The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Exposure Assessment and Risk Characterization for Perfluorooctanoate in Selected Consumer Articles
Abstract
An exposure assessment and risk characterization was conducted to better understand the potential human health significance of trace levels of perfluorooctanoate (PFO) detected in certain consumer articles. PFO is the anion of perfluorooctanoic acid (PFOA). Concentrations of PFO in the consumer articles were determined from extraction tests and product formulation information. Potential exposures during consumer use of the articles were quantified based on an assessment of behavior patterns and regulatory guidance. Health benchmarks were developed and then compared to the exposure estimates to yield margins of exposure (MOEs). A simple one-compartment model was also developed to estimate contributions of potential consumer exposures to PFO concentrations in serum. While there are considerable uncertainties in this assessment, it indicates that exposures to PFO during consumer use of the articles evaluated in this study are not expected to cause adverse human health effects in infants, children, adolescents, adult residents, or professionals nor result in quantifiable levels of PFO in human serum.
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Citations
Cites
Organofluorine Chemistry: Principles and Commercial Applications
(1994) · doi:10.1007/978-1-4899-1202-2 · Cited by 1,691
The toxicology of perfluorooctanoate
Kennedy, G. L., Butenhoff, J. L., Olsen, G. W., O'Connor, J. C., Seacat, A. M., Perkins, R. G., Biegel, L. B., Murphy, S. R., & Farrar, D. G. (2004) · Critical Reviews in Toxicology · doi:10.1080/10408440490464705 · Cited by 742
Cited by
Buck, R. C., Franklin, J., Berger, U., Conder, J. M., Cousins, I. T., de Voogt, P., Jensen, A. A., Kannan, K., Mabury, S. A., & van Leeuwen, S. P. (2011) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.258 · Cited by 4,641
Self-citationRisk to human health related to the presence of perfluoroalkyl substances in food
Panel), E. P. O. C. I. T. F. C. (. C., Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl‐Kraupp, B., Hogstrand, C., Hoogenboom, L. (., Leblanc, J., et al. (2020) · EFSA Journal · doi:10.2903/j.efsa.2020.6223 · Cited by 989
Post, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639
Perfluoroalkyl and polyfluoroalkyl substances in consumer products
Kotthoff, M., Müller, J., Jürling, H., Schlummer, M., & Fiedler, D. (2015) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4202-7 · Cited by 613
Estimating Consumer Exposure to PFOS and PFOA
Trudel, D., Horowitz, L., Wormuth, M., Scheringer, M., Cousins, I. T., & Hungerbühler, K. (2008) · Risk Analysis · doi:10.1111/j.1539-6924.2008.01017.x · Cited by 514
Metadata
- Authors
- Washburn, S. T., Bingman, T. S., Braithwaite, S. K., Buck, R. C., Buxton, L. W., Clewell, H. J., Haroun, L. A., Kester, J. E., Rickard, R. W., & Shipp, A. M.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-04-20
- Volume
- 39
- Issue
- 11
- Pages
- 3904-3910
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2023219219
- Cited by
- 163
- References
- 2
- FWCI
- 8.14
- Type
- journal article
- Language
- en
- Open access
- closed
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