The toxicology of perfluorooctanoate

Pancreatic Cancer

Spencer, P. M., Cameron, J. L., & Lin, L. (2000) · Cited by 7,202 · see citing works

Cancer Epidemiology and Prevention

Breslow, L. (1997) · JAMA · doi:10.1001/jama.1997.03550210090050 · Cited by 1,428 · see citing works

Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices

Hansen, K. J., Clemen, L. A., Ellefson, M. E., & Johnson, H. O. (2001) · Environmental Science & Technology · doi:10.1021/es001489z · Cited by 923 · see citing works

PPARα Agonist-Induced Rodent Tumors: Modes of Action and Human Relevance

Klaunig, J. E., Babich, M. A., Baetcke, K. P., Cook, J. C., Corton, J. C., David, R. M., DeLuca, J. G., Lai, D. Y., McKee, R. H., Peters, J. M., et al. (2003) · Critical Reviews in Toxicology · doi:10.1080/713608372 · Cited by 611 · see citing works

Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643

Peters, J. (1997) · Carcinogenesis · doi:10.1093/carcin/18.11.2029 · Cited by 484 · see citing works

Peroxisome proliferator activated receptor-alpha expression in human liver.

Palmer, C. N., Hsu, M. H., Griffin, K. J., Raucy, J. L., & Johnson, E. F. (1998) · PubMed · Cited by 448 · see citing works

Body weight and food intake as initiating factors for puberty in the rat

Kennedy, G. C., & Mitra, J. (1963) · The Journal of Physiology · doi:10.1113/jphysiol.1963.sp007112 · Cited by 443 · see citing works

Peroxisome Proliferator Activated Receptor-α Expression in Human Liver

Palmer, C. N. A., Hsu, M.-H., Griffin, K. J., Raucy, J. L., & Johnson, E. F. (1998) · Molecular Pharmacology · doi:10.1124/mol.53.1.14 · Cited by 416 · see citing works

Binding of Perfluorooctanoic Acid to Rat and Human Plasma Proteins

Han, X., Snow, T. A., Kemper, R. A., & Jepson, G. W. (2003) · Chemical Research in Toxicology · doi:10.1021/tx034005w · Cited by 411 · see citing works

Perfluorooctanesulfonate and other fluorochemicals in the serum of American Red Cross adult blood donors.

Olsen, G. W., Church, T. R., Miller, J. P., Burris, J. M., Hansen, K. J., Lundberg, J. K., Armitage, J. B., Herron, R., Medhdizadehkashi, Z., Nobiletti, J. B., et al. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6316 · Cited by 401 · see citing works

Some effects of accelerating growth - I. General somatic development

Widdowson, E. M., & McCance, R. A. (1960) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1960.0032 · Cited by 382 · see citing works

trans-Activation of PPARα and PPARγ by Structurally Diverse Environmental Chemicals

Maloney, E. K., & Waxman, D. J. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8809 · Cited by 375 · see citing works

Epidemiologic Assessment of Worker Serum Perfluorooctanesulfonate (PFOS) and Perfluorooctanoate (PFOA) Concentrations and Medical Surveillance Examinations

Olsen, G. W., Burris, J. M., Burlew, M., & Mandel, J. H. (2003) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000052958.59271.10 · Cited by 362 · see citing works

Mechanisms of Extrahepatic Tumor Induction by Peroxisome Proliferators in Male CD Rats

Biegel, L. B., Hurtt, M. E., Frame, S. R., O’Connor, J. C., & Cook, J. C. (2001) · Toxicological Sciences · doi:10.1093/toxsci/60.1.44 · Cited by 349 · see citing works

A Cancer Risk Assessment of Di(2-ethylhexyl)phthalate: Application of the New U.S. EPA Risk Assessment Guidelines

Doull, J., Cattley, R. C., Elcombe, C. R., Lake, B. G., Swenberg, J. A., Wilkinson, C., Williams, G. M., & van Gemert, M. (1999) · Regulatory Toxicology and Pharmacology · doi:10.1006/rtph.1999.1296 · Cited by 337 · see citing works

Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis

Ashby, J., Brady, A. M., Elcombe, C. R., ELLIOTT, B. M., Ishmael, J., Odum, J., Tugwood, J. D., Kettle, S., & Purchase, I. F. H. (1994) · Human & Experimental Toxicology · doi:10.1177/096032719401300201 · Cited by 312 · see citing works

Sex hormone-regulated renal transport of perfluorooctanoic acid

Kudo, N., Katakura, M., Sato, Y., & Kawashima, Y. (2002) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(02)00006-6 · Cited by 293 · see citing works

Tissue distribution, metabolism, and elimination of perfluorooctanoic acid in male and female rats

Heuvel, J. P. V., Kuslikis, B. I., Rafelghem, M. J. V., & Peterson, R. E. (1991) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.2570060202 · Cited by 289 · see citing works

The Effect of Atrazine on Puberty in Male Wistar Rats: An Evaluation in the Protocol for the Assessment of Pubertal Development and Thyroid Function

Stoker, T. E. (2000) · Toxicological Sciences · doi:10.1093/toxsci/58.1.50 · Cited by 272 · see citing works

Hepatic peroxisome proliferation in rodents and its significance for humans

Bentley, P., Calder, I. C., Elcombe, C. R., GRASSO, P., Stringer, D. A., & Wiegand, H.-J. (1993) · Food and Chemical Toxicology · doi:10.1016/0278-6915(93)90225-n · Cited by 271 · see citing works

Lipid‐lowering drugs and mitochondrial function: effects of HMG‐CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio

DE PINIEUX, G., CHARIOT, P., AMMI‐SAÏD, M., LOUARN, F., LEJONC, J. L., ASTIER, A., JACOTOT, B., & GHERARDI, R. (1996) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1996.04178.x · Cited by 262 · see citing works

Toxicity of Ammonium Perfluorooctanoate in Male Cynomolgus Monkeys after Oral Dosing for 6 Months

Butenhoff, J. L. (2002) · Toxicological Sciences · doi:10.1093/toxsci/69.1.244 · Cited by 259 · see citing works

Evidence that there are Two Forms of Fluoride in Human Serum

Taves, D. R. (1968) · Nature · doi:10.1038/2171050b0 · Cited by 253 · see citing works

Comparison of the toxicokinetics between perfluorocarboxylic acids with different carbon chain length

Ohmori, K., Kudo, N., Katayama, K., & Kawashima, Y. (2002) · Toxicology · doi:10.1016/s0300-483x(02)00573-5 · Cited by 251 · see citing works

Receptor and Nonreceptor-Mediated Organ-Specific Toxicity of Di(2-ethylhexyl)phthalate (DEHP) in Peroxisome Proliferator-Activated Receptorα-Null Mice

Ward, J. M., Peters, J. M., Perella, C. M., & Gonzalez, F. J. (1998) · Toxicologic Pathology · doi:10.1177/019262339802600208 · Cited by 249 · see citing works

Perfluorooctanoate, perflourooctanesulfonate, and N-ethyl perfluorooctanesulfonamido ethanol; peroxisome proliferation and mitochondrial biogenesis

Berthiaume, J., & Wallace, K. B. (2002) · Toxicology Letters · doi:10.1016/s0378-4274(01)00466-0 · Cited by 246 · see citing works

Human Donor Liver and Serum Concentrations of Perfluorooctanesulfonate and Other Perfluorochemicals

Olsen, G. W., Hansen, K. J., Stevenson, L. A., Burris, J. M., & Mandel, J. H. (2003) · Environmental Science & Technology · doi:10.1021/es020955c · Cited by 242 · see citing works

Do Peroxisome Proliferating Compounds Pose a Hepatocarcinogenic Hazard to Humans?

