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Rhamnolipid Surfactants: An Update on the General Aspects of These Remarkable Biomolecules
Abstract
Pseudomonas strains are able to biosynthesize rhamnose‐containing surfactants also known as rhamnolipids. These surface‐active compounds are reviewed with respect to chemical structure, properties, biosynthesis, and physiological role, focusing on their production and the use of low‐cost substrates such as wastes from food industries as alternative carbon sources. The use of inexpensive raw materials such as agroindustrial wastes is an attractive strategy to reduce the production costs associated with biosurfactant production and, at same time, contribute to the reduction of environmental impact generated by the discard of residues, and the treatment costs. Carbohydrate‐rich substrates generated low rhamnolipid levels, whereas oils and lipid‐rich wastes have shown excellent potential as alternative carbon sources.
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Citations
Cites
Microbial production of surfactants and their commercial potential.
Desai, J. D., & Banat, I. M. (1997) · Microbiology and molecular biology reviews : MMBR · doi:10.1128/.61.1.47-64.1997 · Cited by 2,460
Potential commercial applications of microbial surfactants
Banat, I. M., Makkar, R. S., & Cameotra, S. S. (2000) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051648 · Cited by 1,580
Environmental applications for biosurfactants
Mulligan, C. N. (2005) · Environmental Pollution · doi:10.1016/j.envpol.2004.06.009 · Cited by 1,537
Pearson, J. P., Pesci, E. C., & Iglewski, B. H. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.18.5756-5767.1997 · Cited by 1,028
Natural roles of biosurfactants: Minireview
Ron, E. Z., & Rosenberg, E. (2001) · Environmental Microbiology · doi:10.1046/j.1462-2920.2001.00190.x · Cited by 801
Advances in biochemical engineering/biotechnology
(1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90123-9 · Cited by 601
Pseudomonas aeruginosa rhamnolipids: biosynthesis and potential applications
Maier, R. M., & Soberón-Chávez, G. (2000) · Applied Microbiology and Biotechnology · doi:10.1007/s002530000443 · Cited by 593
Cameotra, R. M. (2002) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-001-0924-1 · Cited by 488
Rhamnose lipids - biosynthesis, microbial production and application potential
Lang, S., & Wullbrandt, D. (1999) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051358 · Cited by 469
Abalos, A., Pinazo, A., Infante, M. R., Casals, M., García, F., & Manresa, A. (2001) · Langmuir · doi:10.1021/la0011735 · Cited by 451
Al-Tahhan, R. A., Sandrin, T. R., Bodour, A. A., & Maier, R. M. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.8.3262-3268.2000 · Cited by 436
A Glyco-lipide Produced by Pseudomonas Aeruginosa
Jarvis, F. G., & Johnson, M. J. (1949) · Journal of the American Chemical Society · doi:10.1021/ja01180a073 · Cited by 418
Zhang, Y., & Miller, R. M. (1994) · Applied and Environmental Microbiology · doi:10.1128/aem.60.6.2101-2106.1994 · Cited by 388
Pseudomonas aeruginosa biosurfactant production in continuous culture with glucose as carbon source
Guerra-Santos, L., Käppeli, O., & Fiechter, A. (1984) · Applied and Environmental Microbiology · doi:10.1128/aem.48.2.301-305.1984 · Cited by 387
Benincasa, M., Abalos, A., Oliveira, I., & Manresa, A. (2004) · Antonie van Leeuwenhoek · doi:10.1023/b:anto.0000020148.45523.41 · Cited by 384
Synthesis of biosurfactants in extreme conditions
