The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4
Bae, Chilman, Sachs, Frederick, Gottlieb, Philip A.·2011·Biochemistry
Cited by (568)
Items 101–200 of 568
- On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos ChannelsVirgilio L. Lew, Teresa Tiffert · 2017 · Frontiers in Physiology
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- Evidence for shear-mediated Ca2+ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell lineZeki Ilkan, Joy R. Wright, Alison H. Goodall, Jonathan M. Gibbins, Chris Ian Jones, Martyn P. Mahaut‐Smith · 2017 · Journal of Biological Chemistry
- Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeuticsJing Zhang, Zhimin Hu, Calista A. Horta, Jing Yang · 2022 · Seminars in Cancer Biology
- Versatile spider venom peptides and their medical and agricultural applicationsNatalie J. Saez, Volker Herzig · 2018 · Toxicon
- Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis developmentLaura Brylka, Assil‐Ramin Alimy, Miriam Eva Angelica Tschaffon, Shan Jiang, Tobias Malte Ballhause, Anke Baranowsky, Simon V. Kroge, Julian Delsmann, Eva Pawlus, Kian Eghbalian et al. · 2024 · Bone Research
- Piezo1-Mediated Ca2+ Activities Regulate Brain Vascular Pathfinding during DevelopmentTingting Liu, Xu-Fei Du, Baibing Zhang, Huaxing Zi, Yong Yan, Jiang‐An Yin, Han Hou, Shanye Gu, Qi Chen, Jiulin Du · 2020 · Neuron
- Mechanical stress activates NMDA receptors in the absence of agonistsMohammad Mehdi Maneshi, Bruce A. Maki, Radhakrishnan Gnanasambandam, Sophie Belin, Gabriela Popescu, Frederick Sachs, Susan Z. Hua · 2017 · Scientific Reports
- Origin of the ForceCharles David Cox, Navid Bavi, Boris Martinac · 2016 · Current topics in membranes
- Mechanosensitive Piezo Channels in the Gastrointestinal TractConstanza Alcaino, Gianrico Farrugia, Arthur Beyder · 2017 · Current topics in membranes
- Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1Mohammad Mehdi Maneshi, Lynn M. Ziegler, Frederick Sachs, Susan Z. Hua, Philip A. Gottlieb · 2018 · Scientific Reports
- Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 ChannelsJian Shi, Adam J. Hyman, Dario De Vecchis, Jiehan Chong, Laeticia Lichtenstein, Timothy Simon Futers, Myriam Rouahi, Anne Nègre‐Salvayre, Nathalie Augè, Antreas C. Kalli et al. · 2020 · Cell Reports
- Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflowOleg V. Yarishkin, Tam T. T. Phuong, Jackson M. Baumann, Michael Lucio De Ieso, Felix Vázquez-Chona, Christopher N. Rudzitis, Chad A. Sundberg, Mónika Lakk, William Daniel Stamer, David Križaj · 2020 · The Journal of Physiology
- A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cellsYingying Ye, Mohammad Barghouth, Haiqiang Dou, Cheng Luan, Yongzhi Wang, Alexandros Karagiannopoulos, Xiaoping Jiang, Ulrika Krus, Malin Fex, Quan Zhang et al. · 2022 · Nature Communications
- Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytesAlireza Savadipour, Robert J. Nims, Neda Rashidi, Jaquelin M. Garcia‐Castorena, Ruhang Tang, Gabrielle K. Marushack, Sara J. Oswald, Wolfgang Liedtke, Farshid Guilak · 2023 · Proceedings of the National Academy of Sciences
- Tentonin 3/TMEM150c Confers Distinct Mechanosensitive Currents in Dorsal-Root Ganglion Neurons with Proprioceptive FunctionGyu‐Sang Hong, Byeongjun Lee, Jungwon Wee, Hyeyeon Chun, Hyungsup Kim, Jooyoung Jung, Joo Young Cha, Tae‐Ryong Riew, Gyu Hyun Kim, In‐Beom Kim et al. · 2016 · Neuron
- Piezo1 is required for outflow tract and aortic valve developmentAdèle Faucherre, Hamid Moha ou Maati, Nathalie Nasr, Amélie Pinard, Alexis Théron, Gaëlle Odelin, Jean‐Pierre Desvignes, David Salgado, Gwenaëlle Collod‐Béroud, Jean-François Aviérinos et al. · 2019 · Journal of Molecular and Cellular Cardiology
- Functional Expression of Piezo1 in Dorsal Root Ganglion (DRG) NeuronsJueun Roh, Sung-Min Hwang, Sun-Ho Lee, Kihwan Lee, Yong Ho Kim, Chul‐Kyu Park · 2020 · International Journal of Molecular Sciences
