The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Toxic Impact of Bromide and Iodide on Drinking Water Disinfected with Chlorine or Chloramines
Abstract
Disinfectants inactivate pathogens in source water; however, they also react with organic matter and bromide/iodide to form disinfection byproducts (DBPs). Although only a few DBP classes have been systematically analyzed for toxicity, iodinated and brominated DBPs tend to be the most toxic. The objectives of this research were (1) to determine if monochloramine (NH2Cl) disinfection generated drinking water with less toxicity than water disinfected with free chlorine (HOCl) and (2) to determine the impact of added bromide and iodide in conjunction with HOCl or NH2Cl disinfection on mammalian cell cytotoxicity and genomic DNA damage induction. Water disinfected with chlorine was less cytotoxic but more genotoxic than water disinfected with chloramine. For both disinfectants, the addition of Br(-) and I(-) increased cytotoxicity and genotoxicity with a greater response observed with NH2Cl disinfection. Both cytotoxicity and genotoxicity were highly correlated with TOBr and TOI. However, toxicity was weakly and inversely correlated with TOCl. Thus, the forcing agents for cytotoxicity and genotoxicity were the generation of brominated and iodinated DBPs rather than the formation of chlorinated DBPs. Disinfection practices need careful consideration especially when using source waters containing elevated bromide and iodide.
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RICHARDSON, S., PLEWA, M., WAGNER, E., SCHOENY, R., & DEMARINI, D. (2007) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2007.09.001 · Cited by 3,317
Self-citationOccurrence of a new generation of disinfection byproducts†
Krasner, S. W., Weinberg, H. S., Richardson, S. D., Pastor, S. J., Chinn, R., Sclimenti, M. J., Onstad, G. D., & Thruston, A. D. (2006) · Environmental Science & Technology · doi:10.1021/es060353j · Cited by 1,633
Haloacetonitriles vs. Regulated Haloacetic Acids: Are Nitrogen-Containing DBPs More Toxic?
Muellner, M. G., Wagner, E. D., McCalla, K., Richardson, S. D., Woo, Y.-T., & Plewa, M. J. (2007) · Environmental Science & Technology · doi:10.1021/es0617441 · Cited by 751
Self-citationOccurrence and Mammalian Cell Toxicity of Iodinated Disinfection Byproducts in Drinking Water
Richardson, S. D., Fasano, F., Ellington, J. J., Crumley, F. G., Buettner, K. M., Evans, J. J., Blount, B. C., Silva, L. K., Waite, T. J., Luther, G. W., et al. (2008) · Environmental Science & Technology · doi:10.1021/es801169k · Cited by 655
Self-citationCostet, N., Villanueva, C. M., Jaakkola, J. J. K., Kogevinas, M., Cantor, K. P., King, W. D., Lynch, C. F., Nieuwenhuijsen, M. J., & Cordier, S. (2011) · Occupational and Environmental Medicine · doi:10.1136/oem.2010.062703 · Cited by 231
Exposure to Drinking Water Disinfection By-Products and Pregnancy Loss
Savitz, D. A., Singer, P. C., Herring, A. H., Hartmann, K. E., Weinberg, H. S., & Makarushka, C. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj300 · Cited by 177
The epidemiology and possible mechanisms of disinfection by-products in drinking water
Nieuwenhuijsen, M. J., Grellier, J., Smith, R., Iszatt, N., Bennett, J., Best, N., & Toledano, M. (2009) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2009.0116 · Cited by 153
Costet, N., Garlantézec, R., Monfort, C., Rouget, F., Gagnière, B., Chevrier, C., & Cordier, S. (2012) · American Journal of Epidemiology · doi:10.1093/aje/kwr419 · Cited by 95
Drinking Water Disinfection By-Product Exposure and Fetal Growth
Hoffman, C. S., Mendola, P., Savitz, D. A., Herring, A. H., Loomis, D., Hartmann, K. E., Singer, P. C., Weinberg, H. S., & Olshan, A. F. (2008) · Epidemiology · doi:10.1097/ede.0b013e3181812bd4 · Cited by 85
Maternal Exposure to Drinking-water Chlorination By-products and Small-for-gestational-age Neonates
Levallois, P., Gingras, S., Marcoux, S., Legay, C., Catto, C., Rodriguez, M., & Tardif, R. (2012) · Epidemiology · doi:10.1097/ede.0b013e3182468569 · Cited by 69
Cited by
Li, X.-F., & Mitch, W. A. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.7b05440 · Cited by 1,020
Jiang, J., Han, J., & Zhang, X. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.9b06403 · Cited by 284
Metadata
- Authors
- Yang, Y., Komaki, Y., Kimura, S. Y., Hu, H.-Y., Wagner, E. D., Mariñas, B. J., & Plewa, M. J.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-10-07
- Volume
- 48
- Issue
- 20
- Pages
- 12362-12369
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2325482026
- Cited by
- 288
- References
- 10
- FWCI
- 10.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yang, Y., Komaki, Y., Kimura, S. Y., Hu, H.-Y., Wagner, E. D., Mariñas, B. J., & Plewa, M. J. (2014). Toxic Impact of Bromide and Iodide on Drinking Water Disinfected with Chlorine or Chloramines. Environmental Science & Technology. https://doi.org/10.1021/es503621e
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