fiamengo, A. L., Welch, M. J., Hawker, C. J., & Anderson, C. J. (2011) · ACS Nano · doi:10.1021/nn102278w · Cited by 92 · see citing works

Facile, Efficient Approach to Accomplish Tunable Chemistries and Variable Biodistributions for Shell Cross-Linked Nanoparticles

Sun, G., Hagooly, A., Xu, J., Nyström, A. M., Li, Z., Rossin, R., Moore, D. A., Wooley, K. L., & Welch, M. J. (2008) · Biomacromolecules · doi:10.1021/bm800246x · Cited by 89 · see citing works

Development and optimization of a process for automated recovery of single cells identified by microengraving

Choi, J.-H., Ogunniyi, A. O., Du, M., Du, M., Kretschmann, M., Eberhardt, J., & Love, J. C. (2010) · Biotechnology Progress · doi:10.1002/btpr.374 · Cited by 81 · see citing works

Multicompartment Polymer Nanostructures with Ratiometric Dual-Emission pH-Sensitivity

Sun, G., Cui, H., Lin, L. Y., Lee, N. S., Yang, C., Neumann, W. L., Freskos, J. N., Shieh, J. J., Dorshow, R. B., & Wooley, K. L. (2011) · Journal of the American Chemical Society · doi:10.1021/ja200182t · Cited by 80 · see citing works

Folate‐mediated cell uptake of shell‐crosslinked spheres and cylinders

Zhang, K., Rossin, R., Hagooly, A., Chen, Z., Welch, M. J., & Wooley, K. L. (2008) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.23020 · Cited by 80 · see citing works

Intracellular organelle-targeted non-viral gene delivery systems

Won, Y.-W., Lim, K. S., & Kim, Y. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.01.013 · Cited by 75 · see citing works

Multifunctional siRNA delivery system: Polyelectrolyte complex micelles of six‐arm PEG conjugate of siRNA and cell penetrating peptide with crosslinked fusogenic peptide

Choi, S. W., Hyeon, L. S., Mok, H., & Park, T. G. (2009) · Biotechnology Progress · doi:10.1002/btpr.310 · Cited by 74 · see citing works

Cationic shell-crosslinked knedel-like nanoparticles for highly efficient gene and oligonucleotide transfection of mammalian cells

Zhang, K., Fang, H., Wang, Z., Taylor, J., & Wooley, K. L. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.10.057 · Cited by 63 · see citing works

Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin

Lin, L. Y., Lee, N. S., Zhu, J., Nyström, A. M., Pochan, D. J., Dorshow, R. B., & Wooley, K. L. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.01.009 · Cited by 60 · see citing works

Cationic Shell-Cross-Linked Knedel-like (cSCK) Nanoparticles for Highly Efficient PNA Delivery

Fang, H., Zhang, K., Shen, G., Wooley, K. L., & Taylor, J. (2009) · Molecular Pharmaceutics · doi:10.1021/mp800199w · Cited by 58 · see citing works

Structure-activity relationships of cationic shell-crosslinked knedel-like nanoparticles: Shell composition and transfection efficiency/cytotoxicity

Zhang, K., Fang, H., Wang, Z., Li, Z., Taylor, J., & Wooley, K. L. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.10.033 · Cited by 58 · see citing works

siRNA nanocarriers based on methacrylic acid copolymers

Felber, A. E., Castagner, B., Elsabahy, M., Deleavey, G. F., Damha, M. J., & Leroux, J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.12.012 · Cited by 58 · see citing works

Shell crosslinked nanoparticles carrying silver antimicrobials as therapeutics

Li, Y., Hindi, K. M., Watts, K. M., Taylor, J. B., Zhang, K., Li, Z., Hunstad, D. A., Cannon, C. L., Youngs, W. J., & Wooley, K. L. (2009) · Chemical Communications · doi:10.1039/b916559b · Cited by 52 · see citing works

