The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Single-Walled Carbon Nanotube Biosensors Using Aptamers as Molecular Recognition Elements
Abstract
We report the real-time detection of protein using SWNT-FET-based biosensors comprising DNA aptamers as molecular recognition elements. Anti-thrombin aptamers that are highly specific to serine protein thrombin were immobilized on the sidewall of a SWNT-FET using CDI-Tween linking molecules. The binding of thrombin aptamers to SWNT-FETs causes a rightward shift of the threshold gate voltages, presumably due to the negatively charged backbone of the DNA aptamers. While the addition of thrombin solution causes an abrupt decrease in the conductance of the thrombin aptamer immobilized SWNT-FET, no noticeable change was observed with elastase.
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Cites
Enzyme-coated carbon nanotubes as single-molecule biosensors
Besteman, K., Lee, J.-O., Wiertz, F. G. M., Heering, H. A., & Dekker, C. (2003) · Nano Letters · doi:10.1021/nl034139u · Cited by 1,294
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Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts
Stewart, M. P., Langer, R., & Jensen, K. F. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00678 · Cited by 747
Kuang, Z., Kim, S. N., Crookes-Goodson, W. J., Farmer, B. L., & Naik, R. R. (2010) · ACS Nano · doi:10.1021/nn901365g · Cited by 184
In-Vivo Electrochemistry: What Can We Learn about Living Systems?
Wilson, G. S., & Johnson, M. A. (2008) · Chemical Reviews · doi:10.1021/cr068082i · Cited by 178
Metadata
- Authors
- So, H.-M., Won, K., Kim, Y. H., Kim, B.-K., Ryu, B. H., Na, P. S., Kim, H., & Lee, J.-O.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-08-01
- Volume
- 127
- Issue
- 34
- Pages
- 11906-11907
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2018648960
- Cited by
- 579
- References
- 1
- FWCI
- 10.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- So, H.-M., Won, K., Kim, Y. H., Kim, B.-K., Ryu, B. H., Na, P. S., Kim, H., & Lee, J.-O. (2005). Single-Walled Carbon Nanotube Biosensors Using Aptamers as Molecular Recognition Elements. Journal of the American Chemical Society. https://doi.org/10.1021/ja053094r
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