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Versatile Photosensitizers for Photodynamic Therapy at Infrared Excitation
Open accessAbstract
A new type of photosensitizers used in photodynamic therapy, which is based on photon upconverting nanoparticles, is reported. These photosensitizers are excitable with infrared irradiation and have several times larger tissue penetration depth than the currently available ones. They are brought close to the target cancer cells through antigen−antibody interaction with good specificity and versatility. The design is also flexible in that various photosensitive molecules can be potentially adopted into the design. Results from in vitro experiments demonstrate their promise of becoming the next generation photodynamic therapy drugs.
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Cited by
Photodynamic therapy – mechanisms, photosensitizers and combinations
Kwiatkowski, S., Knap, B., Przystupski, D., Saczko, J., Kędzierska, E., Knap-Czop, K., Kotlińska, J., Michel, O., Kotowski, K., & Kulbacka, J. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.07.049 · Cited by 2,173
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
Zhou, Z., Song, J., Nie, L., & Chen, X. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00271d · Cited by 2,098
Nanoparticles as vehicles for delivery of photodynamic therapy agents
Bechet, D., Couleaud, P., Frochot, C., Viriot, M.-L., Guillemin, F., & Barberi-Heyob, M. (2008) · Trends in Biotechnology · doi:10.1016/j.tibtech.2008.07.007 · Cited by 760
Chen, G., Ohulchanskyy, T. Y., Kumar, R., Ågren, H., & Prasad, P. N. (2010) · ACS Nano · doi:10.1021/nn100457j · Cited by 632
Liu, K., Liu, X., Zeng, Q., Zhang, Y., Tu, L., Liu, T., Kong, X., Wang, Y., Cao, F., Lambrechts, S. A. G., et al. (2012) · ACS Nano · doi:10.1021/nn300436b · Cited by 382
Metadata
- Authors
- Zhang, P., Steelant, W., Kumar, M., & Scholfield, M.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-03-27
- Volume
- 129
- Issue
- 15
- Pages
- 4526-4527
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2048093888
- Cited by
- 600
- References
- 0
- FWCI
- 16.93
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhang, P., Steelant, W., Kumar, M., & Scholfield, M. (2007). Versatile Photosensitizers for Photodynamic Therapy at Infrared Excitation. Journal of the American Chemical Society. https://doi.org/10.1021/ja0700707
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
