New developments in ordered mesoporous materials for drug delivery

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Triblock Copolymer Syntheses of Mesoporous Silica with Periodic 50 to 300 Angstrom Pores

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How useful is SBF in predicting in vivo bone bioactivity?

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Nonionic Triblock and Star Diblock Copolymer and Oligomeric Surfactant Syntheses of Highly Ordered, Hydrothermally Stable, Mesoporous Silica Structures

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Silica‐Based Mesoporous Organic–Inorganic Hybrid Materials

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Third-Generation Biomedical Materials

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On the mechanisms of biocompatibility

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Mesoporous Materials for Drug Delivery

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Synthesis of Highly Ordered Carbon Molecular Sieves via Template-Mediated Structural Transformation

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A New Property of MCM-41: Drug Delivery System

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The Preparation of Alkyltrimethylammonium–Kanemite Complexes and Their Conversion to Microporous Materials

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New Methods of Drug Delivery

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A Mesoporous Silica Nanosphere-Based Carrier System with Chemically Removable CdS Nanoparticle Caps for Stimuli-Responsive Controlled Release of Neurotransmitters and Drug Molecules

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Cooperative Formation of Inorganic-Organic Interfaces in the Synthesis of Silicate Mesostructures

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Synthesis of highly ordered mesoporous materials from a layered polysilicate

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Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica

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Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs

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Stimuli‐Responsive Controlled Drug Release from a Hollow Mesoporous Silica Sphere/Polyelectrolyte Multilayer Core–Shell Structure

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Stimuli‐Responsive Controlled‐Release Delivery System Based on Mesoporous Silica Nanorods Capped with Magnetic Nanoparticles

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Surface-Active Biomaterials

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Ceramic-Based Nanoparticles Entrapping Water-Insoluble Photosensitizing Anticancer Drugs: A Novel Drug−Carrier System for Photodynamic Therapy

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A Polyamidoamine Dendrimer-Capped Mesoporous Silica Nanosphere-Based Gene Transfection Reagent

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Mesocellular Siliceous Foams with Uniformly Sized Cells and Windows

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Functionalized SBA-15 Materials as Carriers for Controlled Drug Delivery: Influence of Surface Properties on Matrix−Drug Interactions

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MCM-41 Organic Modification as Drug Delivery Rate Regulator

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The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells

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Influence of pore size of MCM-41 matrices on drug delivery rate

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A novel anionic surfactant templating route for synthesizing mesoporous silica with unique structure

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The biocompatibility of mesoporous silicates

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Ceramics for medical applications

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Inclusion of ibuprofen in mesoporous templated silica: drug loading and release property

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Ordered Mesoporous Materials in the Context of Drug Delivery Systems and Bone Tissue Engineering

Vallet‐Regí, M. (2006) · Chemistry - A European Journal · doi:10.1002/chem.200600226 · Cited by 517 · see citing works

Light-Operated Mechanized Nanoparticles

Ferris, D. P., Zhao, Y., Khashab, N. M., Khatib, H. A., Stoddart, J. F., & Zink, J. I. (2009) · Journal of the American Chemical Society · doi:10.1021/ja807798g · Cited by 507 · see citing works

pH-Responsive Carrier System Based on Carboxylic Acid Modified Mesoporous Silica and Polyelectrolyte for Drug Delivery

Qing, Y., Wang, S., Fan, P., Wang, L., Di, Y., Lin, K., & Xiao, F. (2005) · Chemistry of Materials · doi:10.1021/cm051198v · Cited by 490 · see citing works

A reversible molecular valve

Nguyen, T. D., Tseng, H., Celestre, P. C., Flood, A. H., Liu, Y., Stoddart, J. F., & Zink, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504109102 · Cited by 464 · see citing works

Light‐Activated Nanoimpeller‐Controlled Drug Release in Cancer Cells

Lu, J., Choi, E., Tamanoi, F., & Zink, J. I. (2008) · Small · doi:10.1002/smll.200700903 · Cited by 462 · see citing works

Controlled Release of Guest Molecules from Mesoporous Silica Particles Based on a pH‐Responsive Polypseudorotaxane Motif

Park, C., Oh, K., Lee, S. C., & Kim, C. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200603404 · Cited by 453 · see citing works

