The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Solvent-Resistant Photocurable “Liquid Teflon” for Microfluidic Device Fabrication
Abstract
We report the first fabrication of a solvent-compatible microfluidic device based on photocurable "Liquid Teflon" materials. The materials are highly fluorinated functionalized perfluoropolyethers (PFPEs) that have liquidlike viscosities that can be cured into tough, highly durable elastomers that exhibit the remarkable chemical resistance of fluoropolymers such as Teflon. Poly(dimethylsiloxane) (PDMS) elastomers have rapidly become the material of choice for many recent microfluidic device applications. Despite the advantages of PDMS in relation to microfluidics technology, the material suffers from a serious drawback in that it swells in most organic solvents. The swelling of PDMS-based devices in organic solvents greatly disrupts the micrometer-sized features and makes it impossible for fluids to flow inside the channels. Our approach to this problem has been to replace PDMS with photocurable perfluoropolyethers. Device fabrication and valve actuation were accomplished using established procedures for PDMS devices. The additional advantage of photocuring allows fabrication time to be decreased from several hours to a matter of minutes. The PFPE-based device exhibited mechanical properties similar to those of Sylgard 184 before and after curing as well as remarkable resistance to organic solvents. This work has the potential to expand the field of microfluidics to many novel applications.
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Rubinstein, M., & Colby, R. H. (2003) · doi:10.1093/oso/9780198520597.001.0001 · Cited by 5,686
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Unger, M. A., Chou, H.-P., Thorsen, T., Scherer, A., & Quake, S. R. (2000) · Science · doi:10.1126/science.288.5463.113 · Cited by 4,010
Self-citationPoly(dimethylsiloxane) as a Material for Fabricating Microfluidic Devices
McDonald, J. C., & Whitesides, G. M. (2002) · Accounts of Chemical Research · doi:10.1021/ar010110q · Cited by 2,454
Microfluidic Large-Scale Integration
Thorsen, T., Maerkl, S. J., & Quake, S. R. (2002) · Science · doi:10.1126/science.1076996 · Cited by 2,222
Self-citationSelf-Assembly of Highly Phosphorylated Silaffins and Their Function in Biosilica Morphogenesis
Kröger, N., Lorenz, S., Brunner, E., & Sumper, M. (2002) · Science · doi:10.1126/science.1076221 · Cited by 792
Chain Mobility in the Amorphous Region of Nylon 6 Observed under Active Uniaxial Deformation
Loo, L. S., Cohen, R. E., & Gleason, K. K. (2000) · Science · doi:10.1126/science.288.5463.116 · Cited by 229
Perfluoropolyether Synthesis in Liquid Carbon Dioxide by Hexafluoropropylene Photooxidation
Bunyard, W. C., Romack, T. J., & DeSimone, J. M. (1999) · Macromolecules · doi:10.1021/ma981588l · Cited by 28
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Self-citationThe past, present and potential for microfluidic reactor technology in chemical synthesis
Elvira, K. S., i Solvas, X. C., Wootton, R. C. R., & deMello, A. J. (2013) · Nature Chemistry · doi:10.1038/nchem.1753 · Cited by 1,203
Greener Approaches to Organic Synthesis Using Microreactor Technology
Mason, B. P., Price, K. E., Steinbacher, J. L., Bogdan, A. R., & McQuade, D. T. (2007) · Chemical Reviews · doi:10.1021/cr050944c · Cited by 985
Advances in Microfluidic Materials, Functions, Integration, and Applications
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Metadata
- Authors
- Rolland, J. P., Van Dam, R. M., Schorzman, D. A., Quake, S. R., & DeSimone, J. M.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-02-06
- Volume
- 126
- Issue
- 8
- Pages
- 2322-2323
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1966062221
- Cited by
- 440
- References
- 7
- FWCI
- 16.91
- Type
- journal article
- Language
- en
- Open access
- closed
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