The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Bioaffinity Sensing Using Biologically Functionalized Conducting-Polymer Nanowire
Abstract
A simple, one-step method for fabricating single biologically functionalized conducting-polymer (polypyrrole) nanowire on prepatterned electrodes and its application to biosensing was demonstrated. The biologically functionalized polypyrrole was formed by the electropolymerization of an aqueous solution of pyrrole monomer and the model biomolecule, avidin- or streptavidin-conjugated ZnSe/CdSe quantum dots, within 100 or 200 nm wide by 3 mum long channels between gold electrodes on prefabricated silicon substrate. When challenged with biotin-DNA, the avidin- and streptavidin-polypyrrole nanowires generated a rapid change in resistance to as low as 1 nM, demonstrating the utility of the biomolecule-functionalized nanowire as biosensor. The method offers advantages of direct incorporation of functional biological molecules into the conducting-polymer nanowire during its synthesis, site-specific positioning, built-in electrical contacts, and scalability to high-density nanoarrays over the reported silicon nanowire and carbon nanotube biosensors.
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Cites
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Self-citationStable Ordering in Langmuir-Blodgett Films
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Cited by
Conducting polymers in biomedical engineering
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Electrochemical biosensors: Towards point-of-care cancer diagnostics
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Electrochemistry of Nucleic Acids
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Conductive polymer-based sensors for biomedical applications
Nambiar, S., & Yeow, J. T. W. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.09.046 · Cited by 513
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Sasaki, M., & Goto, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-90460-8 · Cited by 5
Metadata
- Authors
- Ramanathan, K., Bangar, M. A., Yun, M., Chen, W., Myung, N. V., & Mulchandani, A.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-12-23
- Volume
- 127
- Issue
- 2
- Pages
- 496-497
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2072756075
- Cited by
- 401
- References
- 8
- FWCI
- 19.06
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
