The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease

Biochemical Characterization of Various Catalytic Complexes of the Brain Platelet-activating Factor Acetylhydrolase

Manya, H., Aoki, J., Kato, H., Ishii, J., Hino, S., Arai, H., & Inoue, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.45.31827 · Cited by 69

Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach

Shanado, Y., Kometani, M., Uchiyama, H., Koizumi, S., & Teno, N. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.10.193 · Cited by 68

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)

Maes, M., Lambeir, A., Gilany, K., Senten, K., der Veken, P. V., Leiting, B., Augustyns, K., Scharpé, S., & Meester, I. D. (2005) · Biochemical Journal · doi:10.1042/bj20041156 · Cited by 68

Expression of Oncogenic Antigen 519 (OA-519) in Prostate Cancer Is a Potential Prognostic Indicator

Shurbaji, M. S., Kuhajda, F. P., Pasternack, G. R., & Thurmond, T. S. (1992) · American Journal of Clinical Pathology · doi:10.1093/ajcp/97.5.686 · Cited by 67

Role of a serum phospholipase A1in the phosphatidylserine‐induced T cell inhibition

Bellini, F., & Bruni, A. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)81724-e · Cited by 67

Lipoprotein lipase and endothelial lipase expression in mouse brain: regional distribution and selective induction following kainic acid-induced lesion and focal cerebral ischemia

Paradis, É., Clavel, S., Julien, P., Murthy, M. R. V., de Bilbao, F., Arsenijevic, D., Giannakopoulos, P., Vallet, P., & Richard, D. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2003.09.017 · Cited by 67

Bile Salt-stimulated Carboxyl Ester Lipase Influences Lipoprotein Assembly and Secretion in Intestine

Kirby, R. J., Zheng, S., Tso, P., Howles, P. N., & Hui, D. Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107549200 · Cited by 67

Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene.

Ameis, D., Kobayashi, J., Davis, R. C., Ben-Zeev, O., Malloy, M. J., Kane, J. P., Lee, G., Wong, H., Havel, R. J., & Schotz, M. C. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115114 · Cited by 66

Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1

Hirano, T., Kishi, M., Sugimoto, H., Taguchi, R., Obinata, H., Ohshima, N., Tatei, K., & Izumi, T. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.05.001 · Cited by 66

Expression and characterization of recombinant human acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides

Hagen, F. S., Grant, F. J., Kuijper, J. L., Slaughter, C. A., Moomaw, C. R., Orth, K., O’Hara, P. J., & Munford, R. S. (1991) · Biochemistry · doi:10.1021/bi00098a020 · Cited by 66

Molecular cloning and characterization of a mitochondrial peroxisome proliferator-induced acyl-CoA thioesterase from rat liver

Svensson, T., ENGBERG, T. S., Aoyama, T., Usuda, N., ALEXSON, E. H. S., & Hashimoto, T. (1998) · Biochemical Journal · doi:10.1042/bj3290601 · Cited by 66

An Alternative Splicing Form of Phosphatidylserine-specific Phospholipase A1 That Exhibits Lysophosphatidylserine-specific Lysophospholipase Activity in Humans

Nagai, Y., Aoki, J., Sato, T., Amano, K., Matsuda, Y., Arai, H., & Inoue, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.16.11053 · Cited by 65

p125A exists as part of the mammalian Sec13/Sec31 COPII subcomplex to facilitate ER-Golgi transport

Ong, Y. S., Tang, B. L., Loo, L. S., & Hong, W. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201003005 · Cited by 65

Expanding the Dipeptidyl Peptidase 4-Regulated Peptidome via an Optimized Peptidomics Platform

Tinoco, A. D., Tagore, D. M., & Saghatelian, A. (2010) · Journal of the American Chemical Society · doi:10.1021/ja909524e · Cited by 64

Synthesis and Structure−Activity Relationship for a Novel Class of Potent and Selective Carbamoyl-Triazole Based Inhibitors of Hormone Sensitive Lipase

Ebdrup, S., Sørensen, L. G., Olsen, O. H., & Jacobsen, P. (2003) · Journal of Medicinal Chemistry · doi:10.1021/jm031004s · Cited by 64

The Aryl Acylamidases and Their Relationship to Cholinesterases in Human Serum, Erythrocyte and Liver

George, S. T., & Balasubramanian, A. S. (1981) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb06447.x · Cited by 64

Acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides, has phospholipase, lysophospholipase, diacylglycerollipase, and acyltransferase activities in vitro.

