The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
A Molecular Full-Adder and Full-Subtractor, an Additional Step toward a Moleculator
Abstract
Over the past decade, there has been remarkable progress in the development of molecular logic and arithmetic systems, which has brought chemists closer to the realization of a molecular scale calculator (a Moleculator). This paper describes a significant step in this direction. By integrating past and new approaches for molecular logic reconfiguration, we were able to load advanced arithmetic calculations onto a single molecular species. Exchanging chemical inputs, monitoring at several wavelengths simultaneously, as well as using negative logic for the transmittance mode significantly increase the input and output information channels of the processing molecule. Changing the initial state of the processor is an additional approach used for altering the logical output of the device. Finally, introducing degeneracy to the chemical inputs or, alternatively, controlling their interactions to form identical chemical states minimizes the complexity of realizing three-bits addition and subtraction at the molecular scale. Consequently, using a commercially available fluorescein molecule, acid and base chemical inputs, and a simple UV-vis measurement setup, integration of a full-adder and, for the first time, a full-subtractor is now possible within individual molecules.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A molecular photoionic AND gate based on fluorescent signalling
de Silva, P. A., Gunaratne, N. H. Q., & McCoy, C. P. (1993) · Nature · doi:10.1038/364042a0 · Cited by 1,246
Luminescent sensors and switches in the early 21st century
Callan, J. F., de Silva, A. P., & Magri, D. C. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.05.043 · Cited by 1,123
Absorption and fluorescence properties of fluorescein
Sjöback, R., Nygren, J., & Kubista, M. (1995) · Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy · doi:10.1016/0584-8539(95)01421-p · Cited by 1,069
Digital Processing and Communication with Molecular Switches
Raymo, F. M. (2002) · Advanced Materials · doi:10.1002/1521-4095(20020318)14:6<401::aid-adma401>3.0.co;2-f · Cited by 656
A deoxyribozyme-based molecular automaton
Stojanovic, M. N., & Stefanovic, D. (2003) · Nature Biotechnology · doi:10.1038/nbt862 · Cited by 625
de Silva, A. P., & McClenaghan, N. D. (2004) · Chemistry – A European Journal · doi:10.1002/chem.200305054 · Cited by 612
The pH dependence of fluorescein fluorescence
Martin, M. M., & Lindqvist, L. (1975) · Journal of Luminescence · doi:10.1016/0022-2313(75)90003-4 · Cited by 566
Logic Operations at the Molecular Level. An XOR Gate Based on a Molecular Machine
Credi, A., Balzani, V., Langford, S. J., & Stoddart, J. F. (1997) · Journal of the American Chemical Society · doi:10.1021/ja963572l · Cited by 519
Integration of Logic Functions and Sequential Operation of Gates at the Molecular-Scale
de Silva, A. P., Dixon, I. M., Gunaratne, H. Q. N., Gunnlaugsson, T., Maxwell, P. R. S., & Rice, T. E. (1999) · Journal of the American Chemical Society · doi:10.1021/ja982909b · Cited by 361
Molecular Photoionic AND Logic Gates with Bright Fluorescence and “Off−On” Digital Action
de Silva, A. P., Gunaratne, H. Q. N., & McCoy, C. P. (1997) · Journal of the American Chemical Society · doi:10.1021/ja9712229 · Cited by 328
Cited by
All-photonic multifunctional molecular logic device
Andréasson, J., Pischel, U., Straight, S. D., Moore, T. A., Moore, A. L., & Gust, D. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203456h · Cited by 350
Credi, A. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200700879 · Cited by 314
Small steps towards the development of chemical artificial intelligent systems
Gentili, P. L. (2013) · RSC Advances · doi:10.1039/c3ra44657c · Cited by 70
Metadata
- Authors
- Margulies, D., Melman, G., & Shanzer, A.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-03-18
- Volume
- 128
- Issue
- 14
- Pages
- 4865-4871
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2086686182
- Cited by
- 309
- References
- 20
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
