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Development of Magnetic Nanostructured Silica-Based Materials as Potential Vectors for Drug-Delivery Applications
Abstract
Metallic iron nanoparticles were synthesized within micron-sized mesoporous molecular sieves (with 2.9-nm pores) and hollow silica microcapsules (pores of 2.7 and 15 nm) using several cycles of wet impregnation under vacuum, followed by drying, oxidation, and reduction steps. For iron-loaded MCM-48, SQUID measurements revealed ferromagnetic behavior at room temperature with a magnetic moment as high as 3.40 emu/g (measured at 2 T) after four deposition cycles. Iron-loaded hollow silica microcapsules (250-nm wall thickness) showed a magnetic moment of 2.40 emu/g (at 2 T) after three deposition cycles and a coercivity as low as 12.9 Oe.
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Citations
Cited by
Reddy, L. H., Arias, J. L., Nicolas, J., & Couvreur, P. (2012) · Chemical Reviews · doi:10.1021/cr300068p · Cited by 2,010
Mesoporous silica nanoparticles for drug delivery and biosensing applications
Slowing, I. I., Trewyn, B. G., Giri, S., & Lin, V. S. ‐. (2007) · Advanced Functional Materials · doi:10.1002/adfm.200601191 · Cited by 1,699
Light‐Activated Nanoimpeller‐Controlled Drug Release in Cancer Cells
Lu, J., Choi, E., Tamanoi, F., & Zink, J. I. (2008) · Small · doi:10.1002/smll.200700903 · Cited by 462
New developments in ordered mesoporous materials for drug delivery
Manzano, M., & Vallet-Regí, M. (2010) · Journal of Materials Chemistry · doi:10.1039/b922651f · Cited by 359
Cao, S.-W., Zhu, Y.-J., Ma, M.-Y., Li, L., & Zhang, L. (2008) · The Journal of Physical Chemistry C · doi:10.1021/jp077468+ · Cited by 342
Metadata
- Authors
- Arruebo, M., Galán, M., Navascués, N., Téllez, C., Marquina, C., Ibarra, M. R., & Santamaría, J.
- Venue
- Chemistry of Materials
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-03-14
- Volume
- 18
- Issue
- 7
- Pages
- 1911-1919
- ISSN
- 0897-4756 (ISSN-L)
- 1520-5002
- OpenAlex
- W2058478190
- Cited by
- 231
- References
- 0
- FWCI
- 15.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- Arruebo, M., Galán, M., Navascués, N., Téllez, C., Marquina, C., Ibarra, M. R., & Santamaría, J. (2006). Development of Magnetic Nanostructured Silica-Based Materials as Potential Vectors for Drug-Delivery Applications. Chemistry of Materials. https://doi.org/10.1021/cm051646z
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