An Operational Supramolecular Nanovalve

Hernández, R. T., Tseng, H., Wong, J. W. H., Stoddart, J. F., & Zink, J. I. (2004) · Journal of the American Chemical Society · doi:10.1021/ja039424u · Cited by 439 · see citing works

Confinement and Controlled Release of Bisphosphonates on Ordered Mesoporous Silica-Based Materials

Balas, F., Manzano, M., Horcajada, P., & Vallet‐Regí, M. (2006) · Journal of the American Chemical Society · doi:10.1021/ja062286z · Cited by 437 · see citing works

Well-Ordered Mesoporous Silica Nanoparticles as Cell Markers

Lin, Y., Tsai, C., Huang, H.-Y., Kuo, C., Hung, Y., Huang, D., Chen, Y., & Mou, C. (2005) · Chemistry of Materials · doi:10.1021/cm051014c · Cited by 424 · see citing works

Glasses with Medical Applications

Vallet‐Regí, M., Ragel, C. V., & Salinas, A. J. (2003) · European Journal of Inorganic Chemistry · doi:10.1002/ejic.200390134 · Cited by 423 · see citing works

Design and Optimization of Molecular Nanovalves Based on Redox-Switchable Bistable Rotaxanes

Nguyen, T. D., Liu, Y., Saha, S., Leung, K. C., Stoddart, J. F., & Zink, J. I. (2007) · Journal of the American Chemical Society · doi:10.1021/ja065485r · Cited by 397 · see citing works

Mesoporous SBA-15 HPLC evaluation for controlled gentamicin drug delivery

Doadrio, A. L., de Sousa, E. M. B., Doadrio, A. L., Pérez‐Pariente, J., Izquierdo‐Barba, I., & Vallet‐Regí, M. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.03.005 · Cited by 374 · see citing works

Functionalization of mesoporous materials with long alkyl chains as a strategy for controlling drug delivery pattern

Doadrio, J. C., de Sousa, E. M. B., Izquierdo‐Barba, I., Doadrio, A. L., Pérez‐Pariente, J., & Vallet‐Regí, M. (2005) · Journal of Materials Chemistry · doi:10.1039/b510101h · Cited by 328 · see citing works

Revisiting silica based ordered mesoporous materials: medical applications

Vallet‐Regí, M., Ruiz‐González, L., Izquierdo‐Barba, I., & González-Calbet, J. M. (2005) · Journal of Materials Chemistry · doi:10.1039/b509744d · Cited by 326 · see citing works

Controlled release of Captopril by regulating the pore size and morphology of ordered mesoporous silica

Qu, F., Zhu, G., Huang, S., Li, S., Sun, J., Zhang, D., & Qiu, S. (2006) · Microporous and Mesoporous Materials · doi:10.1016/j.micromeso.2005.12.004 · Cited by 297 · see citing works

Control of Molecular Transport Through Stimuli‐Responsive Ordered Mesoporous Materials

Fu, Q., Rao, G. V. R., Ista, L. K., Wu, Y., Andrzejewski, B. P., Sklar, L. A., Ward, T. L., & López, G. P. (2003) · Advanced Materials · doi:10.1002/adma.200305165 · Cited by 282 · see citing works

Biocompatible mesoporous silica nanoparticles with different morphologies for animal cell membrane penetration

Trewyn, B. G., Nieweg, J. A., Zhao, Y., & Lin, V. S. ‐. (2007) · Chemical Engineering Journal · doi:10.1016/j.cej.2007.09.045 · Cited by 275 · see citing works

Revisiting ceramics for medical applications

Vallet-Reg, M. A. (2006) · Dalton Transactions · doi:10.1039/b610219k · Cited by 263 · see citing works

Construction of a pH-Driven Supramolecular Nanovalve

Nguyen, T. D., Leung, K. C., Liong, M., Pentecost, C. D., Stoddart, J. F., & Zink, J. I. (2006) · Organic Letters · doi:10.1021/ol0612509 · Cited by 249 · see citing works

Ultrasound‐Triggered Smart Drug Release from a Poly(dimethylsiloxane)– Mesoporous Silica Composite