Munford, R. S., & Hunter, J. P. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50207-1 · Cited by 63

Peptidase substrates via global peptide profiling

Tagore, D. M., Nolte, W. M., Neveu, J. M., Rangel, R., Guzman‐Rojas, L., Pasqualini, R., Arap, W., Lane, W. S., & Saghatelian, A. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.126 · Cited by 63

Plasma PAF-acetylhydrolase: An unfulfilled promise?

Karabina, S., & Ninio, E. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2006.05.008 · Cited by 63

Molecular mechanism of lysosomal sialidase deficiency in galactosialidosis involves its rapid degradation

VINOGRADOVA, V. M., MICHAUD, L., MEZENTSEV, V. A., LUKONG, E. K., EL-ALFY, M., MORALES, R. C., POTIER, M., & PSHEZHETSKY, V. A. (1998) · Biochemical Journal · doi:10.1042/bj3300641 · Cited by 63

Characterization of the Rodent Genes for Arylacetamide Deacetylase, a Putative Microsomal Lipase, and Evidence for Transcriptional Regulation

Trickett, J. I., Patel, D. D., Knight, B. L., SAGGERSON, E. D., Gibbons, G. F., & Pease, R. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101764200 · Cited by 63

A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability

Woitach, J. T., Zhang, M., Niu, C., & Thorgeirsson, S. S. (1998) · Nature Genetics · doi:10.1038/1258 · Cited by 62

S 17092-1, a Highly Potent, Specific and Cell Permeant Inhibitor of Human Proline Endopeptidase

Barelli, H., Petit-Paitel, A., Hirsch, É. C., Wilk, S., Nanteuil, G. D., Morain, P., & Checler, F. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0366 · Cited by 62

Pancreatic Triglyceride Lipase Deficiency Minimally Affects Dietary Fat Absorption but Dramatically Decreases Dietary Cholesterol Absorption in Mice

Huggins, K. W., Camarota, L. M., Howles, P. N., & Hui, D. Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303422200 · Cited by 62

Altered Striatal Function and Muscarinic Cholinergic Receptors in Acetylcholinesterase Knockout Mice

Volpicelli‐Daley, L. A., Hrabovská, A., Duysen, E. G., Ferguson, S. M., Blakely, R., Lockridge, O., & Levey, A. I. (2003) · Molecular Pharmacology · doi:10.1124/mol.64.6.1309 · Cited by 62

Characterization of Tunable Piperidine and Piperazine Carbamates as Inhibitors of Endocannabinoid Hydrolases

Long, J. Z., Jin, X., Adibekian, A., Li, W., & Cravatt, B. F. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm9016976 · Cited by 62

Human lysosomal protective protein. Glycosylation, intracellular transport, and association with beta-galactosidase in the endoplasmic reticulum.

Morreau, H., Galjart, N., Willemsen, R., Gillemans, N., Zhou, X., & d’Azzo, A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)37135-2 · Cited by 61

Cloning and expression of the murine sws/NTE gene

Moser, M., Stempfl, T., Li, Y., Glynn, P., Büttner, R., & Kretzschmar, D. (2000) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00239-7 · Cited by 61

In vitro SAR of (5-(2H)-isoxazolonyl) ureas, potent inhibitors of hormone-sensitive lipase

Lowe, D., Magnuson, S. R., Qi, N. L., et al. (2004) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2004.04.015 · Cited by 61

Dramatic Accumulation of Triglycerides and Precipitation of Cardiac Hemodynamic Dysfunction during Brief Caloric Restriction in Transgenic Myocardium Expressing Human Calcium-independent Phospholipase A2γ

Mancuso, D. J., Han, X., Jenkins, C. M., Lehman, J. J., Sambandam, N., Sims, H. F., Yang, J., Yan, W., Yang, K., Green, K., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m607307200 · Cited by 60

Effect of S 17092, a novel prolyl endopeptidase inhibitor, on substance P and α‐melanocyte‐stimulating hormone breakdown in the rat brain

Bellemère, G., Morain, P., Vaudry, H., & Jégou, S. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01536.x · Cited by 59

On the question of half- or full-site reactivity of animal fatty acid synthetase.

