The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Biomedical Applications of Metal Organic Frameworks
Abstract
We have witnessed a rapid growth in the field of a new nanoporous material group, metal organic frameworks (MOFs), over the past decade. MOFs possess a wide array of potential applications in chemical engineering, chemistry, and materials science, including gas storage, gas separation, and catalysis. One of the areas MOFs started to appear recently is biomedical applications. The unique physical and chemical characteristics of MOFs make them promising candidates for drug storage and drug delivery, nitric oxide storage and delivery, imaging, and sensing. In this review, we outline the recent progress of using MOFs as a promising platform in biomedical applications due to their high drug loading capacity, biodegradability, and versatile functionality. We also demonstrate the potential of MOFs for continuous development and implementation in biomedical applications by discussing issues including stability, toxicology, and biocompatibility. Although significant progress has been made in utilizing MOFs for biomedical applications, further improvements must still occur before MOFs can become viable therapeutics options.
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Cites
Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications
McKinlay, A. C., Morris, R. E., Horcajada, P., Férey, G., Gref, R., Couvreur, P., & Serre, C. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201000048 · Cited by 1,256
Cited by
Zhuang, J., Kuo, C.-H., Chou, L.-Y., Liu, D.-Y., Weerapana, E., & Tsung, C.-K. (2014) · ACS Nano · doi:10.1021/nn406590q · Cited by 873
MOF positioning technology and device fabrication
Falcaro, P., Ricco, R., Doherty, C. M., Liang, K., Hill, A. J., & Styles, M. J. (2014) · Chem. Soc. Rev. · doi:10.1039/c4cs00089g · Cited by 710
Advanced Porous Materials in Mixed Matrix Membranes
Cheng, Y., Ying, Y., Japip, S., Jiang, S., Chung, T., Zhang, S., & Zhao, D. (2018) · Advanced Materials · doi:10.1002/adma.201802401 · Cited by 448
Li, D., Yadav, A., Zhou, H., Roy, K., Thanasekaran, P., & Lee, C. (2024) · Global Challenges · doi:10.1002/gch2.202300244 · Cited by 437
Selective Adsorption of Sulfur Dioxide in a Robust Metal–Organic Framework Material
Savage, M., Cheng, Y., Easun, T. L., Eyley, J. E., Argent, S. P., Warren, M. R., Lewis, W., Murray, C., Tang, C. C., Frogley, M. D., et al. (2016) · Advanced Materials · doi:10.1002/adma.201602338 · Cited by 267
Metadata
- Authors
- Keskin, S., & Kızılel, S.
- Venue
- Industrial & Engineering Chemistry Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-01-18
- Volume
- 50
- Issue
- 4
- Pages
- 1799-1812
- ISSN
- 0888-5885 (ISSN-L)
- 1520-5045
- OpenAlex
- W2322498174
- Cited by
- 607
- References
- 2
- FWCI
- 18.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- Keskin, S., & Kızılel, S. (2011). Biomedical Applications of Metal Organic Frameworks. Industrial & Engineering Chemistry Research. https://doi.org/10.1021/ie101312k
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