In VivoEvaluation of pH-Sensitive Polymer-Based Immunoliposomes Targeting the CD33 Antigen

Simard, P., & Leroux, J. (2010) · Molecular Pharmaceutics · doi:10.1021/mp900261m · Cited by 47 · see citing works

Bioresponsive hyperbranched polymers for siRNA and miRNA delivery

Rahbek, U. L., Nielsen, A. F., Dong, M., You, Y., Chauchereau, A., Oupický, D., Besenbacher, F., Kjems, J., & Howard, K. A. (2010) · Journal of drug targeting · doi:10.3109/1061186x.2010.527982 · Cited by 44 · see citing works

From Phage Display to Dendrimer Display: Insights into Multivalent Binding

Bastings, M. M. C., Helms, B. A., van Baal, I., Hackeng, T. M., Merkx, M., & Meijer, E. W. (2011) · Journal of the American Chemical Society · doi:10.1021/ja110700x · Cited by 41 · see citing works

Synthesis and enzymatic stability of PEGylated oligonucleotide duplexes and their self-assemblies with polyamidoamine dendrimers

Elsabahy, M., Zhang, M., Gan, S.-M., Waldron, K. C., & Leroux, J. (2007) · Soft Matter · doi:10.1039/b714221h · Cited by 34 · see citing works

Well-defined Cationic Shell Crosslinked Nanoparticles for Efficient Delivery of DNA or Peptide Nucleic Acids

Zhang, K., Fang, H., Shen, G., Taylor, J., & Wooley, K. L. (2009) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200902-010aw · Cited by 34 · see citing works

Influence of Nanostructure Morphology on Host Capacity and Kinetics of Guest Release

Lee, N. S., Lin, L. Y., Neumann, W. L., Freskos, J. N., Karwa, A. S., Shieh, J. J., Dorshow, R. B., & Wooley, K. L. (2011) · Small · doi:10.1002/smll.201100567 · Cited by 28 · see citing works

Nanoparticles that communicate in vivo to amplify tumour targeting

von Maltzahn, G., Park, J., Lin, K. Y.-M., et al. (2011) · Nature Materials · doi:10.1038/nmat3049 · Cited by 18 · see citing works

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

Bobo, D., Robinson, K. J., Islam, J., Thurecht, K. J., & Corrie, S. R. (2016) · Pharmaceutical Research · doi:10.1007/s11095-016-1958-5 · Cited by 2,586 · see citing works

Engineered Nanoparticles for Drug Delivery in Cancer Therapy

Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164 · see citing works

Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies

Ulbrich, K., Holá, K., Šubr, V., Bakandritsos, A., Tuček, J., & Zbořil, R. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00589 · Cited by 1,741 · see citing works

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

Karimi, M., Ghasemi, A., Zangabad, P. S., Rahighi, R., Basri, S. M. M., Mirshekari, H., Amiri, M., Shafaei, Z., Aslani, A., Bozorgomid, M., et al. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00798d · Cited by 1,526 · see citing works

Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles

Foroozandeh, P., & Aziz, A. A. (2018) · Nanoscale Research Letters · doi:10.1186/s11671-018-2728-6 · Cited by 1,393 · see citing works

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

Zhang, Y.-N., Poon, W., Tavares, A. J., McGilvray, I. D., & Chan, W. C. W. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.01.020 · Cited by 1,358 · see citing works

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

Nicolas, J., Mura, S., Brambilla, D., Mackiewicz, N., & Couvreur, P. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35265f · Cited by 1,270 · see citing works

Light-Controlled Radical Polymerization: Mechanisms, Methods, and Applications

Chen, M., Zhong, M., & Johnson, J. A. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00671 · Cited by 1,201 · see citing works

Nanomaterials for cancer therapy: current progress and perspectives

Cheng, Z., Li, M., Dey, R., & Chen, Y. (2021) · Journal of Hematology & Oncology · doi:10.1186/s13045-021-01096-0 · Cited by 1,193 · see citing works

