The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Compact Cysteine-Coated CdSe(ZnCdS) Quantum Dots for in Vivo Applications
Open accessAbstract
We have developed a versatile nanoparticle construct using a compact cysteine coating on a CdSe(ZnCdS) core(shell) nanocrystal (QD-Cys) that is biologically compatible, exceptionally compact, highly fluorescent, and easily functionalized. The small hydrodynamic diameter of QD-Cys ( approximately 6 nm) allows for renal clearance of these nanoparticles in rat models. Moreover, the ability to directly conjugate to QD-Cys opens up the possibility of functionalized nanocrystals for in vivo targeted imaging, in which small targeting molecules can be appended to QD-Cys, and unbound QDs can be rapidly cleared to achieve high signal/noise ratios and to reduce background toxicity.
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Citations
Cites
Renal clearance of quantum dots
Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476
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Cited by
Design considerations for tumour-targeted nanoparticles
Choi, H. S., Liu, W., Liu, F., Nasr, K., Misra, P., Bawendi, M. G., & Frangioni, J. V. (2010) · Nature Nanotechnology · doi:10.1038/nnano.2009.314 · Cited by 754
Self-citationAtrp in the design of functional materials for biomedical applications
Siegwart, D. J., Oh, J. K., & Matyjaszewski, K. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.08.001 · Cited by 613
Inorganic nanomaterials with rapid clearance for biomedical applications
Wang, X., Zhong, X., Li, J., Liu, Z., & Cheng, L. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00461h · Cited by 509
Luminescent Gold Nanoparticles with Efficient Renal Clearance
Zhou, C., Long, M., Qin, Y., Sun, X., & Zheng, J. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007321 · Cited by 490
Application of semiconductor quantum dots in bioimaging and biosensing
Martynenko, I. V., Litvin, A. P., Purcell-Milton, F., Baranov, A. V., Fedorov, A. V., & Gun'ko, Y. K. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb01425b · Cited by 382
Metadata
- Authors
- Liu, W., Choi, H. S., Zimmer, J. P., Tanaka, E., Frangioni, J. V., & Bawendi, M.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-11-06
- Volume
- 129
- Issue
- 47
- Pages
- 14530-14531
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2094422637
- Cited by
- 415
- References
- 1
- FWCI
- 16.27
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
