Intrinsic Disorder and Protein Function

Dunker, A. Keith, Brown, Celeste J., Lawson, J. David, Iakoucheva, Lilia M., Obradović, Zoran·2002·Biochemistry

Cited by (1,001)

Items 101–200 of 1,001

  1. Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases
    Uversky, Vladimir N., Davé, Vrushank, Iakoucheva, Lilia M., Malaney, Prerna, Metallo, Steven J., Pathak, Ravi Ramesh, Joerger, Andreas C. · 2014 · Chemical Reviews
  2. DisProt 7.0: a major update of the database of disordered proteins
    Damiano Piovesan, Francesco Tabaro, Ivan Mičetić, Marco Necci, Federica Quaglia, Christopher J. Oldfield, Maria Cristina Aspromonte, Norman E. Davey, Radoslav S. Davidović, Zsuzsanna Dosztányi et al. · 2016 · Nucleic Acids Research
  3. The alphabet of intrinsic disorder
    François‐Xavier Theillet, Lajos Kalmár, Péter Tompa, Kyou‐Hoon Han, Philipp Selenko, A. Keith Dunker, Gary W. Daughdrill, Vladimir Nikolaevich Uversky · 2013 · Intrinsically Disordered Proteins
  4. Intrinsically unstructured proteins evolve by repeat expansion
    Péter Tompa · 2003 · BioEssays
  5. Unfoldomics of human diseases: linking protein intrinsic disorder with diseases
    Vladimir Nikolaevich Uversky, Christopher J. Oldfield, Uros Midic, Hongbo Michael Xie, Bin Xue, Slobodan Vučetić, Lilia M. Iakoucheva, Zoran Obradovic A, A. Keith Dunker · 2009 · BMC Genomics
  6. Intrinsically disordered proteins as crucial constituents of cellular aqueous two phase systems and coacervates
    Vladimir Nikolaevich Uversky, Irina М. Kuznetsova, Туроверов Константин Константинович, Boris Y. Zaslavsky · 2014 · FEBS Letters
  7. Molecular Principles of the Interactions of Disordered Proteins
    Bálint Mészáros, Péter Tompa, István Simon, Zsuzsanna Dosztányi · 2007 · Journal of Molecular Biology
  8. Functional aspects of protein flexibility
    Kaare Teilum, Johan Gotthardt Olsen, Birthe Brandt Kragelund · 2009 · Cellular and Molecular Life Sciences
  9. Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter
    A. Darling, V. Uversky · 2018 · Frontiers in Genetics
  10. Kinetic Advantage of Intrinsically Disordered Proteins in Coupled Folding–Binding Process: A Critical Assessment of the “Fly-Casting” Mechanism
    Yongqi Huang, Zhirong Liu · 2009 · Journal of Molecular Biology
  11. The Mysterious Unfoldome: Structureless, Underappreciated, Yet Vital Part of Any Given Proteome
    Vladimir Nikolaevich Uversky · 2009 · BioMed Research International
  12. Intrinsic Protein Disorder, Amino Acid Composition, and Histone Terminal Domains
    Jeffrey C. Hansen, Xu Lu, Eric D. Ross, Robert W. Woody · 2005 · Journal of Biological Chemistry
  13. Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes
    Vladimir Nikolaevich Uversky · 2010 · Chemical Society Reviews
  14. Close encounters of the third kind: disordered domains and the interactions of proteins
    Péter Tompa, Mónika Fuxreiter, Christopher J. Oldfield, István Simon, A. Keith Dunker, Vladimir Nikolaevich Uversky · 2009 · BioEssays
  15. The nsp9 Replicase Protein of SARS-Coronavirus, Structure and Functional Insights
    Geoff C. Sutton, Elizabeth E. Fry, Lester G. Carter, Sarah Sainsbury, Tom Walter, Joanne E. Nettleship, Nicholas Simon Berrow, Raymond J. Owens, Robert J.C. Gilbert, Andrew D. Davidson et al. · 2004 · Structure
