The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters
Abstract
The catalytic enantioselective assembly of spirocyclic molecules featuring a spiro quaternary carbon stereocenter is currently of great interest because such privileged 3D structures are widely present in natural products that exhibit a broad spectrum of biological and pharmacological activities. This review summarizes the advances based on six major synthetic strategies and showcases the reaction mechanisms in detail. The advantages and limitations of each synthetic strategy are presented, and the remaining synthetic opportunities are outlined.
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Cites
Galliford, C. V., & Scheidt, K. A. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200701342 · Cited by 2,429
Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks
Singh, G. S., & Desta, Z. Y. (2012) · Chemical Reviews · doi:10.1021/cr300135y · Cited by 1,601
Privileged scaffolds for library design and drug discovery
Welsch, M. E., Snyder, S. A., & Stockwell, B. R. (2010) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2010.02.018 · Cited by 1,509
Marti, C., & Carreira, E. M. (2003) · European Journal of Organic Chemistry · doi:10.1002/ejoc.200300050 · Cited by 1,455
The use of spirocyclic scaffolds in drug discovery
Zheng, Y., Tice, C. M., & Singh, S. B. (2014) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2014.06.081 · Cited by 1,036
Galloway, W. R. J. D., Isidro-Llobet, A., & Spring, D. R. (2010) · Nature Communications · doi:10.1038/ncomms1081 · Cited by 891
Spirooxindoles: Promising scaffolds for anticancer agents
Yu, B., Yu, D.-Q., & Liu, H.-M. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.06.056 · Cited by 867
Cheng, D., Ishihara, Y., Tan, B., & Barbas, C. F. (2014) · ACS Catalysis · doi:10.1021/cs401172r · Cited by 856
Liu, Y., Han, S.-J., Liu, W.-B., & Stoltz, B. M. (2015) · Accounts of Chemical Research · doi:10.1021/ar5004658 · Cited by 825
Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters
Zeng, X.-P., Cao, Z.-Y., Wang, Y.-H., Zhou, F., & Zhou, J. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00094 · Cited by 807
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Metadata
- Authors
- Xu, P.-W., Yu, J.-S., Chen, C., Cao, Z.-Y., Zhou, F., & Zhou, J.
- Venue
- ACS Catalysis
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-01-31
- Volume
- 9
- Issue
- 3
- Pages
- 1820-1882
- ISSN
- 2155-5435 (ISSN-L)
- OpenAlex
- W2913484133
- Cited by
- 325
- References
- 118
- FWCI
- 18.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- Xu, P.-W., Yu, J.-S., Chen, C., Cao, Z.-Y., Zhou, F., & Zhou, J. (2019). Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters. ACS Catalysis. https://doi.org/10.1021/acscatal.8b03694
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