Intrinsic Disorder and Protein Function

Cited by (1,001)

Items 301–400 of 1,001

1. Intrinsically disordered proteins in crowded milieu: when chaos prevails within the cellular gumbo
   Alexander V. Fonin, April L. Darling, Irina М. Kuznetsova, Туроверов Константин Константинович, Vladimir Nikolaevich Uversky · 2018 · Cellular and Molecular Life Sciences
2. High Affinity Interaction with Filamin A Protects against Calcium-sensing Receptor Degradation
   Mingliang Zhang, Gerda E. Breitwieser · 2005 · Journal of Biological Chemistry
3. Mimicking the Plant Cell Interior under Water Stress by Macromolecular Crowding: Disordered Dehydrin Proteins Are Highly Resistant to Structural Collapse
   Jean‐Marie Mouillon, Sylvia K. Eriksson, Pia Harryson · 2008 · PLANT PHYSIOLOGY
4. Ligand Clouds around Protein Clouds: A Scenario of Ligand Binding with Intrinsically Disordered Proteins
   Fan Jin, Yu Chen, Luhua Lai, Zhirong Liu · 2013 · PLoS Computational Biology
5. Nuclear transport receptor binding avidity triggers a self-healing collapse transition in FG-nucleoporin molecular brushes
   Rafael L. Schoch, Larisa E. Kapinos, Roderick Y. H. Lim · 2012 · Proceedings of the National Academy of Sciences
6. Prediction of Protein Domain with mRMR Feature Selection and Analysis
   Biqing Li, Le‐Le Hu, Lei Chen, Kaiyan Feng, Yu‐Dong Cai, Kuo‐Chen Chou · 2012 · PLoS ONE
7. The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein Arf
   Barbara Mouratou, Valérie Biou, Alexandra Joubert, Jean Cohen, David J. Shields, Niko Geldner, Gerd Jürgens, Paul Melançon, Jacqueline Cherfils · 2005 · BMC Genomics
8. Modularity of intrinsic disorder in the human proteome
   Melissa M. Pentony, David T. Jones · 2009 · Proteins Structure Function and Bioinformatics
9. A comprehensive overview of computational protein disorder prediction methods
   Xin Deng, Jesse Eickholt, Jianlin Jack Cheng · 2011 · Molecular BioSystems
10. Multiscale Ensemble Modeling of Intrinsically Disordered Proteins: p53 N-Terminal Domain
    Tsuyoshi Terakawa, Shoji Takada · 2011 · Biophysical Journal
11. Disease mutations in disordered regions—exception to the rule?
    Vladimir Vacic, Lilia M. Iakoucheva · 2011 · Molecular BioSystems
12. A Mass-Spectrometry-Based Framework To Define the Extent of Disorder in Proteins
    Rebecca Beveridge, Sam Covill, Kamila J. Pacholarz, Jason M. D. Kalapothakis, Cait E. MacPhee, Perdita E. Barran · 2014 · Analytical Chemistry
13. Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators
    Vladimir Nikolaevich Uversky · 2014 · Frontiers in Molecular Biosciences
14. Towards a robust description of intrinsic protein disorder using nuclear magnetic resonance spectroscopy
    Robert C. Schneider, Jie‐rong Huang, Mingxi Yao, Guillaume Communie, Valéry Ozenne, Luca Mollica, Loïc Salmon, Malene Ringkjøbing Jensen, Martin J Blackledge · 2011 · Molecular BioSystems
15. Functional Analysis of Human Hub Proteins and Their Interactors Involved in the Intrinsic Disorder-Enriched Interactions
    Gang Hu, Zhonghua Wu, Vladimir Nikolaevich Uversky, Lukasz Kurgan · 2017 · International Journal of Molecular Sciences
16. Comparative Genomics of DNA Fragments from Six Antarctic Marine Planktonic Bacteria
    Joseph J. Grzymski, Brandon J. Carter, Edward F. DeLong, Robert A. Feldman, Amir Ghadiri, Alison E. Murray · 2006 · Applied and Environmental Microbiology
17. Structure and dynamics of a molten globular enzyme
    Konstantin V. Pervushin, Katherina Vamvaca, Beat Vögeli, Donald Hilvert · 2007 · Nature Structural & Molecular Biology