Nanoparticles for Cancer Therapy: Current Progress and Challenges

Gavas, S., Quazi, S., & Karpiński, T. M. (2021) · Nanoscale Research Letters · doi:10.1186/s11671-021-03628-6 · Cited by 1,069 · see citing works

Nanoparticle‐Mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

Duan, X., Chan, C., & Lin, W. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201804882 · Cited by 1,035 · see citing works

Reversible-deactivation radical polymerization (Controlled/living radical polymerization): From discovery to materials design and applications

Corrigan, N. A., Jung, K., Moad, G., Hawker, C. J., Matyjaszewski, K. A., & Boyer, C. A. (2020) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2020.101311 · Cited by 984 · see citing works

Molecular-based design and emerging applications of nanoporous carbon spheres

Liu, J., Wickramaratne, N. P., Qiao, S. Z., & Jaroniec, M. (2015) · Nature Materials · doi:10.1038/nmat4317 · Cited by 954 · see citing works

Smart Nanoparticles for Drug Delivery Application: Development of Versatile Nanocarrier Platforms in Biotechnology and Nanomedicine

Lombardo, D., Kiselev, M. A., & Caccamo, M. T. (2019) · Journal of Nanomaterials · doi:10.1155/2019/3702518 · Cited by 864 · see citing works

Star Polymers

Ren, J. M., McKenzie, T. G., Fu, Q., Wong, E. H. H., Xu, J., An, Z., Shanmugam, S., Davis, T. P., Boyer, C. A., & Qiao, G. G. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00008 · Cited by 842 · see citing works

Methods and strategies for the synthesis of diverse nanoparticles and their applications: a comprehensive overview

Dhand, C., Dwivedi, N., Loh, X. J., Ying, A. N. J., Verma, N. K., Beuerman, R. W., Lakshminarayanan, R., & Ramakrishna, S. (2015) · RSC Advances · doi:10.1039/c5ra19388e · Cited by 799 · see citing works

Insight into nanoparticle cellular uptake and intracellular targeting

Yameen, B., Choi, W. I., Vilos, C., Swami, A., Shi, J., & Farokhzad, O. C. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.06.038 · Cited by 789 · see citing works

Nanotechnology-based antimicrobials and delivery systems for biofilm-infection control

Liu, Y., Shi, L., Su, L., van der Mei, H. C., Jutte, P. C., Ren, Y., & Busscher, H. J. (2019) · Chemical Society Reviews · doi:10.1039/c7cs00807d · Cited by 737 · see citing works

In Vivo Bio‐Safety Evaluations and Diagnostic/Therapeutic Applications of Chemically Designed Mesoporous Silica Nanoparticles

Chen, Y., Chen, H., & Shi, J. (2013) · Advanced Materials · doi:10.1002/adma.201205292 · Cited by 726 · see citing works

Polymeric nanoparticles: A study on the preparation variables and characterization methods

Crucho, C. I. C., & Barros, M. T. (2017) · Materials Science and Engineering C · doi:10.1016/j.msec.2017.06.004 · Cited by 700 · see citing works

Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation

Soni, K. S., Desale, S. S., & Bronich, T. K. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.11.009 · Cited by 700 · see citing works

Form Follows Function: Nanoparticle Shape and Its Implications for Nanomedicine

Kinnear, C., Moore, T. L., Rodríguez‐Lorenzo, L., Rothen‐Rutishauser, B., & Petri‐Fink, A. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00194 · Cited by 673 · see citing works

Magnetic nanocarriers: Evolution of spinel ferrites for medical applications

Amiri, M., Salavati‐Niasari, M., & Akbari, A. (2019) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2019.01.003 · Cited by 654 · see citing works

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645 · see citing works

Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications

Croissant, J. G., Fatieiev, Y., Almalik, A., & Khashab, N. M. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700831 · Cited by 601 · see citing works

