The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Near-Complete Suppression of Quantum Dot Blinking in Ambient Conditions
Abstract
Colloidal semiconductor quantum dots are attractive fluorophores for multicolor imaging because of broad absorption and narrow emission spectra, and they are brighter and far more photostable than organic dyes. However, severe intermittence in emission (also known as blinking) has been universally observed from single dots and has been considered an intrinsic limitation difficult to overcome. This is unfortunate because growing applications in spectroscopy of single biological molecules and quantum information processing using single photon sources could greatly benefit from long-lasting and nonblinking single-molecule emitters. For instance, in a recent application of single-dot imaging, the tracking of membrane receptors was interrupted frequently due to the stroboscopic nature of recording. Blinking can also reduce the brightness in ensemble imaging via signal saturation. Here we show that the quantum dot blinking can be suppressed with the emission duty cycle approaching 100% while maintaining biocompatibility.
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Logical computation using algorithmic self-assembly of DNA triple-crossover molecules
Mao, C., LaBean, T. H., Reif, J. H., & Seeman, N. C. (2000) · Nature · doi:10.1038/35035038 · Cited by 779
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Shirasaki, Y., Supran, G. J., Bawendi, M. G., & Bulović, V. (2013) · Nature Photonics · doi:10.1038/nphoton.2012.328 · Cited by 2,635
Chen, O., Zhao, J., Chauhan, V. P., Cui, J., Wong, C., Harris, D. K., Wei, H., Han, H.-S., Fukumura, D., Jain, R. K., et al. (2013) · Nature Materials · doi:10.1038/nmat3539 · Cited by 1,430
Quantum Dots as Cellular Probes
Alivisatos, A. P., Gu, W., & Larabell, C. (2005) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.7.060804.100432 · Cited by 1,366
Spectroscopic and Device Aspects of Nanocrystal Quantum Dots
Pietryga, J. M., Park, Y.-S., Lim, J., Fidler, A. F., Bae, W. K., Brovelli, S., & Klimov, V. I. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00169 · Cited by 1,040
Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors
Wegner, K. D., & Hildebrandt, N. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00532e · Cited by 984
Metadata
- Authors
- Hohng, S., & Ha, T.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-01-20
- Volume
- 126
- Issue
- 5
- Pages
- 1324-1325
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2142787912
- Cited by
- 515
- References
- 2
- FWCI
- 21.66
- Type
- journal article
- Language
- en
- Open access
- closed
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