The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Lignin Nanoparticle as a Novel Green Carrier for the Efficient Delivery of Resveratrol
Abstract
In this work, we have developed a novel green nanoparticle platform based on lignin without chemical modification. The alkali lignin (AL) was used to prepare nanoparticles with perfect spheres and well dispersibility via a simple self-assembly method by adding water to a methanol solution of AL. Finally, we showed that self-assembly of AL with the bioactive molecule resveratrol (RSV) and Fe 3 O 4 magnetic nanoparticles led to the formation of stable nanodrug carrier. In cytological and animal tests, the magnetic RSV-loaded lignin nanoparticles (AL/RSV/Fe 3 O 4 NPs) demonstrated good anticancer effects and enhanced in vitro RSV release and stability, drug accumulation, and better tumor reduction, as well lower adverse effects than free drugs, strongly supporting the AL NPs application as a new and highly efficient nanodelivery. Moreover, this renewable green material with its simple preparation technique and easy large-scale production would be a highly potential candidate for many poorly soluble drugs.
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Cites
Chemical modification of lignins: Towards biobased polymers
Laurichesse, S., & Avérous, L. (2014) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2013.11.004 · Cited by 2,058
Maeda, H. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.01.002 · Cited by 1,179
A holistic approach to targeting disease with polymeric nanoparticles
Cheng, C. J., Tietjen, G. T., Saucier-Sawyer, J. K., & Saltzman, W. M. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4503 · Cited by 480
Sahana, D. K., Mittal, G., Bhardwaj, V., & Kumar, M. N. V. R. (2008) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21158 · Cited by 260
Cited by
Lignin for Nano‐ and Microscaled Carrier Systems: Applications, Trends, and Challenges
Sipponen, M. H., Lange, H., Crestini, C., Henn, A., & Österberg, M. (2019) · ChemSusChem · doi:10.1002/cssc.201900480 · Cited by 284
Wang, H., Xiong, F., Tan, Y., Yang, J., Qing, Y., Chu, F., & Wu, Y. (2021) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.0c08780 · Cited by 77
pH-Responsive Lignin-Based Nanomicelles for Oral Drug Delivery
Cheng, L., Deng, B., Luo, W., Nie, S., Liu, X., Yin, Y., Liu, S., Wu, Z., Zhan, P., Zhang, L., et al. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b08171 · Cited by 77
Li, Y.-J., Li, H.-Y., Cao, X.-F., Sun, S.-N., & Sun, R.-C. (2018) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.8b02475 · Cited by 31
Song, X., Guo, W., Zhu, Z., Han, G., & Cheng, W. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128827 · Cited by 18
Metadata
- Authors
- Dai, L., Liu, R., Hu, L.-Q., Zou, Z.-F., & Si, C.-L.
- Venue
- ACS Sustainable Chemistry & Engineering
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-08-04
- Volume
- 5
- Issue
- 9
- Pages
- 8241-8249
- ISSN
- 2168-0485 (ISSN-L)
- OpenAlex
- W2737373711
- Cited by
- 372
- References
- 4
- FWCI
- 10.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dai, L., Liu, R., Hu, L.-Q., Zou, Z.-F., & Si, C.-L. (2017). Lignin Nanoparticle as a Novel Green Carrier for the Efficient Delivery of Resveratrol. ACS Sustainable Chemistry & Engineering. https://doi.org/10.1021/acssuschemeng.7b01903
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