Kim, H. ‐., Matsuda, H., Zhou, H., & Honma, I. (2006) · Advanced Materials · doi:10.1002/adma.200600387 · Cited by 239 · see citing works

Selective Functionalization of the Outer and Inner Surfaces in Mesoporous Silica Nanoparticles

Kecht, J., Schloßbauer, A., & Bein, T. (2008) · Chemistry of Materials · doi:10.1021/cm801484r · Cited by 238 · see citing works

Mesoporous silica material TUD-1 as a drug delivery system

Heikkilä, T., Salonen, J., Tuura, J., Hamdy, M. S., Mul, G., Kumar, N., Salmi, T., Murzin, D. Y., LAITINEN, L., & Kaukonen, A. M. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.09.019 · Cited by 236 · see citing works

Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials

Mellaerts, R., Aerts, C. A., Humbeeck, J. V., Augustijns, P., den Mooter, G. V., & Martens, J. A. (2007) · Chemical Communications · doi:10.1039/b616746b · Cited by 233 · see citing works

Development of Magnetic Nanostructured Silica-Based Materials as Potential Vectors for Drug-Delivery Applications

Arruebo, M., Galán, M., Navascués, N., Téllez, C., Marquina, C., Ibarra, M. R., & Santamarı́a, J. (2006) · Chemistry of Materials · doi:10.1021/cm051646z · Cited by 231 · see citing works

Cytotoxicity of mesoporous silica nanomaterials

Pasqua, A. J. D., Sharma, K. K., Shi, Y.-L., Toms, B. B., Ouellette, W., Dabrowiak, J. C., & Asefa, T. (2008) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2007.12.028 · Cited by 227 · see citing works

Size selective protein adsorption on thiol-functionalised SBA-15 mesoporous molecular sieve

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Release evaluation of drugs from ordered three-dimensional silica structures

Izquierdo‐Barba, I., Martinez, Á., Doadrio, A. L., Pérez‐Pariente, J., & Vallet‐Regí, M. (2005) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2005.06.009 · Cited by 221 · see citing works

Tissue regeneration: A new property of mesoporous materials

Izquierdo‐Barba, I., Ruiz‐González, L., Doadrio, J. C., González-Calbet, J. M., & Vallet‐Regí, M. (2005) · Solid State Sciences · doi:10.1016/j.solidstatesciences.2005.04.003 · Cited by 211 · see citing works

Multifunctional Mesoporous Silica Nanoparticles for Intracellular Labeling and Animal Magnetic Resonance Imaging Studies

Wu, S., Lin, Y., Hung, Y., Chou, Y., Hsu, Y., Chen, C., & Mou, C. (2007) · ChemBioChem · doi:10.1002/cbic.200700509 · Cited by 209 · see citing works

Grafting of thermo-responsive polymer inside mesoporous silica with large pore size using ATRP and investigation of its use in drug release

Zhou, Z., Zhu, S., & Zhang, D. (2007) · Journal of Materials Chemistry · doi:10.1039/b618834f · Cited by 204 · see citing works

Hexagonal ordered mesoporous material as a matrix for the controlled release of amoxicillin

Vallet‐Regí, M. (2004) · Solid State Ionics · doi:10.1016/j.ssi.2004.04.036 · Cited by 196 · see citing works

Supramolecular Nanovalves Controlled by Proton Abstraction and Competitive Binding

Leung, K. C., Nguyen, T. D., Stoddart, J. F., & Zink, J. I. (2006) · Chemistry of Materials · doi:10.1021/cm061682d · Cited by 194 · see citing works

The chemistry of silica and its potential health benefits.

