The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Control of Protein Structure and Function through Surface Recognition by Tailored Nanoparticle Scaffolds
Abstract
Thioalkyl and thioalkylated oligo(ethylene glycol) (OEG) ligands with chain-end functionality were used to fabricate water-soluble CdSe nanoparticle scaffolds. Surface recognition of chymotrypsin (ChT) was achieved using these functionalized nanoparticle scaffolds, with three levels of interaction demonstrated: no interaction (OEG terminated with hydroxyl group), inhibition with denaturation (carboxylate-terminated thioalkyl ligands), and inhibition with retention of structure (carboxylate-terminated OEG). The latter process was reversible upon an increase in ionic strength, with essentially complete restoration of enzymatic activity.
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Citations
Cites
Anatomy of hot spots in protein interfaces
Bogan, A. A., & Thorn, K. S. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.1843 · Cited by 1,988
Cited by
Walkey, C. D., & Chan, W. C. W. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15233e · Cited by 1,758
Applications of Nanoparticles in Biology
De, M., Ghosh, P. S., & Rotello, V. M. (2008) · Advanced Materials · doi:10.1002/adma.200703183 · Cited by 1,547
Self-citationGold nanoparticles: opportunities and challenges in nanomedicine
Arvizo, R., Bhattacharya, R., & Mukherjee, P. (2010) · Expert Opinion on Drug Delivery · doi:10.1517/17425241003777010 · Cited by 538
Photoregulated Release of Caged Anticancer Drugs from Gold Nanoparticles
Agasti, S. S., Chompoosor, A., You, C.-C., Ghosh, P., Kim, C. K., & Rotello, V. M. (2009) · Journal of the American Chemical Society · doi:10.1021/ja900591t · Cited by 434
Self-citationNanotechnology for protein delivery: Overview and perspectives
Yu, M., Wu, J., Shi, J., & Farokhzad, O. C. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.10.012 · Cited by 410
Metadata
- Authors
- Hong, R., Fischer, N. O., Verma, A., Goodman, C. M., Emrick, T., & Rotello, V. M.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-01-03
- Volume
- 126
- Issue
- 3
- Pages
- 739-743
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2030520829
- Cited by
- 273
- References
- 1
- FWCI
- 5.36
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