Singh, N., Wakil, S. J., & Stoops, J. K. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43136-x · Cited by 59

Spatial control of protein phosphatase 2A (de)methylation

Longin, S., Zwaenepoel, K., Martens, E., Louis, J. V., Rondelez, E., Goris, J., & Janssens, V. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.07.030 · Cited by 59

Lysosomal Protective Protein/Cathepsin A

Bonten, E. J., Galjart, N. J., Willemsen, R., Usmany, M., Vlak, J. M., & d'Azzo, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.44.26441 · Cited by 59

Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design.

Pappenberger, G., Benz, J., Gsell, B., Hennig, M., Ruf, A., Stihle, M., Thoma, R., & Rudolph, M. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.01.066 · Cited by 59

Establishment of an Improved Mouse Model for Infantile Neuroaxonal Dystrophy That Shows Early Disease Onset and Bears a Point Mutation in Pla2g6

Wada, H., Yasuda, T., Miura, I., Watabe, K., Sawa, C., Kamijuku, H., Kojo, S., Taniguchi, M., Nishino, I., Wakana, S., et al. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.090343 · Cited by 58

Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease

Dobrovolsky, V. N., Bucci, T. J., Heflich, R. H., Desjardins, J. P., & Richardson, F. C. (2003) · Molecular Genetics and Metabolism · doi:10.1016/s1096-7192(02)00224-x · Cited by 58

Regulation of protein phosphatase 2A methylation by LCMT1 and PME‐1 plays a critical role in differentiation of neuroblastoma cells

Sontag, J., Nunbhakdi‐Craig, V., Mitterhuber, M., Ogris, E., & Sontag, E. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07049.x · Cited by 57

Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2γ-deficient mice

Yoda, E., Hachisu, K., Taketomi, Y., Yoshida, K., Nakamura, M., Ikeda, K., Taguchi, R., Nakatani, Y., Kuwata, H., Murakami, M., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m008060 · Cited by 57

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

Soisson, S. M., Patel, S. B., Abeywickrema, P. D., Bryne, N. J., Diehl, R. E., Hall, D. L., Ford, R. E., Reid, J. C., Rickert, K. W., Shipman, J. M., et al. (2010) · BMC Structural Biology · doi:10.1186/1472-6807-10-16 · Cited by 57

Cholesteryl ester storage disease and Wolman disease: phenotypic variants of lysosomal acid cholesteryl ester hydrolase deficiency.

Jm, H., Demosky, S. J., Pescovitz, O. H., & Brewer, H. B. (1984) · Europe PMC (PubMed Central) · Cited by 56

The Peroxisome Proliferator-induced Cytosolic Type I Acyl-CoA Thioesterase (CTE-I) Is a Serine-Histidine-Aspartic Acid α/β Hydrolase

Huhtinen, K., O'Byrne, J., Lindquist, P. J. G., Contreras, J. A., & Alexson, S. E. H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109040200 · Cited by 56

Esterification of Oxysterols by Human Plasma Lecithin-Cholesterol Acyltransferase

Szedlacsek, S. E., Wa̧sowicz, E., Hulea, S. A., Nishida, H. I., Kummerow, F. A., & Nishida, T. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.20.11812 · Cited by 56

A brain detoxifying enzyme for organophosphorus nerve poisons

Nomura, D. K., Leung, D., Chiang, K. P., Quistad, G. B., Cravatt, B. F., & Casida, J. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501915102 · Cited by 56

Cloning and Sequence Analysis of a Rat Liver cDNA Encoding Acyl-peptide Hydrolase

Kobayashi, K., Lin, L. H., Yeadon, J. E., Klickstein, L. B., & Smith, J. A. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)81877-4 · Cited by 54

Rat GP-3 is a pancreatic lipase with kinetic properties that differ from colipase-dependent pancreatic lipase

Jennens, M. L., & Lowe, M. E. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39718-2 · Cited by 54

Tumorigenicity of cell lines with altered lipid composition.