  16. Functional Anthology of Intrinsic Disorder. 2. Cellular Components, Domains, Technical Terms, Developmental Processes, and Coding Sequence Diversities Correlated with Long Disordered Regions
    Slobodan Vučetić, Hongbo Michael Xie, Lilia M. Iakoucheva, Christopher J. Oldfield, A. Keith Dunker, Zoran Obradovic A, Vladimir Nikolaevich Uversky · 2007 · Journal of Proteome Research
  17. Myelin basic protein—diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis
    George Harauz, Noboru Ishiyama, Christopher M.D Hill, Ian R. Bates, David S. Libich, Christophe Farès · 2004 · Micron
  18. Allostery and Intrinsic Disorder Mediate Transcription Regulation by Conditional Cooperativity
    Abel Garcia‐Pino, Sreeram Balasubramanian, Lode Wyns, Ehud Gazit, Henri De Greve, Roy David Magnuson, Daniël Charlier, Nico A. J. van Nuland, Remy Loris · 2010 · Cell
  19. Assemblages: Functional units formed by cellular phase separation
    Jeffrey A. Toretsky, Peter E. Wright · 2014 · The Journal of Cell Biology
  20. Structural basis for protein phosphatase 1 regulation and specificity
    Wolfgang Peti, Angus Clark Nairn, Rebecca Page · 2012 · FEBS Journal
  21. Intrinsically Disordered Proteins: An Overview
    Rakesh Trivedi, Hampapathalu Adimurthy Nagarajaram · 2022 · International Journal of Molecular Sciences
  22. Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods
    Janita Thusberg, Mauno Vihinen · 2009 · Human Mutation
  23. Prediction of disordered regions in proteins based on the meta approach
    Takashi Ishida, Kengo Kinoshita · 2008 · Bioinformatics
  24. Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase
    Angelo Fontana, Barbara Spolaore, Anna Mero, Francesco Maria Veronese · 2007 · Advanced Drug Delivery Reviews
  25. Rational drug design via intrinsically disordered protein
    Yugong Cheng, Tanguy LeGall, Christopher J. Oldfield, James P. Mueller, Ya-Yue J. Van, Pedro R Romero, Marc S. Cortese, Vladimir Nikolaevich Uversky, A. Keith Dunker · 2006 · Trends in biotechnology
  26. Regulation of Cell Division by Intrinsically Unstructured Proteins: Intrinsic Flexibility, Modularity, and Signaling Conduits
    Charles A. Galea, Yuefeng Wang, Sivashankar G. Sivakolundu, Richard W. Kriwacki · 2008 · Biochemistry
  27. Nickel impact on human health: An intrinsic disorder perspective
    Barbara Zambelli, Vladimir Nikolaevich Uversky, Stefano Ciurli · 2016 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  28. Fuzzy Complexes: A More Stochastic View of Protein Function
    Fuxreiter, Monika, Tompa, Peter · 2012 · Advances in Experimental Medicine and Biology
  29. DisProt: a database of protein disorder
    Slobodan Vučetić, Zoran Obradovic A, Vladimir Vacic, Predrag Radivojac A, Kang Peng, Lilia M. Iakoucheva, Marc S. Cortese, J. David Lawson, Celeste J. Brown, Jason G. Sikes et al. · 2004 · Bioinformatics
  30. Intrinsic disorder in proteins associated with neurodegenerative diseases
    N. Vladimir · 2009 · Frontiers in bioscience
  31. Temperature‐dependent structural changes in intrinsically disordered proteins: Formation of α‒helices or loss of polyproline II?