Cattley, R. C., DeLuca, J. G., Elcombe, C. R., Fenner-Crisp, P. A., Lake, B. G., Marsman, D. S., Pastoor, T. A., Popp, J. A., Robinson, D. E., Schwetz, B. A., et al. (1998) · Regulatory Toxicology and Pharmacology · doi:10.1006/rtph.1997.1163 · Cited by 242 · see citing works

Effects of Ammonium Perfluorooctanoate on Leydig-Cell Function: In Vitro, in Vivo, and ex Vivo Studies

Biegel, L. B., Liu, R. C. M., Hurtt, M. E., & Cook, J. C. (1995) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1995.1164 · Cited by 215 · see citing works

Structural Determinants of Fluorochemical-Induced Mitochondrial Dysfunction

Starkov, A. A. (2002) · Toxicological Sciences · doi:10.1093/toxsci/66.2.244 · Cited by 208 · see citing works

Comparison of the elimination between perfluorinated fatty acids with different carbon chain length in rats

Kudo, N., Suzuki, É., Katakura, M., Ohmori, K., Noshiro, R., & Kawashima, Y. (2001) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(01)00155-7 · Cited by 205 · see citing works

Endocrine-Disrupting Chemicals: Prepubertal Exposures and Effects on Sexual Maturation and Thyroid Activity in the Female Rat. A Focus on the EDSTAC Recommendations

Goldman, J., Laws, S., Balchak, S. K., Cooper, R., & Kavlock, R. (2000) · Critical Reviews in Toxicology · doi:10.1080/10408440091159185 · Cited by 200 · see citing works

Rodent Leydig Cell Tumorigenesis: A Review of the Physiology, Pathology, Mechanisms, and Relevance to Humans

Cook, J. C., Klinefelter, G. R., Hardisty, J. F., Sharpe, R. M., & Foster, P. M. D. (1999) · Critical Reviews in Toxicology · doi:10.1080/10408449991349203 · Cited by 195 · see citing works

Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, Washington

Olsen, G. W., Church, T. R., Larson, E. B., van Belle, G., Lundberg, J. K., Hansen, K. J., Burris, J. M., Mandel, J. H., & Zobel, L. R. (2003) · Chemosphere · doi:10.1016/j.chemosphere.2003.09.025 · Cited by 191 · see citing works

The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat

Butenhoff, J. L., Kennedy, G. L., Frame, S. R., O’Connor, J. C., & York, R. G. (2004) · Toxicology · doi:10.1016/j.tox.2003.11.005 · Cited by 188 · see citing works

Mitochondrial medicine--molecular pathology of defective oxidative phosphorylation.

Fosslien, E. (2001) · PubMed · Cited by 186 · see citing works

Endocrine-Disrupting Chemicals: Prepubertal Exposures and Effects on Sexual Maturation and Thyroid Function in the Male Rat. A Focus on the EDSTAC Recommendations

Stoker, T., Parks, L., Gray, L., & Cooper, R. (2000) · Critical Reviews in Toxicology · doi:10.1080/10408440091159194 · Cited by 185 · see citing works

Mortality Among Employees of a Perfluorooctanoic Acid Production Plant

Gilliland, F. D., & Mandel, J. S. (1993) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-199309000-00020 · Cited by 183 · see citing works

Inhibition of gap junctional intercellular communication by perfluorinated fatty acids is dependent on the chain length of the fluorinated tail

Upham, B. L., Deocampo, N. D., Wurl, B., & Trosko, J. E. (1998) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19981109)78:4 · Cited by 180 · see citing works

Mortality of employees of a perfluorooctanesulphonyl fluoride manufacturing facility

Alexander, B. H., Olsen, G. W., Burris, J. M., Mandel, J. H., & Mandel, J. S. (2003) · Occupational and Environmental Medicine · doi:10.1136/oem.60.10.722 · Cited by 179 · see citing works

PPAR: a mediator of peroxisome proliferator action

Green, S. (1995) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(95)00136-0 · Cited by 176 · see citing works

The acute toxicity of perfluorooctanoic and perfluorodecanoic acids in male rats and effects on tissue fatty acids

Olson, C. T., & Andersen, M. E. (1983) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(83)90154-0 · Cited by 172 · see citing works

The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid

Haughom, B., & Spydevold, Ø. S. (1992) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(92)90258-w · Cited by 172 · see citing works

An Epidemiologic Investigation of Reproductive Hormones in Men with Occupational Exposure to Perfluorooctanoic Acid

Olsen, G. W., Gilliland, F. D., Burlew, M., Burris, J. M., Mandel, J. S., & Mandel, J. H. (1998) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-199807000-00006 · Cited by 169 · see citing works

Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid

Yang, Q., Abedi‐Valugerdi, M., Xie, Y., Zhao, X., Möller, G., Nelson, B. D., & DePierre, J. W. (2002) · International Immunopharmacology · doi:10.1016/s1567-5769(01)00164-3 · Cited by 169 · see citing works

Reactive Oxygen Species and Mitochondria Mediate the Induction of Apoptosis in Human Hepatoma HepG2 Cells by the Rodent Peroxisome Proliferator and Hepatocarcinogen, Perfluorooctanoic Acid

Panaretakis, T., Shabalina, I. G., Grandér, D., Shoshan, M. C., & DePierre, J. W. (2001) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9159 · Cited by 168 · see citing works

Mechanisms of Hepatocarcinogenicity of Peroxisome-Proliferating Drugs and Chemicals

Lake, B. G. (1995) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.35.040195.002411 · Cited by 168 · see citing works

The Induction of Peroxisome Proliferation in Rat Liver by Perfluorinated Fatty Acids, Metabolically Inert Derivatives of Fatty Acids

Ikeda, T., Aiba, K., FUKUDA, K., & Tanaka, M. (1985) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a135302 · Cited by 165 · see citing works

Cholestyramine-enhanced fecal elimination of carbon-14 in rats after administration of ammonium 614C9perfluorooctanoate or potassium 614C9perfluorooctanesulfonate

JOHNSON, J. (1984) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(84)90235-5 · Cited by 161 · see citing works

PLASMA CHOLECYSTOKININ AND HEPATIC ENZYMES, CHOLESTEROL AND LIPOPROTEINS IN AMMONIUM PERFLUOROOCTANOATE PRODUCTION WORKERS

Olsen, G. W., Burris, J. M., Burlew, M., & Mandel, J. H. (2000) · Drug and Chemical Toxicology · doi:10.1081/dct-100101973 · Cited by 147 · see citing works

Effects of peroxisome proliferators on the thymus and spleen of mice

Yang, Q., Xie, Y., & DePierre, J. W. (2000) · Clinical & Experimental Immunology · doi:10.1046/j.1365-2249.2000.01367.x · Cited by 143 · see citing works

Malignant Tumors in Rats Fed Nafenopin, a Hepatic Peroxisome Proliferator 2

Reddy, J. K., & Rao, M. S. (1977) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/59.6.1645 · Cited by 142 · see citing works

Induction of leydig cell adenomas by ammonium perfluorooctanoate: A possible endocrine-related mechanism

Cook, J. C., Murray, S. M., Frame, S. R., & Hurtt, M. E. (1992) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(92)90116-a · Cited by 140 · see citing works

Characterization of risk for general population exposure to perfluorooctanoate

Butenhoff, J. L., Gaylor, D. W., Moore, J. A., Olsen, G. W., Rodricks, J. V., Mandel, J. H., & Zobel, L. R. (2004) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2004.03.003 · Cited by 139 · see citing works

Health status of plant workers exposed to fluorochemicals - a preliminary report

UBEL, F. A., SORENSON, S. D., & Roach, D. E. (1980) · American Industrial Hygiene Association Journal · doi:10.1080/15298668091425310 · Cited by 135 · see citing works

Tumors in male rats fed ethyl chlorophenoxyisobutyrate, a hypolipidemic drug.

Svoboda, D. J., & Azarnoff, D. L. (1979) · PubMed · Cited by 134 · see citing works

Leydig cell hyperplasia and adenoma formation: Mechanisms and relevance to humans

Clegg, E. D., Cook, J. C., Chapin, R. E., Foster, P. M. D., & Daston, G. P. (1997) · Reproductive Toxicology · doi:10.1016/s0890-6238(96)00203-1 · Cited by 134 · see citing works

Involvement of the Peroxisome Proliferator-Activated Receptor Alpha in the Immunomodulation Caused by Peroxisome Proliferators in Mice

Yang, Q., Xie, Y., Alexson, S. E. H., Dean Nelson, B., & DePierre, J. W. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)00923-1 · Cited by 131 · see citing works

Peroxisomes: Biology and Importance in Toxicology and Medicine

Lake, R. (2007) · Cited by 131 · see citing works

SEXUAL MATURATION DATA FOR CRL SPRAGUE-DAWLEY RATS: CRITERIA AND CONFOUNDING FACTORS

Lewis, E. M., Barnett, J. F., Freshwater, L., Hoberman, A. M., & Christian, M. S. (2002) · Drug and Chemical Toxicology · doi:10.1081/dct-120014794 · Cited by 128 · see citing works

Animal toxicity studies with ammonium perfluorooctanoate

GRIFFITH, F. D., & Long, J. E. (1980) · American Industrial Hygiene Association Journal · doi:10.1080/15298668091425301 · Cited by 123 · see citing works

Expression of Transforming Growth Factor α (TGFα) in Differentiated Rat Mammary Tumors: Estrogen Induction of TGFα Production

Liu, S. C., Sanfilippo, B., Perroteau, I., Derynck, R., Salomon, D. S., & Kidwell, W. R. (1987) · Molecular Endocrinology · doi:10.1210/mend-1-10-683 · Cited by 120 · see citing works

Serum perfluorooctanoic acid and hepatic enzymes, lipoproteins, and cholesterol: A study of occupationally exposed men

Gilliland, F. D., & Mandel, J. S. (1996) · American Journal of Industrial Medicine · doi:10.1002/(sici)1097-0274(199605)29:5 · Cited by 120 · see citing works

Further evidence for the involvement of inhibition of cell proliferation and development in thymic and splenic atrophy induced by the peroxisome proliferator perfluoroctanoic acid in mice33Abbreviations: PFOA, perfluorooctanoic acid; PP, peroxisome proliferator; FBS, fetal bovine serum; FITC, fluorescein isothiocyanate; and DEHP, di(2-ethylhexyl)phthalate.

