Self-Assembly of Aβ 1 - 42 into Globular Neurotoxins

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Items 301–400 of 518

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4. Role of Intramolecular Aromatic π–π Interactions in the Self‐Assembly of Di‐ l ‐Phenylalanine Dipeptide Driven by Intermolecular Interactions: Effect of Alanine Substitution
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5. Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.
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7. Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification
   Hideko Kokubo, Rakez Kayed, Charles G. Glabe, Matthias Staufenbiel, Takaomi C. Saido, Nobuhisa Iwata, Haruyasu Yamaguchi · 2009 · International Journal of Alzheimer s Disease
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   Ann‐Louise Bergström, Joëlle Chabry, Lone Bastholm, Peter M. H. Heegaard · 2007 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
9. Protein Aggregation Diseases: Toxicity of Soluble Prefibrillar Aggregates and Their Clinical Significance
   Massimo Stefani · 2010 · Methods in molecular biology
10. Gami-Chunghyuldan ameliorates memory impairment and neurodegeneration induced by intrahippocampal Aβ1–42 oligomer injection
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11. Ca2+, within the physiological concentrations, selectively accelerates Aβ42 fibril formation and not Aβ40 in vitro
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12. Inhibition of human prion neuropeptide PrP106-126 aggregation by hexacoordinated ruthenium complexes
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13. Not Oligomers but Amyloids are Cytotoxic in the Membrane‐Mediated Amyloidogenesis of Amyloid‐β Peptides
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14. Targeting soluble amyloid-beta oligomers with a novel nanobody
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15. From Alpha to Omega with Aβ: Targeting the Multiple Molecular Appearances of the Pathogenic Peptide in Alzheimers Disease
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16. Diagnostic effectiveness of quantitative [18F]flutemetamol PET imaging for detection of fibrillar amyloid β using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus
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17. Amyloid-β1–40 Inhibits Amyloid-β1–42 Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Degeneration
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18. Molecules that Disrupt Memory Circuits in Alzheimer’s Disease: The Attack on Synapses by Aβ Oligomers (ADDLs)
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19. Amyloid-β Activates Microglia and Regulates Protein Expression in a Manner Similar to Prions
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20. Globular and Protofibrillar Aβ Aggregates Impair Neurotransmission by Different Mechanisms
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22. Inhibitory effects of NAMI-A-like ruthenium complexes on prion neuropeptide fibril formation
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23. Identification of amyloid-beta 1–42 binding protein fragments by screening of a human brain cDNA library
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24. Cytotoxicity of albebetin oligomers depends on cross‐β‐sheet formation
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25. Ameliorative effects of a non-competitive BACE1 inhibitor TAK-070 on Aβ peptide levels and impaired learning behavior in aged rats.
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26. Targeting disorders in unstructured and structured proteins in various diseases
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27. Self-Assembly of Aβ40, Aβ42 and Aβ43 Peptides in Aqueous Mixtures of Fluorinated Alcohols
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28. Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE−/− mice
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29. Acute effect of β amyloid on synchronized spontaneous Ca2+ oscillations in cultured hippocampal networks
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30. Conductive Hybrid Nanofibers Self-Assembled with Three Different Amphiphilic Salts
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31. Different zinc(II) complex species and binding modes at Aβ N-terminus drive distinct long range cross-talks in the Aβ monomers
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32. Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner
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33. Stability of Aβ (1-42) peptide fibrils as consequence of environmental modifications
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34. Effect of Cinnamomum Verum Extract on the Amyloid Formation of Hen Egg-white Lysozyme and Study of its Possible Role in Alzheimer's Disease.
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35. Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease
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36. Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer’s disease via activation of α7nAChR
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37. Soluble state high resolution atomic force microscopy study of Alzheimer’s β-amyloid oligomers
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38. Inhibition of human amylin aggregation by Flavonoid Chrysin: An in-silico and in-vitro approach
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39. Granular Non-Fibrillar Aggregates and Toxicity in Alzheimer’s Disease
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40. Physiological Aβ Concentrations Produce a More Biomimetic Representation of the Alzheimer’s Disease Phenotype in iPSC Derived Human Neurons
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41. Aβ42 fibril formation from predominantly oligomeric samples suggests a link between oligomer heterogeneity and fibril polymorphism
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42. Intrathecal amyloid‐beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease
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45. The role of metals in amyloid aggregation—Experiments and ab initio simulations
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46. Envisaging the Structural Elevation in the Early Event of Oligomerization of Disordered Amyloid β Peptide
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47. Intracellular Amyloid-β in the Normal Rat Brain and Human Subjects and Its relevance for Alzheimer’s Disease
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48. Antibody 9D5 Recognizes Oligomeric Pyroglutamate Amyloid-β in a Fraction of Amyloid-β Deposits in Alzheimer's Disease without Cross-Reactivity with other Protein Aggregates
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49. Anti-Aβ Oligomer IgG and Surface Sialic Acid in Intravenous Immunoglobulin: Measurement and Correlation with Clinical Outcomes in Alzheimer’s Disease Treatment
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51. Endo- and exocytic budding transformation of slow-diffusing membrane domains induced by Alzheimer's amyloid beta
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52. Diverse Ecdysterones Show Different Effects on Amyloid-β42 Aggregation but All Uniformly Inhibit Amyloid-β42-Induced Cytotoxicity
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55. A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein
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56. Amyloid β peptide-mediated neurotoxicity is attenuated by the proliferating microglia more potently than by the quiescent phenotype
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58. A label-free electrical assay of fibrous amyloid β based on semiconductor biosensing
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61. Characterization of Inter- and Intramolecular Interactions of Amyloid Fibrils by AFM-Based Single-Molecule Force Spectroscopy
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63. Altering APP Proteolysis: Increasing sAPPalpha Production by Targeting Dimerization of the APP Ectodomain
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65. An Essential Role for Alzheimer’s-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis
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66. Physico-chemical methods for studying amyloid-β aggregation
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67. A general strategy for the bacterial expression of amyloidogenic peptides using BCL‐XL‐1/2 fusions
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69. Involvement of SDS-Stable HigherMrForms of Bovine Normal Milk α-Lactalbumin in Inducing Intestinal IEC-6 Cell Death
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71. Fatty Acid Concentration and Phase Transitions Modulate Aβ Aggregation Pathways
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75. Moxifloxacin Disrupts and Attenuates Aβ42 Fibril and Oligomer Formation: Plausibly Repositioning an Antibiotic as Therapeutic against Alzheimer’s Disease
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76. Cudrania cochinchinensis attenuates amyloid β protein-mediated microglial activation and promotes glia-related clearance of amyloid β protein
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83. Nonfibrillar Abeta1–42 Inhibits Glutamate Uptake and Phosphorylates p38 in Human Fibroblasts
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