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Nanostructured mesoporous silica matrices in nanomedicine

Vallet-Regí, M. (2010) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02190.x · Cited by 174 · see citing works

Site-Directed Surface Derivatization of MCM-41: Use of High-Resolution Transmission Electron Microscopy and Molecular Recognition for Determining the Position of Functionality within Mesoporous Materials

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Aerosol-Assisted Synthesis of Magnetic Mesoporous Silica Spheres for Drug Targeting

Ruiz‐Hernández, E., López‐Noriega, A., Arcos, D., Izquierdo‐Barba, I., Terasaki, O., & Vallet‐Regí, M. (2007) · Chemistry of Materials · doi:10.1021/cm0705789 · Cited by 155 · see citing works

PLGA/mesoporous silica hybrid structure for controlled drug release

Xue, J. M., & Shi, M. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.04.023 · Cited by 151 · see citing works

Bone-regenerative bioceramic implants with drug and protein controlled delivery capability

Vallet‐Regí, M., Balas, F., Colilla, M., & Manzano, M. (2007) · Progress in Solid State Chemistry · doi:10.1016/j.progsolidstchem.2007.10.002 · Cited by 149 · see citing works

Influence of superficial organic modification of MCM-41 matrices on drug delivery rate

Horcajada, P., Ramila, A., Férey, G., & Vallet‐Regí, M. (2006) · Solid State Sciences · doi:10.1016/j.solidstatesciences.2006.04.016 · Cited by 146 · see citing works

A study of carboxylic-modified mesoporous silica in controlled delivery for drug famotidine

Tang, Q., Xu, Y., Wu, D. Q., & Sun, Y. (2006) · Journal of Solid State Chemistry · doi:10.1016/j.jssc.2006.02.004 · Cited by 146 · see citing works

Organic modified mesoporous MCM-41 through solvothermal process as drug delivery system

Zeng, W. L., Qian, X., Zhang, Y., Yin, J., & Zhu, Z. (2005) · Materials Research Bulletin · doi:10.1016/j.materresbull.2005.02.011 · Cited by 140 · see citing works

Functionalization degree of SBA-15 as key factor to modulate sodium alendronate dosage

Nieto, A., Balas, F., Colilla, M., Manzano, M., & Vallet‐Regí, M. (2008) · Microporous and Mesoporous Materials · doi:10.1016/j.micromeso.2008.03.025 · Cited by 137 · see citing works

Drug Delivery Devices Based on Mesoporous Silicate

Cavallaro, G., Pierro, P., Palumbo, F. S., Testa, F., Pasqua, L., & Aiello, R. (2004) · Drug Delivery · doi:10.1080/10717540490265252 · Cited by 134 · see citing works

pH-Controllable drug release using hydrogel encapsulated mesoporous silica

Song, S., Hidajat, K., & Kawi, S. (2007) · Chemical Communications · doi:10.1039/b707626f · Cited by 134 · see citing works

Synthesis and Characterization of Mesoporous Silica AMS‐10 with Bicontinuous Cubic Pn$\bar 3$m Symmetry

Gao, C., Sakamoto, Y., Sakamoto, K., Terasaki, O., & Che, S. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200504114 · Cited by 132 · see citing works

Recent advances in ceramic implants as drug delivery systems for biomedical applications

Vallet‐Regí, M., Colilla, M., & Manzano, M. (2008) · International Journal of Nanomedicine · doi:10.2147/ijn.s3548 · Cited by 126 · see citing works

Studies on a new carrier of trimethylsilyl-modified mesoporous material for controlled drug delivery

Tang, Q., Xu, Y., Wu, D. Q., Sun, Y., Wang, J., Xu, J., & Deng, F. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.05.006 · Cited by 122 · see citing works

Comparison of Micro‐ and Mesoporous Inorganic Materials in the Uptake and Release of the Drug Model Fluorescein and Its Analogues

Fisher, K. A., Huddersman, K. D., & Taylor, M. J. (2003) · Chemistry - A European Journal · doi:10.1002/chem.200304764 · Cited by 118 · see citing works

Effective Controlled Release of Captopril by Silylation of Mesoporous MCM‐41

Qu, F., Zhu, G., Huang, S., Li, S., & Qiu, S. (2006) · ChemPhysChem · doi:10.1002/cphc.200500294 · Cited by 116 · see citing works

Controlling and Imaging the Functional‐Group Distribution on Mesoporous Silica

Gartmann, N., & Brühwiler, D. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200902436 · Cited by 111 · see citing works

Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate

Ambrogi, V., Perioli, L., Marmottini, F., Giovagnoli, S., Esposito, M., & Rossi, C. R. (2007) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2007.07.005 · Cited by 108 · see citing works

Loading and delivery of sertraline using inorganic micro and mesoporous materials