Yang, Q., Xie, Y., Eriksson, A. M., Nelson, B. D., & DePierre, J. W. (2001) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00752-3 · Cited by 115 · see citing works

Effects of Di-isononyl Phthalate, Di-2-ethylhexyl Phthalate, and Clofibrate in Cynomolgus Monkeys

Pugh, G. (2000) · Toxicological Sciences · doi:10.1093/toxsci/56.1.181 · Cited by 111 · see citing works

Quantitative Evaluation of Perfluorooctanesulfonate (PFOS) and Other Fluorochemicals in the Serum of Children

Olsen, G. W., Church, T. R., Hansen, K. J., Burris, J. M., Butenhoff, J. L., Mandel, J. H., & Zobel, L. R. (2004) · Journal of Children s Health · doi:10.3109/15417060490447378 · Cited by 110 · see citing works

Promotive effects of steroids and bile acids on hepatocarcinogenesis initiated by diethylnitrosamine.

Cameron, R., Imaida, K., Tsuda, H., & Ito, N. (1982) · PubMed · Cited by 108 · see citing works

The Sex-Related Difference in Perfluorooctanoate Excretion in the Rat

Hanhijärvi, H., Ophaug, R. H., & Singer, L. (1982) · Experimental Biology and Medicine · doi:10.3181/00379727-171-41476 · Cited by 102 · see citing works

Biochemistry Involving Carbon-Fluorine Bonds

Filler1, R. (1976) · ACS symposium series · doi:10.1021/bk-1976-0028 · Cited by 102 · see citing works

Peroxisome proliferator-activated receptors (PPARS) and carcinogenesis

Heuvel, J. P. V. (1999) · Toxicological Sciences · doi:10.1093/toxsci/47.1.1 · Cited by 99 · see citing works

Uncoupling of Monooxygenation and Electron Transport by Flurocarbons in Liver Microsomes

Ullrich, V., & Diehl, H. A. (1971) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1971.tb01420.x · Cited by 98 · see citing works

Nutritional influences on sexual maturation in the rat.

Glass, A. R., & Swerdloff, R. S. (1980) · PubMed · Cited by 95 · see citing works

Biochemical and morphological studies of ammonium perfluorooctanoate-induced hepatomegaly and peroxisome proliferation

Pastoor, T. P., Lee, K. P., Perri, M. A., & Gillies, P. J. (1987) · Experimental and Molecular Pathology · doi:10.1016/0014-4800(87)90011-6 · Cited by 93 · see citing works

HMG CoA Reductase Inhibitor-Induced Myotoxicity: Pravastatin and Lovastatin Inhibit the Geranylgeranylation of Low-Molecular-Weight Proteins in Neonatal Rat Muscle Cell Culture

Flint, O. P., Masters, B. A., Gregg, R. E., & Durham, S. K. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1997.8174 · Cited by 92 · see citing works

In vitro effects of melatonin on cell proliferation in a colon adenocarcinoma line

Farriol, M., Venereo, Y., Orta, X., Castellanos, J. M., & Segovia‐Silvestre, T. (2000) · Journal of Applied Toxicology · doi:10.1002/(sici)1099-1263(200001/02)20:1 · Cited by 91 · see citing works

Covalent binding of perfluorinated fatty acids to proteins in the plasma, liver and testes of rats

Vanden Heuvel, J. P., Kuslikis, B. I., & Peterson, R. E. (1992) · Chemico-Biological Interactions · doi:10.1016/0009-2797(92)90003-4 · Cited by 84 · see citing works

Determination of Acidity Constants of Perfluoroalkanoic Acids

Moroi, Y., Yano, H., Shibata, O., & Yonemitsu, T. (2001) · Bulletin of the Chemical Society of Japan · doi:10.1246/bcsj.74.667 · Cited by 83 · see citing works

Undernutrition, Puberty and the Development of Estrogen Positive Feedback in the Female Rat1

Rønnekleiv, O. K., Ojeda, S. R., & McCann, S. M. (1978) · Biology of Reproduction · doi:10.1095/biolreprod19.2.414 · Cited by 80 · see citing works

Effect of the Peroxisome Proliferator, Ammonium Perfluorooctanoate (C8), on Hepatic Aromatase Activity in Adult Male Crl:CD BR (CD) Rats

Liu, R. C. M. (1996) · Fundamental and Applied Toxicology · doi:10.1006/faat.1996.0059 · Cited by 78 · see citing works

Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta- estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor

Marty, M. S. (1999) · Toxicological Sciences · doi:10.1093/toxsci/52.2.269 · Cited by 78 · see citing works

The modulation of rat liver carcinogenesis by perfluorooctanoic acid, a peroxisome proliferator

ABDELLATIF, A. (1991) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(91)90257-f · Cited by 76 · see citing works

Subchronic Toxicity of Di(2-ethylhexyl)phthalate in Common Marmosets: Lack of Hepatic Peroxisome Proliferation, Testicular Atrophy, or Pancreatic Acinar Cell Hyperplasia,

Kurata, Y. (1998) · Toxicological Sciences · doi:10.1006/toxs.1997.2414 · Cited by 76 · see citing works

Short-term exposure to the peroxisome proliferators, perfluorooctanoic acid and perfluorodecanoic acid, causes significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats

Takagi, A., Sai, K., Umemura, T., Hasegawa, R., & Kurokawa, Y. (1991) · Cancer Letters · doi:10.1016/0304-3835(91)90063-n · Cited by 72 · see citing works

Metabolic Handling of Perfluorooctanoic Acid in Rats

Ophaug, R. H., & Singer, L. (1980) · Experimental Biology and Medicine · doi:10.3181/00379727-163-40715 · Cited by 72 · see citing works

Disposition of perfluorooctanoic acid in the rat after single and subchronic administration

Ylinen, M., Kojo, A., Hanhijärvi, H., & Peura, P. (1990) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf01702360 · Cited by 68 · see citing works

The Direct Effect of Hepatic Peroxisome Proliferators on Rat Leydig Cell Functionin Vitro

Liu, R. (1996) · Fundamental and Applied Toxicology · doi:10.1006/faat.1996.0047 · Cited by 67 · see citing works

Sex-related difference in the inductions by perfluoro-octanoic acid of peroxisomal β-oxidation, microsomal 1-acylglycerophosphocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase in rat liver

Kawashimà, Y., Uy-Yu, N., & Kozuka, H. (1989) · Biochemical Journal · doi:10.1042/bj2610595 · Cited by 65 · see citing works

Renal excretion of perfluorooctanoic acid in male rats: Inhibitory effect of testosterone

Heuvel, J. P. V., Davis, J. W., Sommers, R., & Peterson, R. E. (1992) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.2570070107 · Cited by 65 · see citing works

A method for the determination of perfluorooctanoic acid in blood and other biological samples

Belisle, J., & Hagen, D. F. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90202-x · Cited by 65 · see citing works

Evaluation of the Male Pubertal Onset Assay to Detect Testosterone and Steroid Biosynthesis Inhibitors in CD Rats

Marty, M. S. (2001) · Toxicological Sciences · doi:10.1093/toxsci/60.2.285 · Cited by 60 · see citing works

Tissue-specific induction of 17 beta-hydroxysteroid dehydrogenase type IV by peroxisome proliferator chemicals is dependent on the peroxisome proliferator-activated receptor alpha