    Magnus Kjærgaard, Ann‒Beth Nørholm, Ruth Hendus-Altenburger, Stine F. Pedersen, Flemming M. Poulsen, Birthe Brandt Kragelund · 2010 · Protein Science
  32. The role of disorder in interaction networks: a structural analysis
    Philip M. Kim, Andrea Sboner, Yu Xia, Mark Gerstein · 2008 · Molecular Systems Biology
  33. Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations
    Lavery, Derek N., Mcewan, Iain J. · 2005 · Biochemical Journal
  34. Interaction of the Molecular Chaperone αB-Crystallin with α-Synuclein: Effects on Amyloid Fibril Formation and Chaperone Activity
    Agata Rekas, Christopher G. Adda, J. Andrew Aquilina, Kevin Jeffrey Barnham, Margaret Sunde, Denise Galatis, Nicholas A. Williamson, Colin Louis Masters, Robin F. Anders, Carol V. Robinson et al. · 2004 · Journal of Molecular Biology
  35. Comparative analysis of polyphenol oxidase from plant and fungal species
    Carrie M. Marusek, Nicole M. Trobaugh, William H. Flurkey, Jennifer K. Inlow · 2005 · Journal of Inorganic Biochemistry
  36. Intrinsically disordered proteins play diverse roles in cell signaling
    Bondos, Sarah E., Dunker, A. Keith, Uversky, Vladimir N. · 2022 · Cell Communication and Signaling
  37. Methionine oxidation inhibits fibrillation of human α‐synuclein in vitro
    Vladimir Nikolaevich Uversky, Ghiam Yamin, Pierre O. Souillac, John W.F. Goers, Charles B. Glaser, Anthony L. Fink · 2002 · FEBS Letters
  38. Describing intrinsically disordered proteins at atomic resolution by NMR
    Malene Ringkjøbing Jensen, Rob W. H. Ruigrok, Martin J Blackledge · 2013 · Current Opinion in Structural Biology
  39. Distinct circular dichroism spectroscopic signatures of polyproline II and unordered secondary structures: Applications in secondary structure analyses
    José Luiz de Souza Lopes, Andrew John Miles, Lee Whitmore, Bonnie Ann Wallace · 2014 · Protein Science
  40. Conditionally and Transiently Disordered Proteins: Awakening Cryptic Disorder To Regulate Protein Function
    Ursula Jakob, Richard W. Kriwacki, Vladimir Nikolaevich Uversky · 2014 · Chemical Reviews
  41. The protein kingdom extended: Ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation
    Туроверов Константин Константинович, Irina М. Kuznetsova, Vladimir Nikolaevich Uversky · 2010 · Progress in Biophysics and Molecular Biology
  42. Root of the Tree: The Significance, Evolution, and Origins of the Ribosome
    Bowman, Jessica C., Petrov, Anton S., Frenkel-Pinter, Moran, Penev, Petar I., Williams, Loren Dean · 2020 · Chemical Reviews
  43. Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences
    Gian Gaetano Tartaglia, Andrea Cavalli, Riccardo Pellarin, Amedeo Caflisch · 2005 · Protein Science
  44. Accurate Prediction of Protein Disordered Regions by Mining Protein Structure Data
    Jianlin Jack Cheng, Michael J. Sweredoski, Pierre Baldi · 2005 · Data Mining and Knowledge Discovery
  45. Dancing Protein Clouds: The Strange Biology and Chaotic Physics of Intrinsically Disordered Proteins
    Vladimir Nikolaevich Uversky · 2016 · Journal of Biological Chemistry
  46. Intrinsic disorder in measles virus nucleocapsids
    Malene Ringkjøbing Jensen, Guillaume Communie, Euripedes A. Ribeiro, Nicolás Martínez, Ambroise Desfosses, Loïc Salmon, Luca Mollica, Frank Gabel, Marc Jamin, Sonia Longhi et al. · 2011 · Proceedings of the National Academy of Sciences
  47. Quantitative Description of Backbone Conformational Sampling of Unfolded Proteins at Amino Acid Resolution from NMR Residual Dipolar Couplings
    Gabrielle Nodet, Loïc Salmon, Valéry Ozenne, Sebastián Meier, Malene Ringkjøbing Jensen, Martin J Blackledge · 2009 · Journal of the American Chemical Society
  48. Role of Backbone−Solvent Interactions in Determining Conformational Equilibria of Intrinsically Disordered Proteins
    Hoang T. Tran, Albert H. Mao, Rohit V. Pappu · 2008 · Journal of the American Chemical Society