18. A review of protein structure and gene organisation for proteins associated with mineralised tissue and calcium phosphate stabilisation encoded on human chromosome 4
    N. Laila Huq, Keith J. Cross, Men Ung, Eric Charles Reynolds · 2005 · Archives of Oral Biology
19. Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome
    Peter Tsvetkov, Gad Asher, Aviv Paz, Nina Bacher Reuven, Joel L. Sussman, Israel Silman, Yosef Shaul · 2007 · Proteins Structure Function and Bioinformatics
20. UreG, a Chaperone in the Urease Assembly Process, Is an Intrinsically Unstructured GTPase That Specifically Binds Zn2+
    Barbara Zambelli, Massimiliano Stola, Francesco Musiani, Kris De Vriendt, Bart Samyn, Bart V. Devreese, Jozef VAN BEEUMEN, Paola Turano, Alexander Dikiy, Donald A. Bryant et al. · 2004 · Journal of Biological Chemistry
21. Chromatin Condensing Functions of the Linker Histone C-Terminal Domain Are Mediated by Specific Amino Acid Composition and Intrinsic Protein Disorder
    Xu Lu, Barbara A. Hamkalo, Missag Hagop Parseghian, Jeffrey C. Hansen · 2008 · Biochemistry
22. Visualization of Intrinsically Disordered Regions of Proteins by High‐Speed Atomic Force Microscopy
    Atsushi Miyagi, Yasuo Tsunaka, Takayuki Uchihashi, Kouta Mayanagi, Susumu Hirose, Kosuke Morikawa, Toshio Ando · 2008 · ChemPhysChem
23. Calmodulin signaling: Analysis and prediction of a disorder‐dependent molecular recognition
    Predrag Radivojac A, Slobodan Vučetić, Timothy R. O'Connor, Vladimir Nikolaevich Uversky, Zoran Obradovic A, A. Keith Dunker · 2006 · Proteins Structure Function and Bioinformatics
24. Measuring the Evolutionary Rewiring of Biological Networks
    Chong Shou, Nitin Bhardwaj, Hugo Y. K. Lam, Koon‐Kiu Yan, Philip M. Kim, Michael P. Snyder, Mark Gerstein · 2011 · PLoS Computational Biology
25. Protein disorder prediction by condensed PSSM considering propensity for order or disorder
    Chung-Tsai Su, Chien‐Yu Chen, Yu‐Yen Ou · 2006 · BMC Bioinformatics
26. Intrinsically Disordered Regions of Human Plasma Membrane Proteins Preferentially Occur in the Cytoplasmic Segment
    Yoshiaki Minezaki, Keiichi Homma, Ken Nishikawa · 2007 · Journal of Molecular Biology
27. The O-Glycosylated Linker from the Trichoderma reesei Family 7 Cellulase Is a Flexible, Disordered Protein
    Gregg T. Beckham, Yannick J. Bomble, James F. Matthews, Courtney B. Taylor, Michael G. Resch, John M. Yarbrough, Stephen R. Decker, Lintao Bu, Xiongce Zhao, Clare McCabe et al. · 2010 · Biophysical Journal
28. The Ambivalent Role of Proline Residues in an Intrinsically Disordered Protein: From Disorder Promoters to Compaction Facilitators
    Borja Mateos, Clara Conrad‐Billroth, Marco Schiavina, Andreas Beier, Georg Kontaxis, Robert Konrat, Isabella C. Felli, Roberta Pierattelli · 2019 · Journal of Molecular Biology
29. Tubulin Polymerization Promoting Proteins (TPPPs): Members of a New Family with Distinct Structures and Functions
    Orsolya Vincze, Natália Tőkési, Judit Oláh, Emma Hlavanda, Ágnes Zotter, István Horváth, Attila Lehotzky, László Tirián, Katalin F. Medzihradszky, János Kovács et al. · 2006 · Biochemistry
30. Limitations of Induced Folding in Molecular Recognition by Intrinsically Disordered Proteins
    Eszter Házy, Péter Tompa · 2009 · ChemPhysChem
31. Targeting intrinsically disordered proteins in rational drug discovery
    Susmitha Ambadipudi, Markus Zweckstetter · 2015 · Expert Opinion on Drug Discovery