Cameotra, S. S., & Makkar, R. S. (1998) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051329 · Cited by 342
Haba, E., Espuny, M. J., Busquets, M., & Manresa, A. (2000) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2000.00961.x · Cited by 331
Biosurfactants: moving towards industrial application
Fiechter, A. (1992) · Trends in Biotechnology · doi:10.1016/0167-7799(92)90215-h · Cited by 325
Stanghellini, M. E., & Miller, R. M. (1997) · Plant Disease · doi:10.1094/pdis.1997.81.1.4 · Cited by 319
Rahman, K. S. M., Rahman, T. J., McClean, S., Marchant, R., & Banat, I. M. (2002) · Biotechnology Progress · doi:10.1021/bp020071x · Cited by 304
Déziel, E., Lépine, F., Dennie, D., Boismenu, D., Mamer, O. A., & Villemur, R. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00129-8 · Cited by 292
Effect of the carbon source on biosurfactant production byPseudomonas aeruginosa 44T1
Robert, M., Mercad�, M. E., Bosch, M. P., Parra, J. L., Espuny, M. J., Manresa, M. A., & Guinea, J. (1989) · Biotechnology Letters · doi:10.1007/bf01026843 · Cited by 286
Guerra-Santos, L., K�ppeli, O., & Fiechter, A. (1986) · Applied Microbiology and Biotechnology · doi:10.1007/bf00250320 · Cited by 252
Rhamnolipid production by Pseudomonas aeruginosa LBI growing on soapstock as the sole carbon source
Benincasa, M., Contiero, J., Manresa, M. A., & Moraes, I. O. (2002) · Journal of Food Engineering · doi:10.1016/s0260-8774(01)00214-x · Cited by 246
Self-citationBiosurfactants and biotechnology
Venkata Srinivasa Chari, M. (1988) · Trends in biotechnology · doi:10.1016/0167-7799(88)90069-8 · Cited by 226
Syldatk, C., Lang, S., Wagner, F., Wray, V., & Witte, L. (1985) · Zeitschrift für Naturforschung C · doi:10.1515/znc-1985-1-212 · Cited by 223
Beal, R. E., & Betts, W. B. (2000) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2000.01104.x · Cited by 208
Déziel, E., Lépine, F., Milot, S., & Villemur, R. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00039-1 · Cited by 206
Itoh, S., HONDA, H., Tomita, F., & Suzuki, T. (1971) · The Journal of Antibiotics · doi:10.7164/antibiotics.24.855 · Cited by 202
Mata-Sandoval, J. C., Karns, J., & Torrents, A. (1999) · Journal of Chromatography A · doi:10.1016/s0021-9673(99)00979-6 · Cited by 200
Production and characterisation of a biosurfactant isolated from Pseudomonas aeruginosa UW-1
Sim, L., Ward, O. P., & Li, Z.-Y. (1997) · Journal of Industrial Microbiology and Biotechnology · doi:10.1038/sj.jim.2900450 · Cited by 197
Algicidal activity of rhamnolipid biosurfactants produced by Pseudomonas aeruginosa
Wang, X., Gong, L., Liang, S., Han, X., Zhu, C., & Li, Y. (2005) · Harmful Algae · doi:10.1016/j.hal.2004.06.001 · Cited by 187
From renewable vegetables resources to microorganisms: new trends in surfactants
Deleu, M., & Paquot, M. (2004) · Comptes Rendus. Chimie · doi:10.1016/j.crci.2004.04.002 · Cited by 182
Production of surfactant from Bacillus subtilis ATCC 21332 using potato substrates
Fox, S. L., & Bala, G. A. (2000) · Bioresource Technology · doi:10.1016/s0960-8524(00)00059-6 · Cited by 168
Olive oil mill effluent (OOME). New substrate for biosurfactant production
Mercadé, M. E., Manresa, M. A., Robert, M., Espuny, M. J., de Andrés, C., & Guinea, J. (1993) · Bioresource Technology · doi:10.1016/0960-8524(93)90074-l · Cited by 161
Distillery and curd whey wastes as viable alternative sources for biosurfactant production
Dubey, K., & Juwarkar, A. (2001) · World Journal of Microbiology and Biotechnology · doi:10.1023/a:1016606509385 · Cited by 160
Biosurfactant production by Pseudomonas aeruginosa GS3 from molasses