Magnetic nanoparticle-based therapeutic agents for thermo-chemotherapy treatment of cancer

Hervault, A., & Thanh, N. T. K. (2014) · Nanoscale · doi:10.1039/c4nr03482a · Cited by 584 · see citing works

Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy

Zhong, Y., Meng, F., Deng, C., & Zhong, Z. (2014) · Biomacromolecules · doi:10.1021/bm5003009 · Cited by 548 · see citing works

Metal Oxide Nanoparticles as Biomedical Materials

Nikolova, M. P., & Chavali, M. S. (2020) · Biomimetics · doi:10.3390/biomimetics5020027 · Cited by 510 · see citing works

Polymeric Nanostructures for Imaging and Therapy

Elsabahy, M., Heo, G. S., Lim, S., Sun, G., & Wooley, K. L. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00135 · Cited by 507 · see citing works

Targeted therapy using nanotechnology: focus on cancer

Sechi, M., Sanna, V., & Pala, N. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s36654 · Cited by 497 · see citing works

Structure–Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging

Zhou, Z., Yang, L., Gao, J., & Chen, X. S. (2019) · Advanced Materials · doi:10.1002/adma.201804567 · Cited by 488 · see citing works

Polymeric nanoparticles: the future of nanomedicine

Banik, B. L., Fattahi, P., & Brown, J. L. (2015) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1364 · Cited by 487 · see citing works

Activated Ester Containing Polymers: Opportunities and Challenges for the Design of Functional Macromolecules

Das, A., & Théato, P. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00291 · Cited by 482 · see citing works

Analyte-Responsive Hydrogels: Intelligent Materials for Biosensing and Drug Delivery

Culver, H. R., Clegg, J. R., & Peppas, N. A. (2017) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00533 · Cited by 483 · see citing works

Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy

Li, J., Rao, J., & Pu, K. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.025 · Cited by 469 · see citing works

Applications and Limitations of Dendrimers in Biomedicine

Chiş, A. A., Dobrea, C. M., Morgovan, C., Arseniu, A. M., Rus, L. L., Butucă, A., Juncan, A. M., Totan, M., Vonica-Țincu, A. L., Cormoș, G., et al. (2020) · Molecules · doi:10.3390/molecules25173982 · Cited by 469 · see citing works

Rare-earth metal–organic frameworks: from structure to applications

Saraci, F., Quezada‐Novoa, V., Donnarumma, P. R., & Howarth, A. J. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00292e · Cited by 466 · see citing works

Interlayer Hydrogen-Bonded Covalent Organic Frameworks as High-Performance Supercapacitors

Halder, A., Ghosh, M., Mohammed, A. K., Bera, S., Addicoat, M. A., Sasmal, H. S., Karak, S., Kurungot, S., & Banerjee, R. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.8b06460 · Cited by 455 · see citing works

Impact of nanoparticles on human and environment: review of toxicity factors, exposures, control strategies, and future prospects

Sajid, M., Ilyas, M. F., Basheer, C., Tariq, M., Daud, M., Baig, N., & Shehzad, F. (2014) · Environmental Science and Pollution Research · doi:10.1007/s11356-014-3994-1 · Cited by 453 · see citing works

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Zhao, Z., Ukidve, A., Krishnan, V., & Mitragotri, S. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.01.002 · Cited by 449 · see citing works

Cytokines as biomarkers of nanoparticle immunotoxicity

Elsabahy, M., & Wooley, K. L. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60064e · Cited by 408 · see citing works

Composites of Polymer Hydrogels and Nanoparticulate Systems for Biomedical and Pharmaceutical Applications

Zhao, F., Yao, D. S., Guo, R., Deng, L., Dong, A., & Zhang, J. (2015) · Nanomaterials · doi:10.3390/nano5042054 · Cited by 400 · see citing works

50th Anniversary Perspective: Functional Nanoparticles from the Solution Self-Assembly of Block Copolymers