32. Primary Contact Sites in Intrinsically Unstructured Proteins: The Case of Calpastatin and Microtubule-Associated Protein 2
    Veronika Csizmók, M. Bokor, Péter Bánki, Éva Klement, Katalin F. Medzihradszky, Péter Friedrich, Kalman Tompa, Péter Tompa · 2005 · Biochemistry
33. Polyanions and the Proteome
    LaToya S. Jones, Brian Yazzie, Charles Russell Middaugh · 2004 · Molecular & Cellular Proteomics
34. Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1
    Julie S. Barber-Rotenberg, Saravana P. Selvanathan, Yali Kong, Hayriye Verda Erkizan, Tara M. Snyder, S. Peter Hong, Christina L. Kobs, Natalie L. South, Steven Summer, Philip J. Monroe et al. · 2012 · Oncotarget
35. Intrinsic Disorder-Based Emergence in Cellular Biology: Physiological and Pathological Liquid-Liquid Phase Transitions in Cells
    April L. Darling, Boris Y. Zaslavsky, Vladimir Nikolaevich Uversky · 2019 · Polymers
36. Dynamic Behavior of an Intrinsically Unstructured Linker Domain Is Conserved in the Face of Negligible Amino Acid Sequence Conservation
    Gary W. Daughdrill, Pranesh Narayanaswami, Sara H. Gilmore, Agniezka Belczyk, Celeste J. Brown · 2007 · Journal of Molecular Evolution
37. Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor
    Anna S. Garza, Shagufta H. Khan, Praveen Kumar · 2009 · Molecular and Cellular Biology
38. PreDisorder: ab initio sequence-based prediction of protein disordered regions
    Xin Deng, Jesse Eickholt, Jianlin Jack Cheng · 2009 · BMC Bioinformatics
39. Kinase regulation by liquid–liquid phase separation
    Tania P. López-Palacios, Joshua Lyon Andersen · 2022 · Trends in Cell Biology
40. Structural characterization of intrinsically disordered proteins by the combined use of NMR and SAXS
    Nathalie Sibille, Pau Bernadó · 2012 · Biochemical Society Transactions
41. Functional classification of scaffold proteins and related molecules
    László Buday, Péter Tompa · 2010 · FEBS Journal
42. Cell-cycle-dependent phosphorylation of the nuclear pore Nup107–160 subcomplex
    Joseph S. Glavy, Andrew N. Krutchinsky, Ileana M. Cristea, Ian C. Berke, Thomas Boehmer, Günter Blobel, Brian T. Chait · 2007 · Proceedings of the National Academy of Sciences
43. Roles of intrinsic disorder in protein–nucleic acid interactions
    H. Jane Dyson · 2011 · Molecular BioSystems
44. Library of Disordered Patterns in 3D Protein Structures
    Michail Yu. Lobanov, Е.И. Фурлетова, Natalya S. Bogatyreva, Ройтберг Михаил Абрамович, Oxana V. Galzitskaya · 2010 · PLoS Computational Biology
45. Application of molecular dynamic simulation to study food proteins: A review
    Ashutosh Singh, Sai Kranthi Vanga, Valérie Orsat, Vijaya Raghavan · 2017 · Critical Reviews in Food Science and Nutrition
46. The role of disorder in RNA binding affinity and specificity
    Diana S. M. Ottoz, Luke E. Berchowitz · 2020 · Open Biology
47. Multiparametric Analysis of Intrinsically Disordered Proteins: Looking at Intrinsic Disorder through Compound Eyes
    Vladimir Nikolaevich Uversky, A. Keith Dunker · 2011 · Analytical Chemistry
48. Dnmt1
    Željko M. Svedružić · 2011 · Progress in molecular biology and translational science
49. The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing
    Qing Fang, Artur A. Indzhykulian, Mirna Mustapha, Gavin P. Riordan, David F. Dolan, Thomas B. Friedman, Inna A. Belyantseva, Gregory I. Frolenkov, Sally Ann Camper, Jonathan E. Bird · 2015 · eLife
50. Structural Characterization of the Native NH2-Terminal Transactivation Domain of the Human Androgen Receptor: A Collapsed Disordered Conformation Underlies Structural Plasticity and Protein-Induced Folding