Fan, L., Cattley, R. C., & Corton, J. C. (1998) · Journal of Endocrinology · doi:10.1677/joe.0.1580237 · Cited by 59 · see citing works

Influence of Carbon Chain Length on the Hepatic Effects of Perfluorinated Fatty Acids. A 19F- and 31P-NMR Investigation

Goecke-Flora, C. M., & Reo, N. V. (1996) · Chemical Research in Toxicology · doi:10.1021/tx950217k · Cited by 58 · see citing works

Electrophoretic Mobility of Serum Fluoride

Taves, D. R. (1968) · Nature · doi:10.1038/220582a0 · Cited by 57 · see citing works

Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation

Keller, B., Marsman, D. S., Popp, J. A., & Thurman, R. G. (1992) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(92)90105-b · Cited by 56 · see citing works

Dermal toxicity of ammonium perfluorooctanoate

Kennedy, G. L. (1985) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(85)90172-3 · Cited by 54 · see citing works

Inhalation toxicity of ammonium perfluorooctanoate

Kennedy, G. L., Hall, G. T., Brittelli, M. R., Barnes, J. R., & Chen, H. C. (1986) · Food and Chemical Toxicology · doi:10.1016/0278-6915(86)90066-9 · Cited by 53 · see citing works

The effects of perfluoro-octanoic acid on hepatic peroxisome proliferation and related parameters show no sex-related differences in mice

Sohlenius, A., Andersson, K. K., & DePierre, J. W. (1992) · Biochemical Journal · doi:10.1042/bj2850779 · Cited by 52 · see citing works

Stimulation by Oestradiol of the Urinary Excretion of Perfluorooctanoic Acid in the Male rat

Ylinen, M., Hanhijärvi, H., Jaakonaho, J., & Peura, P. (1989) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1989.tb01172.x · Cited by 51 · see citing works

Peroxisome proliferators alter the expression of estrogen-metabolizing enzymes

Corton, J. C., Bocos, C., Moreno, E., Merritt, A., Cattley, R. C., & Gustafsson, J.-Α. (1997) · Biochimie · doi:10.1016/s0300-9084(97)81508-8 · Cited by 50 · see citing works

Lack of evidence for perfluorodecanoyl‐ or perfluorooctanoyl‐coenzyme a formation in male and female rats

Kuslikis, B. I., Heuvel, J. P. V., & Peterson, R. E. (1992) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.2570070106 · Cited by 49 · see citing works

On the mechanism of the hepatocarcinogenicity of peroxisome proliferators

Nilsson, R., Beije, B., Véronique Préat, A., Erixon, K., & Ramel, C. (1991) · Chemico-Biological Interactions · doi:10.1016/0009-2797(91)90017-2 · Cited by 48 · see citing works

DI(2-ethylhexyl)phthalate-induced changes in liver estrogen metabolism and hyperplasia

Eagon, P. K., Chandar, N., Epley, M. J., Elm, M. S., Brady, E. P., & Rao, K. N. (1994) · International Journal of Cancer · doi:10.1002/ijc.2910580519 · Cited by 48 · see citing works

Effect of Undernutrition and Amino Acid Deficiency on the Timing of Puberty in Rats

Glass, A. R., Harrison, R. M., & Swerdloff, R. S. (1976) · Pediatric Research · doi:10.1203/00006450-197611000-00009 · Cited by 47 · see citing works

Biochemical effects and zonal heterogeneity of peroxisome proliferation induced by perfluorocarboxylic acids in rat liver

Just, W. W., Gorgas, K., Hartl, F. U., Heinemann, P., Salzer, M., & Schimassek, H. (1989) · Hepatology · doi:10.1002/hep.1840090411 · Cited by 46 · see citing works

The embryo-fetal toxicity and teratogenic potential of ammonium perfluorooctanoate (APFO) in the rat.

Staples, R. E., Burgess, B. A., & Kerns, W. (1984) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(84)90200-8 · Cited by 44 · see citing works

Effects of perfluoro fatty acids on xenobiotic-metabolizing enzymes, enzymes which detoxify reactive forms of oxygen and lipid peroxidation in mouse liver

Permadi, H., Lundgren, B., Andersson, K., & DePierre, J. W. (1992) · Biochemical Pharmacology · doi:10.1016/0006-2952(92)90383-t · Cited by 43 · see citing works

Gastrointestinal and Liver Diseases

Misbah, S., Spickett, G., & Dalm, V. (2023) · doi:10.1002/9781394321803.ch14 · Cited by 43 · see citing works

Alterations by perfluorooctanoic acid of glycerolipid metabolism in rat liver

Kudo, N., Mizuguchi, H., Yamamoto, A., & Kawashima, Y. (1999) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(99)00002-2 · Cited by 42 · see citing works

Induction of peroxisomes by treatment with perfluorooctanoate does not increase rates of H2O2 production in intact liver

Handler, J. A., Seed, C. B., Bradford, B. U., & Thurman, R. G. (1992) · Toxicology Letters · doi:10.1016/0378-4274(92)90047-n · Cited by 42 · see citing works

Mechanisms for the Pancreatic Oncogenic Effects of the Peroxisome Proliferator Wyeth-14,643

Obourn, J. D., Frame, S. R., Bell, R. H., Longnecker, D. S., Elliott, G. S., & Cook, J. C. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1997.8210 · Cited by 41 · see citing works

A Proposed Species Difference in the Renal Excretion of Perfluoro Octanoic Acid in the Beagle Dog and Rat

Hanhijärvi, H., Ylinen, M., Haaranen, T., & Nevalainen, T. (1988) · Springer eBooks · doi:10.1007/978-94-009-3281-4_66 · Cited by 41 · see citing works

Peroxisome Proliferators: Species Differences in Response of Primary Hepatocyte Cultures

Elcombe, C. R., Bell, D., Elias, E., Hasmall, S. C., & Plant, N. J. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18649.x · Cited by 40 · see citing works

Exaggerated levothyroxine malabsorption due to calcium carbonate supplementation in gastrointestinal disorders

Csako, G., McGriff, N. J., Rotman-Pikielny, P., Sarlis, N. J., & Pucino, F. (2001) · Annals of Pharmacotherapy · doi:10.1345/aph.1a031 · Cited by 40 · see citing works

Evaluation of the Male Pubertal Assay's Ability to Detect Thyroid Inhibitors and Dopaminergic Agents

Marty, M. S., Crissman, J. W., & Carney, E. W. (2001) · Toxicological Sciences · doi:10.1093/toxsci/60.1.63 · Cited by 40 · see citing works

Differences in the induction of carboxylesterase isozymes in rat liver microsomes by perfluorinated fatty acids

Hosokawa, M., & Satoh, T. (1993) · Xenobiotica · doi:10.3109/00498259309059427 · Cited by 38 · see citing works

Increase in mouse liver weight following feeding of ammonium perfluorooctanoate and related fluorochemicals

Kennedy, G. L. (1987) · Toxicology Letters · doi:10.1016/0378-4274(87)90245-1 · Cited by 38 · see citing works

Lack of Peroxisome Proliferation in Marmoset Liver Following Treatment with Ciprofibrate for 3 Years

Graham, M. (1994) · Fundamental and Applied Toxicology · doi:10.1006/faat.1994.1008 · Cited by 35 · see citing works

Sex steroid metabolism and receptor status in hepatic hyperplasia and cancer in rats

Eagon, P., Elm, M., Epley, M., Shinozuka, H., & Rao, K. (1996) · Gastroenterology · doi:10.1053/gast.1996.v110.pm8613010 · Cited by 34 · see citing works

Elimination and Toxicity of Perfluorooctanoic Acid during Subchronic Administration in the Wistar Rat

Hanhijärvi, H., Ylinen, M., Kojo, A., & Kosma, V. (1987) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1987.tb01775.x · Cited by 34 · see citing works

A comparative toxicological investigation of perfluorocarboxylic acids in rats by fluorine-19 NMR spectroscopy

Goecke, C. M., Jarnot, B. M., & Reo, N. V. (1992) · Chemical Research in Toxicology · doi:10.1021/tx00028a009 · Cited by 31 · see citing works

Effect of feed restriction on Hershberger and pubertal male assay endpoints

Marty, M. S., Johnson, K. A., & Carney, E. W. (2003) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.10028 · Cited by 31 · see citing works

Induction of cellular DNA synthesis in the pancreas and kidneys of rats by peroxisome proliferators, 9-cis retinoic acid, and 3,3',5-triiodo-L-thyronine.