Patel, R. M., & Desai, A. J. (1997) · Letters in Applied Microbiology · doi:10.1046/j.1472-765x.1997.00172.x · Cited by 158
Production of Pseudomonas aeruginosa Rhamnolipid Biosurfactants in Heterologous Hosts
Ochsner, U. A., Reiser, J., Fiechter, A., & Witholt, B. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.9.3503-3506.1995 · Cited by 157
Syldatk, C., Lang, S., Matulovic, U., & Wagner, F. (1985) · Zeitschrift für Naturforschung C · doi:10.1515/znc-1985-1-213 · Cited by 156
Makkar, R. S., & Cameotra, S. S. (1997) · Journal of the American Oil Chemists Society · doi:10.1007/s11746-997-0233-7 · Cited by 148
The Enzymatic Synthesis of a Rhamnose-containing Glycolipid by Extracts of Pseudomonas aeruginosa
Burger, M. M., Glaser, L., & Burton, R. M. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67872-x · Cited by 147
Chayabutra, C., Wu, J., & Ju, L. (2000) · Biotechnology and Bioengineering · Cited by 144
Correlation of nitrogen metabolism with biosurfactant production by Pseudomonas aeruginosa
Mulligan, C. N., & Gibbs, B. F. (1989) · Applied and Environmental Microbiology · doi:10.1128/aem.55.11.3016-3019.1989 · Cited by 137
Production of biosurfactants from Pseudomonas aeruginosa PA 1 isolated in oil environments
Anna, L. M. M. S., Sebastián, G. V., Menezes, E. P., Alves, T. L. M., dos Santos, A. S., Pereira, N., & Freire, D. M. G. (2002) · Brazilian Journal of Chemical Engineering · doi:10.1590/s0104-66322002000200011 · Cited by 133
Chemical characterization and physicochemical behavior of biosurfactants
Parra, J. L., Guinea, J., Manresa, Á., Robert, M., Mercadé, E., Comelles, F., & Bosch, M. P. (1989) · Journal of the American Oil Chemists Society · doi:10.1007/bf02661805 · Cited by 125
Trummler, K., Effenberger, F., & Syldatk, C. (2003) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.200300816 · Cited by 123
Biosurfactant Production by Bacillus subtilis Using Cassava-Processing Effluent
Nitschke, M., & Pastore, G. M. (2004) · Applied Biochemistry and Biotechnology · doi:10.1385/abab:112:3:163 · Cited by 114
Self-citationMata-Sandoval, J. C., Karns, J. S., & Torrents, A. (2001) · Microbiological Research · doi:10.1016/s0944-5013(01)80001-x · Cited by 111
Haba, E., Ábalos, A., Jáuregui, O., Espuny, M. J., & Manresa, Á. (2003) · Journal of Surfactants and Detergents · doi:10.1007/s11743-003-0260-7 · Cited by 100
Characterisation of Pseudomonas rhamnolipids
Rendell, N. B., Taylor, G. W., Somerville, M. M., Todd, H., Wilson, R. C., & COLE, P. J. (1990) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(90)90150-v · Cited by 96
Ramana, K. V., & Karanth, N. G. (1989) · Journal of Chemical Technology & Biotechnology · doi:10.1002/jctb.280450402 · Cited by 95
Kinetics of biosurfactant production by Pseudomonas aeruginosa strain BS2 from industrial wastes
Babu, P. S., Vaidya, A. N., Bal, A. S., Kapur, R., Juwarkar, A. A., & Khanna, P. (1996) · Biotechnology Letters · doi:10.1007/bf00142942 · Cited by 93
The use of agroindustrial by‐products for biosurfactant production
Mercadé, E., & Manresa, Á. (1994) · Journal of the American Oil Chemists Society · doi:10.1007/bf02541473 · Cited by 93
Genetically-manipulated microorganisms and their products in the oil service industries
Chakrabarty, A. M. (1985) · Trends in biotechnology · doi:10.1016/0167-7799(85)90056-3 · Cited by 76
Improved Production of Rhamnolipids by a Pseudomonas aeruginosa Mutant
Tahzibi, A., Kamal, F., & Assadi, M. M. (2004) · Cited by 73
Rhamnolipid biosurfactant enhancement of hexadecane biodegradation by Pseudomonas aeruginosa.