    Derek N. Lavery, Iain J. McEwan · 2008 · Biochemistry
51. Evaluation of disorder predictions in CASP5
    Eugene Melamud, John Moult · 2003 · Proteins Structure Function and Bioinformatics
52. Atomistic Details of the Disordered States of KID and pKID. Implications in Coupled Binding and Folding
    Debabani Ganguly, Jianhan Chen · 2009 · Journal of the American Chemical Society
53. Biological importance of arginine: A comprehensive review of the roles in structure, disorder, and functionality of peptides and proteins
    Munishwar Nath Gupta, Vladimir Nikolaevich Uversky · 2023 · International Journal of Biological Macromolecules
54. Structural disorder within the replicative complex of measles virus: Functional implications
    Jean‐Marie Bourhis, Bruno Canard, Sonia Longhi · 2005 · Virology
55. Classification and knowledge discovery in protein databases
    Predrag Radivojac A, Nitesh V. Chawla, A. Keith Dunker, Zoran Obradovic A · 2004 · Journal of Biomedical Informatics
56. Multi-functionality of proteins involved in GPCR and G protein signaling: making sense of structure–function continuum with intrinsic disorder-based proteoforms
    Fonin, Alexander V., Darling, April L., Kuznetsova, Irina M., Turoverov, Konstantin K., Uversky, Vladimir N. · 2019 · Cellular and Molecular Life Sciences
57. Multifunctionality of the linker histones: an emerging role for protein-protein interactions
    Steven J. McBryant, Xu Lu, Jeffrey C. Hansen · 2010 · Cell Research
58. The transition state structure for coupled binding and folding of disordered protein domains
    Jakob Dogan, Xin Ni Mu, Åke Engström, Per Jemth · 2013 · Scientific Reports
59. CSpritz: accurate prediction of protein disorder segments with annotation for homology, secondary structure and linear motifs
    Ian Walsh, Alberto J. M. Martín, Tomás Di Domenico, Alessandro Vullo, Gianluca Pollastri, Silvio C. E. Tosatto · 2011 · Nucleic Acids Research
60. Modeling protein association mechanisms and kinetics
    Huan‐Xiang Zhou, Paul A. Bates · 2013 · Current Opinion in Structural Biology
61. Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation
    Zhou, Jianhong, Zhao, Suwen, Dunker, A. Keith · 2018 · Journal of Molecular Biology
62. The triple power of D³: Protein intrinsic disorder in degenerative diseases
    Vladimir Nikolaevich Uversky · 2014 · Frontiers in bioscience
63. Mapping Residual Structure in Intrinsically Disordered Proteins at Residue Resolution Using Millisecond Hydrogen/Deuterium Exchange and Residue Averaging
    Theodore R. Keppel, David D. Weis · 2014 · Journal of the American Society for Mass Spectrometry
64. Intrinsically Disordered p53 Extreme C-Terminus Binds to S100B(ββ) through “Fly-Casting”
    Jianhan Chen · 2009 · Journal of the American Chemical Society
65. A distinct structural region of the prokaryotic ubiquitin‐like protein (Pup) is recognized by the N‐terminal domain of the proteasomal ATPase Mpa
    Markus Sutter, Frank Striebel, Fred Franz Damberger, Frédéric H.‐T. Allain, Eilika U. Weber-Ban · 2009 · FEBS Letters
66. DNdisorder: predicting protein disorder using boosting and deep networks
    Jesse Eickholt, Jianlin Jack Cheng · 2013 · BMC Bioinformatics
67. Mapping Unstructured Regions and Synergistic Folding in Intrinsically Disordered Proteins with Amide H/D Exchange Mass Spectrometry
    Theodore R. Keppel, Brent A. Howard, David D. Weis · 2011 · Biochemistry
68. Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer?
