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H2O2 induces PP2A demethylation to downregulate mTORC1 signaling in HEK293 cells

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Rules for PP2A-controlled phosphosignalling and drug responsesPreprint

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Expression Pattern and Prognostic Utility of PME-1 in Patients with Hepatocellular Carcinoma

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Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice

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Hydrogen peroxide redistributes the localization of protein phosphatase methylesterase 1

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Transcriptome analysis revealed that PME-1 suppresses inflammatory signaling, activates PI3K/Akt signaling, and promotes epithelial-mesenchymal transition

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Network‐based analysis predicts interacting genetic modifiers from a meta‐mapping study of spike–wave discharge in mice

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Two Distinct Mechanisms of PP2A Regulation by Methylesterase PME ‐1 Are Both Essential for Mouse Development

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Beyond cartilage degeneration: osteoarthritis as a systems failure of inflammation regulation

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Probe Development Efforts to Identify Novel Inhibitors of Protein Phosphatase Methylesterase-1 (PME-1)

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Regulation of protein phosphatase 2A by proteasomal degradation

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SERINE/THREONINE PHOSPHATASES: ROLE IN SPERMATOGENESIS AND SPERM FUNCTION

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Structural Studies on PP2A and Methods in Protein Production

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Regulation of PP2Ac stability – discovery of a novel α4 monoubiquitination-dependent mechanism that is altered in Alzheimer’s disease

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Cryo-EM and cellular dissection uncover versatile PME-1 activities in PP2A holoenzyme demethylation and inhibitionPreprint

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Phosphatase regulation in cardiovascular physiology and disease

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Targeted Disruption of the PME-1 Gene Causes Loss of Demethylated PP2A and Perinatal Lethality

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Two Distinct Mechanisms of PP2A Regulation by Methylesterase PME ‐1 Are Both Essential for Mouse Development

Ikeda, S., Ando, S., Kishida, N., Tanaka, K., Sakurai, M., Sakai, Y., Ayabe, S., Mizuno‐Iijima, S., Yoshiki, A., Nakashima, K., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202402617rr · Cited by 1 · see citing works

Protein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome Degradation

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RESEARCH ARTICLE Protein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome Degradation

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A stable association with PME ‐1 may be dispensable for PP 2A demethylation – implications for the detection of PP 2A methylation and immunoprecipitation

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