Ohmura, T., Katyal, S. L., Locker, J. D., Columbano, A., Columbano, A., & Shinozuka, H. (1997) · PubMed · Cited by 30 · see citing works

Hepatomegaly is an early biomarker for hepatocarcinogenesis induced by peroxisome proliferators.

Takagi, A., Sai, K., Umemura, T., Hasegawa, R., & Kurokawa, Y. (1992) · PubMed · Cited by 30 · see citing works

Toxicity and Kinetics of Perfluoro-octanoic Acid in the Wistar Rat

Kojo, A., Hanhijärvi, H., Ylinen, M., & Kosma, V. (1986) · Archives of toxicology. Supplement · doi:10.1007/978-3-642-71248-7_96 · Cited by 25 · see citing works

PERFLUOROOCTANOIC ACID INTERACTIONS WITH HUMAN SERUM ALBUMIN

Nordby, G. L., & Luck, J. M. (1956) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65805-3 · Cited by 21 · see citing works

Protein-fluoroacid interaction. Bovines serum albuminperfluoro-octanoic acid

Klevens, H. B., & Ellenbogen, E. (1954) · Discussions of the Faraday Society · doi:10.1039/df9541800277 · Cited by 21 · see citing works

Effects of prolonged administration of perfluorooctanoic acid on hepatic activities of enzymes which detoxify peroxide and xenobiotic in the rat

Kawashima, Y., Suzuki, S., Kozuka, H., Sato, M., & Suzuki, Y. (1994) · Toxicology · doi:10.1016/0300-483x(94)90070-1 · Cited by 18 · see citing works

Experimental studies on reproduction with the lipid-regulating agent gemfibrozil

Fitzgerald, J. E. (1987) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(87)90131-x · Cited by 18 · see citing works

On the role of cholecystokinin in pancreatic cancer

Herrington, M. K., & Adrian, T. E. (1995) · International Journal of Pancreatology · doi:10.1007/bf02788530 · Cited by 16 · see citing works

Inhalation Teratology and Reproduction Studies with 1,1-Dichloro-2,2,2-Trifluoroethane (HCFC-123)

Malinverno, G. (1996) · Fundamental and Applied Toxicology · doi:10.1006/faat.1996.0197 · Cited by 16 · see citing works

Perfluorocarbons: chemically inert but biologically active?

Gross, U., Rüdiger, S., & Reichelt, H. (1991) · Journal of Fluorine Chemistry · doi:10.1016/s0022-1139(00)82337-4 · Cited by 15 · see citing works

Toxicity and Teratogenicity Studies with the Hypolipidemic Drug RMI 14,514 in Rats

Gibson, J. P., Larson, E., Yarrington, J. T., Hook, R. H., KARIYA, T., & Blohm, T. R. (1981) · Toxicological Sciences · doi:10.1093/toxsci/1.1.19 · Cited by 10 · see citing works

Inhalation Teratology and Reproduction Studies with 1, 1-Dichloro-2,2,2-Trifluoroethane(HCFC-123)

Malinverno, G., Rusch, G., Millischer, R.-J., et al. (1996) · Toxicological Sciences · doi:10.1093/toxsci/34.2.276 · Cited by 10 · see citing works

On the interactions of perfluorochemical emulsions with liver microsomal membranes

Obraztsov, V. V., Kabalnov, A. S., Makarov, K. N., Gross, U., Radeck, W., & Rüdiger, S. (1993) · Journal of Fluorine Chemistry · doi:10.1016/s0022-1139(00)80401-7 · Cited by 6 · see citing works

Improper interpretation of data concerning teratogenicity: a case report.

Re, S. (1985) · PubMed · Cited by 4 · see citing works

Research and Teaching in the Field of Children's Environmental Health

Kirby, R. S., & Robson, M. G. (2004) · Journal of Children s Health · doi:10.3109/15417060490463190 · Cited by 1 · see citing works

Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings

Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620 · see citing works

Applications and societal benefits of plastics

Andrady, A. L., & Neal, M. A. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0304 · Cited by 2,464 · see citing works

Water Analysis: Emerging Contaminants and Current Issues

Richardson, S. D., & Ternes, T. A. (2014) · Analytical Chemistry · doi:10.1021/ac500508t · Cited by 2,144 · see citing works

Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and Comparisons with NHANES 1999–2000

Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247 · see citing works

Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment

Farré, M. L., Pérez, S., Kantiani, L., & Barceló, D. (2008) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2008.09.010 · Cited by 1,009 · see citing works

Perfluorinated compounds – Exposure assessment for the general population in western countries

Fromme, H., Tittlemier, S. A., Völkel, W., Wilhelm, M., & Twardella, D. (2008) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2008.04.007 · Cited by 963 · see citing works

The Developmental Toxicity of Perfluoroalkyl Acids and Their Derivatives

Lau, C., Butenhoff, J. L., & Rogers, J. M. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2003.11.031 · Cited by 867 · see citing works

Perfluorooctanoic Acid (PFOA) Exposures and Incident Cancers among Adults Living Near a Chemical Plant

Barry, V., Winquist, A. G., & Steenland, K. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1306615 · Cited by 781 · see citing works

Legacy and Emerging Perfluoroalkyl Substances Are Important Drinking Water Contaminants in the Cape Fear River Watershed of North Carolina

Sun, M., Arevalo, E., Strynar, M., Lindstrom, A., Richardson, M., Kearns, B., Pickett, A., Smith, C., & Knappe, D. R. U. (2016) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.6b00398 · Cited by 688 · see citing works

Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)

Steenland, K., Fletcher, T., & Savitz, D. A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901827 · Cited by 660 · see citing works

Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: A critical review of recent literature

Post, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639 · see citing works

Perfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort

Fei, C., McLaughlin, J. K., Tarone, R. E., & Olsen, J. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10506 · Cited by 628 · see citing works

Effects of perfluorooctanoic acid exposure during pregnancy in the mouse.

Lau, C., Thibodeaux, J. R., Hanson, R., Narotsky, M., Rogers, J. M., Lindstrom, A., & Strynar, M. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj105 · Cited by 547 · see citing works

Exposure to Polyfluoroalkyl Chemicals and Cholesterol, Body Weight, and Insulin Resistance in the General U.S. Population

Nelson, J. W., Hatch, E. E., & Webster, T. F. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901165 · Cited by 538 · see citing works

Estimating Consumer Exposure to PFOS and PFOA

Trudel, D., Horowitz, L., Wormuth, M., Scheringer, M., Cousins, I. T., & Hungerbühler, K. (2008) · Risk Analysis · doi:10.1111/j.1539-6924.2008.01017.x · Cited by 514 · see citing works

Early Life Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Latent Health Outcomes: A Review Including the Placenta as a Target Tissue and Possible Driver of Peri- and Postnatal Effects

Blake, B. E., & Fenton, S. E. (2020) · Toxicology · doi:10.1016/j.tox.2020.152565 · Cited by 499 · see citing works

Differential Activation of Nuclear Receptors by Perfluorinated Fatty Acid Analogs and Natural Fatty Acids: A Comparison of Human, Mouse, and Rat Peroxisome Proliferator-Activated Receptor-α, -β, and -γ, Liver X Receptor-β, and Retinoid X Receptor-α

Heuvel, J. P. V., Thompson, J. T., Frame, S. R., & Gillies, P. J. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl014 · Cited by 479 · see citing works

Perfluoroalkyl sulfonic and carboxylic acids: A critical review of physicochemical properties, levels and patterns in waters and wastewaters, and treatment methods

Rayne, S., & Forest, K. (2009) · Journal of Environmental Science and Health, Part A · doi:10.1080/10934520903139811 · Cited by 475 · see citing works

Exposure of Perfluorinated Chemicals through Lactation: Levels of Matched Human Milk and Serum and a Temporal Trend, 1996–2004, in Sweden

Kärrman, A., Ericson, I., van Bavel, B., Darnerud, P. O., Aune, M., Glynn, A. W., Lignell, S., & Lindström, G. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9491 · Cited by 469 · see citing works

Neonatal Exposure to Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA) Causes Neurobehavioural Defects in Adult Mice

Johansson, N., Fredriksson, A., & Eriksson, P. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2007.10.008 · Cited by 463 · see citing works

Perfluorochemicals: Potential sources of and migration from food packaging

Begley, T. H., White, K. D., Honigfort, P., Twaroski, M. L., Neches, R., & Walker, R. A. (2005) · Food Additives & Contaminants · doi:10.1080/02652030500183474 · Cited by 456 · see citing works

Serum concentrations of 11 polyfluoroalkyl compounds in the u.s. population: data from the national health and nutrition examination survey (NHANES).