- The mechano‐gated channel inhibitor GsMTx4 reduces the exercise pressor reflex in decerebrate ratsSteven W. Copp, Joyce S. Kim, Víctor Ruiz-Velasco, Marc P. Kaufman · 2015 · The Journal of Physiology
- Conductance and block of hair-cell mechanotransducer channels in transmembrane channel–like protein mutantsMaryline Beurg, Kyunghee X. Kim, Robert Fettiplace · 2014 · The Journal of General Physiology
- The mechanosensitive Piezo1 channel: structural features and molecular bases underlying its ion permeation and mechanotransductionYubo Wang, Bailong Xiao · 2017 · The Journal of Physiology
- Electrophysiological-mechanical coupling in the neuronal membrane and its role in ultrasound neuromodulation and general anaesthesiaAntoine Jérusalem, Zeinab Al‐Rekabi, Haoyu Chen, Ari Ercole, Majid Malboubi, Miren Tamayo‐Elizalde, Lennart Verhagen, Sonia Contera · 2019 · Acta Biomaterialia
- Piezo1 and its inhibitors: Overview and perspectivesThien, Nguyen Duc, Hai-Nam, Nguyen, Anh, Duong Tien, Baecker, Daniel · 2024 · European Journal of Medicinal Chemistry
- Piezo channels contribute to the regulation of myelination in Schwann cellsJenica Acheta, Urja Bhatia, Haley Jeanette, Jiayue Hong, Kyle Rich, Rachel Close, Marie E. Bechler, Sophie Belin, Yannick Poitelon · 2022 · Glia
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- Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1Weiyi Qian, Tarik Hadi, Michele Silvestro, Xiao Ma, Cristobal F. Rivera, Apratim Bajpai, Rui Li, Zijing Zhang, Hengdong Qu, Rayan Sleiman Tellaoui et al. · 2022 · Nature Communications
- The role of PIEZO ion channels in the musculoskeletal systemAlireza Savadipour, Daniel Palmer, Erica V. Ely, Kelsey H. Collins, Jaquelin M. Garcia‐Castorena, Zainab Harissa, Yu Seon Kim, Arin Oestrich, Feini Qu, Neda Rashidi et al. · 2023 · American Journal of Physiology-Cell Physiology
- Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4Constanza Alcaino, Kaitlyn R. Knutson, Philip A. Gottlieb, Gianrico Farrugia, Arthur Beyder · 2017 · Channels
- Role of Piezo Channels in Joint Health and InjuryWhasil Lee, Farshid Guilak, Wolfgang Liedtke · 2017 · Current topics in membranes
- Emerging Piezo1 signaling in inflammation and atherosclerosis; a potential therapeutic targetShafiu A. Umar Shinge, Daifang Zhang, Ahmad Ud Din, Fengxu Yu, Yongmei Nie · 2022 · International Journal of Biological Sciences
- Disorders of red cell volume regulationPatrick G. Gallagher · 2013 · Current Opinion in Hematology
- Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swineVictoria E. Cotero, John F. Graf, Hiromi Miwa, Zall Hirschstein, Khaled Qanud, Tomas S. Huerta, Ningwen Tai, Yuyan Ding, Kevin Jimenez-Cowell, Jacquelyn N. Tomaio et al. · 2022 · Nature Biomedical Engineering
- Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous systemBoyi Zong, Fengzhi Yu, Xiaoyou Zhang, Yige Pang, Wenrui Zhao, Peng Sun, Lin Li · 2023 · Ageing Research Reviews
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- Molecular candidates for cardiac stretch-activated ion channelsAlistair J. M. Reed, Peter Karl Kohl, Rémi Peyronnet · 2014 · Global Cardiology Science and Practice
- Human PIEZO1: Removing InactivationChilman Bae, Philip A. Gottlieb, Frederick Sachs · 2013 · Biophysical Journal
- The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microgliaTing Zhu, Jinghui Guo, Yong Wu, Ting Lei, Jiejun Zhu, Hui Chen, Shashwati Kala, Kin Fung Wong, Chi Pong Cheung, Xiaohui Huang et al. · 2023 · iScience
- Piezo1 Channels in Vascular Development and the Sensing of Shear StressAdam J. Hyman, Sarka Tumova, David J. Beech · 2017 · Current topics in membranes
- The spectrin cytoskeleton integrates endothelial mechanoresponsesSivakami Mylvaganam, Jonathan D. Plumb, Bushra Yusuf, Ren Li, Chien-Yi Lu, Lisa Annette Robinson, Spencer A. Freeman, Sergio Grinstein · 2022 · Nature Cell Biology