Tritschler, U., Pearce, S., Gwyther, J., Whittell, G. R., & Ian Manners, A. (2017) · Macromolecules · doi:10.1021/acs.macromol.6b02767 · Cited by 375 · see citing works

Tailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstances

Holá, K., Marková, Z., Zoppellaro, G., Tuček, J., & Zbořil, R. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.02.003 · Cited by 372 · see citing works

Polymeric nanostructured materials for biomedical applications

Tang, Z., He, C., Tian, H., Ding, J., Hsiao, B. S., Chu, B., & Chen, X. (2016) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2016.05.005 · Cited by 364 · see citing works

Upconversion nanoparticles and their composite nanostructures for biomedical imaging and cancer therapy

Cheng, L., Wang, C., & Liu, Z. (2012) · Nanoscale · doi:10.1039/c2nr32311g · Cited by 359 · see citing works

Advanced bioactive nanomaterials for biomedical applications

Zhao, Y., Zhang, Z., Pan, Z., & Liu, Y. (2021) · Exploration · doi:10.1002/exp.20210089 · Cited by 359 · see citing works

Ligand-installed nanocarriers toward precision therapy

Mi, P., Cabral, H., & Kataoka, K. (2020) · Advanced Materials · doi:10.1002/adma.201902604 · Cited by 350 · see citing works

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

Rohovie, M. J., Nagasawa, M., & Swartz, J. R. (2016) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10049 · Cited by 341 · see citing works

Functional nanoparticles through π-conjugated polymer self-assembly

MacFarlane, L. R., Shaikh, H., Garcia-Hernandez, J. D., Vespa, M., Fukui, T., & Ian Manners, A. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-00233-4 · Cited by 342 · see citing works

Polymerization-induced thermal self-assembly (PITSA)

Figg, C. A., Simula, A., Gebre, K. A., Tucker, B. S., Haddleton, D. M., & Sumerlin, B. S. (2014) · Chemical Science · doi:10.1039/c4sc03334e · Cited by 332 · see citing works

Super-hydrophilic zwitterionic poly(carboxybetaine) and amphiphilic non-ionic poly(ethylene glycol) for stealth nanoparticles

Cao, Z., & Jiang, S. (2012) · Nano Today · doi:10.1016/j.nantod.2012.08.001 · Cited by 331 · see citing works

Polymerization-Induced Self-Assembly (PISA) – control over the morphology of nanoparticles for drug delivery applications

Karagöz, B., Esser, L., Duong, H. T. T., Basuki, J. S., Boyer, C. A., & Davis, T. P. (2013) · Polymer Chemistry · doi:10.1039/c3py01306e · Cited by 328 · see citing works

<scp>pH</scp> ‐Sensitive stimulus‐responsive nanocarriers for targeted delivery of therapeutic agents

Karimi, M., Eslami, M., Sahandi‐Zangabad, P., Mirab, F., Farajisafiloo, N., Shafaei, Z., Ghosh, D., Bozorgomid, M., Dashkhaneh, F., & Hamblin, M. R. (2016) · WIREs Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1389 · Cited by 327 · see citing works

Hyaluronic Acid–Based Activatable Nanomaterials for Stimuli‐Responsive Imaging and Therapeutics: Beyond CD44‐Mediated Drug Delivery

Choi, K. Y., Han, H. S., Lee, E. S., Shin, J. M., Almquist, B. D., Lee, D. S., & Park, J. H. (2019) · Advanced Materials · doi:10.1002/adma.201803549 · Cited by 320 · see citing works

Progress, challenges, and future of nanomedicine

Zhang, C., Yan, L., Wang, X., Zhu, S., Chen, C., Gu, Z., & Zhao, Y. (2020) · Nano Today · doi:10.1016/j.nantod.2020.101008 · Cited by 319 · see citing works

Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity

Zhang, P., Sun, F., Tsao, C., Liu, S., Jain, P. R., Sinclair, A., Hung, H., Bai, T., Wu, K., & Jiang, S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1512465112 · Cited by 316 · see citing works

Precipitation polymerization for fabrication of complex core–shell hybrid particles and hollow structures

Li, G. L., Möhwald, H., & Shchukin, D. G. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35517a · Cited by 314 · see citing works

A Dual-Emission Fluorescent Nanocomplex of Gold-Cluster-Decorated Silica Particles for Live Cell Imaging of Highly Reactive Oxygen Species

Chen, T., Hu, Y., Cen, Y., Chu, X., & Lu, Y. (2013) · Journal of the American Chemical Society · doi:10.1021/ja4035939 · Cited by 309 · see citing works

Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo

Zhong, Y., Goltsche, K., Cheng, L., Xie, F., Meng, F., Deng, C., Zhong, Z., & Haag, R. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.01.049 · Cited by 290 · see citing works

A Water‐Soluble, NIR‐Absorbing Quaterrylenediimide Chromophore for Photoacoustic Imaging and Efficient Photothermal Cancer Therapy

Liu, C., Zhang, S., Li, J., Wei, J., Müllen, K., & Yin, M. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201810541 · Cited by 288 · see citing works

Recent trends in the design of anticancer polymer prodrug nanocarriers

Delplace, V., Couvreur, P., & Nicolas, J. (2013) · Polymer Chemistry · doi:10.1039/c3py01384g · Cited by 287 · see citing works

Liquid–liquid phase separation during amphiphilic self-assembly

Ianiro, A., Wu, H., van Rijt, M. M. J., Vena, M. P., Keizer, A. D. A., Esteves, A. C. C., Tuinier, R., Friedrich, H., Sommerdijk, N. A. J. M., & Patterson, J. P. (2019) · Nature Chemistry · doi:10.1038/s41557-019-0210-4 · Cited by 283 · see citing works

Hydrogen-bonding organocatalysts for ring-opening polymerization

Thomas, C., & Bibal, B. (2013) · Green Chemistry · doi:10.1039/c3gc41806e · Cited by 278 · see citing works

Role of functionalization: strategies to explore potential nano-bio applications of magnetic nanoparticles

Bohara, R. A., Thorat, N. D., & Pawar, S. H. (2016) · RSC Advances · doi:10.1039/c6ra02129h · Cited by 279 · see citing works

Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

Zhang, M., Gao, S., Yang, D., Fang, Y., Lin, X., Jin, X., Liu, Y., Liu, X., Su, K., & Shi, K. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.033 · Cited by 277 · see citing works

Recent applications of immunomodulatory biomaterials for disease immunotherapy

Dai, H., Fan, Q., & Wang, C. (2022) · Exploration · doi:10.1002/exp.20210157 · Cited by 270 · see citing works

Application of Nanotechnology in Drug Delivery

Sezer, A. D. (2014) · InTech eBooks · doi:10.5772/57028 · Cited by 268 · see citing works

Application of the Nano-Drug Delivery System in Treatment of Cardiovascular Diseases

Deng, Y., Zhang, X., Shen, H., He, Q., Wu, Z., Liao, W., & Yuan, M. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00489 · Cited by 263 · see citing works

Flavonoids nanoparticles in cancer: Treatment, prevention and clinical prospects

Khan, H. Z., Ullah, H., Martorell, M., Valdés, S. C. E., Belwal, T., Tejada, S., Sureda, A., & Kamal, M. A. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.07.023 · Cited by 261 · see citing works

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy

Zhao, X. L., Yang, K., Zhao, R., Ji, T., Wang, X., Yang, X., Zhang, Y., Cheng, K., Liu, S., Hao, J., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.06.032 · Cited by 255 · see citing works

Mesoporous Silica Nanoparticles for Protein Protection and Delivery

Xu, C., Lei, C., & Yu, C. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00290 · Cited by 247 · see citing works