Calafat, A., Kuklenyik, Z., Reidy, J., Caudill, S., Tully, J. S., & Needham, L. (2007) · Environmental Science and Technology · doi:10.1021/es062686m · Cited by 468 · see citing works

The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Human Evidence for PFOA Effects on Fetal Growth

Johnson, P. I., Sutton, P., Atchley, D. S., Koustas, E., Lam, J., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307893 · Cited by 449 · see citing works

PFAS and cancer, a scoping review of the epidemiologic evidence

Steenland, K., & Winquist, A. G. (2020) · Environmental Research · doi:10.1016/j.envres.2020.110690 · Cited by 431 · see citing works

The Navigation Guide Systematic Review Methodology: A Rigorous and Transparent Method for Translating Environmental Health Science into Better Health Outcomes

Woodruff, T. J., & Sutton, P. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307175 · Cited by 427 · see citing works

Emerging endocrine disrupters: perfluoroalkylated substances

Jensen, A. A., & Leffers, H. C. B. (2008) · International Journal of Andrology · doi:10.1111/j.1365-2605.2008.00870.x · Cited by 423 · see citing works

Tracking the Pathways of Human Exposure to Perfluorocarboxylates

Vestergren, R., & Cousins, I. T. (2009) · Environmental Science & Technology · doi:10.1021/es900228k · Cited by 419 · see citing works

Characterisation of human exposure pathways to perfluorinated compounds — Comparing exposure estimates with biomarkers of exposure

Haug, L. S., Huber, S., Becher, G., & Thomsen, C. (2011) · Environment International · doi:10.1016/j.envint.2011.01.011 · Cited by 417 · see citing works

Activation of Mouse and Human Peroxisome Proliferator-Activated Receptors (α, β/δ, γ) by Perfluorooctanoic Acid and Perfluorooctane Sulfonate

Takacs, M. L., & Abbott, B. D. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfl135 · Cited by 396 · see citing works

Maternal levels of perfluorinated chemicals and subfecundity

Fei, C., McLaughlin, J. K., Lipworth, L., & Olsen, J. (2009) · Human Reproduction · doi:10.1093/humrep/den490 · Cited by 385 · see citing works

Legacy and Emerging Per- and Polyfluoroalkyl Substances: Analytical Techniques, Environmental Fate, and Health Effects

Brase, R. A., Mullin, E. J., & Spink, D. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22030995 · Cited by 374 · see citing works

Association of Perfluorooctanoic Acid and Perfluorooctane Sulfonate With Serum Lipids Among Adults Living Near a Chemical Plant

Steenland, K., Tinker, S., Frisbee, S. J., DUCATMAN, A. M., & Vaccarino, V. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp279 · Cited by 374 · see citing works

Studies on the Toxicological Effects of PFOA and PFOS on Rats Using Histological Observation and Chemical Analysis

Cui, L., Zhou, Q.-F., Liao, C.-Y., Fu, J.-J., & Jiang, G.-B. (2009) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-008-9194-6 · Cited by 368 · see citing works

Water Analysis: Emerging Contaminants and Current Issues

Richardson, S. D., & Ternes, T. A. (2005) · Analytical Chemistry · doi:10.1021/ac058022x · Cited by 363 · see citing works

The C8 Health Project: Design, Methods, and Participants

Frisbee, S. J., Brooks, A. P., Maher, A., Flensborg, P., Arnold, S., Fletcher, T., Steenland, K., Shankar, A., Knox, S. S., Pollard, C. R., et al. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800379 · Cited by 363 · see citing works

Biomonitoring of Perfluorinated Compounds in Children and Adults Exposed to Perfluorooctanoate-Contaminated Drinking Water

Hölzer, J., Midasch, O., Rauchfuss, K., Kraft, M., Reupert, R., Angerer, J., Kleeschulte, P., Marschall, N., & Wilhelm, M. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11064 · Cited by 356 · see citing works

Multiple pathways of human exposure to poly- and perfluoroalkyl substances (PFASs): From external exposure to human blood

Poothong, S., Papadopoulou, E., Padilla-Sánchez, J. A., Thomsen, C., & Haug, L. S. (2020) · Environment International · doi:10.1016/j.envint.2019.105244 · Cited by 357 · see citing works

Community Exposure to Perfluorooctanoate: Relationships Between Serum Concentrations and Exposure Sources

Emmett, E. A., Shofer, F. S., Zhang, H., Freeman, D. W., Desai, C. S., & Shaw, L. M. J. (2006) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000232486.07658.74 · Cited by 357 · see citing works

The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Nonhuman Evidence for PFOA Effects on Fetal Growth

Koustas, E., Lam, J., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307177 · Cited by 349 · see citing works

Perfluorinated compounds affect the function of sex hormone receptors

Kjeldsen, L. S., & Bonefeld‐Jørgensen, E. C. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-013-1753-3 · Cited by 345 · see citing works

Perfluorinated Compounds in Tap Water from China and Several Other Countries

Mak, Y. L., Taniyasu, S., Yeung, L. W. Y., Lu, G.-H., Jin, L. N., Yang, Y., Lam, P. K. S., Kannan, K., & Yamashita, N. (2009) · Environmental Science & Technology · doi:10.1021/es900637a · Cited by 337 · see citing works

Pre- and Postnatal Exposure to Perfluorinated Compounds (PFCs)

Fromme, H., Mosch, C., Morovitz, M., Alba‐Alejandre, I., Boehmer, S., Kiranoglu, M., Faber, F. L., Hannibal, I., Genzel‐Boroviczény, O., Koletzko, B. V., et al. (2010) · Environmental Science & Technology · doi:10.1021/es101184f · Cited by 332 · see citing works

Perfluoroalkyl substances (PFAS) and their effects on the placenta, pregnancy, and child development: a potential mechanistic role for placental peroxisome proliferator-activated receptors (PPARs)

Szilagyi, J. T., Avula, V., & Fry, R. C. (2020) · Current Environmental Health Reports · doi:10.1007/s40572-020-00279-0 · Cited by 328 · see citing works

Short- and long-chain perfluoroalkyl substances in the water, suspended particulate matter, and surface sediment of a turbid river

Zhao, P., Xia, X., Dong, J., Xia, N., Jiang, X., Li, Y., & Zhu, Y. (2016) · Science of The Total Environment · doi:10.1016/j.scitotenv.2016.05.221 · Cited by 322 · see citing works

Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action

Andersen, M. E., Butenhoff, J. L., Chang, S., Farrar, D. G., Kennedy, G. L., Lau, C. S., Olsen, G. W., Seed, J. G., & Wallace, K. B. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm270 · Cited by 322 · see citing works

Historical Comparison of Perfluorooctanesulfonate, Perfluorooctanoate, and Other Fluorochemicals in Human Blood

Olsen, G. W., Huang, H.-Y., Helzlsouer, K. J., Hansen, K. J., Butenhoff, J. L., & Mandel, J. H. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7544 · Cited by 318 · see citing works

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)

Ehrlich, V. A., Bil, W., Vandebriel, R. J., Granum, B. B., Luijten, M., Lindeman, B., Grandjean, P., Kaiser, A.-M., Hauzenberger, I., Hartmann, C., et al. (2023) · Environmental Health · doi:10.1186/s12940-022-00958-5 · Cited by 315 · see citing works

Occurrence of Perfluoroalkyl Surfactants in Water, Fish, and Birds from New York State

Sinclair, E., Mayack, D. T., Roblee, K. J., Yamashita, N., & Kannan, K. (2006) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-005-1188-z · Cited by 315 · see citing works

Perfluoroalkyl and polyfluoroalkyl substances and human fetal growth: A systematic review

Bach, C., Bech, B., Brix, N., Nøhr, E., Bonde, J. P. E., & Henriksen, T. (2015) · Critical Reviews in Toxicology · doi:10.3109/10408444.2014.952400 · Cited by 282 · see citing works

Assessment of lipid, hepatic, and thyroid parameters with serum perfluorooctanoate (PFOA) concentrations in fluorochemical production workers

Olsen, G. W., & Zobel, L. R. (2007) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-007-0213-0 · Cited by 301 · see citing works

Per- and polyfluorinated substances (PFASs): Environmental challenges

Krafft, M. P., & Riess, J. G. (2015) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2015.07.004 · Cited by 294 · see citing works