Roos, D. S., & Choppin, P. W. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.23.7622 · Cited by 54

Function, Activity, and Membrane Targeting of Cytosolic Phospholipase A2ζ in Mouse Lung Fibroblasts

Ghosh, M., Loper, R., Ghomashchi, F., Tucker, D. E., Bonventre, J. V., Gelb, M. H., & Leslie, C. C. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m608458200 · Cited by 54

Identification of the Expressed Form of Human Cytosolic Phospholipase A2β (cPLA2β)

Ghosh, M., Loper, R., Gelb, M. H., & Leslie, C. C. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601770200 · Cited by 53

Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors

Goodman, K. B., Bury, M. J., Cheung, M., Cichy-Knight, M. A., Dowdell, S. E., Dunn, A. K., Lee, D. M., Lieby, J. A., Moore, M. L., Scherzer, D. A., et al. (2008) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2008.11.033 · Cited by 53

Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363

Buchebner, M., Pfeifer, T., Rathke, N., Chandak, P. G., Lass, A., Schreiber, R., Kratzer, A., Zimmermann, R., Sattler, W., Köfeler, H. C., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m004259 · Cited by 52

Involvement of the peroxisome proliferator-activated receptor α in regulating long-chain acyl-CoA thioesterases

Hunt, M. C., Lindquist, P. J. G., Peters, J. M., Gonzalez, F. J., Diczfalusy, U., & Alexson, S. E. H. (2000) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32390-7 · Cited by 52

Vesicular Localization and Characterization of a Novel Post-Proline-Cleaving Aminodipeptidase, Quiescent Cell Proline Dipeptidase

Chiravuri, M., Agarraberes, F. A., Mathieu, S. L., Lee, H., & Huber, B. T. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.10.5695 · Cited by 51

Stimulus-dependent Deacylation of Bacterial Lipopolysaccharide by Dendritic Cells

Lu, M., Zhang, M., Kitchens, R. L., Fosmire, S. P., Takashima, A., & Munford, R. S. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030420 · Cited by 51

Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype

Dobrovolsky, V. N., Bowyer, J. F., Pabarcus, M. K., Heflich, R. H., Williams, L. D., Doerge, D. R., Arvidsson, B., Bergquist, J., & Casida, J. E. (2005) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2005.03.010 · Cited by 51

Acute Sarin Exposure Causes Differential Regulation of Choline Acetyltransferase, Acetylcholinesterase, and Acetylcholine Receptors in the Central Nervous System of the Rat

Khan, W. A. (2000) · Toxicological Sciences · doi:10.1093/toxsci/57.1.112 · Cited by 51

Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice

Ortega-Gutiérrez, S., Leung, D., Ficarro, S., Peters, E. C., & Cravatt, B. F. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002486 · Cited by 50

Arylacetamide deacetylase attenuates fatty-acid-induced triacylglycerol accumulation in rat hepatoma cells

Lo, V., Erickson, B., Thomason-Hughes, M., Ko, K. W. S., Dolinsky, V. W., Nelson, R. C., & Lehner, R. S. (2009) · Journal of Lipid Research · doi:10.1194/jlr.m000596 · Cited by 50

Esterases and autoimmunity: the Sialic acid acetylesterase pathway and the regulation of peripheral B cell tolerance

Pillai, S., Cariappa, A., & Pirnie, S. P. (2009) · Trends in immunology · doi:10.1016/j.it.2009.07.006 · Cited by 49

A vitellogenic‐like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles

Harris, J., Schwinn, N., Mahoney, J. A., Lin, H., Shaw, M. K., Howard, C. J., SILVA, R. P. D., & Gordon, S. (2006) · International Journal of Experimental Pathology · doi:10.1111/j.0959-9673.2006.00450.x · Cited by 49