Nano-formulations of drugs: Recent developments, impact and challenges

Jeevanandam, J., Chan, Y. S., & Danquah, M. K. (2016) · Biochimie · doi:10.1016/j.biochi.2016.07.008 · Cited by 248 · see citing works

PAMAM dendrimer - cell membrane interactions

Fox, L. J., Richardson, R. M., & Briscoe, W. H. (2018) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2018.06.005 · Cited by 243 · see citing works

Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugs

Kumari, L., Choudhari, Y., Patel, P., Gupta, G. D., Singh, D., Rosenholm, J. M., Bansal, K. K., & Kurmi, B. D. (2023) · Life · doi:10.3390/life13051099 · Cited by 265 · see citing works

Reversing RAFT Polymerization: Near-Quantitative Monomer Generation Via a Catalyst-Free Depolymerization Approach

Wang, H. S., Truong, N. P., Pei, Z., Coote, M. L., & Anastasaki, A. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c00963 · Cited by 242 · see citing works

Metal Oxide Nanoparticles: Review of Synthesis, Characterization and Biological Effects

Negrescu, A. M., Killian, M. S., Raghu, S. N. V., Schmuki, P., Mazare, A., & Cîmpean, A. (2022) · Journal of Functional Biomaterials · doi:10.3390/jfb13040274 · Cited by 253 · see citing works

Chitosans for delivery of nucleic acids

Buschmann, M., Merzouki, A., Lavertu, M., Thibault, M., Jean, M., & Darras, V. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.07.005 · Cited by 229 · see citing works

Boron agents for neutron capture therapy

Hu, K., Yang, Z., Zhang, L., Xie, L., Wang, L., Xu, H., Josephson, L., Liang, S. H., & Zhang, M. (2019) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2019.213139 · Cited by 237 · see citing works

Co-delivery of chemotherapeutics and proteins for synergistic therapy

He, C., Tang, Z., Tian, H., & Chen, X. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.10.021 · Cited by 231 · see citing works

Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol)

Wang, Y., Quinsaat, J. E. Q., Ono, T., Maeki, M., Tokeshi, M., Isono, T., Tajima, K., Satoh, T., Sato, S., Miura, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19947-8 · Cited by 233 · see citing works

Hyperthermia using nanoparticles – Promises and pitfalls

Kaur, P., Aliru, M. L., Chadha, A. S., Asea, A. A. A., & Krishnan, S. (2016) · International Journal of Hyperthermia · doi:10.3109/02656736.2015.1120889 · Cited by 226 · see citing works

Non-genetic engineering of cells for drug delivery and cell-based therapy

Wang, Q., Cheng, H., Peng, H., Zhou, H., Li, P. Y., & Langer, R. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.12.003 · Cited by 225 · see citing works

Atomically precise organomimetic cluster nanomolecules assembled via perfluoroaryl-thiol SNAr chemistry

Qian, E. A., Wixtrom, A. I., Axtell, J. C., Saebi, A., Jung, D., Rehak, P. L., Han, Y., Moully, E. H., Mosallaei, D., Chow, S., et al. (2016) · Nature Chemistry · doi:10.1038/nchem.2686 · Cited by 224 · see citing works

Coordination-responsive drug release inside gold nanorod@metal-organic framework core–shell nanostructures for near-infrared-induced synergistic chemo-photothermal therapy

Li, Y., Jin, J., Wang, D., Lv, J., Hou, K., Liu, Y., Chen, C., & Tang, Z. (2017) · Nano Research · doi:10.1007/s12274-017-1874-y · Cited by 224 · see citing works

Multifunctional nanoparticles for targeted delivery of immune activating and cancer therapeutic agents

Feng, J., Liu, X., Li, L., Mallapragada, S. K., Narasimhan, B., & Wang, Q. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.10.012 · Cited by 222 · see citing works