    Bora Uyar, Robert J. Weatheritt, Holger Dinkel, Norman E. Davey, Toby J. Gibson · 2014 · Molecular BioSystems
69. Phenogenetic drift in evolution: The changing genetic basis of vertebrate teeth
    Kazuhiko Kawasaki, Tohru Suzuki, Kenneth M. Weiss · 2005 · Proceedings of the National Academy of Sciences
70. Protein Disorder Prevails under Crowded Conditions
    Cs. Szasz, Anita Alexa, Katalin Tóth, Marianna Rakács, Jörg Langowski, Péter Tompa · 2011 · Biochemistry
71. DFLpred: High-throughput prediction of disordered flexible linker regions in protein sequences
    Fanchi Meng, Lukasz Kurgan · 2016 · Bioinformatics
72. Fast Association and Slow Transitions in the Interaction between Two Intrinsically Disordered Protein Domains
    Jakob Dogan, Tanja Schmidt, Xin Ni Mu, Åke Engström, Per Jemth · 2012 · Journal of Biological Chemistry
73. N-terminal Domains of DELLA Proteins Are Intrinsically Unstructured in the Absence of Interaction with GID1/Gibberellic Acid Receptors
    Xiaolin Sun, William T. Jones, Dawn Harvey, Patrick J. B. Edwards, Steven M. Pascal, Christopher A. Kirk, Thérèse Considine, David J. Sheerin, Jasna Rakonjac, Christopher J. Oldfield et al. · 2010 · Journal of Biological Chemistry
74. Understanding and identifying amino acid repeats
    H. Luo, Harm Nijveen · 2013 · Briefings in Bioinformatics
75. Computer Simulations of Intrinsically Disordered Proteins
    Song‐Ho Chong, Prathit Chatterjee, Sihyun Ham · 2017 · Annual Review of Physical Chemistry
76. NMR Relaxation Studies on the Hydrate Layer of Intrinsically Unstructured Proteins
    M. Bokor, Veronika Csizmók, Dénes Kovács, Péter Bánki, Péter Friedrich, Péter Tompa, Kalman Tompa · 2004 · Biophysical Journal
77. An equilibrium thermodynamic model of the sequestration of calcium phosphate by casein phosphopeptides
    ElaineM. Little, Carl Holt · 2004 · European Biophysics Journal
78. Intrinsically disordered regions of p53 family are highly diversified in evolution
    Bin Xue, Celeste J. Brown, A. Keith Dunker, Vladimir Nikolaevich Uversky · 2013 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
79. Druggability of Intrinsically Disordered Proteins
    Priyanka Joshi, Michele Vendruscolo · 2015 · Advances in experimental medicine and biology
80. ff14IDPs force field improving the conformation sampling of intrinsically disordered proteins
    Dong Song, Wei Wang, Wei Ye, Dingjue Ji, Ray Luo, Haifeng Chen · 2016 · Chemical Biology & Drug Design
81. Coarse-Grained Potentials for Local Interactions in Unfolded Proteins
    Ali Ghavami, Erik Van der Giessen, Patrick R. Onck · 2012 · Journal of Chemical Theory and Computation
82. Small-angle scattering studies of intrinsically disordered proteins and their complexes
    Tiago N. Cordeiro, Fátima Herranz-Trillo, Annika Urbanek, Alejandro Estaña, Juan Cortés, Nathalie Sibille, Pau Bernadó · 2016 · Current Opinion in Structural Biology
83. Intrinsically Disordered Side of the Zika Virus Proteome
    Rajanish Giri, Deepak Kumar, Nitin Sharma, Vladimir Nikolaevich Uversky · 2016 · Frontiers in Cellular and Infection Microbiology
84. Deletion of a C–terminal intrinsically disordered region of WRINKLED 1 affects its stability and enhances oil accumulation in Arabidopsis
    Wei Ma, Que Kong, Michael Grix, Jenny J. Mantyla, Yang Yang, Christoph Benning A, John B. Ohlrogge · 2015 · The Plant Journal
85. Hemocyanin conformational changes associated with SDS-induced phenol oxidase activation