- Piezo1 and BKCa channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillationDorothee Jakob, Alexander Klesen, Benoit Allegrini, Elisa Darkow, Diana Aria, Ramona Emig, Ana Simón-Chica, Eva A. Rog‐Zielinska, Tim A Guth, Friedhelm Beyersdorf et al. · 2021 · Journal of Molecular and Cellular Cardiology
- Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in miceSandip Madhusudan Swain, Joelle M.-J. Romac, Steven R. Vigna, Rodger A. Liddle · 2022 · JCI Insight
- Cell Mechanotransduction With Piconewton Forces Applied by Optical TweezersFabio Falleroni, Vincent Torre, Dan Cojoc · 2018 · Frontiers in Cellular Neuroscience
- Identification of PIEZO1 as a potential prognostic marker in gliomasWenjianlong Zhou, Xiangxiang Liu, Jan Willem van Wijnbergen, Linhao Yuan, Yuan Liu, Chuanbao Zhang, Wang Jia · 2020 · Scientific Reports
- Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodelingSaranyaraajan Varadarajan, Shahana A. Chumki, Rachel E. Stephenson, Eileen Misterovich, Jessica Wu, Claire E. Dudley, Ivan S. Erofeev, Andrew Boris Goryachev, Ann Louise Miller · 2022 · The Journal of Cell Biology
- Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettesInes Lüchtefeld, Igor V. Pivkin, Lucia Gardini, Elaheh Zare‐Eelanjegh, Christoph G. Gäbelein, Stephan J. Ihle, Andreas Michael Reichmuth, Marco Capitanio, Boris Martinac, Tomaso Zambelli et al. · 2024 · Nature Methods
- Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cellsDeekshitha Jetta, Philip A. Gottlieb, Deepika Verma, Frederick Sachs, Susan Z. Hua · 2019 · Journal of Cell Science
- Mechanosensitive Piezo1 protein as a novel regulator in macrophages and macrophage-mediated inflammatory diseasesTang, Yu, Zhao, Chuanxiang, Zhuang, Ying, Zhong, Anjing, Wang, Ming, Zhang, Wei, Zhu, Liqun · 2023 · Frontiers in Immunology
- In Touch With the Mechanosensitive Piezo ChannelsJie Geng, Qiuye Zhao, Tingxin Zhang, Bailong Xiao · 2017 · Current topics in membranes
- Calcium Channels and Calcium-Regulated Channels in Human Red Blood CellsLars Kaestner, Anna Y. Bogdanova, Stéphane Égée · 2019 · Advances in experimental medicine and biology
- Adenosine Triphosphate Release and P2 Receptor Signaling in Piezo1 Channel-Dependent MechanoregulationLinyu Wei, Fatema Mousawi, Dongliang Li, Sébastien Roger, Jing Li, Xuebin Yang, Lin‐Hua Jiang · 2019 · Frontiers in Pharmacology
- Identification and Analysis of Putative Homologues of Mechanosensitive Channels in Pathogenic ProtozoaDavid L. Prole, Colin W. Taylor · 2013 · PLoS ONE
- The Piezo1 cation channel mediates uterine artery shear stress mechanotransduction and vasodilation during rat pregnancyLiam John, Nga Ling Ko, A. P. Gokin, Natalia I. Gokina, Maurizio Mandalà, George Osol · 2018 · American Journal of Physiology-Heart and Circulatory Physiology
- PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in miceLiran Xu, Ting Li, Yapeng Cao, Yu He, Zehua Shao, Siyu Liu, Bianbian Wang, Ailing Su, Huijing Tian, Yongxin Li et al. · 2025 · Journal of Clinical Investigation
- Adaptation Independent Modulation of Auditory Hair Cell Mechanotransduction Channel Open Probability Implicates a Role for the Lipid BilayerAnthony W. Peng, Radhakrishnan Gnanasambandam, Frederick Sachs, Anthony J. Ricci · 2016 · Journal of Neuroscience
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- Bone Repairment via Mechanosensation of Piezo1 Using Wearable Pulsed Triboelectric NanogeneratorBingjin Wang, Gaocai Li, Qianqian Zhu, Weifang Liu, Wencan Ke, Wenbin Hua, Yiming Zhou, Xianlin Zeng, Xuhui Sun, Zhen Wen et al. · 2022 · Small
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- Piezo channels in the urinary systemXu Li, Junwei Hu, Xue-Dan Zhao, Juanjuan Li, Yuelai Chen · 2022 · Experimental & Molecular Medicine
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- Functional expression of the mechanosensitive PIEZO1 channel in primary endometrial epithelial cells and endometrial organoidsAurélie Hennes, Katharina Held, Matteo Boretto, Katrien De Clercq, Charlotte Van den Eynde, Arne Vanhie, Nele Van Ranst, Melissa Benoit, C. Luyten, Karen Peeraer et al. · 2019 · Scientific Reports