Oral Squamous Cell Carcinoma: Current Treatment Strategies and Nanotechnology-Based Approaches for Prevention and Therapy

Gharat, S., Momin, M. M., & Bhavsar, C. (2016) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.2016016272 · Cited by 220 · see citing works

1D vs. 2D shape selectivity in the crystallization-driven self-assembly of polylactide block copolymers

Inam, M., Cambridge, G., Pitto‐Barry, A., Laker, Z. P. L., Wilson, N. R., Mathers, R. T., Dove, A. P., & O’Reilly, R. K. (2017) · Chemical Science · doi:10.1039/c7sc00641a · Cited by 220 · see citing works

Mesoporous Silica Nanoparticle-Supported Lipid Bilayers (Protocells) for Active Targeting and Delivery to Individual Leukemia Cells

Durfee, P. N., Lin, Y., Dunphy, D. R., Muñiz, A. J., Butler, K. S., Humphrey, K. R., Lokke, A. J., Agola, J. O., Chou, S. S., Chen, I., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b02819 · Cited by 219 · see citing works

100th Anniversary of Macromolecular Science Viewpoint: Degradable Polymers from Radical Ring-Opening Polymerization: Latest Advances, New Directions, and Ongoing Challenges

Pesenti, T., & Nicolas, J. (2020) · ACS Macro Letters · doi:10.1021/acsmacrolett.0c00676 · Cited by 214 · see citing works

Catalytically Active Single-Chain Polymeric Nanoparticles: Exploring Their Functions in Complex Biological Media

Liu, Y., Pujals, S., Stals, P. J. M., Pauloehrl, T., Presolski, S. I., Meijer, E. W., Albertazzi, L., & Palmans, A. R. A. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.8b00122 · Cited by 214 · see citing works

Scalable and uniform 1D nanoparticles by synchronous polymerization, crystallization and self-assembly

Boott, C. E., Gwyther, J., Harniman, R. L., Hayward, D. W., & Ian Manners, A. (2017) · Nature Chemistry · doi:10.1038/nchem.2721 · Cited by 212 · see citing works

Engineered nanomaterial uptake and tissue distribution: from cell to organism

Huwyler, J., Kettiger, H., Schipanski, A., & Wick, P. (2013) · International Journal of Nanomedicine · doi:10.2147/ijn.s49770 · Cited by 212 · see citing works

Nanomaterials for Wound Healing: Scope and Advancement

Kalashnikova, I. V., Das, S., & Seal, S. (2015) · Nanomedicine · doi:10.2217/nnm.15.82 · Cited by 209 · see citing works

Synthesis of silver nanoparticles using bacterial exopolysaccharide and its application for degradation of azo-dyes

Saravanan, C., Rajesh, R., Kaviarasan, T., Muthukumar, K., Kavitake, D., & Shetty, P. H. (2017) · Biotechnology Reports · doi:10.1016/j.btre.2017.02.006 · Cited by 207 · see citing works

Advanced Bottom‐Up Engineering of Living Architectures

Gaspar, V. M., Lavrador, P., Borges, J., Oliveira, M. B., & Mano, J. F. (2019) · Advanced Materials · doi:10.1002/adma.201903975 · Cited by 204 · see citing works

Nonviolent Self-Catabolic DNAzyme Nanosponges for Smart Anticancer Drug Delivery

Wang, J., Wang, H., Wang, H., He, S., Li, R., Deng, Z., Liu, X., & Wang, F. (2019) · ACS Nano · doi:10.1021/acsnano.9b01589 · Cited by 202 · see citing works

Recent advances in nanotheranostics for triple negative breast cancer treatment

Thakur, V., & Kutty, R. V. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1443-1 · Cited by 201 · see citing works

Gold Complexes in Anticancer Therapy: From New Design Principles to Particle‐Based Delivery Systems

Moreno‐Alcántar, G., Picchetti, P., & Casini, A. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202218000 · Cited by 204 · see citing works

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