The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies
Abstract
Spirooxindoles have become a privileged skeleton given their broad and promising activities in various therapeutic areas. The strategies and catalyst systems described here highlight recent advances in the enantioselective synthesis of spirooxindoles via organocascade strategies. Various organocatalysts with distinct activation modes have found application in constructing these sophisticated compounds. This review focuses on the enantioselective synthesis of spirooxindoles via organocascade strategies and is organized on the basis of three primary starting materials and then further subdivided according to the types of organocatalyst. These methods are of importance for the synthesis of complex natural products and the design of new pharmaceutical compounds. We believe that compounds based on spirooxindole skeletons have the potential to provide novel therapeutic agents and useful biological tools.
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Shangary, S., Qin, D., McEachern, D., Liu, M., Miller, R. S., Qiu, S., Nikolovska-Coleska, Z., Ding, K., Wang, G., Chen, J., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708917105 · Cited by 660
Structure-based design of potent non-peptide MDM2 inhibitors
Ding, K., Lu, Y., Nikolovska-Coleska, Z., Qiu, S., Ding, Y., Gao, W., Stuckey, J., Krajewski, K., Roller, P. P., Tomita, Y., et al. (2005) · Journal of the American Chemical Society · doi:10.1021/ja051147z · Cited by 657
Cited by
Catalytic asymmetric synthesis of spirooxindoles: recent developments
Mei, G.-J., & Shi, F. (2018) · Chemical Communications · doi:10.1039/c8cc02364f · Cited by 467
Recent advances in the synthesis of biologically active spirooxindoles
Santos, M. M. M. (2014) · Tetrahedron · doi:10.1016/j.tet.2014.08.005 · Cited by 398
Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters
Xu, P.-W., Yu, J.-S., Chen, C., Cao, Z.-Y., Zhou, F., & Zhou, J. (2019) · ACS Catalysis · doi:10.1021/acscatal.8b03694 · Cited by 325
All-carbon quaternary centers in natural products and medicinal chemistry: recent advances
Ling, T., & Rivas, F. (2016) · Tetrahedron · doi:10.1016/j.tet.2016.09.002 · Cited by 312
Dalpozzo, R. (2017) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.201700361 · Cited by 146
Wang, B., Peng, F., Huang, W., Zhou, J., Zhang, N., Sheng, J., Haruehanroengra, P., He, G., & Han, B. (2020) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2019.12.013 · Cited by 73
Metadata
- Authors
- Cheng, D., Ishihara, Y., Tan, B., & Barbas, C. F.
- Venue
- ACS Catalysis
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-02-03
- Volume
- 4
- Issue
- 3
- Pages
- 743-762
- ISSN
- 2155-5435 (ISSN-L)
- OpenAlex
- W2131765906
- Cited by
- 856
- References
- 2
- FWCI
- 49.43
- Type
- journal article
- Language
- en
- Open access
- closed
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