Nunes, C. D., Vaz, P. D., Fernandes, A. C., Ferreira, P., Romão, C. C., & Calhorda, M. J. (2006) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2006.11.023 · Cited by 105 · see citing works

Osteostatin-loaded bioceramics stimulate osteoblastic growth and differentiation

Lozano, D., Manzano, M., Doadrio, J. C., Salinas, A. J., Vallet‐Regí, M., Gómez‐Barrena, E., & Esbrit, P. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.08.033 · Cited by 98 · see citing works

The Potential of Ordered Mesoporous Silica for the Storage of Drugs: The Example of a Pentapeptide Encapsulated in a MSU‐Tween 80

Tourné‐Péteilh, C., Lerner, D. A., Charnay, C., Nicole, L., Bégu, S., & Devoisselle, J. (2003) · ChemPhysChem · doi:10.1002/cphc.200390045 · Cited by 94 · see citing works

Three‐Dimensional Ultralarge‐Pore Ia3d Mesoporous Silica with Various Pore Diameters and Their Application in Biomolecule Immobilization

Vinu, A., Gokulakrishnan, N., Balasubramanian, V. V., Alam, S., Kapoor, M. P., Ariga, K., & Mori, T. (2008) · Chemistry - A European Journal · doi:10.1002/chem.200801304 · Cited by 94 · see citing works

Diffusion-Based Deprotection in Mesoporous Materials: A Strategy for Differential Functionalization of Porous Silica Particles

Cheng, K., & Landry, C. C. (2007) · Journal of the American Chemical Society · doi:10.1021/ja070598b · Cited by 93 · see citing works

L-Trp adsorption into silica mesoporous materials to promote bone formation

Balas, F., Manzano, M., Colilla, M., & Vallet‐Regí, M. (2008) · Acta Biomaterialia · doi:10.1016/j.actbio.2007.11.009 · Cited by 86 · see citing works

pH-Controlled drug release from mesoporous silica tablets coated with hydroxypropyl methylcellulose phthalate

Xu, W., Gao, Q., Xu, Y., Wu, D. Q., & Sun, Y. (2008) · Materials Research Bulletin · doi:10.1016/j.materresbull.2008.07.001 · Cited by 81 · see citing works

Ordered Mesoporous Silica Derived from Layered Silicates

Kimura, T., & Kuroda, K. (2009) · Advanced Functional Materials · doi:10.1002/adfm.200800647 · Cited by 72 · see citing works

Unique Uptake of Acid-Prepared Mesoporous Spheres by Lung Epithelial and Mesothelioma Cells

Blumen, S. R., Cheng, K., Ramos‐Niño, M. E., Taatjes, D. J., Weiss, D. J., Landry, C. C., & Mossman, B. T. (2006) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2006-0319oc · Cited by 68 · see citing works

Hierarchical pore structure of calcium phosphate scaffolds by a combination of gel-casting and multiple tape-casting methods

Sánchez‐Salcedo, S., Werner, J., & Vallet‐Regí, M. (2008) · Acta Biomaterialia · doi:10.1016/j.actbio.2008.02.005 · Cited by 67 · see citing works

Silica-based nanoporous sol-gel glasses: from bioencapsulation to protein folding studies

Menaa, B., Menaa, F., Guimarães, C. A., & Sharts, O. N. (2009) · International Journal of Nanotechnology · doi:10.1504/ijnt.2010.029546 · Cited by 66 · see citing works

Nonsurfactant Supramolecular Synthesis of Ordered Mesoporous Silica

Atluri, R., Hedin, N., & Garcia‐Bennett, A. E. (2009) · Journal of the American Chemical Society · doi:10.1021/ja8096477 · Cited by 61 · see citing works

Mesoporous magnetic microspheres for drug targeting

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Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis

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Light‐ and pH‐Responsive Release of Doxorubicin from a Mesoporous Silica‐Based Nanocarrier

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The osteoinductive properties of mesoporous silicate coated with osteostatin in a rabbit femur cavity defect model

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Targeted therapy of kidney disease with nanoparticle drug delivery materials

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One‐pot Synthesis of Ordered Mesoporous NiCeAl Oxide Catalysts and a Study of Their Performance in Methane Dry Reforming

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