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Cited by 313

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Coassembly of Amphiphiles with Opposite Peptide Polarities into Nanofibers

Behanna, Heather A., Donners, Jack J. J. M., Gordon, Alex C., Stupp, Samuel I.·2005·Journal of the American Chemical Society

Abstract

The design, synthesis, and characterization of "reverse" peptide amphiphiles (PAs) with free N-termini is described. Use of an unnatural amino acid modified with a fatty acid tail allows for the synthesis of this new class of PA molecules. The mixing of these molecules with complementary ones containing a free C-terminus results in coassembled structures, as demonstrated by circular dichroism and NOE/NMR spectroscopy. These assemblies show unusual thermal stability when compared to assemblies composed of only one type of PA molecule. This class of reverse PAs has made it possible to create biologically significant assemblies with free N-terminal peptide sequences, which were previously inaccessible, including those derived from phage display methodologies.

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Crossref · 10.1021/ja044863u

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Metadata

Authors
Behanna, H. A., Donners, J. J. J. M., Gordon, A. C., & Stupp, S. I.
Venue
Journal of the American Chemical Society
Published
2005-01-07
Volume
127
Issue
4
Pages
1193-1200
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2038921352
Cited by
313
References
1
FWCI
10.28
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.