Mechanism of Rubisco: the carbamate as general base
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of Rubisco: The Carbamate as General Base✗W. Wallace Cleland, T. John Andrews, Steven Gutteridge, Fred C. Hartman, and George H. LorimerView Author Information The Institute for Enzyme Research, University of Wisconsin, Madison, Wisconsin 53705, Research School of Biological Sciences, Australian National University, Canberra 2601, Australia, Central Research and Development Department, Dupont Company, Experimental Station, Wilmington, Delaware 19880-0402, and Protein Engineering Program, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-8077 Cite this: Chem. Rev. 1998, 98, 2, 549–562Publication Date (Web):March 12, 1998Publication History Received20 February 1997Revised19 November 1997Published online12 March 1998Published inissue 1 April 1998https://pubs.acs.org/doi/10.1021/cr970010rhttps://doi.org/10.1021/cr970010rresearch-articleACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views4047Altmetric-Citations338LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Metals,Organic compounds,Oxygen,Phosphates,Reaction mechanisms Get e-Alerts
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Rubisco must first be carbamylated by the addition of a CO2 molecule at the active-site Lys in order to have activity.
“Rubisco must first be carbamylated by the addition of a CO 2 molecule at the activesite Lys in order to have activity (Cleland et al., 1998).”
From Responses of<i>Nannochloropsis oceanica</i>IMET1 to Long-Term Nitrogen Starvation and Recovery (2013) · cites this paper as Cleland et al., 1998
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- Authors
- Cleland, W. W., Andrews, T. J., Gutteridge, S., Hartman, F. C., & Lorimer, G. H.
- Affiliations
- Australian National University (AU)
- Corresponding author
- Lorimer, George H.
- ORCID
- Lorimer, George H.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 1998-03-12
- Volume
- 98
- Issue
- 2
- Pages
- 549-562
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2039132912
- Cited by
- 430
- References
- 97
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 10 · 2023: 15 · 2022: 16 · 2021: 15 · 2020: 16 · 2019: 22 · 2018: 21 · 2017: 20 · 2016: 21 · 2015: 13 · 2014: 9 · 2013: 24 · 2012: 16
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Reaction Mechanisms
- Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Catalyzed Oxygenation Mechanisms
- Keywords
- Rubisco, carbamates, general base, enzyme mechanism, carboxylation, oxygenation, catalytic mechanism
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