Correlations between Prenatal Exposure to Perfluorinated Chemicals and Reduced Fetal Growth

Washino, N., Saijo, Y., Sasaki, S., Kato, S., Ban, S., Konishi, K., Ito, R., Nakata, A., Iwasaki, Y., Saito, K., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11681 · Cited by 299 · see citing works

Suppression of Humoral Immunity in Mice following Exposure to Perfluorooctane Sulfonate

Peden‐Adams, M. M., Keller, J. M., EUDALY, J. G., Berger, J., Gilkeson, G. S., & Keil, D. E. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfn059 · Cited by 278 · see citing works

Perfluorooctanoic Acid, Perfluorooctanesulfonate, and Serum Lipids in Children and Adolescents: Results From the C8 Health Project

Frisbee, S. J., Shankar, A., Knox, S. S., Steenland, K., Savitz, D. A., Fletcher, T., & Ducatman, A. M. (2010) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpediatrics.2010.163 · Cited by 274 · see citing works

Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community

Worley, R. R., Moore, S. M., Tierney, B. C., Ye, X., Calafat, A. M., Campbell, S., Woudneh, M. B., & Fisher, J. (2017) · Environment International · doi:10.1016/j.envint.2017.06.007 · Cited by 272 · see citing works

Immunotoxicity of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and the Role of Peroxisome Proliferator-Activated Receptor Alpha

DeWitt, J., Shnyra, A., Badr, M., Loveless, S., Hoban, D., Frame, S., Cunard, R., Anderson, S., Meade, B., Peden-Adams, M., et al. (2009) · Critical Reviews in Toxicology · doi:10.1080/10408440802209804 · Cited by 272 · see citing works

Association Among Serum Perfluoroalkyl Chemicals, Glucose Homeostasis, and Metabolic Syndrome in Adolescents and Adults

Lin, C., Chen, P., Lin, Y.-C., & Lin, L. (2008) · Diabetes Care · doi:10.2337/dc08-1816 · Cited by 262 · see citing works

Perfluorooctanoic Acid Induced Developmental Toxicity in the Mouse is Dependent on Expression of Peroxisome Proliferator Activated Receptor-alpha

Abbott, B. D., Wolf, C. J., Schmid, J., Das, K. P., ZEHR, R. D. J., Helfant, L., Nakayama, S. F., Lindstrom, A. B., Strynar, M. J., & Lau, C. S. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm110 · Cited by 262 · see citing works

Production of Perfluorinated Carboxylic Acids (PFCAs) from the Biotransformation of Polyfluoroalkyl Phosphate Surfactants (PAPS): Exploring Routes of Human Contamination

D’eon, J. C., & Mabury, S. A. (2007) · Environmental Science & Technology · doi:10.1021/es070126x · Cited by 259 · see citing works

Riverine Discharge of Perfluorinated Carboxylates from the European Continent

McLachlan, M. S., Holmström, K. E., Reth, M., & Berger, U. (2007) · Environmental Science & Technology · doi:10.1021/es071471p · Cited by 258 · see citing works

Serum Biomarkers of Exposure to Perfluoroalkyl Substances in Relation to Serum Testosterone and Measures of Thyroid Function among Adults and Adolescents from NHANES 2011–2012

Lewis, R. C., Johns, L. E., & Meeker, J. D. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph120606098 · Cited by 254 · see citing works

Modeling Global-Scale Fate and Transport of Perfluorooctanoate Emitted from Direct Sources

Armitage, J. M., Cousins, I. T., Buck, R. C., Prevedouros, K., Russell, M. H., MacLeod, M., & Korzeniowski, S. H. (2006) · Environmental Science & Technology · doi:10.1021/es0614870 · Cited by 253 · see citing works

Perfluoroalkyl compounds in Danish wastewater treatment plants and aquatic environments

Bossi, R., Strand, J., Sortkjær, O., & Larsen, M. M. (2007) · Environment International · doi:10.1016/j.envint.2007.10.002 · Cited by 253 · see citing works

Adsorption of perfluorooctanoic acid and perfluorooctanesulfonic acid to iron oxide surfaces as studied by flow-through ATR-FTIR spectroscopy

Gao, X., & Chorover, J. (2012) · Environmental Chemistry · doi:10.1071/en11119 · Cited by 251 · see citing works

Renal elimination of perfluorocarboxylates (PFCAs)

Han, X., Nabb, D. L., Russell, M. H., Kennedy, G. L., & Rickard, R. W. (2012) · Chemical Research in Toxicology · doi:10.1021/tx200363w · Cited by 250 · see citing works

Toxicogenomic Study of Triazole Fungicides and Perfluoroalkyl Acids in Rat Livers Predicts Toxicity and Categorizes Chemicals Based on Mechanisms of Toxicity

Martin, M. T., Brennan, R., Hu, W., Ayanoĝlu, E., Lau, C. S., Ren, H., Wood, C. R., Corton, J. C., Kavlock, R. J., & Dix, D. J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm065 · Cited by 249 · see citing works

Estrogen-Like Activity of Perfluoroalkyl Acids In Vivo and Interaction with Human and Rainbow Trout Estrogen Receptors In Vitro

Benninghoff, A. D., Bisson, W. H., Koch, D. C., Ehresman, D. J., Kolluri, S. K., & Williams, D. E. (2010) · Toxicological Sciences · doi:10.1093/toxsci/kfq379 · Cited by 248 · see citing works

Significant Residual Fluorinated Alcohols Present in Various Fluorinated Materials

Dinglasan-Panlilio, M. J. A., & Mabury, S. A. (2006) · Environmental Science & Technology · doi:10.1021/es051619+ · Cited by 243 · see citing works

Physicochemical properties and aquatic toxicity of poly- and Perfluorinated compounds

Ding, G., & Peijnenburg, W. J. G. M. (2013) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643389.2011.627016 · Cited by 241 · see citing works

Thirty years of medical surveillance in perfluooctanoic acid production workers

Costa, G., Sartori, S., & Consonni, D. (2009) · Journal of Occupational & Environmental Medicine · doi:10.1097/jom.0b013e3181965d80 · Cited by 238 · see citing works

Activation of Human Nuclear Receptors by Perfluoroalkylated Substances (PFAS)

Behr, A.-C., Plinsch, C., Braeuning, A., & Buhrke, T. (2020) · Toxicology in Vitro · doi:10.1016/j.tiv.2019.104700 · Cited by 235 · see citing works

Gene Expression Profiles in Rat Liver Treated With Perfluorooctanoic Acid (PFOA)

Guruge, K. S., Yeung, L. W. Y., Yamanaka, N., Miyazaki, S., Lam, P. K. S., Giesy, J. P., Jones, P. D., & Yamashita, N. (2005) · Toxicological Sciences · doi:10.1093/toxsci/kfj011 · Cited by 232 · see citing works

Water Analysis:  Emerging Contaminants and Current Issues

Richardson, S. D. (2007) · Analytical Chemistry · doi:10.1021/ac070719q · Cited by 233 · see citing works

Determination of perfluorooctanoic acid and perfluorooctanesulfonate in human tissues by liquid chromatography/single quadrupole mass spectrometry

Maestri, L., Negri, S., Ferrari, M., GHITTORI, S., Fabris, F., Danesino, P., & Imbriani, M. (2006) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.2661 · Cited by 225 · see citing works

Placental transfer of perfluorinated compounds is selective – A Norwegian Mother and Child sub-cohort study

Gützkow, K. B., Haug, L. S., Thomsen, C., Sabaredzovic, A., Becher, G., & Brunborg, G. (2011) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2011.08.011 · Cited by 225 · see citing works

Determinants of Fetal Exposure to Polyfluoroalkyl Compounds in Baltimore, Maryland

Apelberg, B. J., Goldman, L. R., Calafat, A. M., Herbstman, J. B., Kuklenyik, Z., Heidler, J., Needham, L. L., Halden, R. U., & Witter, F. R. (2007) · Environmental Science & Technology · doi:10.1021/es0700911 · Cited by 221 · see citing works

Review of the expression of peroxisome proliferator-activated receptors alpha (PPARα), beta (PPARβ), and gamma (PPARγ) in rodent and human development

Abbott, B. D. (2008) · Reproductive Toxicology · doi:10.1016/j.reprotox.2008.10.001 · Cited by 218 · see citing works

Is Fish a Major Source of Fluorinated Surfactants and Repellents in Humans Living on the Baltic Coast?