  49. SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins
    Ana Traven, Jörg Heierhorst · 2005 · BioEssays
  50. Structural Models of Amyloid‐Like Fibrils
    Rebecca A. Nelson, David S Eisenberg · 2006 · Advances in protein chemistry
  51. Protein Folding−Simulation
    Valerie Daggett · 2006 · Chemical Reviews
  52. Common principles in clathrin-mediated sorting at the Golgi and the plasma membrane
    Linton M. Traub · 2005 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  53. Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling
    Veronika Csizmók, Ariele Viacava Follis, Richard W. Kriwacki, Julie Deborah Forman-Kay · 2016 · Chemical Reviews
  54. Structural Disorder in Viral Proteins
    Bin Xue, David Blocquel, Johnny Habchi, Alexey V. Uversky, Lukasz Kurgan, Vladimir Nikolaevich Uversky, Sonia Longhi · 2014 · Chemical Reviews
  55. GRAS proteins: the versatile roles of intrinsically disordered proteins in plant signalling
    Xiaolin Sun, William T. Jones, Erik H. A. Rikkerink · 2012 · Biochemical Journal
  56. Intrinsically disordered regions as affinity tuners in protein–DNA interactions
    Dana Vuzman, Yaakov Levy · 2011 · Molecular BioSystems
  57. Comparing Models of Evolution for Ordered and Disordered Proteins
    Celeste J. Brown, Anna Kerr Johnson, Gary W. Daughdrill · 2009 · Molecular Biology and Evolution
  58. Systematic Targeting of Protein–Protein Interactions
    Modell, Ashley E., Blosser, Sarah L., Arora, Paramjit S. · 2016 · Trends in Pharmacological Sciences
  59. iMethyl-PseAAC: Identification of Protein Methylation Sites via a Pseudo Amino Acid Composition Approach
    Wang‐Ren Qiu, Xuan Xiao, Wei‐Zhong Lin, Kuo‐Chen Chou · 2014 · BioMed Research International
  60. Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin43 Indicates Signaling between Binding Domains for c-Src and Zonula Occludens-1
    Paul L. Sorgen, Heather S. Duffy, Prangya Paramita Sahoo, Wanda Coombs, Mario Delmar, David Conover Spray · 2004 · Journal of Biological Chemistry
  61. Liquid–Liquid Phase Separation by Intrinsically Disordered Protein Regions of Viruses: Roles in Viral Life Cycle and Control of Virus–Host Interactions
    Stefania Brocca, Rita Grandori, Sonia Longhi, Vladimir Nikolaevich Uversky · 2020 · International Journal of Molecular Sciences
  62. Promiscuity as a functional trait: intrinsically disordered regions as central players of interactomes
    Alexander Cumberworth, Guillaume Lamour, M. Madan Babu, Jörg A. Gsponer · 2013 · Biochemical Journal
  63. Exploring the binding diversity of intrinsically disordered proteins involved in one‐to‐many binding
    Wei-Lun Hsu, Christopher J. Oldfield, Bin Xue, Jingwei Meng, Fei Huang, Pedro R Romero, Vladimir Nikolaevich Uversky, A. Keith Dunker · 2012 · Protein Science
  64. p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure–Function Continuum Concept
    Vladimir Nikolaevich Uversky · 2016 · International Journal of Molecular Sciences
  65. Alternative splicing and the evolution of phenotypic novelty
    Stephen J. Bush, Lu Chen, Jaime M. Tovar-Corona, Araxi O. Urrutia · 2016 · Philosophical Transactions of the Royal Society B Biological Sciences
  66. Natively Disordered Proteins
    Gary W. Daughdrill, Gary J. Pielak, Vladimir Nikolaevich Uversky, Marc S. Cortese, A. Keith Dunker · 2005 · Wiley eBooks
  67. Protein flexibility and rigidity predicted from sequence
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  68. Advantages of proteins being disordered
    Zhi-Rong Liu, Yong-Qi Huang · 2014 · Protein Science
  69. Amyloidogenesis of Natively Unfolded Proteins
    Vladimir Nikolaevich Uversky · 2008 · Current Alzheimer Research
  70. Small Heat‐shock Proteins and Clusterin: Intra‐ and Extracellular Molecular Chaperones with a Common Mechanism of Action and Function?