Shreve, G. S., Inguva, S., & Gunnam, S. (1995) · PubMed · Cited by 72
Reddy, P. G., Singh, H. D., Pathak, M. G., Bhagat, S. D., & Baruah, J. N. (1983) · Biotechnology and Bioengineering · doi:10.1002/bit.260250208 · Cited by 70
Koch, A., Reiser, J., Käppeli, O., & Fiechter, A. (1988) · Nature Biotechnology · doi:10.1038/nbt1188-1335 · Cited by 66
The Potential of Bacterial Isolates for Emulsification with a Range of Hydrocarbons
Rahman, P. K. S. M., Rahman, T., Lakshmanaperumalsamy, P., Marchant, R., & Banat, I. M. (2003) · Acta Biotechnologica · doi:10.1002/abio.200390043 · Cited by 61
Cassava Flour Wastewater as a Substrate for Biosurfactant Production
Nitschke, M., & Pastore, G. M. (2003) · Applied Biochemistry and Biotechnology · doi:10.1385/abab:106:1-3:295 · Cited by 61
Self-citationStudies on the Biosynthesis of l-Rhamnose
Hauser, G., & Karnovsky, M. L. (1958) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64751-9 · Cited by 49
Production of biosurfactants by the resting cells ofPseudomonas aeruginosa CFTR-6
Ramana, K. V., & Karanth, N. G. (1989) · Biotechnology Letters · doi:10.1007/bf01089479 · Cited by 26
The production of interfacial emulsions by bacterial isolates from diesel fuels
Bento, F. M., & Gaylarde, C. C. (1996) · International Biodeterioration & Biodegradation · doi:10.1016/s0964-8305(96)00021-2 · Cited by 20
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Biosurfactants in food industry
Nitschke, M., & Costa, S. G. V. A. O. (2007) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2007.01.002 · Cited by 581
Self-citationAdvances in utilization of renewable substrates for biosurfactant production
Makkar, R. S., Cameotra, S. S., & Banat, I. M. (2011) · AMB Express · doi:10.1186/2191-0855-1-5 · Cited by 470
Biosurfactants production by yeasts using soybean oil and glycerol as low cost substrate
Accorsini, F. R., Mutton, M. J. R., Lemos, E. G. M., & Benincasa, M. (2012) · Brazilian Journal of Microbiology · doi:10.1590/s1517-83822012000100013 · Cited by 62
Enhanced aqueous solubilization of tetrachloroethylene by a rhamnolipid biosurfactant
Clifford, J. S., Ioannidis, M. A., & Legge, R. L. (2007) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2006.10.026 · Cited by 46
Degradation of Macondo 252 oil by endophytic Pseudomonas putida
Zheng, M., Wang, W., Hayes, M., Nydell, A., Tarr, M. A., Van Bael, S. A., & Papadopoulos, K. (2018) · Journal of Environmental Chemical Engineering · doi:10.1016/j.jece.2017.12.071 · Cited by 40
Metadata
- Authors
- Nitschke, M., Costa, S. G. V. A. O., & Contiero, J.
- Venue
- Biotechnology Progress
- Publisher
- Wiley
- Published
- 2005-01
- Volume
- 21
- Issue
- 6
- Pages
- 1593-1600
- ISSN
- 1520-6033 (ISSN-L)
- 8756-7938
- OpenAlex
- W2059607527
- Cited by
- 300
- References
- 63
- FWCI
- 11.94
- Type
- journal article
- Language
- en
- Open access
- closed
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