Falandysz, J., Taniyasu, S., Gulkowska, A., Yamashita, N., & Schulte‐Oehlmann, U. (2006) · Environmental Science & Technology · doi:10.1021/es051799n · Cited by 219 · see citing works

The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Integration of Animal and Human Evidence for PFOA Effects on Fetal Growth

Lam, J., Koustas, E., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307923 · Cited by 214 · see citing works

Perfluorinated compounds are related to breast cancer risk in greenlandic inuit: A case control study

Bonefeld‐Jørgensen, E. C., Long, M., Bossi, R., Ayotte, P., Asmund, G., Krüger, T., Ghisari, M., Mulvad, G., Kern, P., Nzulumiki, P., et al. (2011) · Environmental Health · doi:10.1186/1476-069x-10-88 · Cited by 216 · see citing works

A modeling assessment of the physicochemical properties and environmental fate of emerging and novel per- and polyfluoroalkyl substances

Gomis, M. I., Wang, Z., Scheringer, M., & Cousins, I. T. (2015) · Science of The Total Environment · doi:10.1016/j.scitotenv.2014.10.062 · Cited by 211 · see citing works

Interspecies differences in perfluoroalkyl substances (PFAS) toxicokinetics and application to health-based criteria

Pizzurro, D. M., Seeley, M., Kerper, L. E., & Beck, B. D. (2019) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2019.05.008 · Cited by 206 · see citing works

Perfluorinated compounds: Emerging POPs with potential immunotoxicity

Corsini, E., Luebke, R. W., Germolec, D. R., & DeWitt, J. C. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.01.038 · Cited by 207 · see citing works

Neurotoxic Effects of Perfluoroalkylated Compounds: Mechanisms of Action and Environmental Relevance

Mariussen, E. (2012) · Archives of Toxicology · doi:10.1007/s00204-012-0822-6 · Cited by 204 · see citing works

Enhanced Adsorption of PFOA and PFOS on Multiwalled Carbon Nanotubes under Electrochemical Assistance

Li, X., Chen, S., Quan, X., & Zhang, Y. (2011) · Environmental Science & Technology · doi:10.1021/es202026v · Cited by 201 · see citing works

Toxicogenomic Dissection of the Perfluorooctanoic Acid Transcript Profile in Mouse Liver: Evidence for the Involvement of Nuclear Receptors PPARα and CAR

Rosen, M. B., Lee, J. S., Ren, H., Vallanat, B., Liu, J., Waalkes, M. P., Abbott, B. D., Lau, C. S., & Corton, J. C. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfn025 · Cited by 200 · see citing works

Perfluorinated Compounds in River Water, River Sediment, Market Fish, and Wildlife Samples from Japan

Senthilkumar, K. K., Ohi, E., Sajwan, K., Takasuga, T., & Kannan, K. (2007) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/s00128-007-9243-2 · Cited by 199 · see citing works

Removal of PFOS, PFOA and other perfluoroalkyl acids at water reclamation plants in South East Queensland Australia

Thompson, J., Eaglesham, G., Reungoat, J., Poussade, Y., Bartkow, M., Lawrence, M., & Mueller, J. F. (2011) · Chemosphere · doi:10.1016/j.chemosphere.2010.10.040 · Cited by 198 · see citing works

Environmental Fate and Transport Modeling for Perfluorooctanoic Acid Emitted from the Washington Works Facility in West Virginia

Shin, H.-M., Vieira, V. M., Ryan, P. B., Detwiler, R., Sanders, B., Steenland, K., & Bartell, S. M. (2011) · Environmental Science & Technology · doi:10.1021/es102769t · Cited by 198 · see citing works

Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates

Yang, C.-H., Glover, K. P., & Han, X. (2010) · Toxicological Sciences · doi:10.1093/toxsci/kfq219 · Cited by 197 · see citing works

Community Exposure to Perfluorooctanoate: Relationships Between Serum Levels and Certain Health Parameters

Emmett, E. A., Zhang, H., Shofer, F. S., Freeman, D. W., Rodway, N. V., Desai, C. S., & Shaw, L. M. J. (2006) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000233380.13087.37 · Cited by 197 · see citing works

Estimating the contribution of precursor compounds in consumer exposure to PFOS and PFOA

Vestergren, R., Cousins, I. T., Trudel, D., Wormuth, M., & Scheringer, M. (2008) · Chemosphere · doi:10.1016/j.chemosphere.2008.08.011 · Cited by 194 · see citing works

Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells

Eriksen, K. T., Raaschou‐Nielsen, O., Sørensen, M., Roursgaard, M., Loft, S. H., & Möller, P. (2010) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2010.04.024 · Cited by 192 · see citing works

Analysis of perfluorooctanoate (PFOA) and other perfluorinated compounds (PFCs) in the River Po watershed in N-Italy

Loos, R., Giovanni, L., Huber, T., Wollgast, J., Christoph, E. H., de Jager, A., Gawlik, B. M., Hanke, G., Umlauf, G., & Zaldı́var, J. M. (2007) · Chemosphere · doi:10.1016/j.chemosphere.2007.09.022 · Cited by 193 · see citing works

Investigating the biodegradability of perfluorooctanoic acid

Liou, J. S.-C., Szostek, B., DeRito, C. M., & Madsen, E. L. (2010) · Chemosphere · doi:10.1016/j.chemosphere.2010.03.009 · Cited by 191 · see citing works

Cross-Sectional Study of Lipids and Liver Enzymes Related to a Serum Biomarker of Exposure (ammonium perfluorooctanoate or APFO) as Part of a General Health Survey in a Cohort of Occupationally Exposed Workers

Sakr, C. J., Kreckmann, K. H., Green, J. W., Gillies, P. J., Reynolds, J. L., & Leonard, R. C. (2007) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e318156eca3 · Cited by 191 · see citing works

Perfluorinated chemicals in relation to other persistent organic pollutants in human blood

Kärrman, A., van Bavel, B., Järnberg, U., Hardell, L., & Lindström, G. (2006) · Chemosphere · doi:10.1016/j.chemosphere.2005.11.040 · Cited by 191 · see citing works

Longitudinal Study of Serum Lipids and Liver Enzymes in Workers With Occupational Exposure to Ammonium Perfluorooctanoate

Sakr, C. J., Leonard, R. C., Kreckmann, K. H., Slade, M. D., & Cullen, M. R. (2007) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e318124a93f · Cited by 189 · see citing works

The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat

Butenhoff, J. L., Kennedy, G. L., Frame, S. R., O’Connor, J. C., & York, R. G. (2004) · Toxicology · doi:10.1016/j.tox.2003.11.005 · Cited by 188 · see citing works

Levels of 12 Perfluorinated Chemicals in Pooled Australian Serum, Collected 2002−2003, in Relation to Age, Gender, and Region

Kärrman, A., Mueller, J. F., van Bavel, B., Harden, F. A., Toms, L.-M. L., & Lindström, G. (2006) · Environmental Science & Technology · doi:10.1021/es060301u · Cited by 188 · see citing works

Mode of Action analysis of perfluorooctanoic acid (PFOA) tumorigenicity and Human Relevance

Klaunig, J. E., Hocevar, B. A., & Kamendulis, L. M. (2011) · Reproductive Toxicology · doi:10.1016/j.reprotox.2011.10.014 · Cited by 99 · see citing works

Perfluorooctanoic Acid (PFOA)–induced Liver Lesions in Two Strains of Mice Following Developmental Exposures: PPARa Is Not Required

Filgo, A. J., Quist, E. M., Hoenerhoff, M. J., Brix, A. E., Kissling, G. E., Suzanne, & Fenton, E. (2016)

Advance Access publication February 14, 2008 Toxicogenomic Dissection of the Perfluorooctanoic Acid Transcript Profile in Mouse Liver: Evidence for the Involvement of Nuclear

Ppara, R. (2007)

Perfluorooctanoic acid (PFOA)-induced liver lesions in two strains of mice following developmental exposures: PPARa is not required. Manuscript submitted for publication in Toxicological Pathology

Filgo, A. J., Quist, E. M., Hoenerhoff, M. J., Brix, A. E., Kissling, G. E., Suzanne, & Fenton, E. (2014)

Evaluating the mode of action of perfluorooctanoic acid-induced liver tumors in male Sprague-Dawley rats using a toxicogenomic approach

Li, X., Wang, Z., Wu, Q., & Klaunig, J. E. (2024) · Journal of Environmental Science and Health Part C · doi:10.1080/26896583.2024.2327969 · Cited by 3 · see citing works