    John A. Carver, Agata Rekas, David C. Thorn, Mark R. Wilson · 2003 · IUBMB Life
  71. A functionally required unfoldome from the plant kingdom: intrinsically disordered N-terminal domains of GRAS proteins are involved in molecular recognition during plant development
    Xiaolin Sun, Bin Xue, William T. Jones, Erik H. A. Rikkerink, A. Keith Dunker, Vladimir Nikolaevich Uversky · 2011 · Plant Molecular Biology
  72. AlphaFold2: A Role for Disordered Protein/Region Prediction?
    Wilson, Carter J., Choy, Wing-Yiu, Karttunen, Mikko · 2022 · International Journal of Molecular Sciences
  73. Functional advantages of dynamic protein disorder
    Rebecca B. Berlow, H. Jane Dyson, Peter E. Wright · 2015 · FEBS Letters
  74. Metal ions as modulators of protein conformation and misfolding in neurodegeneration
    Sónia S. Leal, Hugo M. Botelho, Cláudio M. Gomes · 2012 · Coordination Chemistry Reviews
  75. Comprehensive review of methods for prediction of intrinsic disorder and its molecular functions
    Fanchi Meng, Vladimir Nikolaevich Uversky, Lukasz Kurgan · 2017 · Cellular and Molecular Life Sciences
  76. Structural disorder and modular organization in Paramyxovirinae N and P
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  77. Analysis of Ordered and Disordered Protein Complexes Reveals Structural Features Discriminating Between Stable and Unstable Monomers
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  78. Binding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and Experiment
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  79. The roles of intrinsic disorder in protein interaction networks
    Vladimir Nikolaevich Uversky · 2013 · The biomedical & life sciences collection.
  80. Expanding the proteome: disordered and alternatively folded proteins
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  81. High-throughput prediction of RNA, DNA and protein binding regions mediated by intrinsic disorder
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  82. Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP
    Magnus Kjærgaard, Kaare Teilum, Flemming M. Poulsen · 2010 · Proceedings of the National Academy of Sciences
  83. Multifarious Roles of Intrinsic Disorder in Proteins Illustrate Its Broad Impact on Plant Biology
    Xiaolin Sun, Erik H. A. Rikkerink, William T. Jones, Vladimir Nikolaevich Uversky · 2013 · The Plant Cell
  84. Intrinsic Disorder in the Protein Data Bank
    Tanguy LeGall, Pedro R Romero, Marc S. Cortese, Vladimir Nikolaevich Uversky, A. Keith Dunker · 2007 · Journal of Biomolecular Structure and Dynamics
  85. POTENCI: prediction of temperature, neighbor and pH-corrected chemical shifts for intrinsically disordered proteins
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  86. Evolutionary genetics of vertebrate tissue mineralization: the origin and evolution of the secretory calcium‐binding phosphoprotein family
    Kazuhiko Kawasaki, Kenneth M. Weiss · 2005 · Journal of Experimental Zoology Part B Molecular and Developmental Evolution
  87. Nitration inhibits fibrillation of human α‐synuclein in vitro by formation of soluble oligomers
    Ghiam Yamin, Vladimir Nikolaevich Uversky, Anthony L. Fink · 2003 · FEBS Letters
  88. Archaic chaos: intrinsically disordered proteins in Archaea
    Bin Xue, Robert W Williams, Christopher J. Oldfield, A. Keith Dunker, Vladimir Nikolaevich Uversky · 2010 · BMC Systems Biology
  89. Accurate prediction of disorder in protein chains with a comprehensive and empirically designed consensus
    Xiao Fan, Lukasz Kurgan · 2013 · Journal of Biomolecular Structure and Dynamics
  90. Molecular recognition features (MoRFs) in three domains of life
    Jing Ru Yan, A. Keith Dunker, Vladimir Nikolaevich Uversky, Lukasz Kurgan · 2015 · Molecular BioSystems
  91. A comprehensive review and comparison of existing computational methods for intrinsically disordered protein and region prediction
    Yumeng Liu, Xiaolong Wang, Bin Liu · 2017 · Briefings in Bioinformatics
  92. Natively Disordered Proteins
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  93. Casein Proteins as Molecular Chaperones
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  94. Role of naturally occurring osmolytes in protein folding and stability
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  95. Comprehensive large-scale assessment of intrinsic protein disorder
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  96. A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome
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  97. Disease-Associated Mutations Disrupt Functionally Important Regions of Intrinsic Protein Disorder
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  98. Polymer Models of Protein Stability, Folding, and Interactions
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  99. PROFbval: predict flexible and rigid residues in proteins
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  100. Role of intrinsic disorder in transient interactions of hub proteins
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