- How Mechanical Forces Change the Human Endometrium during the Menstrual Cycle in Preparation for Embryo ImplantationAnna K. Sternberg, Volker Uwe Buck, Irmgard Classen-Linke, Rudolf E. Leube · 2021 · Cells
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- Trends in Piezo Channel Research Over the Past Decade: A Bibliometric AnalysisJing Guo, Dongmei Gu, Tingting Zhao, Zhanhao Zhao, Yajun Xiong, Mengzhu Sun, Xin Chen, Yujie Zhang, Lixia Pei, Jianhua Sun · 2021 · Frontiers in Pharmacology
- Mechanical Properties in the Glioma Microenvironment: Emerging Insights and Theranostic OpportunitiesAdip Guruprasad Bhargav, Joseph S. Domino, Roukoz B. Chamoun, Sufi Mary Thomas · 2022 · Frontiers in Oncology
- Matrix stiffness induces epithelial-to-mesenchymal transition via Piezo1-regulated calcium flux in prostate cancer cellsMaria Lopez‐Cavestany, Su Bin Hahn, Jacob M. Hope, Noah T. Reckhorn, Joshua D. Greenlee, Samantha C. Schwager, Jacob A. VanderBurgh, Cynthia A. Reinhart‐King, Michael R. King · 2023 · iScience
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- Piezo1 mediates neuron oxygen-glucose deprivation/reoxygenation injury via Ca2+/calpain signalingYingying Wang, Hao Zhang, Tao Ma, Yan Lu, Hou-Yun Xie, Wei Wang, Yuheng Ma, Guan‐Hua Li, Yong-Wang Li · 2019 · Biochemical and Biophysical Research Communications
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- Hereditary xerocytosis revisitedNatasha M. Archer, Boris E. Shmukler, Immacolata Andolfo, David H. Vandorpe, Radhakrishnan Gnanasambandam, John M. Higgins, Alicia Rivera, Mark D. Fleming, Frederick Sachs, Philip A. Gottlieb et al. · 2014 · American Journal of Hematology
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- The Piezo Mechanosensitive Ion Channels: May the Force Be with You!Éric Honoré, Joana Raquel Martins, David Pentón, Amanda Jane Patel, Sophie Demolombe · 2015 · Reviews of physiology, biochemistry and pharmacology
- Two-Pore-Domain Potassium (K2P-) Channels: Cardiac Expression Patterns and Disease-Specific Remodelling ProcessesFelix Wiedmann, Norbert Frey, Constanze Schmidt · 2021 · Cells
- Activation of Mechanosensitive Transient Receptor Potential/Piezo Channels in Odontoblasts Generates Action Potentials in Cocultured Isolectin B 4 –negative Medium-sized Trigeminal Ganglion NeuronsMasaki Sato, Kazuhiro Ogura, Maki Kimura, Koichi Nishi, Masayuki Ando, Masakazu Tazaki, Yoshiyuki Shibukawa · 2018 · Journal of Endodontics
- Mechanotransduction in gastrointestinal smooth muscle cells: role of mechanosensitive ion channelsVikram Joshi, Peter R. Strege, Gianrico Farrugia, Arthur Beyder · 2021 · American Journal of Physiology-Gastrointestinal and Liver Physiology
- ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brainJormay Lim, Hsiao-Hsin Tai, Wei‐Hao Liao, Ya-Cherng Chu, Chen‐Ming Hao, Yueh-Chun Huang, Cheng‐Han Lee, Shao-Shien Lin, Sherry Hsu, Ya‐Chih Chien et al. · 2021 · eLife
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- The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct β Sandwich FoldAron Kamajaya, Jens T. Kaiser, Jonas Lee, Michelle Reid, Douglas C. Rees · 2014 · Structure
- Mechanosensitive membrane domains regulate calcium entry in arterial endothelial cells to protect against inflammationSoon‐Gook Hong, Julianne W. Ashby, John Paul Kennelly, Meigan Wu, Michelle E. Steel, Eesha Chattopadhyay, Rob Foreman, Peter Tontonoz, Elizabeth J. Tarling, Patric Turowski et al. · 2024 · Journal of Clinical Investigation
- Yoda1-induced phosphorylation of Akt and ERK1/2 does not require Piezo1 activationNathaniel G. dela Paz, John A. Frangos · 2018 · Biochemical and Biophysical Research Communications
- The role of Piezo1 in conventional aqueous humor outflow dynamicsWei Zhu, Fei Hou, Jingwang Fang, Mohammad Reza Bahrani Fard, Yani Liu, Shouyan Ren, Shen Wu, Yun‐Kun Qi, Shangru Sui, A. Thomas Read et al. · 2021 · iScience
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