    Sharon Baird, Sharon M. Kelly, Nicholas C. Price, Elmar Jaenicke, Christian Meesters, Dorothea Nillius, Heinz Decker, Jacqueline Nairn · 2007 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
86. The YefM Antitoxin Defines a Family of Natively Unfolded Proteins
    Izhack Cherny, Ehud Gazit · 2004 · Journal of Biological Chemistry
87. Crystal Structure of the Human CCA-adding Enzyme: Insights into Template-independent Polymerization
    Martin A. Augustin, Andreas S. Reichert, Heike Betat, Robert Huber, Mario Mörl, Clemens Steegborn · 2003 · Journal of Molecular Biology
88. The Angiotensin II AT1Receptor Structure-Activity Correlations in the Light of Rhodopsin Structure
    Laerte Oliveira, Cláudio M. Costa-Neto, Clovis Ryuichi Nakaie, Shirley Schreier, Suma Imura Shimuta, Antonio C.M. Paiva · 2007 · Physiological Reviews
89. In silico structure-based approaches to discover protein-protein interaction-targeting drugs
    Woong‐Hee Shin, Charles W. Christoffer, Daisuke Kihara · 2017 · Methods
90. R120G αB‐crystallin promotes the unfolding of reduced α‐lactalbumin and is inherently unstable
    Teresa M. Treweek, Agata Rekas, Robyn A. Lindner, Mark J. Walker, J. Andrew Aquilina, Carol V. Robinson, Joseph Horwitz, Ming Der Perng, Roy A. Quinlan, John A. Carver · 2005 · FEBS Journal
91. Sequence patterns associated with disordered regions in proteins
    Stefano Lise, David T. Jones · 2004 · Proteins Structure Function and Bioinformatics
92. Disordered RNA chaperone proteins: from functions to disease
    Roland Iványi-Nagy, Laëtitia Davidovic, Edward W. Khandjian, Jean‐Luc Darlix · 2005 · Cellular and Molecular Life Sciences
93. Addressing the intrinsic disorder bottleneck in structural proteomics
    Christopher J. Oldfield, Eldon L. Ulrich, Yugong Cheng, A. Keith Dunker, John L. Markley · 2005 · Proteins Structure Function and Bioinformatics
94. Improving protein order-disorder classification using charge-hydropathy plots
    Fei Huang, Christopher J. Oldfield, Bin Xue, Wei-Lun Hsu, Jingwei Meng, Xiaowen Liu, Li Shen, Pedro R Romero, Vladimir Nikolaevich Uversky, A. Keith Dunker · 2014 · BMC Bioinformatics
95. Natural Disordered Sequences in the Amino Terminal Domain of Nuclear Receptors: Lessons from the Androgen and Glucocorticoid Receptors
    Iain J. McEwan, Derek N. Lavery, Katharina Fischer, Kate Watt · 2007 · Nuclear Receptor Signaling
96. Dissociation from the Oligomeric State Is the Rate-limiting Step in Fibril Formation by κ-Casein
    Heath W. Ecroyd, Tomáš Koudelka, David C. Thorn, Danielle M. Williams, Glyn L. Devlin, Peter Hoffmann, John A. Carver · 2008 · Journal of Biological Chemistry
97. Membrane-anchoring and Charge Effects in the Interaction of Myelin Basic Protein with Lipid Bilayers Studied by Site-directed Spin Labeling
    Ian R. Bates, Joan M. Boggs, Jimmy B. Feix, George Harauz · 2003 · Journal of Biological Chemistry
98. Test and Evaluation of ff99IDPs Force Field for Intrinsically Disordered Proteins
    Wei Ye, Dingjue Ji, Wei Wang, Ray Luo, Haifeng Chen · 2015 · Journal of Chemical Information and Modeling
99. A maximum entropy approach to the study of residue‐specific backbone angle distributions in α‐synuclein, an intrinsically disordered protein
    Alexey B. Mantsyzov, Alexander S. Maltsev, Jinfa Ying, Yang Shen, Gerhard Hummer, Ad Bax · 2014 · Protein Science
100. Competitive recruitment of the periplasmic translocation portal TolB by a natively disordered domain of colicin E9
     Steven R. Loftus, Daniel Walker, María Jesus Maté, Daniel A. Bonsor, Richard James, Geoffrey R. Moore, Colin Kleanthous · 2006 · Proceedings of the National Academy of Sciences