Identification of Functional Domains of Rat Intestinal Phospholipase B/Lipase

Takemori, H., Zolotaryov, F. N., Lü, T., Tchoua, U., Komatsubara, T., Hatano, O., Okamoto, M., & Tojo, H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.4.2222 · Cited by 48

Identification, Genomic Organization, and mRNA Expression of LACTB, Encoding a Serine β-Lactamase-like Protein with an Amino-terminal Transmembrane Domain

Smith, T. S., Southan, C., Ellington, K., Campbell, D. S., Tew, D. G., & Debouck, C. M. (2001) · Genomics · doi:10.1006/geno.2001.6643 · Cited by 47

Molecular Cloning and Characterization of Two Mouse Peroxisome Proliferator-activated Receptor α (PPARα)-regulated Peroxisomal Acyl-CoA Thioesterases

Westin, M., Alexson, S. E. H., & Hunt, M. C. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313863200 · Cited by 47

Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on neuropeptide metabolism in the rat brain

Toide, K., Fujiwara, T., Iwamoto, Y., Shinoda, M., Okamiya, K., & Kato, T. (1996) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00168640 · Cited by 47

A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization

Wang, A., Yang, H., Friedman, P., Johnson, C., & Dennis, E. A. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00012-8 · Cited by 47

Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein

Du, H., Witte, D. P., & Grabowski, G. A. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42005-x · Cited by 47

Lipoamidase activity in normal and mutagenized pancreatic cholesterol esterase (bile salt-stimulated lipase)

Hui, D. Y., Hayakawa, K., & Oizumi, J. (1993) · Biochemical Journal · doi:10.1042/bj2910065 · Cited by 46

Familial lipoprotein lipase (LPL) deficiency: A catalogue of LPL gene mutations identified in 20 patients from the UK, Sweden, and Italy

Mailly, F., Palmen, J., Muller, D. P. R., Gibbs, T., Lloyd, J. K., Brunzell, J. D., Durrington, P. N., Mitropoulos, K., Betteridge, J. D., Watts, G. F., et al. (1997) · Human Mutation · doi:10.1002/(sici)1098-1004(1997)10:6<465::aid-humu8>3.0.co;2-c · Cited by 46

Getting a chemical handle on proteinpost-translational modification

Heal, W. P., & Tate, E. W. (2009) · Organic & Biomolecular Chemistry · doi:10.1039/b917894e · Cited by 46

Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2γ)

Yamashita, A., Tanaka, K., Kamata, R., 司紗, 熊., Suzuki, N., Koga, H., Waku, K., & Sugiura, T. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.05.008 · Cited by 45

Evidence for Hormone-Sensitive Lipase mRNA Expression in Human Monocyte/Macrophages

Reue, K., Cohen, R. D., & Schotz, M. C. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.12.3428 · Cited by 45

Serum High-Density Lipoprotein: Effect of Change in Structure on Activity of Chicken Adipose Tissue Lipase

Scanu, A. M. (1966) · Science · doi:10.1126/science.153.3736.640 · Cited by 44

Peptidomics of Prolyl Endopeptidase in the Central Nervous System

Nolte, W. M., Tagore, D. M., Lane, W. S., & Saghatelian, A. (2009) · Biochemistry · doi:10.1021/bi901637c · Cited by 43

Kynurenine formamidase: determination of primary structure and modeling-based prediction of tertiary structure and catalytic triad

Pabarcus, M. K., & Casida, J. E. (2002) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(02)00232-7 · Cited by 42

Golgi‐localized KIAA0725p regulates membrane trafficking from the Golgi apparatus to the plasma membrane in mammalian cells

Sato, S., Inoue, H., Kogure, T., Tagaya, M., & Tani, K. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.09.047 · Cited by 42

Ultrastructural localization of dipeptidylpeptidase IV in the glomerulum of the rat kidney

Kettmann, U., Humbel, B. M., & Holzhausen, H.-J. (1992) · Acta Histochemica · doi:10.1016/s0065-1281(11)80085-1 · Cited by 41

Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid‐β peptide

Yamin, R., Bagchi, S., Hildebrant, R., Scaloni, A., Widom, R. L., & Abraham, C. R. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04251.x · Cited by 41

Production of the Butyrylcholinesterase Knockout Mouse

Li, B., Duysen, E. G., Saunders, T. L., et al. (2006) · Journal of Molecular Neuroscience · doi:10.1385/jmn:30:1:193 · Cited by 41

Overexpression of Lysosomal Acid Lipase and Other Proteins in Atherosclerosis

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γ-Amino-Substituted Analogues of 1-[(S)-2,4-Diaminobutanoyl]piperidine as Highly Potent and Selective Dipeptidyl Peptidase II Inhibitors

Senten, K., der Veken, P. V., Meester, I. D., Lambeir, A., Scharpé, S., Haemers, A., & Augustyns, K. (2004) · Journal of Medicinal Chemistry · doi:10.1021/jm031122f · Cited by 40

Lysosomal and Cytosolic Sialic Acid 9-O-Acetylesterase Activities Can Be Encoded by One Gene via Differential Usage of a Signal Peptide-encoding Exon at the N Terminus

Takematsu, H., Diaz, S. L., Stoddart, A., Zhang, Y., & Varki, A. P. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.36.25623 · Cited by 40

Purification and Characterization of a Catalytic Domain of Rat Intestinal Phospholipase B/Lipase Associated with Brush Border Membranes

Tojo, H., Ichida, T., & Okamoto, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.4.2214 · Cited by 39

Cloning and Expression of a Novel Lysophospholipase Which Structurally Resembles Lecithin Cholesterol Acyltransferase

Taniyama, Y., Shibata, S., Kita, S., Horikoshi, K., Fuse, H., Shirafuji, H., Sumino, Y., & Fujino, M. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0411 · Cited by 39

The 2p21 deletion syndrome: Characterization of the transcription content

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Overproduction of Acyloxyacyl Hydrolase by Macrophages and Dendritic Cells Prevents Prolonged Reactions to Bacterial Lipopolysaccharide In Vivo

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Alternate Activation of Two Divergently Transcribed Mouse Genes from a Bidirectional Promoter Is Linked to Changes in Histone Modification

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Pancreatic lipase-related protein type I: a specialized lipase or an inactive enzyme

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Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties

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Peroxisomes Contain a Specific Phytanoyl-CoA/Pristanoyl-CoA Thioesterase Acting as a Novel Auxiliary Enzyme in α- and β-Oxidation of Methyl-branched Fatty Acids in Mouse

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Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)

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Cloning of a Novel Retinoid-inducible Serine Carboxypeptidase from Vascular Smooth Muscle Cells

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nmd, a novel gene differentially expressed in human melanoma cell lines, encodes a new atypical member of the enzyme family of lipases

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Infantile galactosialidosis presenting with congenital adrenal hyperplasia and renal hypertension

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In vivo multiplex quantitative analysis of 3 forms of alpha melanocyte stimulating hormone in pituitary of prolyl endopeptidase deficient mice

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The Crystal Structure of CCG1/TAFII250-interacting Factor B (CIB)

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Neurogenin 3-Specific Dipeptidyl Peptidase-2 Deficiency Causes Impaired Glucose Tolerance, Insulin Resistance, and Visceral Obesity

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Functional Characterization of a Putative Serine Carboxypeptidase in Vascular Smooth Muscle Cells

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α/β hydrolase 1 is upregulated in D5 dopamine receptor knockout mice and reduces O2- production of NADPH oxidase

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Crystal structure of human retinoblastoma binding protein 9

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Tissue Expression of the Novel Serine Carboxypeptidase Scpep1

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Characterization of lpd (lipid defect): a novel mutation on mouse chromosome 16 associated with a defect in triglyceride metabolism

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The biology and therapeutic targeting of the proprotein convertases

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Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack

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Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice

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DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

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How Chemoproteomics Can Enable Drug Discovery and Development

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